Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

Location:

Rochester, Minn.

Trial status:
Open for Enrollment
Why is this study being done?

OBJECTIVES:

       -  Establish a mechanism to bank specimens of tumor cells and host germline DNA from patients with acute lymphoblastic leukemia (ALL) or non-Hodgkin lymphoma at first and subsequent relapse.

       -  Make these specimens available to qualified researchers to study the biology of ALL.

     OUTLINE: This is a multicenter study.

     Patients undergo collection of bone marrow and peripheral blood at diagnosis of relapse and/or at the end of the first month of treatment.

     Patients are followed periodically for up to 10 years.

     PROJECTED ACCRUAL: Not specified.

Who is eligible to participate?

DISEASE CHARACTERISTICS:

         -  Diagnosis of acute lymphoblastic leukemia (ALL) or prior history of non-Hodgkin lymphoma

         -  In first or subsequent marrow relapse with ≥ 25% blasts in bone marrow and/or peripheral blood

         -  Bone marrow and/or peripheral blood samples (≥ 5 mL) required at the time of diagnosis of relapse

       PATIENT CHARACTERISTICS:

         -  Not specified

       PRIOR CONCURRENT THERAPY:

         -  No concurrent systemic antileukemic treatment administered for current relapse

              -  Intrathecal chemotherapy allowed

              -  On-therapy relapse allowed

Last updated:
11/3/2012
NCT ID:
NCT00897325
IRB Number:
07-007836