Magnetic Resonance Elastography (MRE) of Uterine Fibroids


Rochester, Minn.

Trial status:

Open for Enrollment

Why is this study being done?

This is a single-site, non-randomized pilot study to determine whether Magnetic Resonance Elastography (MRE) can be optimized for clinical use as part of the patients routine clinical imaging and to correlate with MR signal characteristics of the uterine fibroid. MRE is performed at the end of the examination after the standard Magnetic Resonance Imaging protocol. Aims: Specific Aim 1: To acquire magnetic resonance elastography images on women who have a clinically ordered pelvic magnetic resonance imaging (MRI) for uterine fibroids. Specific Aim 2: To examine the correlation between MRE stiffness values and MR T2 signal characteristics for uterine fibroids. For a subset of patients going on to surgery correlation with pathology can also be performed. This study will seek to determine whether MRE can be performed in the pelvis on a routine clinical basis as well as correlating the MRE findings with magnetic resonance signal characteristics. There are no additional risks to the patient and no additional cost to the MRI exam.

Who is eligible to participate?

Inclusion Criteria: 1. Women able to give informed consent 2. Women having uterine imaging Exclusion Criteria: 1. Women currently pregnant 2. Allergy to either gadolinium or iodinated contrast 3. Severe claustrophobia 4. Weight in excess of 250 pounds

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