Aging, Diabetes, Metabolic Syndrome Program

Initiatives

Researchers in the Aging, Diabetes, Metabolic Syndrome Program within the Kogod Center on Aging investigate the relationship between hormones and aging.

In particular, the Aging, Diabetes, Metabolic Syndrome Program capitalizes on the strengths of Mayo Clinic scientists in translating findings about the effects of hormones on aging and age-related diseases into treatments that can help enhance independence.

Focus areas

Hormone production changes as people age, and this can have a cascade of harmful consequences for health, such as loss of muscle mass and decreased metabolic rate. This, in turn, can lead to obesity, insulin resistance and an increased risk of type 2 diabetes and cardiovascular disease.

On the other hand, some hormones, including estrogens and androgens, may play an important role in reducing age-related disability and preventing age-related disease.

Researchers in the Aging, Diabetes, Metabolic Syndrome Program are conducting studies designed to determine how changes that occur during aging mimic progression of obesity, diabetes and cardiovascular disease in younger patients. Understanding more about the similarities and differences in these diseases in younger and older patients can aid in the design of treatments, whether pharmacological or behavioral, such as physical activity and lifestyle interventions.

The Aging, Diabetes, Metabolic Syndrome Program focuses on research about:

  • Atherosclerosis
  • Diabetes
  • Heart attack
  • Hypertension
  • Stroke