Publications

  1. Wennberg AM, Savica R, Hagen CE, Roberts RO, Knopman DS, Hollman JH, Vemuri P, Jack CR Jr, Petersen RC, Mielke MM. Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging. J Am Geriatr Soc 2016 Nov 21 [Epub ahead of print]
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  2. Savica R, Wennberg AM, Hagen C, Edwards K, Roberts RO, Hollman JH, Knopman DS, Boeve BF, Machulda MM, Petersen RC, Mielke MM. Comparison of Gait Parameters for Predicting Cognitive Decline: The Mayo Clinic Study of Aging. J Alzheimers Dis 2016 Nov 19; 55 (2):559-567
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  3. Biofluid Based Biomarker Professional Interest Area, O'Bryant SE, Mielke MM, Rissman RA, Lista S, Vanderstichele H, Zetterberg H, Lewczuk P, Posner H, Hall J, Johnson L, Fong YL, Luthman J, Jeromin A, Batrla-Utermann R, Villarreal A, Britton G, Snyder PJ, Henriksen K, Grammas P, Gupta V, Martins R, Hampel H. Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic. Alzheimers Dement 2016 Nov 18 [Epub ahead of print]
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  4. Snyder HM, Asthana S, Bain L, Brinton R, Craft S, Dubal DB, Espeland MA, Gatz M, Mielke MM, Raber J, Rapp PR, Yaffe K, Carrillo MC. Sex biology contributions to vulnerability to Alzheimer's disease: A think tank convened by the Women's Alzheimer's Research Initiative. Alzheimers Dement 2016 Nov; 12 (11):1186-1196 Epub 2016 Sept 27
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  5. Krell-Roesch J, Pink A, Roberts RO, Stokin GB, Mielke MM, Spangehl KA, Bartley MM, Knopman DS, Christianson TJ, Petersen RC, Geda YE. Timing of Physical Activity, Apolipoprotein E epsilon4 Genotype, and Risk of Incident Mild Cognitive Impairment. J Am Geriatr Soc 2016 Nov 01 [Epub ahead of print]
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  6. Savica R, Grossardt BR, Bower JH, Ahlskog JE, Mielke MM, Rocca WA. Incidence and time trends of drug-induced parkinsonism: A 30-year population-based study. Mov Disord 2016 Oct 25 [Epub ahead of print]
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  7. Machulda MM, Hagen CE, Wiste HJ, Mielke MM, Knopman DS, Roberts RO, Vemuri P, Lowe VJ, Jack CR Jr, Petersen RC. Practice effects and longitudinal cognitive change in clinically normal older adults differ by Alzheimer imaging biomarker status. Clin Neuropsychol 2016 Oct 11; 1-19 [Epub ahead of print]
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  8. Fabbri E, Yang A, Simonsick EM, Chia CW, Zoli M, Haughey NJ, Mielke MM, Ferrucci L, Coen PM. Circulating ceramides are inversely associated with cardiorespiratory fitness in participants aged 54-96 years from the Baltimore Longitudinal Study of Aging. Aging Cell 2016 Oct; 15 (5):825-31 Epub 2016 May 02
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  9. Knopman DS, Jack CR Jr, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum. Neurobiol Aging 2016 Oct; 46:32-42 Epub 2016 June 16
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  10. Miller VM, Garovic VD, Bailey KR, Lahr BD, Mielke MM, White WM, Jayachandran M. Pregnancy history and blood-borne microvesicles in middle aged women with and without coronary artery calcification. Atherosclerosis 2016 Oct; 253:150-155 Epub 2016 Sept 09
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  11. Kattah AG, Scantlebury DC, Agarwal S, Mielke MM, Rocca WA, Weaver AL, Vaughan LE, Miller VM, Weissgerber TL, White W, Garovic VD. Preeclampsia and ESRD: The Role of Shared Risk Factors. Am J Kidney Dis 2016 Oct 1 Epub 2016 Oct 01
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  12. Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Gunter JL, Senjem ML, Jones DT, Kantarci K, Machulda MM, Mielke MM, Roberts RO, Vemuri P, Reyes DA, Petersen RC. Defining imaging biomarker cut points for brain aging and Alzheimer's disease. Alzheimers Dement 2016 Sep 30 Epub 2016 Sept 30
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  13. Pink A, Przybelski SA, Krell-Roesch J, Stokin GB, Roberts RO, Mielke MM, Spangehl KA, Knopman DS, Jack CR Jr, Petersen RC, Geda YE. Cortical Thickness and Anxiety Symptoms Among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. J Neuropsychiatry Clin Neurosci 2016 Aug 31; appineuropsych15100378 [Epub ahead of print]
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  14. Knopman DS, Jack CR Jr, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia. Neurology 2016 Aug 16; 87 (7):691-8 Epub 2016 July 15
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  15. Staubo SC, Aakre JA, Vemuri P, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Jack CR Jr, Roberts RO. Mediterranean diet, micronutrients and macronutrients, and MRI measures of cortical thickness. Alzheimers Dement 2016 Jul 23 Epub 2016 July 23
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  16. Dage JL, Wennberg AM, Airey DC, Hagen CE, Knopman DS, Machulda MM, Roberts RO, Jack CR Jr, Petersen RC, Mielke MM. Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort. Alzheimers Dement 2016 Jul 18 Epub 2016 July 18
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  17. Krell-Roesch J, Ruider H, Lowe VJ, Stokin GB, Pink A, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Machulda MM, Jack CR, Petersen RC, Geda YE. FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. J Alzheimers Dis 2016 Jul 14; 53 (4):1609-16
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  18. Gonzalez CE, Venkatraman VK, An Y, Landman BA, Davatzikos C, Ratnam Bandaru VV, Haughey NJ, Ferrucci L, Mielke MM, Resnick SM. Peripheral sphingolipids are associated with variation in white matter microstructure in older adults. Neurobiol Aging 2016 Jul; 43:156-63 Epub 2016 Apr 21
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  19. Vassilaki M, Aakre JA, Mielke MM, Geda YE, Kremers WK, Alhurani RE, Machulda MM, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Roberts RO. Multimorbidity and neuroimaging biomarkers among cognitively normal persons. Neurology 2016 May 31; 86 (22):2077-84 Epub 2016 Apr 13
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  20. Kantarci K, Lowe VJ, Lesnick TG, Tosakulwong N, Bailey KR, Fields JA, Shuster LT, Zuk SM, Senjem ML, Mielke MM, Gleason C, Jack CR, Rocca WA, Miller VM. Early Postmenopausal Transdermal 17beta-Estradiol Therapy and Amyloid-beta Deposition. J Alzheimers Dis 2016 May 07; 53 (2):547-56
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  21. Wennberg AM, Gustafson D, Hagen CE, Roberts RO, Knopman D, Jack C, Petersen RC, Mielke MM. Serum Adiponectin Levels, Neuroimaging, and Cognition in the Mayo Clinic Study of Aging. J Alzheimers Dis 2016 May 4; 53 (2):573-81
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  22. Graff-Radford J, Madhavan M, Vemuri P, Rabinstein AA, Cha RH, Mielke MM, Kantarci K, Lowe V, Senjem ML, Gunter JL, Knopman DS, Petersen RC, Jack CR Jr, Roberts RO. Atrial fibrillation, cognitive impairment, and neuroimaging. Alzheimers Dement 2016 Apr; 12 (4):391-8 Epub 2015 Oct 23
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  23. Alhurani RE, Vassilaki M, Aakre JA, Mielke MM, Kremers WK, Machulda MM, Geda YE, Knopman DS, Peterson RC, Roberts RO. Decline in Weight and Incident Mild Cognitive Impairment: Mayo Clinic Study of Aging. JAMA Neurol 2016 Apr; 73 (4):439-46
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  24. White WM, Mielke MM, Araoz PA, Lahr BD, Bailey KR, Jayachandran M, Miller VM, Garovic VD. A history of preeclampsia is associated with a risk for coronary artery calcification 3 decades later. Am J Obstet Gynecol 2016 Apr; 214 (4):519.e1-8 Epub 2016 Feb 10
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  25. Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Machulda M, Lowe VJ, Mielke MM, Roberts RO, Gunter JL, Senjem ML, Geda YE, Rocca WA, Petersen RC, Jack CR Jr. Effect of intellectual enrichment on AD biomarker trajectories: Longitudinal imaging study. Neurology 2016 Mar 22; 86 (12):1128-35 Epub 2016 Feb 24
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  26. Mielke MM, Machulda MM, Hagen CE, Christianson TJ, Roberts RO, Knopman DS, Vemuri P, Lowe VJ, Kremers WK, Jack CR Jr, Petersen RC. Influence of amyloid and APOE on cognitive performance in a late middle-aged cohort. Alzheimers Dement 2016 Mar; 12 (3):281-91 Epub 2015 Nov 19
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  27. Mielke MM, Milic NM, Weissgerber TL, White WM, Kantarci K, Mosley TH, Windham BG, Simpson BN, Turner ST, Garovic VD. Impaired Cognition and Brain Atrophy Decades After Hypertensive Pregnancy Disorders. Circ Cardiovasc Qual Outcomes 2016 Feb; 9 (2 Suppl 1):S70-6
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  28. Roberts RO, Christianson TJ, Kremers WK, Mielke MM, Machulda MM, Vassilaki M, Alhurani RE, Geda YE, Knopman DS, Petersen RC. Association Between Olfactory Dysfunction and Amnestic Mild Cognitive Impairment and Alzheimer Disease Dementia. JAMA Neurol 2016 Jan; 73 (1):93-101
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  29. Petersen RC, Wiste HJ, Weigand SD, Rocca WA, Roberts RO, Mielke MM, Lowe VJ, Knopman DS, Pankratz VS, Machulda MM, Geda YE, Jack CR Jr. Association of Elevated Amyloid Levels With Cognition and Biomarkers in Cognitively Normal People From the Community. JAMA Neurol 2016 Jan; 73 (1):85-92
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  30. Jack CR Jr, Therneau TM, Wiste HJ, Weigand SD, Knopman DS, Lowe VJ, Mielke MM, Vemuri P, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC. Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study. Lancet Neurol 2016 Jan; 15 (1):56-64 Epub 2015 Nov 18
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  31. Savica R, Murray ME, Persson XM, Kantarci K, Parisi JE, Dickson DW, Petersen RC, Ferman TJ, Boeve BF, Mielke MM. Plasma sphingolipid changes with autopsy-confirmed Lewy Body or Alzheimer's pathology. Alzheimers Dement (Amst) 2016; 3:43-50
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  32. Savica R, Murray ME, Persson XM, Kantarci K, Parisi JE, Dickson DW, Petersen RC, Ferman TJ, Boeve BF, Mielke MM. Plasma sphingolipid changes with autopsy-confirmed Lewy body or Alzheimer's pathology Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring 2016; 3:43-50
  33. Wennberg AMV, Gustafson D, Hagen CE, Roberts RO, Knopman D, Jack C Jr, Petersen RC, Mielke MM. Serum adiponectin levels, neuroimaging, and cognition in the Mayo Clinic study of aging Journal Of Alzheimers Disease 2016; 53 (2):573-81
  34. Krell-Roesch J, Ruider H, Lowe VJ, Stokin GB, Pink A, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Machulda MM, Jack CR, Petersen RC, Geda YE. Fdg-pet and neuropsychiatric symptoms among cognitively normal elderly persons: the Mayo Clinic study of aging Journal Of Alzheimers Disease 2016; 53 (4):1609-16
  35. Knopman DS, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum Neurobiology of Aging 2016; 46:32-42
  36. Fabbri E, Yang A, Simonsick EM, Chia CW, Zoli M, Haughey NJ, Mielke MM, Ferrucci L, Coen PM. Circulating ceramides are inversely associated with cardiorespiratory fitness in participants aged 54–96 years from the Baltimore Longitudinal Study of Aging Aging Cell 2016; 15 (5):825-31
  37. Miller VM, Garovic VD, Bailey KR, Lahr BD, Mielke MM, White WM, Jayachandran M. Pregnancy history and blood-borne microvesicles in middle aged women with and without coronary artery calcification Atherosclerosis 2016; 253:150-5
  38. Snyder HM, Asthana S, Bain L, Brinton R, Craft S, Dubal DB, Espeland MA, Gatz M, Mielke MM, Raber J, Rapp PR, Yaffe K, Carrillo MC. Sex biology contributions to vulnerability to Alzheimer's disease: A think tank convened by the Women's Alzheimer's Research Initiative Alzheimer's and Dementia 2016; 12 (11):1186-96
  39. Mielke MM, Bandaru VV, Han D, An Y, Resnick SM, Ferrucci L, Haughey NJ. Demographic and clinical variables affecting mid- to late-life trajectories of plasma ceramide and dihydroceramide species. Aging Cell 2015 Dec; 14 (6):1014-23 Epub 2015 July 20
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  40. Jack CR Jr, Wiste HJ, Weigand SD, Knopman DS, Mielke MM, Vemuri P, Lowe V, Senjem ML, Gunter JL, Reyes D, Machulda MM, Roberts R, Petersen RC. Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings. Brain 2015 Dec; 138 (Pt 12):3747-59 Epub 2015 Sept 30
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  41. Knopman DS, Jack CR Jr, Lundt ES, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Role of beta-Amyloidosis and Neurodegeneration in Subsequent Imaging Changes in Mild Cognitive Impairment. JAMA Neurol 2015 Dec; 72 (12):1475-83
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  42. Knopman DS, Beiser A, Machulda MM, Fields J, Roberts RO, Pankratz VS, Aakre J, Cha RH, Rocca WA, Mielke MM, Boeve BF, Devine S, Ivnik RJ, Au R, Auerbach S, Wolf PA, Seshadri S, Petersen RC. Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging. Neurology 2015 Nov 10; 85 (19):1712-21 Epub 2015 Oct 09
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  43. Gustafson DR, Mielke MM, Keating, Holman SA, Minkoff H, Crystal HA. Leptin, adiponectin and cognition in middle-aged HIV-infected and uninfected women. J Gerontol Geriatr Res.2015;4:(5):240.
  44. Mielke MM, Machulda MM, Hagen CE, Edwards KK, Roberts RO, Pankratz VS, Knopman DS, Jack CR Jr, Petersen RC. Performance of the CogState computerized battery in the Mayo Clinic Study on Aging. Alzheimers Dement 2015 Nov; 11 (11):1367-76 Epub 2015 Apr 06
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  45. Peterlin BL, Mielke MM, Dickens AM, Chatterjee S, Dash P, Alexander G, Vieira RV, Bandaru VV, Dorskind JM, Tietjen GE, Haughey NH. Interictal, circulating sphingolipids in women with episodic migraine: A case-control study. Neurology 2015 Oct 6; 85 (14):1214-23 Epub 2015 Sept 09
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  46. Gustafson DR, Mielke MM, Keating SA, Holman S, Minkoff H, Crystal HA. Leptin, Adiponectin and Cognition in Middle-aged HIV-infected and Uninfected Women. The Brooklyn Women's Interagency HIV Study. J Gerontol Geriatr Res 2015 Oct; 4 (5) Epub 2015 Sept 23
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  47. Rabin LA, Smart CM, Crane PK, Amariglio RE, Berman LM, Boada M, Buckley RF, Chetelat G, Dubois B, Ellis KA, Gifford KA, Jefferson AL, Jessen F, Katz MJ, Lipton RB, Luck T, Maruff P, Mielke MM, Molinuevo JL, Naeem F, Perrotin A, Petersen RC, Rami L, Reisberg B, Rentz DM, Riedel-Heller SG, Risacher SL, Rodriguez O, Sachdev PS, Saykin AJ, Slavin MJ, Snitz BE, Sperling RA, Tandetnik C, van der Flier WM, Wagner M, Wolfsgruber S, Sikkes SA. Reisberg B, Rentz DM, Riedel-Heller SG, Risacher SL, Rodriguez O, Sachdev PS, Saykin AJ, Slavin MJ, Snitz BE, Sperling RA, Tandetnik C, van der Flier WM, Wagner M, Wolfsgruber S, Sikkes SA. Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies. J Alzheimers Dis 2015 Sep 24; 48 Suppl 1:S63-86
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  48. Vassilaki M, Aakre JA, Cha RH, Kremers WK, St Sauver JL, Mielke MM, Geda YE, Machulda MM, Knopman DS, Petersen RC, Roberts RO. Multimorbidity and Risk of Mild Cognitive Impairment. J Am Geriatr Soc 2015 Sep; 63 (9):1783-90 Epub 2015 Aug 27
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  49. Roberts RO, Cha RH, Mielke MM, Geda YE, Boeve BF, Machulda MM, Knopman DS, Petersen RC. Risk and protective factors for cognitive impairment in persons aged 85 years and older. Neurology 2015 May 05; 84 (18):1854-61 Epub 2015 Apr 08
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  50. Jack CR Jr, Wiste HJ, Weigand SD, Knopman DS, Vemuri P, Mielke MM, Lowe V, Senjem ML, Gunter JL, Machulda MM, Gregg BE, Pankratz VS, Rocca WA, Petersen RC. Age, Sex, and APOE epsilon4 Effects on Memory, Brain Structure, and beta-Amyloid Across the Adult Life Span. JAMA Neurol 2015 May; 72 (5):511-9
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  51. Pankratz VS, Roberts RO, Mielke MM, Knopman DS, Jack CR Jr, Geda YE, Rocca WA, Petersen RC. Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of Aging. Neurology 2015 Apr 07; 84 (14):1433-42 Epub 2015 Mar 18
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  52. Dickens AM, Anthony DC, Deutsch R, Mielke MM, Claridge TD, Grant I, Franklin D, Rosario D, Marcotte T, Letendre S, McArthur JC, Haughey NJ. Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients. AIDS 2015 Mar 13; 29 (5):559-69
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  53. Pink A, Stokin GB, Bartley MM, Roberts RO, Sochor O, Machulda MM, Krell-Roesch J, Knopman DS, Acosta JI, Christianson TJ, Pankratz VS, Mielke MM, Petersen RC, Geda YE. Neuropsychiatric symptoms, APOE epsilon4, and the risk of incident dementia: a population-based study. Neurology 2015 Mar 03; 84 (9):935-43 Epub 2015 Feb 04
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  54. Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Preboske GM, Kantarci K, Raman MR, Machulda MM, Mielke MM, Lowe VJ, Senjem ML, Gunter JL, Rocca WA, Roberts RO, Petersen RC, Jack CR Jr. Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly. Brain 2015 Mar; 138 (Pt 3):761-71 Epub 2015 Jan 15
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  55. Mielke MM, Bandaru VV, Han D, An Y, Resnick SM, Ferrucci L, Haughey NJ. Factors affecting longitudinal trajectories of plasma sphingomyelins: the Baltimore Longitudinal Study of Aging. Aging Cell 2015 Feb; 14 (1):112-21 Epub 2014 Oct 24
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  56. Nowrangi MA, Okonkwo O, Lyketsos C, Oishi K, Mori S, Albert M, Mielke MM. Atlas-based diffusion tensor imaging correlates of executive function. J Alzheimers Dis 2015; 44 (2):585-98
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  57. Vassilaki M, Cha RH, Aakre JA, Therneau TM, Geda YE, Mielke MM, Knopman DS, Petersen RC, Roberts RO. Mortality in mild cognitive impairment varies by subtype, sex, and lifestyle factors: the Mayo Clinic Study of Aging. J Alzheimers Dis 2015; 45 (4):1237-45
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  58. Roberts RO, Aakre JA, Cha RH, Kremers WK, Mielke MM, Velgos SN, Geda YE, Knopman DS, Petersen RC. Association of Pancreatic Polypeptide with Mild Cognitive Impairment Varies by APOE epsilon4 Allele. Front Aging Neurosci. 2015; 7:172. Epub 2015 Sep 8
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  59. Mielke MM, Haughey NJ, Bandaru VV, Zetterberg H, Blennow K, Andreasson U, Johnson SC, Gleason CE, Blazel HM, Puglielli L, Sager MA, Asthana S, Carlsson CM. Cerebrospinal fluid sphingolipids, beta-amyloid, and tau in adults at risk for Alzheimer's disease. Neurobiol Aging 2014 Nov; 35 (11):2486-94 Epub 2014 May 27
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  60. Mielke MM, Weigand SD, Wiste HJ, Vemuri P, Machulda MM, Knopman DS, Lowe V, Roberts RO, Kantarci K, Rocca WA, Jack CR Jr, Petersen RC. Independent comparison of CogState computerized testing and a standard cognitive battery with neuroimaging. Alzheimers Dement 2014 Nov; 10 (6):779-89 Epub 2014 Nov 15
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  61. Subjective Cognitive Decline Initiative (SCD-I) Working Group, Jessen F, Amariglio RE, van Boxtel M, Breteler M, Ceccaldi M, Chetelat G, Dubois B, Dufouil C, Ellis KA, van der Flier WM, Glodzik L, van Harten AC, de Leon MJ, McHugh P, Mielke MM, Molinuevo JL, Mosconi L, Osorio RS, Perrotin A, Petersen RC, Rabin LA, Rami L, Reisberg B, Rentz DM, Sachdev PS, de la Sayette V, Saykin AJ, Scheltens P, Shulman MB, Slavin MJ, Sperling RA, Stewart R, Uspenskaya O, Vellas B, Visser PJ, Wagner M.mi L, Reisberg B, Rentz DM, Sachdev PS, de la Sayette V, Saykin AJ, Scheltens P, Shulman MB, Slavin MJ, Sperling RA, Stewart R, Uspenskaya O, Vellas B, Visser PJ, Wagner M, Subjective Cognitive Decline Initiative (SCD-I) Working Group. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimers Dement 2014 Nov; 10 (6):844-52 Epub 2014 May 03
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  62. Rocca WA, Mielke MM, Vemuri P, Miller VM. Sex and gender differences in the causes of dementia: a narrative review. Maturitas 2014 Oct; 79 (2):196-201 Epub 2014 May 27
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  63. Jack CR Jr, Wiste HJ, Weigand SD, Rocca WA, Knopman DS, Mielke MM, Lowe VJ, Senjem ML, Gunter JL, Preboske GM, Pankratz VS, Vemuri P, Petersen RC. Age-specific population frequencies of cerebral beta-amyloidosis and neurodegeneration among people with normal cognitive function aged 50-89 years: a cross-sectional study. Lancet Neurol 2014 Oct; 13 (10):997-1005 Epub 2014 Sept 04
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  64. Knopman DS, Jack CR Jr, Wiste HJ, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC. 18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons. Neurobiol Aging 2014 Sep; 35 (9):2096-106 Epub 2014 Mar 11
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  65. Trushina E, Mielke MM. Recent advances in the application of metabolomics to Alzheimer's Disease. Biochim Biophys Acta 2014 Aug; 1842 (8):1232-9 Epub 2013 June 29
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  66. Vemuri P, Lesnick TG, Przybelski SA, Machulda M, Knopman DS, Mielke MM, Roberts RO, Geda YE, Rocca WA, Petersen RC, Jack CR Jr. Association of lifetime intellectual enrichment with cognitive decline in the older population. JAMA Neurol 2014 Aug; 71 (8):1017-24
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  67. Nicholson AM, Finch NA, Thomas CS, Wojtas A, Rutherford NJ, Mielke MM, Roberts RO, Boeve BF, Knopman DS, Petersen RC, Rademakers R. Progranulin protein levels are differently regulated in plasma and CSF. Neurology 2014 May 27; 82 (21):1871-8 Epub 2014 Apr 25
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  68. Jack CR Jr, Wiste HJ, Knopman DS, Vemuri P, Mielke MM, Weigand SD, Senjem ML, Gunter JL, Lowe V, Gregg BE, Pankratz VS, Petersen RC. Rates of beta-amyloid accumulation are independent of hippocampal neurodegeneration. Neurology 2014 May 06; 82 (18):1605-12 Epub 2014 Apr 04
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  69. Singh B, Mielke MM, Parsaik AK, Cha RH, Roberts RO, Scanlon PD, Geda YE, Christianson TJ, Pankratz VS, Petersen RC. A prospective study of chronic obstructive pulmonary disease and the risk for mild cognitive impairment. JAMA Neurol 2014 May; 71 (5):581-8
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  70. Roberts RO, Knopman DS, Cha RH, Mielke MM, Pankratz VS, Boeve BF, Kantarci K, Geda YE, Jack CR Jr, Petersen RC, Lowe VJ. Diabetes and elevated hemoglobin A1c levels are associated with brain hypometabolism but not amyloid accumulation. J Nucl Med 2014 May; 55 (5):759-64 Epub 2014 Mar 20
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  71. Roberts RO, Knopman DS, Przybelski SA, Mielke MM, Kantarci K, Preboske GM, Senjem ML, Pankratz VS, Geda YE, Boeve BF, Ivnik RJ, Rocca WA, Petersen RC, Jack CR Jr. Association of type 2 diabetes with brain atrophy and cognitive impairment. Neurology 2014 Apr 1; 82 (13):1132-41 Epub 2014 Mar 19
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  72. Steinberg M, Hess K, Corcoran C, Mielke MM, Norton M, Breitner J, Green R, Leoutsakos J, Welsh-Bohmer K, Lyketsos C, Tschanz J. Vascular risk factors and neuropsychiatric symptoms in Alzheimer's disease: the Cache County Study. Int J Geriatr Psychiatry. 2014 Feb; 29(2):153-9. Epub 2013 May 17.
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  73. Roberts RO, Knopman DS, Mielke MM, Cha RH, Pankratz VS, Christianson TJ, Geda YE, Boeve BF, Ivnik RJ, Tangalos EG, Rocca WA, Petersen RC. Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal. Neurology 2014 Jan 28; 82 (4):317-25 Epub 2013 Dec 18
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  74. Mielke MM, Savica R, Wiste HJ, Weigand SD, Vemuri P, Knopman DS, Lowe VJ, Roberts RO, Machulda MM, Geda YE, Petersen RC, Jack CR Jr. Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study. Neurology 2014 Jan 07; 82 (1):70-6 Epub 2013 Dec 26
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  75. Singh B, Parsaik AK, Mielke MM, Erwin PJ, Knopman DS, Petersen RC, Roberts RO. Association of mediterranean diet with mild cognitive impairment and Alzheimer's disease: a systematic review and meta-analysis. J Alzheimers Dis 2014; 39 (2):271-82
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  76. Snyder HM, Carrillo MC, Grodstein F, Henriksen K, Jeromin A, Lovestone S, Mielke MM, O'Bryant S, Sarasa M, Sjogren M, Soares H, Teeling J, Trushina E, Ward M, West T, Bain LJ, Shineman DW, Weiner M, Fillit HM. Developing novel blood-based biomarkers for Alzheimer's disease. Alzheimers Dement 2014 Jan; 10 (1):109-14
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  77. Roberts RO, Knopman DS, Geda YE, Cha RH, Pankratz VS, Baertlein L, Boeve BF, Tangalos EG, Ivnik RJ, Mielke MM, Petersen RC. Association of diabetes with amnestic and nonamnestic mild cognitive impairment. Alzheimers Dement 2014 Jan; 10 (1):18-26 Epub 2013 Apr 03
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  78. Mielke MM, Vemuri P, Rocca WA. Clinical epidemiology of Alzheimer's disease: assessing sex and gender differences. Clin Epidemiol 2014; 6:37-48 Epub 2014 Jan 08
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  79. Geda YE, Roberts RO, Mielke MM, Knopman DS, Christianson TJH, Pankratz VS, Boeve BF, Sochor O, Tangalos EG, Petersen RC, Rocca WA. Baseline neuropsychiatric symptoms and the risk of incident mild cognitive impairment: A population-based study. Am J Psychiatry. 2014; 171(5):572-81.
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  80. Knopman DS, Roberts RO, Pankratz VS, Cha RH, Rocca WA, Mielke MM, Boeve BF, Tangalos EG, Ivnik RJ, Geda YE, Petersen RC. Incidence of dementia among participants and nonparticipants in a longitudinal study of cognitive aging. Am J Epidemiol. 2014; 180(4):414-23.
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