About the SPORE

The Mayo Clinic Pancreatic Cancer SPORE is specifically committed to reducing the incidence and mortality of pancreatic cancer.

The SPORE promotes research focused on understanding the causes of pancreatic cancer and the pathways by which pancreatic cancer progresses. The SPORE also develops interventions to treat pancreatic cancer.

The Pancreatic Cancer SPORE is part of the Gastrointestinal Cancer Program, a formal research program within the Mayo Clinic Cancer Center.

Patients with cancers of the pancreas generally have a poor prognosis, with a five-year survival rate of about only 7 percent. According to the National Cancer Institute (NCI), pancreatic cancer is the third-leading cause of cancer death among men and women in the United States and accounts for more than 41,000 deaths annually.

The Mayo Clinic Pancreatic Cancer SPORE has four translational research projects, all of which focus on cutting-edge approaches to early detection and treatment of pancreatic cancer. The SPORE also has four cores supporting its research.

Broad institutional support throughout Mayo Clinic helps pave the way for the translation of scientific discoveries within the SPORE to help patients with pancreatic cancer and those at risk of developing pancreatic cancer.

The SPORE also nurtures innovative research and interdisciplinary interactions, which attracts scientists and clinicians dedicated to pancreatic cancer research.

Several innovative translational pilot projects are awarded annually through the SPORE's Developmental Research Program, with matching funds from Mayo Clinic. The SPORE's Career Enhancement Program supports one junior faculty member each year.

Funding

The Mayo Clinic Pancreatic Cancer SPORE is funded by the NCI, which awarded Mayo Clinic a five-year grant in September 2014 for $11.3 million. A SPORE, or Specialized Program of Research Excellence, is a cornerstone of the NCI's efforts to promote collaborative, interdisciplinary translational cancer research.

The Mayo Clinic Cancer Center is one of three cancer centers in the U.S. to have a SPORE grant for pancreatic cancer.

Principal investigators

The principal investigators within the Mayo Clinic Pancreatic Cancer SPORE are: