The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry


Rochester, Minn.

Trial status:

Open for Enrollment

Why is this study being done?

Spontaneous Coronary Artery Dissection (SCAD) is a relatively rare and poorly understood condition that has been reported to affect more women than men. The coronary arteries consist of three layers, and dissection occurs when two of these layers separate, enabling blood to flow into the space between the layers. As the blood accumulates, this can cause obstruction to normal blood flow within the heart, leading to chest pain, heart attack and even sudden death. The medical community has much to learn about treatment and prevention of this potentially fatal cardiovascular event. Mayo Clinic is conducting two new studies of SCAD. This study consists of building a database/registry of patients with SCAD (whether they have been patients at Mayo Clinic or not) to identify patterns of SCAD incidence, causes and associations that could guide future research. With participant consent, Mayo Clinic staff will request a copy of the original coronary angiogram when SCAD was diagnosed to confirm the diagnosis and determine eligibility. If eligible, study coordinators will contact the participant to provide more information about the studies and request a signed informed consent document.

Who is eligible to participate?

Inclusion Criteria: - Men and women able to give informed consent - Diagnosis of one or more episodes of spontaneous coronary artery dissection (SCAD) Exclusion Criteria: - Lack of angiographic confirmation of SCAD - Iatrogenic dissection or an alternate diagnosis

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