Publications

  1. Burkle CM, Sharp RR, Wijdicks EF. Why brain death is considered death and why there should be no confusion. Neurology. 2014 Oct 14; 83(16):1464-9. Epub 2014 Sep 12.
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  2. Burke W, Appelbaum P, Dame L, Marshall P, Press N, Pyeritz R, Sharp R, Juengst E. The translational potential of research on the ethical, legal, and social implications of genomics. Genet Med. 2014 Jun 19.
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  3. Jarvik GP, Amendola LM, Berg JS, Brothers K, Clayton EW, Chung W, Evans BJ, Evans JP, Fullerton SM, Gallego CJ, Garrison NA, Gray SW, Holm IA, Kullo IJ, Lehmann LS, McCarty C, Prows CA, Rehm HL, Sharp RR, Salama J, Sanderson S, Van Driest SL, Williams Return of genomic results to research participants: the floor, the ceiling, and the choices in between. Am J Hum Genet. 2014 Jun 5; 94(6):818-26. Epub 2014 May 08.
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  4. Koay PP, Sharp RR. Managing Expectational Language: Translational genetic professionals consider the clinical potential of next-generation sequencing technologies. New Genet Soc. 2014 Jun 1; 33(2):126-48.
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  5. Bruce CR, Smith ML, Tawose OM, Sharp RR. Practical guidance for charting ethics consultations. HEC Forum. 2014 Mar; 26(1):79-93.
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  6. Teckman J, Pardee E, Howell RR, Mannino D, Sharp RR, Brantly M, Wanner A, Lamson J. Appropriateness of Newborn Screening for alpha1-Antitrypsin Deficiency. J Pediatr Gastroenterol Nutr. 2014 Feb; 58(2):201-5.
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  7. Kullo IJ, Haddad R, Prows CA, Holm I, Sanderson SC, Garrison NA, Sharp RR, Smith ME, Kuivaniemi H, Bottinger EP, Connolly JJ, Keating BJ, McCarty CA, Williams MS, Jarvik GP. Return of results in the genomic medicine projects of the eMERGE network. Front Genet. 2014; 5:50. Epub 2014 Mar 26.
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  8. Kullo IJ, Haddad R, Prows CA, Holm I, Sanderson SC, Garrison NA, Sharp RR, Smith ME, Kuivaniemi H, Bottinger EP, Connolly J, Keating BJ, McCarty CA, Williams MS, Jarvik GP. Return of genomic results in the genomic medicine projects of the eMERGE network. Frontiers in Genetics. 2014; 5(Feb):50.
  9. Yarborough M, Edwards K, Espinoza P, Geller G, Sarwal A, Sharp R, Spicer P. Relationships hold the key to trustworthy and productive translational science: recommendations for expanding community engagement in biomedical research. Clin Transl Sci. 2013 Aug; 6(4):310-3. Epub 2013 Jan 14.
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  10. Cho D, McGowan ML, Metcalfe J, Sharp RR. Expanded carrier screening in reproductive healthcare: perspectives from genetics professionals. Hum Reprod. 2013 Jun; 28(6):1725-30. Epub 2013 Apr 14.
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  11. Heald B, Plesec T, Liu X, Pai R, Patil D, Moline J, Sharp RR, Burke CA, Kalady MF, Church J, Eng C. Implementation of universal microsatellite instability and immunohistochemistry screening for diagnosing lynch syndrome in a large academic medical center. J Clin Oncol. 2013 Apr 1; 31(10):1336-40. Epub 2013 Feb 11.
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  12. McGowan ML, Sharp RR. Justice in the context of family balancing. Sci Technol Human Values. 2013 Mar 1; 38(2).
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  13. McGowan ML, Cho D, Sharp RR. The changing landscape of carrier screening: expanding technology and options?. Health Matrix Clevel. 2013 Spring; 23(1):15-33.
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  14. McCormick JB, Sharp RR, Ottenberg AL, Reider CR, Taylor HA, Wilfond BS. The establishment of research ethics consultation services (RECS): an emerging research resource. Clin Transl Sci. 2013 Feb; 6(1):40-4. Epub 2012 Dec 06.
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  15. Koay PP, Sharp RR. The role of patient advocacy organizations in shaping genomic science. Annu Rev Genomics Hum Genet. 2013; 14:579-95. Epub 2013 Jul 12.
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  16. Harrison KL, Farrell RM, Brinich MA, Highland J, Mercer M, McCormick JB, Tilburt J, Geller G, Marshall P, Sharp RR. 'Someone should oversee it': patient perspectives on the ethical issues arising with the regulation of probiotics. Health Expect. 2012 Dec 28. [Epub ahead of print]
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  17. Harrison KL, Geller G, Marshall P, Tilburt J, Mercer M, Brinich MA, Highland J, Farrell RM, Sharp RR. Ethical Discourse about the Modification of Food for Therapeutic Purposes: How Patients with Gastrointestinal Diseases View the Good, the Bad, and the Healthy. AJOB Prim Res. 2012 Jul 1; 3(3):12-20. Epub 2012 Jun 19.
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  18. Human Microbiome Project Consortium. A framework for human microbiome research. Nature. 2012 Jun 14; 486(7402):215-21. Epub 2012 Jun 13.
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  19. Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature. 2012 Jun 14; 486(7402):207-14. Epub 2012 Jun 13.
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  20. Uhlmann WR, Sharp RR. Genetic testing integration panels (GTIPs): a novel approach for considering integration of direct-to-consumer and other new genetic tests into patient care. J Genet Couns. 2012 Jun; 21(3):374-81. Epub 2012 Jan 14.
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  21. Teng K, Eng C, Hess CA, Holt MA, Moran RT, Sharp RR, Traboulsi EI. Building an innovative model for personalized healthcare. Cleve Clin J Med. 2012 Apr; 79 Suppl 1:S1-9.
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  22. Beskow LM, Burke W, Fullerton SM, Sharp RR. Offering aggregate results to participants in genomic research: opportunities and challenges. Genet Med. 2012 Apr; 14(4):490-6. Epub 2012 Jan 26.
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  23. Goldenberg AJ, Sharp RR. The ethical hazards and programmatic challenges of genomic newborn screening. JAMA. 2012 Feb 1; 307(5):461-2.
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  24. Lehmann LS, Kaufman DJ, Sharp RR, Moreno TA, Mountain JL, Roberts JS, Green RC. Navigating a research partnership between academia and industry to assess the impact of personalized genetic testing. Genet Med. 2012 Feb; 14(2):268-73. Epub 2012 Jan 12.
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  25. Landy DC, Brinich MA, Colten ME, Horn EJ, Terry SF, Sharp RR. How disease advocacy organizations participate in clinical research: a survey of genetic organizations. Genet Med. 2012 Feb; 14(2):223-8.
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  26. Mercer M, Brinich MA, Geller G, Harrison K, Highland J, James K, Marshall P, McCormick JB, Tilburt J, Achkar JP, Farrell RM, Sharp RR. How patients view probiotics: findings from a multicenter study of patients with inflammatory bowel disease and irritable bowel syndrome. J Clin Gastroenterol. 2012 Feb; 46(2):138-44.
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  27. Caga-anan EC, Smith L, Sharp RR, Lantos JD. Testing children for adult-onset genetic diseases. Pediatrics. 2012 Jan; 129(1):163-7. Epub 2011 Dec 05.
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  28. McCormick JB, Hammer RR, Farrell RM, Geller G, James KM, Loftus EV Jr, Mercer MB, Tilburt JC, Sharp RR. Experiences of patients with chronic gastrointestinal conditions: in their own words. Health Qual Life Outcomes. 2012; 10:25. Epub 2012 Mar 08.
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  29. Silver K, Kukulka G, Gorniewicz J, Rayman K, Sharp R. Genetic susceptibility testing for beryllium: worker knowledge, beliefs, and attitudes. Am J Ind Med. 2011 Jul; 54(7):521-32. Epub 2011 May 06.
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  30. Bruce CR, Smith ML, Hizlan S, Sharp RR. A systematic review of activities at a high-volume ethics consultation service. J Clin Ethics. 2011 Summer; 22(2):151-64.
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  31. Chubak B, Heald B, Sharp RR. Informed consent to microsatellite instability and immunohistochemistry screening for Lynch syndrome. Genet Med. 2011 Apr; 13(4):356-60.
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  32. Sharp RR. Downsizing genomic medicine: approaching the ethical complexity of whole-genome sequencing by starting small. Genet Med. 2011 Mar; 13(3):191-4.
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  33. Goldenberg AJ, Hull SC, Wilfond BS, Sharp RR. Patient perspectives on group benefits and harms in genetic research. Public Health Genomics. 2011; 14(3):135-42. Epub 2010 Oct 08.
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  34. National Heart, Lung and Blood Institute working group, Fabsitz RR, McGuire A, Sharp RR, Puggal M, Beskow LM, Biesecker LG, Bookman E, Burke W, Burchard EG, Church G, Clayton EW, Eckfeldt JH, Fernandez CV, Fisher R, Fullerton SM, Gabriel S, Gachupin F, Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a National Heart, Lung, and Blood Institute working group. Circ Cardiovasc Genet. 2010 Dec; 3(6):574-80.
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  35. Sharp RR, Landy DC. The financing of clinical genetics research by disease advocacy organizations: A review of funding disclosures in biomedical journals. Am J Med Genet A. 2010 Dec; 152A(12):3051-6.
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  36. Sharp RR, McGowan ML, Verma JA, Landy DC, McAdoo S, Carson SA, Simpson JL, McCullough LB. Moral attitudes and beliefs among couples pursuing PGD for sex selection. Reprod Biomed Online. 2010 Dec; 21(7):838-47. Epub 2010 Sep 26.
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  37. International HapMap 3 Consortium, Altshuler DM, Gibbs RA, Peltonen L, Altshuler DM, Gibbs RA, Peltonen L, Dermitzakis E, Schaffner SF, Yu F, Peltonen L, Dermitzakis E, Bonnen PE, Altshuler DM, Gibbs RA, de Bakker PI, Deloukas P, Gabriel SB, Gwilliam R, Integrating common and rare genetic variation in diverse human populations. Nature. 2010 Sep 2; 467(7311):52-8.
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  38. Smith ML, Sharp RR, Weise K, Kodish E. Toward competency-based certification of clinical ethics consultants: a four-step process. J Clin Ethics. 2010 Spring; 21(1):14-22.
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  39. Eng C, Sharp RR. Bioethical and clinical dilemmas of direct-to-consumer personal genomic testing: the problem of misattributed equivalence. Sci Transl Med. 2010 Feb 3; 2(17):17cm5.
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  40. Foster MW, Mulvihill JJ, Sharp RR. Evaluating the utility of personal genomic information. Genet Med. 2009 Aug; 11(8):570-4.
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  41. Yarborough M, Sharp RR. Public trust and research a decade later: what have we learned since Jesse Gelsinger's death? Mol Genet Metab. 2009 May; 97(1):4-5. Epub 2009 Feb 20.
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  42. Sharp RR, Achkar JP, Brinich MA, Farrell RM. Helping patients make informed choices about probiotics: a need for research. Am J Gastroenterol. 2009 Apr; 104(4):809-13.
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  43. Landy DC, Coverdale JH, McCullough LB, Sharp RR. Prepublication review of medical ethics research: cause for concern. Acad Med. 2009 Apr; 84(4):495-7.
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  44. Yarborough M, Fryer-Edwards K, Geller G, Sharp RR. Transforming the culture of biomedical research from compliance to trustworthiness: insights from nonmedical sectors. Acad Med. 2009 Apr; 84(4):472-7.
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  45. Hutchinson JF, Sharp RR. Karma, reincarnation, and medicine: Hindu perspectives on biomedical research. Genomic Medicine. 2009; 2:107-11.
  46. Sharp RR, Yarborough M, Walsh JW, Ethical, Legal, Social Issues Working Group of the Alpha-1 Foundation. Responsible patient advocacy: perspectives from the Alpha-1 Foundation. Am J Med Genet A. 2008 Nov 15; 146A(22):2845-50.
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  47. Hull SC, Sharp RR, Botkin JR, Brown M, Hughes M, Sugarman J, Schwinn D, Sankar P, Bolcic-Jankovic D, Clarridge BR, Wilfond BS. Patients' views on identifiability of samples and informed consent for genetic research. Am J Bioeth. 2008 Oct; 8(10):62-70.
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  48. Foster MW, Sharp RR. Out of sequence: how consumer genomics could displace clinical genetics. Nat Rev Genet. 2008 Jun; 9(6):419.
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  49. Chulada PC, Vahdat HL, Sharp RR, DeLozier TC, Watkins PB, Pusek SN, Blackshear PJ. The Environmental Polymorphisms Registry: a DNA resource to study genetic susceptibility loci. Hum Genet. 2008 Mar; 123(2):207-14. Epub 2008 Jan 10.
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  50. Sharp RR. Teaching rounds and the experience of death as a medical ethicist. J Med Ethics. 2008 Jan; 34(1):60-2.
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  51. Foster MW, Sharp RR. The contractual genome: how direct-to-consumer genomic services may help patients take ownership of their DNA. Personalized Medicine. 2008; 5:399-404.
  52. Yarborough M, Sharp RR. Bioethics consultation and patient advocacy organizations: expanding the dialogue about professional conflicts of interest. Camb Q Healthc Ethics. 2007 Winter; 16(1):74-81.
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  53. Foster MW, Sharp RR. Share and share alike: deciding how to distribute the scientific and social benefits of genomic data. Nat Rev Genet. 2007 Aug; 8(8):633-9. Epub 2007 Jul 03.
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  54. Sharp RR, Foster MW. Grappling with groups: protecting collective interests in biomedical research. J Med Philos. 2007 Jul-Aug; 32(4):321-37.
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  55. Chwang E, Landy DC, Sharp RR. Views regarding the training of ethics consultants: a survey of physicians caring for patients in ICU. J Med Ethics. 2007 Jun; 33(6):320-4.
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  56. Foster MW, Mulvihill JJ, Sharp RR. Investments in cancer genomics: who benefits and who decides. Am J Public Health. 2006 Nov; 96(11):1960-4. Epub 2006 Oct 03.
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  57. Foster MW, Royal CD, Sharp RR. The routinisation of genomics and genetics: implications for ethical practices. J Med Ethics. 2006 Nov; 32(11):635-8.
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  58. Resnik DB, Sharp RR. Protecting third parties in human subjects research. IRB. 2006 Jul-Aug; 28(4):1-7.
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  59. Sharp RR, Yarborough M. Informed trust and the financing of biomedical research. J Law Med Ethics. 2006 Summer; 34(2):460-4.
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  60. Foster MW, Sharp RR. Ethical issues in medical-sequencing research: implications of genotype-phenotype studies for individuals and populations. Hum Mol Genet. 2006 Apr 15; 15 Spec No 1:R45-9.
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  61. Silver K, Sharp RR. Ethical considerations in testing workers for the -Glu69 marker of genetic susceptibility to chronic beryllium disease. J Occup Environ Med. 2006 Apr; 48(4):434-43.
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  62. Brody BA, McCullough LB, Sharp RR. Consensus and controversy in clinical research ethics. JAMA. 2005 Sep 21; 294(11):1411-4.
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  63. Resnik DB, Zeldin DC, Sharp RR. Research on environmental health interventions: ethical problems and solutions. Account Res. 2005 Apr-Jun; 12(2):69-101.
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  64. Foster MW, Sharp RR. Will investments in large-scale prospective cohorts and biobanks limit our ability to discover weaker, less common genetic and environmental contributors to complex diseases? Environ Health Perspect. 2005 Feb; 113(2):119-22.
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  65. Foster MW, Sharp RR. Will investments in biobanks, prospective cohorts, and markers of common patterns of variation benefit other populations for drug response and disease susceptibility gene discovery? Pharmacogenomics J. 2005; 5(2):75-80.
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  66. Foster MW, Sharp RR. Beyond race: towards a whole-genome perspective on human populations and genetic variation. Nat Rev Genet. 2004 Oct; 5(10):790-6.
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  67. Sharp RR, Yudell MA, Wilson SH. Shaping science policy in the age of genomics. Nat Rev Genet. 2004 Apr; 5(4):311-6.
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  68. Sharp RR. Ethical issues in environmental health research. Environ Health Perspect. 2003 Nov; 111(14):1786-8.
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  69. Sharp RR, de Serres F, Newman L, Sandhaus RA, Walsh JW, Hood E, Harry GJ. Environmental, occupational, and genetic risk factors for alpha-1 antitrypsin deficiency. Environ Health Perspect. 2003 Nov; 111(14):1749-52.
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  70. American Thoracic Society, European Respiratory Society. American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med. 2003 Oct 1; 168(7):818-900.
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  71. Lavery JV, Upshur RE, Sharp RR, Hofman KJ. Ethical issues in international environmental health research. Int J Hyg Environ Health. 2003 Aug; 206(4-5):453-63.
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  72. Sharp RR, Foster MW. An analysis of research guidelines on the collection and use of human biological materials from American Indian and Alaskan Native communities. Jurimetrics. 2002 Winter; 42(2):165-86.
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  73. Foster MW, Sharp RR. Race, ethnicity, and genomics: social classifications as proxies of biological heterogeneity. Genome Res. 2002 Jun; 12(6):844-50.
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  74. Sharp RR, Foster MW. Community involvement in the ethical review of genetic research: lessons from American Indian and Alaska Native populations. Environ Health Perspect. 2002 Apr; 110 Suppl 2:145-8.
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  75. Yarborough M, Sharp RR. Restoring and preserving trust in biomedical research. Acad Med. 2002 Jan; 77(1):8-14.
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  76. Christiani DC, Sharp RR, Collman GW, Suk WA. Applying genomic technologies in environmental health research: challenges and opportunities. J Occup Environ Med. 2001 Jun; 43(6):526-33.
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  77. Foster MW, Sharp RR, Mulvihill JJ. Pharmacogenetics, race, and ethnicity: social identities and individualized medical care. Ther Drug Monit. 2001 Jun; 23(3):232-8.
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  78. Sharp RR. The evolution of predictive genetic testing: deciphering gene-environment interactions. Jurimetrics. 2001; 41:145-63.
  79. Sharp RR, Barrett JC. The environmental genome project: ethical, legal, and social implications. Environ Health Perspect. 2000 Apr; 108(4):279-81.
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  80. Sharp RR, Foster MW. Involving study populations in the review of genetic research. J Law Med Ethics. 2000 Spring; 28(1):41-51, 3.
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  81. Foster MW, Sharp RR. Genetic research and culturally specific risks: one size does not fit all. Trends Genet. 2000 Feb; 16(2):93-5.
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  82. Foster MW, Sharp RR, Freeman WL, Chino M, Bernsten D, Carter TH. The role of community review in evaluating the risks of human genetic variation research. Am J Hum Genet. 1999 Jun; 64(6):1719-27.
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  83. Sharp RR, Barrett JC. The Environmental Genome Project and bioethics. Kennedy Inst Ethics J. 1999 Jun; 9(2):175-88.
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