Vascular Function and Uterine Fibroids

Overview

  • Study type

    Interventional
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 13-000596
    NCT ID: NCT02123069
    Sponsor Protocol Number: 13-000596

About this study

The purpose of this study is to learn how uterine fibroids may be connected to heart disease and high blood pressure. It is not known what causes fibroids, but they frequently occur in women who also have high blood pressure, heart disease, and stroke. The investigators of this study want to learn if certain changes in the blood vessels or nerve activity can put women at risk for these diseases and for fibroids.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Women 25-50 years old
  • Premenopausal

Exclusion Criteria:

  • Postmenopausal
  • Pregnant or currently breastfeeding
  • Using blood pressure medications or anti-depression medications
  • High blood pressure
  • Diabetes
  • Disease in the kidneys, lungs, or blood vessels
  • Chronic diseases (for example: Crohn's disease, rheumatoid arthritis, bipolar mood disorder, etc.)
  • Smoker
  • High cholesterol
  • BMI higher than 30

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Open for enrollment

Contact information:

Shelly Roberts R.N.

(507)255-2807

roberts.shelly@mayo.edu