Publications

  1. Emberson J, Lees KR, Lyden P, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis S, Donnan G, Grotta J, Howard G, Kaste M, Koga M, von Kummer R, Lansberg M, Lindley RI, Murray G, Olivot JM, Parsons M, Tilley B, Toni D, Toyoda K, Wahlgren N, Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet. 2014 Aug 05.
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  2. Kumamaru H, Judd SE, Curtis JR, Ramachandran R, Hardy NC, Rhodes JD, Safford MM, Kissela BM, Howard G, Jalbert JJ, Brott TG, Setoguchi S. Validity of Claims-Based Stroke Algorithms in Contemporary Medicare Data: Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study Linked With Medicare Claims. Circ Cardiovasc Qual Outcomes. 2014 Jul; 7(4):611-9. Epub 2014 Jun 24.
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  3. Huang P, Gebhart N, Richelson E, Brott TG, Meschia JF, Zubair AC. Mechanism of mesenchymal stem cell-induced neuron recovery and anti-inflammation. Cytotherapy. 2014 Jun 10.
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  4. Zaidat OO, Castonguay AC, Nguyen TN, Becker KJ, Derdeyn CP, Nelson PK, Amarenco P, Brott TG. Impact of SAMMPRIS on the future of intracranial atherosclerotic disease management: polling results from the ICAD symposium at the International Stroke Conference. J Neurointerv Surg. 2014 Apr 1; 6(3):225-30. Epub 2013 Apr 06.
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  5. Zierler RE, Beach KW, Bergelin RO, Lal BK, Moore WS, Roubin GS, Voeks JH, Brott TG, CREST Investigators. Agreement between site-reported and ultrasound core laboratory results for duplex ultrasound velocity measurements in the Carotid Revascularization Endarterectomy versus Stenting Trial. J Vasc Surg. 2014 Jan; 59(1):2-7. Epub 2013 Sep 19
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  6. Sheffet AJ, Flaxman L, Tom M, Hughes SE, Longbottom ME, Howard VJ, Marler JR, Brott TG. Financial management of a large multisite randomized clinical trial. International Journal of Stroke. 2014; 9(6):811-3.
  7. Vickrey BG, Brott TG, Koroshetz WJ, Stroke Research Priorities Meeting Steering Committee and the National Advisory Neurological Disorders and Stroke Council, National Institute of Neurological Disorders and Stroke. Research priority setting: a summary of the 2012 NINDS Stroke Planning Meeting Report. Stroke. 2013 Aug; 44(8):2338-42. Epub 2013 Jul 02.
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  8. Kennedy RE, Adragni KP, Tiwari HK, Voeks JH, Brott TG, Howard G. Risk-stratified imputation in survival analysis. Clin Trials. 2013 Aug; 10(4):530-9. Epub 2013 Jul 01.
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  9. Meschia JF, Barrett KM, Brott TG. Reperfusion therapy for acute ischemic stroke: how should we react to the Third Interventional Management of Stroke (IMS III) trial? Mayo Clin Proc. 2013 Jul; 88(7):653-7. Epub 2013 May 29.
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  10. Johnston KC, Brott TG. Stroke Progress Review Group: looking back and going forward: introduction. Stroke. 2013 Jun; 44(6 Suppl 1):S110.
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  11. Barrett KM, Ossi RG, Brott TG, Meschia JF. Clinical, anatomic, and procedural durability of carotid revascularization. J Stroke Cerebrovasc Dis. 2013 Apr; 22(3):218-26. Epub 2011 Sep 13.
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  12. Blackshear JL, Brott TG. Ascertainment of any and all neurologic and myocardial damage in carotid revascularization: the key to optimization? Expert Rev Cardiovasc Ther. 2013 Apr; 11(4):469-84.
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  13. Anderson CD, Biffi A, Nalls MA, Devan WJ, Schwab K, Ayres AM, Valant V, Ross OA, Rost NS, Saxena R, Viswanathan A, Worrall BB, Brott TG, Goldstein JN, Brown D, Broderick JP, Norrving B, Greenberg SM, Silliman SL, Hansen BM, Tirschwell DL, Lindgren A, Common variants within oxidative phosphorylation genes influence risk of ischemic stroke and intracerebral hemorrhage. Stroke. 2013 Mar; 44(3):612-9. Epub 2013 Jan 29.
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  14. Heckman MG, Soto-Ortolaza AI, Diehl NN, Rayaprolu S, Brott TG, Wszolek ZK, Meschia JF, Ross OA. Genetic variants associated with myocardial infarction in the PSMA6 gene and Chr9p21 are also associated with ischaemic stroke. Eur J Neurol. 2013 Feb; 20(2):300-8. Epub 2012 Aug 06.
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  15. Timaran CH, Mantese VA, Malas M, Brown OW, Lal BK, Moore WS, Voeks JH, Brott TG, CREST Investigators. Differential outcomes of carotid stenting and endarterectomy performed exclusively by vascular surgeons in the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). J Vasc Surg. 2013 Feb; 57(2):303-8. Epub 2012 Dec 20.
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  16. Brott TG, Halperin JL, Abbara S, Bacharach JM, Barr JD, Bush RL, Cates CU, Creager MA, Fowler SB, Friday G, Hertzberg VS, McIff EB, Moore WS, Panagos PD, Riles TS, Rosenwasser RH, Taylor AJ, Jacobs AK, Smith SC Jr, Anderson JL, Adams CD, Albert N, Buller 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary: a report of the American College of Cardiology Foundation/American Catheter Cardiovasc Interv. 2013 Jan 1; 81(1):E76-123. Epub 2011 Feb 3
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  17. Ross OA, Soto-Ortolaza AI, Heckman MG, Verbeeck C, Serie DJ, Rayaprolu S, Rich SS, Nalls MA, Singleton A, Guerreiro R, Kinsella E, Wszolek ZK, Brott TG, Brown RD Jr, Worrall BB, Meschia JF. NOTCH3 variants and risk of ischemic stroke. PLoS One. 2013; 8(9):e75035. Epub 2013 Sep 23.
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  18. Hill MD, Brooks W, Mackey A, Clark WM, Meschia JF, Morrish WF, Mohr JP, Rhodes JD, Popma JJ, Lal BK, Longbottom ME, Voeks JH, Howard G, Brott TG, CREST Investigators. Stroke after carotid stenting and endarterectomy in the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). Circulation. 2012 Dec 18; 126(25):3054-61. Epub 2012 Nov 16.
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  19. Habersberger J, Brott TG, Roubin GS. Carotid artery stenting: a clinical update. Curr Opin Cardiol. 2012 Nov; 27(6):565-71.
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  20. Kappetein AP, Head SJ, Genereux P, Piazza N, van Mieghem NM, Blackstone EH, Brott TG, Cohen DJ, Cutlip DE, van Es GA, Hahn RT, Kirtane AJ, Krucoff MW, Kodali S, Mack MJ, Mehran R, Rodes-Cabau J, Vranckx P, Webb JG, Windecker S, Serruys PW, Leon MB, Valve Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document (VARC-2). Eur J Cardiothorac Surg. 2012 Nov; 42(5):S45-60. Epub 2012 Oct 1
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  21. Holliday EG, Maguire JM, Evans TJ, Koblar SA, Jannes J, Sturm JW, Hankey GJ, Baker R, Golledge J, Parsons MW, Malik R, McEvoy M, Biros E, Lewis MD, Lincz LF, Peel R, Oldmeadow C, Smith W, Moscato P, Barlera S, Bevan S, Bis JC, Boerwinkle E, Boncoraglio Common variants at 6p21.1 are associated with large artery atherosclerotic stroke. Nat Genet. 2012 Oct; 44(10):1147-51. Epub 2012 Sep 02.
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  22. Vilain KR, Magnuson EA, Li H, Clark WM, Begg RJ, Sam AD 2nd, Sternbergh WC 3rd, Weaver FA, Gray WA, Voeks JH, Brott TG, Cohen DJ, CREST Investigators. Costs and cost-effectiveness of carotid stenting versus endarterectomy for patients at standard surgical risk: results from the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). Stroke. 2012 Sep; 43(9):2408-16. Epub 2012 Jul 19.
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  23. Lal BK, Beach KW, Roubin GS, Lutsep HL, Moore WS, Malas MB, Chiu D, Gonzales NR, Burke JL, Rinaldi M, Elmore JR, Weaver FA, Narins CR, Foster M, Hodgson KJ, Shepard AD, Meschia JF, Bergelin RO, Voeks JH, Howard G, Brott TG, CREST Investigators. Restenosis after carotid artery stenting and endarterectomy: a secondary analysis of CREST, a randomised controlled trial. Lancet Neurol. 2012 Sep; 11(9):755-63. Epub 2012 Aug 2
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  24. Longbottom ME, Roberts JN, Tom M, Hughes SE, Howard VJ, Sheffet AJ, Meschia JF, Brott TG, CREST Investigators. Interventions to increase enrollment in a large multicenter phase 3 trial of carotid stenting vs. endarterectomy. Int J Stroke. 2012 Aug; 7(6):447-53. Epub 2012 May 28.
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  25. Cheng YC, Anderson CD, Bione S, Keene K, Maguire JM, Nalls M, Rasheed A, Zeginigg M, Attia J, Baker R, Barlera S, Biffi A, Bookman E, Brott TG, Brown RD Jr, Chen F, Chen WM, Ciusani E, Cole JW, Cortellini L, Danesh J, Doheny K, Ferrucci L, Grazia Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke? Stroke. 2012 Apr; 43(4):980-6. Epub 2012 Feb 23.
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  26. Voeks JH, Howard G, Roubin GS, Malas MB, Cohen DJ, Sternbergh WC 3rd, Aronow HD, Eskandari MK, Sheffet AJ, Lal BK, Meschia JF, Brott TG, CREST Investigators. Age and outcomes after carotid stenting and endarterectomy: the carotid revascularization endarterectomy versus stenting trial. Stroke. 2011 Dec; 42(12):3484-90. Epub 2011 Oct 06.
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  27. Cheng YC, O'Connell JR, Cole JW, Stine OC, Dueker N, McArdle PF, Sparks MJ, Shen J, Laurie CC, Nelson S, Doheny KF, Ling H, Pugh EW, Brott TG, Brown RD Jr, Meschia JF, Nalls M, Rich SS, Worrall B, Anderson CD, Biffi A, Cortellini L, Furie KL, Rost NS, Genome-wide association analysis of ischemic stroke in young adults. G3 (Bethesda). 2011 Nov; 1(6):505-14. Epub 2011 Nov 01.
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  28. Cohen DJ, Stolker JM, Wang K, Magnuson EA, Clark WM, Demaerschalk BM, Sam AD Jr, Elmore JR, Weaver FA, Aronow HD, Goldstein LB, Roubin GS, Howard G, Brott TG, CREST Investigators. Health-related quality of life after carotid stenting versus carotid endarterectomy: results from CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial). J Am Coll Cardiol. 2011 Oct 4; 58(15):1557-65.
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  29. Meschia JF, Nalls M, Matarin M, Brott TG, Brown RD Jr, Hardy J, Kissela B, Rich SS, Singleton A, Hernandez D, Ferrucci L, Pearce K, Keller M, Worrall BB, Siblings With Ischemic Stroke Study Investigators. Siblings with ischemic stroke study: results of a genome-wide scan for stroke loci. Stroke. 2011 Oct; 42(10):2726-32. Epub 2011 Sep 22.
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  30. Aguilar MI, Brott TG. Update in intracerebral hemorrhage. Neurohospitalist. 2011 Jul; 1(3):148-59.
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  31. Blackshear JL, Cutlip DE, Roubin GS, Hill MD, Leimgruber PP, Begg RJ, Cohen DJ, Eidt JF, Narins CR, Prineas RJ, Glasser SP, Voeks JH, Brott TG, CREST Investigators. Myocardial infarction after carotid stenting and endarterectomy: results from the carotid revascularization endarterectomy versus stenting trial. Circulation. 2011 Jun 7; 123(22):2571-8. Epub 2011 May 23.
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  32. Howard VJ, Lutsep HL, Mackey A, Demaerschalk BM, Sam AD 2nd, Gonzales NR, Sheffet AJ, Voeks JH, Meschia JF, Brott TG, CREST investigators. Influence of sex on outcomes of stenting versus endarterectomy: a subgroup analysis of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). Lancet Neurol. 2011 Jun; 10(6):530-7. Epub 2011 May 5.
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  33. Barrett KM, Brott TG, Brown RD Jr, Carter RE, Geske JR, Graff-Radford NR, McNeil RB, Meschia JF, Mayo Acute Stroke Trial for Enhancing Recovery (MASTER) Study Group. Enhancing recovery after acute ischemic stroke with donepezil as an adjuvant therapy to standard medical care: results of a phase IIA clinical trial. J Stroke Cerebrovasc Dis. 2011 May-Jun; 20(3):177-82. Epub 2011 Feb 03.
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  34. Anderson CD, Biffi A, Rahman R, Ross OA, Jagiella JM, Kissela B, Cole JW, Cortellini L, Rost NS, Cheng YC, Greenberg SM, de Bakker PI, Brown RD Jr, Brott TG, Mitchell BD, Broderick JP, Worrall BB, Furie KL, Kittner SJ, Woo D, Slowik A, Meschia JF, Saxena Common mitochondrial sequence variants in ischemic stroke. Ann Neurol. 2011 Mar; 69(3):471-80. Epub 2010 Sep 13.
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  35. Silver FL, Mackey A, Clark WM, Brooks W, Timaran CH, Chiu D, Goldstein LB, Meschia JF, Ferguson RD, Moore WS, Howard G, Brott TG, CREST Investigators. Safety of stenting and endarterectomy by symptomatic status in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). Stroke. 2011 Mar; 42(3):675-80. Epub 2011 Feb 09.
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  36. Brott T, Halperin J, Abbara S, Bacharach JM, Barr J, Bush R, Cates C, Creager M, Fowler S, Friday G, Hertzberg V, McIff B, Moore W, Panago P, Riles T, Rosenwasser R, Taylor A. ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease Stroke. 2011 Jan 31. [Epub ahead of print]
  37. Brott T, Halperin J, Abbara S, Bacharach JM, Barr J, Bush R, Cates C, Creager M, Fowler S, Friday G, Hertzberg V, McIff B, Moore W, Panago P, Riles T, Rosenwasser R, Taylor A. ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease. Circulation. 2011 Jan 31. [Epub ahead of print]
  38. Meschia JF, Nalls M, Matarin M, Brott TG, Brown RD, Hardy J, Kissela B, Rich S, Singleton A, Hernandez D, Ferrucci L, Pearce K, Keller M, Worrall B, . Revised: Siblings with Ischemic Stroke Study (SWISS): Results of a Genome-wide Scan for Stroke Loci Stroke. 2011.
  39. Meschia JF, Singleton A, Nalls MA, Rich SS, Sharma P, Ferrucci L, Matarin M, Hernandez DG, Pearce K, Brott TG, Brown RD Jr, Hardy J, Worrall BB. Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis. PLoS One. 2011; 6(9):e23161. Epub 2011 Sep 21.
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  40. Perkins WJ, Lanzino G, Brott TG. Carotid stenting vs endarterectomy: new results in perspective. Mayo Clin Proc. 2010 Dec; 85(12):1101-8.
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  41. Rost NS, Rahman RM, Biffi A, Smith EE, Kanakis A, Fitzpatrick K, Lima F, Worrall BB, Meschia JF, Brown RD Jr, Brott TG, Sorensen AG, Greenberg SM, Furie KL, Rosand J. White matter hyperintensity volume is increased in small vessel stroke subtypes. Neurology. 2010 Nov 9; 75(19):1670-7.
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  42. Barrett KM, Brott TG. Management of stenosis of the extracranial internal carotid artery: endarterectomy versus angioplasty and stenting. Curr Treat Options Neurol. 2010 Nov; 12(6):475-82.
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  43. Mantese VA, Timaran CH, Chiu D, Begg RJ, Brott TG, CREST Investigators. The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): stenting versus carotid endarterectomy for carotid disease. Stroke. 2010 Oct; 41(10 Suppl):S31-4.
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  44. Brott TG, Hobson RW 2nd, Howard G, Roubin GS, Clark WM, Brooks W, Mackey A, Hill MD, Leimgruber PP, Sheffet AJ, Howard VJ, Moore WS, Voeks JH, Hopkins LN, Cutlip DE, Cohen DJ, Popma JJ, Ferguson RD, Cohen SN, Blackshear JL, Silver FL, Mohr JP, Lal BK, Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med. 2010 Jul 1; 363(1):11-23. Epub 2010 May 26.
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  45. Rush BK, McNeil RB, Gamble DM, Luke SH, Richie AN, Albers CS, Brown RD, Brott TG, Meschia JF. Behavioral symptoms in long-term survivors of ischemic stroke. J Stroke Cerebrovasc Dis. 2010 Jul-Aug; 19(4):326-32.
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  46. Meschia JF, McNeil RB, Barrett KM, Brott TG, Graff-Radford NR, Brown RD Jr. Mayo Acute Stroke Trial for Enhancing Recovery (MASTER) protocol. J Stroke Cerebrovasc Dis. 2010 Jul-Aug; 19(4):299-310.
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  47. Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, Albers GW, Kaste M, Marler JR, Hamilton SA, Tilley BC, Davis SM, Donnan GA, Hacke W, ECASS, ATLANTIS, NINDS and EPITHET rt-PA Study Group, Allen K, Mau J, Meier D, del Zoppo G, De Silva DA, Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010 May 15; 375(9727):1695-703.
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  48. Hopkins LN, Roubin GS, Chakhtoura EY, Gray WA, Ferguson RD, Katzen BT, Rosenfield K, Goldstein J, Cutlip DE, Morrish W, Lal BK, Sheffet AJ, Tom M, Hughes S, Voeks J, Kathir K, Meschia JF, Hobson RW 2nd, Brott TG. The Carotid Revascularization Endarterectomy versus Stenting Trial: credentialing of interventionalists and final results of lead-in phase. J Stroke Cerebrovasc Dis. 2010 Mar; 19(2):153-62.
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  49. Sheffet AJ, Roubin G, Howard G, Howard V, Moore W, Meschia JF, Hobson RW 2nd, Brott TG. Design of the Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST). Int J Stroke. 2010 Feb; 5(1):40-6.
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  50. Lal BK, Brott TG. The Carotid Revascularization Endarterectomy vs. Stenting Trial completes randomization: lessons learned and anticipated results. J Vasc Surg. 2009 Nov; 50(5):1224-31.
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  51. Matarin M, Brown WM, Dena H, Britton A, De Vrieze FW, Brott TG, Brown RD Jr, Worrall BB, Case LD, Chanock SJ, Metter EJ, Ferruci L, Gamble D, Hardy JA, Rich SS, Singleton A, Meschia JF. Candidate gene polymorphisms for ischemic stroke. Stroke. 2009 Nov; 40(11):3436-42. Epub 2009 Sep 03.
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  52. Richie AN, Trejo J, Bowers CG, McNeil RB, Gamble DM, Luke SH, Brown RD Jr, Brott TG, Kissela BM, Worrall BB, Meschia JF, SWISS Group. Joint Commission primary stroke center certification does not affect proband enrollment: the siblings with ischemic stroke study. J Stroke Cerebrovasc Dis. 2009 Sep-Oct; 18(5):363-6.
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  53. Stroud N, Mazwi TM, Case LD, Brown RD Jr, Brott TG, Worrall BB, Meschia JF, Ischemic Stroke Genetics Study Investigators. Prestroke physical activity and early functional status after stroke. J Neurol Neurosurg Psychiatry. 2009 Sep; 80(9):1019-22. Epub 2009 Jul 14.
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  54. Howard VJ, Voeks JH, Lutsep HL, Mackey A, Milot G, Sam AD 2nd, Tom M, Hughes SE, Sheffet AJ, Longbottom M, Avery JB, Hobson RW 2nd, Brott TG. Does sex matter? Thirty-day stroke and death rates after carotid artery stenting in women versus men: results from the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) lead-in phase. Stroke. 2009 Apr; 40(4):1140-7. Epub 2009 Feb 10.
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  55. Pancioli AM, Broderick J, Brott T, Tomsick T, Khoury J, Bean J, del Zoppo G, Kleindorfer D, Woo D, Khatri P, Castaldo J, Frey J, Gebel J Jr, Kasner S, Kidwell C, Kwiatkowski T, Libman R, Mackenzie R, Scott P, Starkman S, Thurman RJ, CLEAR Trial The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trial. Stroke. 2008 Dec; 39(12):3268-76. Epub 2008 Sep 04.
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  56. Chen DT, Meschia JF, Brott TG, Brown RD, Worrall BB, Siblings with Ischemic Stroke Study Investigators. Stroke genetic research and adults with impaired decision-making capacity: a survey of IRB and investigator practices. Stroke. 2008 Oct; 39(10):2732-5. Epub 2008 Jul 24.
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  57. Kissela BM, Brott TG, Brown RD Jr, Silliman SL, Brown WM, Rich SS, Meschia JF. Proband race/ethnicity affects pedigree completion rate in a genetic study of ischemic stroke. J Stroke Cerebrovasc Dis. 2008 Sep; 17(5):299-302.
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  58. Falkensammer J, Oldenburg WA, Hendrzak AJ, Neuhauser B, Pedraza O, Ferman T, Klocker J, Biebl M, Hugl B, Meschia JF, Hakaim AG, Brott TG. Evaluation of subclinical cerebral injury and neuropsychologic function in patients undergoing carotid endarterectomy. Ann Vasc Surg. 2008 Jul-Aug; 22(4):497-504. Epub 2008 May 27.
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  59. Barrett KM, Brott TG. Carotid artery stenting versus carotid endarterectomy: current status. Neurosurg Clin N Am. 2008 Jul; 19(3):447-58, vi.
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  60. Matarin M, Simon-Sanchez J, Fung HC, Scholz S, Gibbs JR, Hernandez DG, Crews C, Britton A, De Vrieze FW, Brott TG, Brown RD Jr, Worrall BB, Silliman S, Case LD, Hardy JA, Rich SS, Meschia JF, Singleton AB. Structural genomic variation in ischemic stroke. Neurogenetics. 2008 May; 9(2):101-8. Epub 2008 Feb 21.
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  61. Chen DT, Case LD, Brott TG, Brown RD Jr, Silliman SL, Meschia JF, Worrall BB, ISGS Investigators. Impact of restricting enrollment in stroke genetics research to adults able to provide informed consent. Stroke. 2008 Mar; 39(3):831-7. Epub 2008 Feb 07.
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  62. Nichols C, Khoury J, Brott T, Broderick J. Intravenous recombinant tissue plasminogen activator improves arterial recanalization rates and reduces infarct volumes in patients with hyperdense artery sign on baseline computed tomography. J Stroke Cerebrovasc Dis. 2008 Mar-Apr; 17(2):64-8.
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  63. Matarin M, Brown WM, Hardy JA, Rich SS, Singleton AB, Brown RD Jr, Brott TG, Worrall BB, Meschia JF, SWISS Study Group, ISGS Study Group, MSGD Study Group. Association of integrin alpha2 gene variants with ischemic stroke. J Cereb Blood Flow Metab. 2008 Jan; 28(1):81-9. Epub 2007 May 30.
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  64. Freeman WD, Barrett KM, Bestic JM, Meschia JF, Broderick DF, Brott TG. Computer-assisted volumetric analysis compared with ABC/2 method for assessing warfarin-related intracranial hemorrhage volumes. Neurocrit Care. 2008; 9(3):307-12.
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  65. Barrett KM, Brott TG. Carotid endarterectomy versus angioplasty/stenting for carotid stenosis. Curr Atheroscler Rep. 2007 Oct; 9(4):333-40.
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  66. Leslie-Mazwi TM, Brott TG, Brown RD Jr, Worrall BB, Silliman SL, Case LD, Frankel MR, Rich SS, Meschia JF. Sex differences in stroke evaluations in the Ischemic Stroke Genetics Study. J Stroke Cerebrovasc Dis. 2007 Sep-Oct; 16(5):187-93.
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  67. Thompson KM, Gerlach SY, Jorn HK, Larson JM, Brott TG, Files JA. Advances in the care of patients with intracerebral hemorrhage. Mayo Clin Proc. 2007 Aug; 82(8):987-90.
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  68. Meschia JF, Brott TG, Hobson RW 2nd. Diagnosis and invasive management of carotid atherosclerotic stenosis. Mayo Clin Proc. 2007 Jul; 82(7):851-8.
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  69. Barrett KM, Freeman WD, Weindling SM, Brott TG, Broderick DF, Heckman MG, Crook JE, Divertie GD, Meschia JF. Brain injury after cardiopulmonary arrest and its assessment with diffusion-weighted magnetic resonance imaging. Mayo Clin Proc. 2007 Jul; 82(7):828-35.
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  70. Matarin M, Brown WM, Scholz S, Simon-Sanchez J, Fung HC, Hernandez D, Gibbs JR, De Vrieze FW, Crews C, Britton A, Langefeld CD, Brott TG, Brown RD Jr, Worrall BB, Frankel M, Silliman S, Case LD, Singleton A, Hardy JA, Rich SS, Meschia JF. A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. Lancet Neurol. 2007 May; 6(5):414-20.
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  71. Worrall BB, Brott TG, Brown RD Jr, Brown WM, Rich SS, Arepalli S, Wavrant-De Vrieze F, Duckworth J, Singleton AB, Hardy J, Meschia JF, SWISS, ISGS and MSGD I. IL1RN VNTR polymorphism in ischemic stroke: analysis in 3 populations. Stroke. 2007 Apr; 38(4):1189-96.
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  72. Wiklund PG, Brown WM, Brott TG, Stegmayr B, Brown RD Jr, Nilsson-Ardnor S, Hardy JA, Kissela BM, Singleton A, Holmberg D, Rich SS, Meschia JF. Lack of aggregation of ischemic stroke subtypes within affected sibling pairs. Neurology. 2007 Feb 6; 68(6):427-31.
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  73. Brott TG. Novel approaches to stroke prevention in atrial fibrillation: introduction. Stroke. 2007 Feb; 38(2 Suppl):614.
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  74. Barrett KM, Brott TG, Brown RD Jr, Frankel MR, Worrall BB, Silliman SL, Case LD, Rich SS, Meschia JF, Ischemic Stroke Genetics Study Group. Sex differences in stroke severity, symptoms, and deficits after first-ever ischemic stroke. J Stroke Cerebrovasc Dis. 2007 Jan-Feb; 16(1):34-9.
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  75. Barrett KM, Brott TG. Carotid artery stenting versus carotid endarterectomy: current status. Neurol Clin. 2006 Nov; 24(4):681-95.
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  76. Meschia JF, Barrett KM, Chukwudelunzu F, Brown WM, Case LD, Kissela BM, Brown RD Jr, Brott TG, Olson TS, Rich SS, Silliman S, Worrall BB, Siblings with Ischemic Stroke Study (SWISS) Investigators. Interobserver agreement in the trial of org 10172 in acute stroke treatment classification of stroke based on retrospective medical record review. J Stroke Cerebrovasc Dis. 2006 Nov-Dec; 15(6):266-72.
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  77. Meschia JF, Case LD, Worrall BB, Brown RD Jr, Brott TG, Frankel M, Silliman S, Rich SS, Ischemic Stroke Genetics Study Group. Family history of stroke and severity of neurologic deficit after stroke. Neurology. 2006 Oct 24; 67(8):1396-402.
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  78. Jauch EC, Lindsell CJ, Adeoye O, Khoury J, Barsan W, Broderick J, Pancioli A, Brott T. Lack of evidence for an association between hemodynamic variables and hematoma growth in spontaneous intracerebral hemorrhage. Stroke. 2006 Aug; 37(8):2061-5. Epub 2006 Jun 22.
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  79. He Z, Meschia JF, Brott TG, Dickson DW, McKinney M. Aging is neuroprotective during global ischemia but leads to increased caspase-3 and apoptotic activity in hippocampal neurons. Curr Neurovasc Res. 2006 Aug; 3(3):181-6.
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  80. Levy JH, Fingerhut A, Brott T, Langbakke IH, Erhardtsen E, Porte RJ. Recombinant factor VIIa in patients with coagulopathy secondary to anticoagulant therapy, cirrhosis, or severe traumatic injury: review of safety profile. Transfusion. 2006 Jun; 46(6):919-33.
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  81. Dominguez R, Vila JF, Augustovski F, Irazola V, Castillo PR, Rotta Escalante R, Brott TG, Meschia JF. Spanish cross-cultural adaptation and validation of the National Institutes of Health Stroke Scale. Mayo Clin Proc. 2006 Apr; 81(4):476-80.
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  183. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. Endarterectomy for asymptomatic carotid artery stenosis. JAMA. 1995 May 10; 273(18):1421-8.
  184. Loncaric S, Dhawan AP, Broderick J, Brott T. 3-D image analysis of intra-cerebral brain hemorrhage from digitized CT films. Comput Methods Programs Biomed. 1995 Apr; 46(3):207-16.
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  185. Tomsick TA, Ernst RJ, Tew JM, Brott TG, Breneman JC. Adult choroidal vein of Galen malformation. AJNR Am J Neuroradiol. 1995 Apr; 16(4 Suppl):861-5.
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  186. Broderick JP, Hagen T, Brott T, Tomsick T. Hyperglycemia and hemorrhagic transformation of cerebral infarcts. Stroke. 1995 Mar; 26(3):484-7.
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  189. Lyden P, Brott T, Tilley B, Welch KM, Mascha EJ, Levine S, Haley EC, Grotta J, Marler J. Improved reliability of the NIH Stroke Scale using video training. NINDS TPA Stroke Study Group. Stroke. 1994 Nov; 25(11):2220-6.
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  190. Barsan WG, Brott TG, Broderick JP, Haley EC Jr, Levy DE, Marler JR. Urgent therapy for acute stroke. Effects of a stroke trial on untreated patients. Stroke. 1994 Nov; 25(11):2132-7.
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  191. Adams HP Jr, Brott TG, Crowell RM, Furlan AJ, Gomez CR, Grotta J, Helgason CM, Marler JR, Woolson RF, Zivin JA. Guidelines for the management of patients with acute ischemic stroke. A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke. 1994 Sep; 25(9):1901-14.
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  192. Broderick JP, Brott TG, Duldner JE, Tomsick T, Leach A. Initial and recurrent bleeding are the major causes of death following subarachnoid hemorrhage. Stroke. 1994 Jul; 25(7):1342-7.
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  193. Brott T, Tomsick T, Feinberg W, Johnson C, Biller J, Broderick J, Kelly M, Frey J, Schwartz S, Blum C. Baseline silent cerebral infarction in the Asymptomatic Carotid Atherosclerosis Study. Stroke. 1994 Jun; 25(6):1122-9.
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  194. Broderick J, Brott T, Tomsick T, Tew J, Duldner J, Huster G. Management of intracerebral hemorrhage in a large metropolitan population. Neurosurgery. 1994 May; 34(5):882-7; discussion 887.
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  195. Brott T, Broderick J, Kothari R. Thrombolytic therapy for stroke. Curr Opin Neurol. 1994 Feb; 7(1):25-35.
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  196. Levy DE, Brott TG, Haley EC Jr, Marler JR, Sheppard GL, Barsan W, Broderick JP. Factors related to intracranial hematoma formation in patients receiving tissue-type plasminogen activator for acute ischemic stroke. Stroke. 1994 Feb; 25(2):291-7.
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  197. Brott T. Silent cerebral infarction/lacunes. Journal of Stroke and Cerebrovascular Diseases. 1994; 4:S44-S46.
  198. Barsan WG, Brott TG, Broderick JP, Haley EC, Levy DE, Marler JR. Time of hospital presentation in patients with acute stroke. Arch Intern Med. 1993 Nov 22; 153(22):2558-61.
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  199. Broderick J, Brott T, Barsan W, Haley EC, Levy D, Marler J, Sheppard G, Blum C. Blood pressure during the first minutes of focal cerebral ischemia. Ann Emerg Med. 1993 Sep; 22(9):1438-43.
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  200. Broderick J, Talbot GT, Prenger E, Leach A, Brott T. Stroke in children within a major metropolitan area: the surprising importance of intracerebral hemorrhage. J Child Neurol. 1993 Jul; 8(3):250-5.
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  201. Haley EC Jr, Brott TG, Sheppard GL, Barsan W, Broderick J, Marler JR, Kongable GL, Spilker J, Massey S, Hansen CA. Pilot randomized trial of tissue plasminogen activator in acute ischemic stroke. The TPA Bridging Study Group. Stroke. 1993 Jul; 24(7):1000-4.
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  203. Broderick JP, Brott T, Tomsick T, Miller R, Huster G. Intracerebral hemorrhage more than twice as common as subarachnoid hemorrhage. J Neurosurg. 1993 Feb; 78(2):188-91.
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  204. Brott T, Broderick JP. Intracerebral hemorrhage. Heart Disease & Stroke. 1993 Jan-Feb; 2(1):59-63.
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  205. McDowell FH, Brott T, Goldstein M, Grotta J, Heros R, Latchaw R, Robertson J, Sherman D, Starkman S, Toole J. The emergency treatment of stroke: the first six hours. Journal of Stroke and Cerebrovascular Diseases. 1993; 3:133-144.
  206. Broderick J, Brott T, Tomsick T, Leach A. Lobar hemorrhage in the elderly. The undiminishing importance of hypertension. Stroke. 1993; 24(1):49-51.
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  207. Adams HP, Brott T, Crowell R. Adult basic life support - Stroke. Health Care Provider's Manual for Basic Life Support and Textbook of Advanced Life Support Stroke. 1993.
  208. Brott T. Utility of the National Institutes of Health stroke scale. Cerebrovasc Dis. 1992 Jul-Aug; 2(4):241-2.
  209. Brott TG, Haley EC Jr, Levy DE, Barsan W, Broderick J, Sheppard GL, Spilker J, Kongable GL, Massey S, Reed R. Urgent therapy for stroke. Part I. Pilot study of tissue plasminogen activator administered within 90 minutes. Stroke. 1992 May; 23(5):632-40.
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  210. Haley EC Jr, Levy DE, Brott TG, Sheppard GL, Wong MC, Kongable GL, Torner JC, Marler JR. Urgent therapy for stroke. Part II. Pilot study of tissue plasminogen activator administered 91-180 minutes from onset. Stroke. 1992 May; 23(5):641-5.
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  211. Broderick JP, Brott T, Tomsick T, Huster G, Miller R. The risk of subarachnoid and intracerebral hemorrhages in blacks as compared with whites. N Engl J Med. 1992 Mar 12; 326(11):733-6.
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  212. Brott T. Thrombolytic therapy. Neurol Clin. 1992 Feb; 10(1):219-32.
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  213. Tomsick T, Brott T, Barsan W, Broderick J, Haley EC, Spilker J. Thrombus localization with emergency cerebral CT. AJNR Am J Neuroradiol. 1992 Jan-Feb; 13(1):257-63.
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  214. Levine SR, Brott TG. Thrombolytic therapy in cerebrovascular disorders. Prog Cardiovasc Dis. 1992 Jan-Feb; 34(4):235-62.
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  215. Adams HP, Brott T, Crowell R. Emergency cardiac care committee and subcommittees, American Heart Association. JAMA. 1992; 268:2242-2244.
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  216. Brott T, Stump D. Overview of hemostasis and thrombosis. Semin Neurol. 1991 Dec; 11(4):305-13.
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  217. , North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med. 1991 Aug 15; 325(7):445-53.
  218. Brott T. Prevention and management of medical complications of the hospitalized elderly stroke patient. Clin Geriatr Med. 1991 Aug; 7(3):475-82.
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  219. Brott T. Thrombolytic therapy for stroke. Cerebrovascular & Brain Metabolism Reviews. 1991 Summer; 3(2):91-113.
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  220. Brott T. Neurological complications of clotting disorders. Seminars in Neurology 11 1991.
  221. Tomsick TA, Brott TG, Chambers AA, Fox AJ, Gaskill MF, Lukin RR, Pleatman CW, Wiot JG, Bourekas E. Hyperdense middle cerebral artery sign on CT: efficacy in detecting middle cerebral artery thrombosis. AJNR Am J Neuroradiol. 1990 May; 11(3):473-7.
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  222. Olinger CP, Adams HP Jr, Brott TG, Biller J, Barsan WG, Toffol GJ, Eberle RW, Marler JR. High-dose intravenous naloxone for the treatment of acute ischemic stroke. Stroke. 1990 May; 21(5):721-5.
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  223. Broderick JP, Brott TG, Tomsick T, Barsan W, Spilker J. Ultra-early evaluation of intracerebral hemorrhage. J Neurosurg. 1990 Feb; 72(2):195-9.
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  224. Barsan W, Brott T. Treatment of acute ischemic stroke. Stroke, Clinical Updates. 1990; 1:1-4.
  225. Barsan WG, Brott TG, Olinger CP, Marler JR. Early treatment for acute ischemic stroke. Ann Intern Med. 1989 Sep 15; 111(6):449-51.
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  226. Barsan WG, Olinger CP, Adams HP Jr, Brott TG, Eberle R, Biller J, Biros M, Marler J. Use of high dose naloxone in acute stroke: possible side-effects. Crit Care Med. 1989 Aug; 17(8):762-7.
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  227. Brott T, Marler JR, Olinger CP, Adams HP Jr, Tomsick T, Barsan WG, Biller J, Eberle R, Hertzberg V, Walker M. Measurements of acute cerebral infarction: lesion size by computed tomography. Stroke. 1989 Jul; 20(7):871-5.
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  228. Brott T, Adams HP Jr, Olinger CP, Marler JR, Barsan WG, Biller J, Spilker J, Holleran R, Eberle R, Hertzberg V. Measurements of acute cerebral infarction: a clinical examination scale. Stroke. 1989 Jul; 20(7):864-70.
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  229. Brott T, Reed RL. Intensive care for acute stroke in the community hospital setting. The first 24 hours. Stroke. 1989 May; 20(5):694-7.
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  230. Bienenfeld D, Brott T. Capgras' syndrome following minor head trauma. J Clin Psychiatry. 1989 Feb; 50(2):68-9.
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  231. Timerding BL, Barsan WG, Hedges JR, Brott TG, VanLigten PF, Spilker JA, Olinger CP. Stroke patient evaluation in the emergency department before pharmacologic therapy. Am J Emerg Med. 1989 Jan; 7(1):11-5.
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  232. Tomsick TA, Brott TG, Olinger CP, Barsan W, Spilker J, Eberle R, Adams H. Hyperdense middle cerebral artery: incidence and quantitative significance. Neuroradiology. 1989; 31(4):312-5.
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  233. Barsan WG, Brott TG, Olinger CP, Adams HP Jr, Haley EC Jr, Levy DE. Identification and entry of the patient with acute cerebral infarction. Ann Emerg Med. 1988 Nov; 17(11):1192-5.
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  234. Olinger CP, Brott TG, Barsan WG, Hedges JR, Glas-Greenwalt P, Pollak VE, Spilker J, Eberle R. Use of ancrod in acute or progressing ischemic cerebral infarction. Ann Emerg Med. 1988 Nov; 17(11):1208-9.
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  235. Brott T, Haley EC, Levy DE, Barsan WG, Reed RL, Olinger CP, Marler JR. The investigational use of tPA for stroke. Ann Emerg Med. 1988 Nov; 17(11):1202-5.
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  236. Adams HP Jr, Olinger CP, Marler JR, Biller J, Brott TG, Barsan WG, Banwart K. Comparison of admission serum glucose concentration with neurologic outcome in acute cerebral infarction. A study in patients given naloxone. Stroke. 1988 Apr; 19(4):455-8.
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  237. Brott T, Mandybur TI. Case-control study of clinical outcome after aneurysmal subarachnoid hemorrhage. Neurosurgery. 1986 Dec; 19(6):891-5.
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  238. Brott T, Thalinger K, Hertzberg V. Hypertension as a risk factor for spontaneous intracerebral hemorrhage. Stroke. 1986 Nov-Dec; 17(6):1078-83.
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  239. Kempczinski RF, Brott TG, Labutta RJ. The influence of surgical specialty and caseload on the results of carotid endarterectomy. J Vasc Surg. 1986 Jun; 3(6):911-6.
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  240. Brott TG, Labutta RJ, Kempczinski RF. Changing patterns in the practice of carotid endarterectomy in a large metropolitan area. JAMA. 1986 May 16; 255(19):2609-12.
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  241. Adams HP Jr, Olinger CP, Barsan WG, Butler MJ, Graff-Radford NR, Brott TG, Biller J, Damasio H, Tomsick T, Goldberg M, et al. A dose-escalation study of large doses of naloxone for treatment of patients with acute cerebral ischemia. Stroke. 1986 May-Jun; 17(3):404-9.
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  242. Brott TG, Gelfand MJ, Williams CC, Spilker JA, Hertzberg VS. Frequency and patterns of abnormality detected by iodine-123 amine emission CT after cerebral infarction. Radiology. 1986 Mar; 158(3):729-34.
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  243. Brott T, Thalinger K. The practice of carotid endarterectomy in a large metropolitan area. Stroke. 1984 Nov-Dec; 15(6):950-5.
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  244. Brott T, Leviton A. Violence. Headache. 1976 Nov; 16(5):203-9.
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