About Us

104 members of the EABE Registry Consortium

23 Departments/Divisions

  • Mayo Clinic Arizona
  • Mayo Clinic Jacksonville
  • Mayo Clinic Rochester

NIH CTSA

  • Biostatistics
  • Gastroenterology
  • Genetic Epidemiology
  • Medical Oncology
  • Molecular Biology/Genetics
  • Pathology
  • Psychiatry
  • Pulmonary
  • Radiation Oncology
  • Thoracic Surgery
  • Mayo Clinic Cancer Center

The registry is a:

  • Large bank
    • Fresh-frozen & formalin-fixed tissue
    • Blood
    • Demographic, symptom, quality of life and risk factor data
  • To facilitate identification of:
    • Genetic pathways important in the neoplastic transformation from Barrett's to cancer
    • Novel biomarkers of risk, early detection, response to treatment
    • Novel therapeutic or chemoprevention targets

Phenotypes

Esophagus

  • Barrett's esophagus (BE)
  • Esophageal adenocarcinoma (ACA)
  • Squamous cell carcinoma (SCCA)
  • BE + ACA
  • BE + ACA + SCCA
  • BE + SCCA
  • ACA + SCCA

Gastroesophageal junction

  • ACA
  • BE + ACA

Process

  • Consent once
  • Blood collected once
  • Tissue collected at each procedure (upper endoscopy and surgery)
  • Questionnaires administered by Survey Research Center
    • At baseline
    • Annually