Publications

  1. Tan N, Sampath R, Abu Saleh OM, Tweet MS, Jevremovic D, Alniemi S, Wengenack NL, Sampathkumar P, Badley AD. Disseminated Mycobacterium chimaera Infection After Cardiothoracic Surgery. Open Forum Infect Dis 2016 Sep; 3 (3):ofw131 Epub 2016 June 16
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  2. Kasten MJ, Cummins NW, Badley AD, Sampath R, Temesgen Z, Whitaker JA, Wilson JW, Yao JD, Zeuli JD, Rizza SA. Twenty years of human immunodeficiency virus care at the Mayo Clinic: Past, present, and future World Journal of Virology.5:(2):63-67.
  3. Cummins NW, Badley AD, Kasten MJ, Sampath R, Temesgen Z, Whitaker JA, Wilson JW, Yao JD, Zeuli J, Rizza SA. Twenty years of human immunodeficiency virus care at the Mayo Clinic: Past, present and future. World J Virol 2016 May 12; 5 (2):63-7
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  4. Cummins NW, Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, de Araujo Correia MC, Sampath R, Rizza SA, O'Brien D, Yao JD, Kaufmann SH, Badley AD. Prime, Shock, and Kill: Priming CD4 T Cells from HIV Patients with a BCL-2 Antagonist before HIV Reactivation Reduces HIV Reservoir Size. J Virol 2016 Apr; 90 (8):4032-48 Epub 2016 Mar 28
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  5. Sampath R, Cummins NW, Badley AD. Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIV. J Cell Death 2016; 9:9-17 Epub 2016 Sept 27
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  6. Sampath R, Cummins NW, Badley AD. Casp8p41: The protean mediator of death in CD4 T-cells that replicate hiv Journal of Cell Death 2016; 9:9-17
  7. INSIGHT Study Group, Cummins NW, Neuhaus J, Chu H, Neaton J, Wyen C, Rockstroh JK, Skiest DJ, Boyd MA, Khoo S, Rotger M, Telenti A, Weinshilboum R, Badley AD. Investigation of Efavirenz Discontinuation in Multi-ethnic Populations of HIV-positive Individuals by Genetic Analysis. EBioMedicine 2015 Jul; 2 (7):706-12 Epub 2015 May 12
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  8. Cummins NW, Badley AD. Can HIV Be Cured and Should We Try? Mayo Clin Proc 2015 Jun; 90 (6):705-9 Epub 2015 May 02
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  9. Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, Cummins NW, Correia C, Meng XW, Tarara JE, Ramirez-Alvarado M, Katzmann DJ, Ochsenbauer C, Kappes JC, Kaufmann SH, Badley AD. Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation. J Cell Biol 2014 Sep 29; 206 (7):867-76 Epub 2014 Sept 22
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  10. INSIGHT SMART Study Group, Cummins NW, Neuhaus J, Sainski AM, Strausbauch MA, Wettstein PJ, Lewin SR, Plana M, Rizza SA, Temesgen Z, Touloumi G, Freiberg M, Neaton J, Badley AD. Short communication: CD4 T cell declines occurring during suppressive antiretroviral therapy reflect continued production of Casp8p41. AIDS Res Hum Retroviruses 2014 May; 30 (5):476-9 Epub 2014 Feb 14
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  11. Cummins NW, Sainski AM, Natesampillai S, Bren GD, Badley AD. Choice of antiretroviral therapy differentially impacts survival of HIV-infected CD4 T cells. Mol Cell Ther 2014; 2:1 Epub 2014 Jan 03
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  12. Cummins NW, Badley AD. Making sense of how HIV kills infected CD4 T cells: implications for HIV cure. Mol Cell Ther 2014; 2:20 Epub 2014 July 03
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  13. Badley AD. "Much ado to achieve nothing: prospects for curing HIV infection". Mol Cell Ther 2014; 2:9 Epub 2014 Mar 26
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  14. Cummins NW, Badley AD. Anti-apoptotic mechanisms of HIV: lessons and novel approaches to curing HIV. Cell Mol Life Sci. 2013 Sep; 70(18):3355-63. Epub 2012 Dec 30.
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  15. Badley AD, Sainski A, Wightman F, Lewin SR. Altering cell death pathways as an approach to cure HIV infection. Cell Death Dis 2013 Jul 11; 4:e718 Epub 2013 July 11
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  16. Rizza SA, Cummins N, El Atrouni W, Badley AD, Dababneh A, Temesgen Z. Advances in the treatment of HIV and chronic hepatitis C virus infection: A report from the 20th conference on retroviruses and opportunistic infections (croi 2013). Drugs Future. 2013; 38(5):325-33.
  17. Trushin SA, Carena AA, Bren GD, Rizza SA, Dong X, Abraham RS, Badley AD. SDF-1alpha degrades whereas glycoprotein 120 upregulates Bcl-2 interacting mediator of death extralong isoform: implications for the development of T cell memory. J Immunol 2012 Aug 15; 189 (4):1835-42 Epub 2012 July 16
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  18. Cummins NW, Weaver EA, May SM, Croatt AJ, Foreman O, Kennedy RB, Poland GA, Barry MA, Nath KA, Badley AD. Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice. FASEB J 2012 Jul; 26 (7):2911-8 Epub 2012 Apr 06
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  19. Baker JV, Neuhaus J, Duprez D, Freiberg M, Bernardino JI, Badley AD, Nixon DE, Lundgren JD, Tracy RP, Neaton JD, INSIGHT SMART Study Group. HIV replication, inflammation, and the effect of starting antiretroviral therapy on plasma asymmetric dimethylarginine, a novel marker of endothelial dysfunction. J Acquir Immune Defic Syndr. 2012 Jun 1; 60(2):128-34.
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  20. Schnepple DJ, Shepard B, Bren GD, Cummins NW, Natesampillai S, Trushin S, Algeciras-Schimnich A, Meng XW, Sainski AM, Rizza SA, Kaufmann SH, Badley AD. Isolation of a TRAIL antagonist from the serum of HIV-infected patients. J Biol Chem 2011 Oct 14; 286 (41):35742-54 Epub 2011 Aug 22
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  21. Sainski AM, Natesampillai S, Cummins NW, Bren GD, Taylor J, Saenz DT, Poeschla EM, Badley AD. The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak. J Virol 2011 Aug; 85 (16):7965-75 Epub 2011 June 08
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  22. Cummins NW, Klicpera A, Sainski AM, Bren GD, Khosla S, Westendorf JJ, Badley AD. Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations. PLoS One 2011; 6 (9):e24876 Epub 2011 Sept 12
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  23. Rizza SA, Challagundla KB, Natesampillai S, Bren GD, Sykora J, Walczak H, Badley AD. TRAIL dependent fratricidal killing of gp120 primed hepatocytes by HCV core expressing hepatocytes. PLoS One 2011; 6 (11):e27171 Epub 2011 Nov 14
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  24. Natesampillai S, Nie Z, Cummins NW, Jochmans D, Bren GD, Angel JB, Badley AD. Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells. PLoS Pathog 2010 Nov 24; 6 (11):e1001213
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  25. Rizza SA, Cummins NW, Rider DN, Saeed S, Klein MB, Badley AD. Polymorphism in tumor necrosis factor-related apoptosis-inducing ligand receptor 1 is associated with poor viral response to interferon-based hepatitis C virus therapy in HIV/hepatitis C virus-coinfected individuals. AIDS 2010 Nov 13; 24 (17):2639-44
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  26. Cummins NW, Badley AD. Mechanisms of HIV-associated lymphocyte apoptosis: 2010. Cell Death Dis 2010 Nov 11; 1:e99
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  27. Cummins NW, Jiang W, McGinty J, Bren GD, Bosch RJ, Landay A, Deeks SG, Martin JN, Douek D, Lederman MM, Brenchley J, Badley AD. Intracellular Casp8p41 content is inversely associated with CD4 T cell count. J Infect Dis 2010 Aug 15; 202 (3):386-91
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  28. Trushin SA, Bren GD, Badley AD. CXCR4 Tropic HIV-1 gp120 Inhibition of SDF-1alpha-Induced Chemotaxis Requires Lck and is Associated with Cofilin Phosphorylation. Open Virol J 2010 Jun 23; 4:157-62 Epub 2010 June 23
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  29. Taylor JA, Cummins NW, Bren GD, Rizza SA, Kolbert CP, Behrens MD, Knutson KL, Kahl JC, Asmann YW, Badley AD. Casp8p41 expression in primary T cells induces a proinflammatory response. AIDS. 2010 Jun 1; 24(9):1251-8.
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  30. Singh VP, Bren GD, Algeciras-Schimnich A, Schnepple D, Navina S, Rizza SA, Dawra RK, Saluja AK, Chari ST, Vege SS, Badley AD. Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis. Am J Physiol Gastrointest Liver Physiol 2009 May; 296 (5):G1040-6 Epub 2009 Mar 12
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  31. Cummins N, Badley A. The TRAIL to viral pathogenesis: the good, the bad and the ugly. Curr Mol Med 2009 May; 9 (4):495-505
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  32. O'Hara SP, Small AJ, Gajdos GB, Badley AD, Chen XM, Larusso NF. HIV-1 Tat protein suppresses cholangiocyte toll-like receptor 4 expression and defense against Cryptosporidium parvum. J Infect Dis 2009 Apr 15; 199 (8):1195-204
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  33. Trushin SA, Bren GD, Badley AD. CD4 T Cells Treated with gp120 Acquire a CD45R0+/CD45RA+ Phenotype. Open Virol J 2009 Apr 01; 3:21-5
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  34. Shepard BD, Badley AD. The Biology of TRAIL and the Role of TRAIL-Based Therapeutics in Infectious Diseases. Antiinfect Agents Med Chem 2009 Apr 01; 8 (2):87-101
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  35. Babu CK, Suwansrinon K, Bren GD, Badley AD, Rizza SA. HIV induces TRAIL sensitivity in hepatocytes. PLoS One 2009; 4 (2):e4623 Epub 2009 Feb 27
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  36. Bren GD, Trushin SA, Whitman J, Shepard B, Badley AD. HIV gp120 induces, NF-kappaB dependent, HIV replication that requires procaspase 8. PLoS One 2009; 4 (3):e4875 Epub 2009 Mar 16
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  37. Shepard BD, De Forni D, McNamara DR, Foli A, Rizza SA, Abraham RS, Knutson K, Wettstein PJ, Lori F, Badley AD. Beneficial effect of TRAIL on HIV burden, without detectable immune consequences. PLoS One 2008 Aug 28; 3 (8):e3096
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  38. van de Beek D, Patel R, Campeau NG, Badley A, Parisi JE, Rabinstein AA, Manno EM, Wijdicks EF. Insidious sinusitis leading to catastrophic cerebral aspergillosis in transplant recipients. Neurology 2008 Jun 10; 70 (24 Pt 2):2411-3
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  39. Shepard BD, Loutfy MR, Raboud J, Mandy F, Kovacs CM, Diong C, Bergeron M, Govan V, Rizza SA, Angel JB, Badley AD. Early changes in T-cell activation predict antiretroviral success in salvage therapy of HIV infection. J Acquir Immune Defic Syndr 2008 Jun 01; 48 (2):149-55
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  40. Hisatomi T, Nakazawa T, Noda K, Almulki L, Miyahara S, Nakao S, Ito Y, She H, Kohno R, Michaud N, Ishibashi T, Hafezi-Moghadam A, Badley AD, Kroemer G, Miller JW. HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice. J Clin Invest. 2008 Jun; 118(6):2025-38.
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  41. Bren GD, Whitman J, Cummins N, Shepard B, Rizza SA, Trushin SA, Badley AD. Infected cell killing by HIV-1 protease promotes NF-kappaB dependent HIV-1 replication. PLoS One 2008 May 07; 3 (5):e2112
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  42. Rizza SR, Tangalos EG, McClees MD, Strausbauch MA, Targonski PV, McKean DJ, Wettstein PJ, Badley AD. Nelfinavir monotherapy increases naive T-cell numbers in HIV-negative healthy young adults. Front Biosci 2008 Jan 01; 13:1605-9
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  43. Rizza SA, Badley AD. HIV protease inhibitors impact on apoptosis. Med Chem 2008 Jan; 4 (1):75-9
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  44. Nie Z, Bren GD, Rizza SA, Badley AD. HIV Protease Cleavage of Procaspase 8 is Necessary for Death of HIV-Infected Cells. Open Virol J 2008; 2:1-7
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  45. Algeciras-Schimnich A, Belzacq-Casagrande AS, Bren GD, Nie Z, Taylor JA, Rizza SA, Brenner C, Badley AD. Analysis of HIV Protease Killing Through Caspase 8 Reveals a Novel Interaction Between Caspase 8 and Mitochondria. Open Virol J 2007 Dec 27; 1:39-46
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  46. Vlahakis SR, Bren GD, Algeciras-Schimnich A, Trushin SA, Schnepple DJ, Badley AD. Flying in the face of resistance: antiviral-independent benefit of HIV protease inhibitors on T-cell survival. Clin Pharmacol Ther. 2007 Sep; 82(3):294-9. Epub 2007 Mar 14.
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  47. Nie Z, Bren GD, Vlahakis SR, Schimnich AA, Brenchley JM, Trushin SA, Warren S, Schnepple DJ, Kovacs CM, Loutfy MR, Douek DC, Badley AD. Human immunodeficiency virus type 1 protease cleaves procaspase 8 in vivo. J Virol 2007 Jul; 81 (13):6947-56 Epub 2007 Apr 18
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  48. Tracz MJ, Juncos JP, Grande JP, Croatt AJ, Ackerman AW, Rajagopalan G, Knutson KL, Badley AD, Griffin MD, Alam J, Nath KA. Renal hemodynamic, inflammatory, and apoptotic responses to lipopolysaccharide in HO-1-/- mice. Am J Pathol 2007 Jun; 170 (6):1820-30
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  49. Vlahakis SR, Bennett SA, Whitehead SN, Badley AD. HIV protease inhibitors modulate apoptosis signaling in vitro and in vivo. Apoptosis. 2007 May; 12(5):969-77.
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  50. Trushin SA, Algeciras-Schimnich A, Vlahakis SR, Bren GD, Warren S, Schnepple DJ, Badley AD. Glycoprotein 120 binding to CXCR4 causes p38-dependent primary T cell death that is facilitated by, but does not require cell-associated CD4. J Immunol. 2007 Apr 15; 178(8):4846-53.
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  51. O'Hara SP, Small AJ, Nelson JB, Badley AD, Chen XM, Gores GJ, Larusso NF. The human immunodeficiency virus type 1 tat protein enhances Cryptosporidium parvum-induced apoptosis in cholangiocytes via a Fas ligand-dependent mechanism. Infect Immun 2007 Feb; 75 (2):684-96 Epub 2006 Nov 21
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  52. Murali NS, Ackerman AW, Croatt AJ, Cheng J, Grande JP, Sutor SL, Bram RJ, Bren GD, Badley AD, Alam J, Nath KA. Renal upregulation of HO-1 reduces albumin-driven MCP-1 production: implications for chronic kidney disease. Am J Physiol Renal Physiol 2007 Feb; 292 (2):F837-44 Epub 2006 Sept 12
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  53. Assi MA, Binnicker MJ, Wengenack NL, Deziel PJ, Badley AD. Disseminated coccidioidomycosis in a liver transplant recipient with negative serology: use of polymerase chain reaction. Liver Transpl 2006 Aug; 12 (8):1290-2
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  54. Chui C, Cheung PK, Brumme CJ, Mo T, Brumme ZL, Montaner JS, Badley AD, Harrigan PR. HIV VprR77Q mutation does not influence clinical response of individuals initiating highly active antiretroviral therapy. AIDS Res Hum Retroviruses. 2006 Jul; 22(7):615-8.
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  55. Vlahakis SR, Badley AD. Influence of proteasome inhibitors on apoptosis. Curr Opin Clin Nutr Metab Care. 2006 Jan; 9(1):42-7.
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  56. Graham DB, Bell MP, Huntoon CJ, Weaver JGR, Hawley N, Badley AD, McKean DJ. Increased thymic output in HIV-negative patients after antiretroviral therapy. AIDS. 2005 Sep 23; 19(14):1467-72.
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  57. Trushin SA, Bren GD, Asin S, Pennington KN, Paya CV, Badley AD. Human immunodeficiency virus reactivation by phorbol esters or T-cell receptor ligation requires both PKCalpha and PKCtheta. J Virol. 2005 Aug; 79(15):9821-30.
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  58. Pittock ST, Norby SM, Grande JP, Croatt AJ, Bren GD, Badley AD, Caplice NM, Griffin MD, Nath KA. MCP-1 is up-regulated in unstressed and stressed HO-1 knockout mice: Pathophysiologic correlates. Kidney Int 2005 Aug; 68 (2):611-22
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  59. Badley AD. In vitro and in vivo effects of HIV protease inhibitors on apoptosis. Cell Death Differ. 2005 Aug; 12 Suppl 1:924-31.
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  60. Lum JJ, Schnepple DJ, Badley AD. Acquired T-cell sensitivity to TRAIL mediated killing during HIV infection is regulated by CXCR4-gp120 interactions. AIDS. 2005 Jul 22; 19(11):1125-33.
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  61. Lum JJ, Bren G, McClure R, Badley AD. Elimination of senescent neutrophils by TNF-related apoptosis-inducing [corrected] ligand. J Immunol. 2005 Jul 15; 175(2):1232-8.
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  62. Weaver JGR, Tarze A, Moffat TC, LeBras M, Deniaud A, Brenner C, Bren GD, Morin MY, Phenix BN, Dong L, Jiang SX, Sim VL, Zurakowski B, Lallier J, Hardin H, Wettstein P, van Heeswijk RPG, Douen A, Kroemer RT, Hou ST, Bennett SAL, Lynch DH, Kroemer G, Badley AD. Badley AD. Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor. J Clin Invest. 2005 Jul; 115(7):1828-38.
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  63. Weaver JG, McGregor CG, Tazelaar HD, Badley AD. Rejection severity directly correlates with myocyte apoptosis in pig-to-baboon cardiac xenotransplantation. J Heart Lung Transplant 2005 Jul; 24 (7):841-7
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  64. Anson BD, Weaver JGR, Ackerman MJ, Akinsete O, Henry K, January CT, Badley AD. Blockade of HERG channels by HIV protease inhibitors. Lancet. 2005 Feb 19; 365(9460):682-6.
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  65. Cuerrier D, Nie Z, Badley AD, Davies PL. Ritonavir does not inhibit calpain in vitro. Biochemical & Biophysical Research Communications. 2005 Feb 4; 327(1):208-11.
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  66. Weaver JGR, Rouse MS, Steckelberg JM, Badley AD. Improved survival in experimental sepsis with an orally administered inhibitor of apoptosis. FASEB J. 2004 Aug; 18(11):1185-91.
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  67. Buenz EJ, Badley AD. Impact of mitochondrial regulation of apoptosis on the pathogenesis and treatment of HIV-1-induced immunodeficiency. Mitochondrion. 2004 Jul; 4(2-3):235-54.
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  68. Lum JJ, Schnepple DJ, Nie Z, Sanchez-Dardon J, Mbisa GL, Mihowich J, Hawley N, Narayan S, Kim JE, Lynch DH, Badley AD. Differential effects of interleukin-7 and interleukin-15 on NK cell anti-human immunodeficiency virus activity. J Virol 2004 Jun; 78 (11):6033-42
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  69. Zhang XP, Lalezari JP, Badley AD, Dorr A, Kolis SJ, Kinchelow T, Patel IH. Assessment of drug-drug interaction potential of enfuvirtide in human immunodeficiency virus type 1-infected patients. Clinical Pharmacology & Therapeutics. 2004 Jun; 75(6):558-68.
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  70. Owen C, Kazim F, Badley AD. Effect on CD4 T-cell count of replacing protease inhibitors in patients with successful HIV suppression: a meta-analysis. AIDS. 2004 Mar 5; 18(4):693-5.
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  71. Cohen I, Boya P, Zhao L, Metivier D, Andreau K, Perfettini JL, Weaver JG, Badley A, Taylor EW, Kroemer G. Anti-apoptotic activity of the glutathione peroxidase homologue encoded by HIV-1. Apoptosis. 2004 Mar; 9(2):181-92.
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  72. Cooper CL, Phenix B, Mbisa G, Lum JJ, Parato K, Hawley N, Angel JB, Badley AD. Antiretroviral therapy influences cellular susceptibility to apoptosis in vivo. Front Biosci. 2004 Jan; 9:338-41.
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  73. Buenz EJ, Weaver JG, Bauer BA, Chalpin SD, Badley AD. Cordyceps sinensis extracts do not prevent Fas-receptor and hydrogen peroxide-induced T-cell apoptosis. J Ethnopharmacol. 2004 Jan; 90(1):57-62.
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  74. Lum JJ, Badley AD. Resistance to apoptosis: Mechanism for the development of HIV reservoirs. Current HIV Research. 2003 Jul; 1(3):261-74.
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  75. Badley AD, Roumier T, Lum JJ, Kroemer G. Mitochondrion-mediated apoptosis in HIV-1 infection. Trends Pharmacol Sci. 2003 Jun; 24(6):298-305.
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  76. Jiang JQ, Balasubramanian S, Hawley-Foss NC, Badley AD, Rosenthal KL, Copeland KF. Production of CD8+ T cell nonlytic suppressive factors by CD28, CD38, and HLA-DR subpopulations. AIDS Res Hum Retroviruses. 2003 Jun; 19(6):497-502.
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  77. Lum JJ, Cohen OJ, Nie ZL, Weaver JG, Gomez TS, Yao XJ, Lynch D, Pilon AA, Hawley N, Kim JE, Chen ZX, Montpetit M, Sanchez-Dardon J, Cohen EA, Badley AD. Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis. J Clin Invest. 2003 May; 111(10):1547-54.
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  78. Narayan S, Hawley N, Giguere P, Badley AD. Attenuated T-lymphocyte response to HIV therapy in individuals receiving HMG-CoA reductase inhibitors. HIV Clinical Trials. 2003 May-Jun; 4(3):164-9.
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  79. Nie Z, Phenix BN, Lum JJ, Alam A, Lynch DH, Beckett B, Krammer PH, Sekaly RP, Badley AD. HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation. Cell Death & Differentiation. 2002 Nov; 9(11):1172-84.
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  80. Phenix BN, Cooper C, Owen C, Badley AD. Modulation of apoptosis by HIV protease inhibitors. Apoptosis. 2002 Aug; 7(4):295-312.
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  81. Pilon AA, Lum JJ, Sanchez-Dardon J, Phenix BN, Douglas R, Badley AD. Induction of apoptosis by a nonnucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitor. Antimicrobial Agents & Chemotherapy. 2002 Aug; 46(8):2687-91.
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  82. Walmsley S, Bernstein B, King M, Arribas J, Beall G, Ruane P, Johnson M, Johnson D, Lalonde R, Japour A, Brun S, Sun E. Lopinavir-ritonavir versus nelfinavir for the initial treatment of HIV infection. N Engl J Med. 2002 Jun 27; 346(26):2039-46.
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  83. Phenix BN, Badley AD. Influence of mitochondrial control of apoptosis on the pathogenesis, complications and treatment of HIV infection. Biochimie. 2002 Feb; 84(2-3):251-64.
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  84. Mikhael J, Humphrey S, Jabi M, Badley AD. Atypical cause of pulmonary infiltrate in a typical patient. Can J Infect Dis. 2002; 13:71-2.
  85. Hawley-Foss N, Mbisa G, Lum JJ, Pilon AA, Angel JB, Garber G, Badley AD. Effect of therapy cessation during a discordant response to highly active antiretroviral therapy: implications for scheduled therapeutic interruptions. Clin Infect Dis. 2002; 34:553-6.
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  86. Parato KG, Kumar A, Badley AD, Sanchez-Dardon J, Chambers KA, Young CD, Lim WT, Kravcik S, Cameron DW, Angel JB. Normalization of natural killer cell function and phenotype with effective anti-HIV therapy and the role of interleukin-10. AIDS. 2002; 16(9):1251-6.
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  87. Bergeron R, Nicholson JKA, Phaneuf S, Ding T, Soucy N, Badley A, Hawley-Foss NC, Mandy F. Selection of lymphocyte gating protocol has an impact on the level of reliability of T-cell subsets in aging specimens. Cytometry. 2002; 50(2):53-61.
  88. Lum JJ, Pilon AA, Sanchez-Dardon J, Phenix BN, Kim JE, Mihowich J, Jamison K, Hawley-Foss N, Lynch DH, Badley AD. Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l. J Virol. 2001 Nov; 75(22):11128-36.
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  89. Teixeira L, Valdez H, McCune JM, Koup RA, Badley AD, Hellerstein MK, Napolitano LA, Douek DC, Mbisa G, Deeks S, Harris JM, Barbour JD, Gross BH, Francis IR, Halvorsen R, Asaad R, Lederman MM. Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function. AIDS. 2001 Sep 28; 15(14):1749-56.
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  90. Phenix BN, Lum JJ, Nie Z, Sanchez-Dardon J, Badley AD. Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss. Blood. 2001 Aug 15; 98(4):1078-85.
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  91. Hawley-Foss N, Mbisa G, Lum JJ, Pilon AA, Angel JB, Garber G, Badley AD. Effect of cessation of highly active antiretroviral therapy during a discordant response: implications for scheduled therapeutic interruptions. Clin Infect Dis. 2001 Aug 1; 33(3):344-8. Epub 2001 Jun 21.
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  92. Maslove DM, Ni LW, Hawley-Foss NC, Badley AD, Copeland KF. Modulation of HIV transcription by CD8(+) cells is mediated via multiple elements of the long terminal repeat. Clin Exp Immunol. 2001 Jul; 125(1):102-9.
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  93. Cooper CL, Badley AD, Angel JB. Characteristics of hepatitis C virus infection in HIV-infected people. Can J Infect Dis. 2001 May; 12(3):157-63.
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  94. Kravcik S, Magill A, Sanghvi B, Ogden R, Cameron WD, Lewis R, Yu G, Badley AD. Comparative CD4 T-cell responses of reverse transcriptase inhibitor therapy with or without nelfinavir matched for viral exposure. HIV Clin Trials. 2001 Mar-Apr; 2(2):160-70.
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  95. Angel JB, Parato KG, Kumar A, Kravcik S, Badley AD, Fex C, Ashby D, Sun E, Cameron WD. Progressive human immunodeficiency virus specific immune recovery with prolonged viral suppression. J Inf Dis. 2001; 183:546-54.
  96. Giguere P, Badley AD. Issues concerning therapy with HIV protease inhibitors. Clinical Perspectives in HIV Therapy. The Medicine Group Ltd. 2001:1-18.
  97. Kim WR, Badley AD, Wiesner RH, Porayko MK, Seaberg EC, Keating MR, Evans RW, Dickson ER, Krom RA, Paya CV. The economic impact of cytomegalovirus infection after liver transplantation. Transplantation. 2000 Feb 15; 69(3):357-61.
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  98. Phenix BN, Angel J, Mandy F, Parato K, Chambers KA, Kravcik S, Hawley-Foss N, Cassol S, Cameron DW, Badley AD. Decreased HIV associated T cell apoptosis by HIV protease inhibitors. AIDS Res & Hum Retro. 2000; 6:559-67.
  99. Badley AD, Pilon AA, Landay A, Lynch DH. Mechanisms of HIV associated lymphocyte apoptosis. Blood. 2000; 96:2951-64.
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  100. Lauzon W, Sanchez Dardon J, Cameron DW, Badley AD. Flow cytometric measurement of telomere length. Cytometry. 2000; 42:159-64.
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  101. Khaliq Y, Gallicano K, Seguin I, Fyke K, Carignan G, Bulman D, Badley A, Cameron DW. Single and multiple dose pharmacokinetics of nelfinavir and CYP2C19 activity in human immunodeficiency virus-infected patients with chronic liver disease. Br J Clin Pharmacol. 2000; 50:108-15.
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  102. Khaliq Y, Gallicano K, Leger R, Foster B, Badley A. A drug interaction between fusidic acid and a combination of ritonavir and saquinavir. Br J Clin Pharmacol. 2000; 50:81-3.
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  103. Dockrell DH, Badley AD, Algeciras-Schimnich A, Simpson M, Schut R, Lynch DH, Paya CV. Activation-induced CD4+ T cell death in HIV-positive individuals correlates with Fas susceptibility, CD4+ T cell count, and HIV plasma viral copy number. AIDS Res Hum Retroviruses. 1999 Nov 20; 15(17):1509-18.
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  104. Badley AD, Parato K, Cameron DW, Kravcik S, Phenix BN, Ashby D, Kumar A, Lynch DH, Tschopp J, Angel JB. Dynamic correlation of apoptosis and Immune activation during treatment of HIV infection. Cell Death and Differentiation. 1999; 6:420-32.
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  105. Hunt RH, Fallone CA, Badley AD, Thomson ABR. For the Canadian Helicobacter Study Group (CHSG). Update to the Canadian Consensus Conference on Helicobacter pylori infections in adults Can J Gastroenterol. 1999; 13:213-7.
  106. Kravcik S, Gallicano K, Roth V, Cassol S, Hawley-Foss N, Badley A, Cameron DW. Cerebrospinal fluid HIV RNA and drug levels with combination ritonavir and saquinavir. JAIDS. 1999; 21:371-5.
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  107. Kravcik S, Victor G, Angel JB, Badley AD, Garber GE, Cameron DW. Activity of the combination of nelfinavir and saquinavir against human immunodeficiency virus after failure of prior protease inhibitor therapy. Clin Inf Dis. 1999; 29:702-3.
  108. Falagas ME, Paya C, Ruthazer R, Badley A, Patel R, Wiesner R, Griffith J, Freeman R, Rohrer R, Werner BG, Snydman DR. Significance of cytomegalovirus for long-term survival after orthotopic liver transplantation: a prospective derivation and validation cohort analysis. Transplantation. 1998 Oct 27; 66(8):1020-8.
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  109. O'Connor WJ, Badley AD, Dicken CH, Murphy GM. Porphyria cutanea tarda and human immunodeficiency virus: two cases associated with hepatitis C. Mayo Clin Proc. 1998 Sep; 73(9):895-7.
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  110. Badley AD, Dockrell DH, Algeciras A, Ziesmer S, Landay A, Lederman MM, Connick E, Kessler H, Kuritzkes D, Lynch DH, Roche P, Yagita H, Paya CV. In vivo analysis of Fas/FasL interactions in HIV-infected patients. J Clin Invest. 1998 Jul 1; 102(1):79-87.
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  111. Dockrell DH, Badley AD, Villacian JS, Heppelmann CJ, Algeciras A, Ziesmer S, Yagita H, Lynch DH, Roche PC, Leibson PJ, Paya CV. The expression of Fas Ligand by macrophages and its upregulation by human immunodeficiency virus infection. J Clin Invest. 1998 Jun 1; 101(11):2394-405.
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  112. Holtz-Heppelmann CJ, Algeciras A, Badley AD, Paya CV. Transcriptional regulation of the human FasL promoter-enhancer region. J Biol Chem. 1998 Feb 20; 273(8):4416-23.
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  113. Dockrell DH, Prada J, Jones MF, Patel R, Badley AD, Harmsen WS, Ilstrup DM, Wiesner RH, Krom RA, Smith TF, Paya CV. Seroconversion to human herpesvirus 6 following liver transplantation is a marker of cytomegalovirus disease. J Infect Dis. 1997 Nov; 176(5):1135-40.
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  114. Badley AD, Seaberg EC, Porayko MK, Wiesner RH, Keating MR, Wilhelm MP, Walker RC, Patel R, Marshall WF, DeBernardi M, Zetterman R, Steers JL, Paya CV. Prophylaxis of cytomegalovirus infection in liver transplantation: a randomized trial comparing a combination of ganciclovir and acyclovir to acyclovir. NIDDK Liver Transplantation Database. Transplantation. 1997 Jul 15; 64(1):66-73.
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  115. Badley AD, Dockrell D, Simpson M, Schut R, Lynch DH, Leibson P, Paya CV. Macrophage-dependent apoptosis of CD4+ T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor. J Exp Med. 1997 Jan 6; 185(1):55-64.
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  116. Badley AD, Dockrell D, Paya CV. Apoptosis in AIDS. Adv Pharmacol. 1997; 41:271-94.
  117. Das M, Badley AD, Cockerill FR, Steckelberg JM, Wilson WR. Infective endocarditis caused by HACEK microorganisms. Annu Rev Med. 1997; 48:25-33.
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  118. Patel R, Portela D, Badley AD, Harmsen WS, Larson-Keller JJ, Ilstrup DM, Keating MR, Wiesner RH, Krom RA, Paya CV. Risk factors of invasive Candida and non-Candida fungal infections after liver transplantation. Transplantation. 1996 Oct 15; 62(7):926-34.
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  119. Badley AD, Steckelberg JM, Wollan PC, Thompson RL. Infectious rates of central venous pressure catheters: comparison between newly placed catheters and those that have been changed. Mayo Clin Proc. 1996 Sep; 71(9):838-46.
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  120. Badley AD, Portela DF, Patel R, Kyle RA, Habermann TM, Strickler JG, Ilstrup DM, Wiesner RH, de Groen P, Walker RC, Paya CV. Development of monoclonal gammopathy precedes the development of Epstein-Barr virus-induced posttransplant lymphoproliferative disorder. Liver Transpl Surg. 1996 Sep; 2(5):375-82.
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  121. Badley AD, van Scoy RE. Long-term follow-up of multifocal osteoarticular sporotrichosis treated with itraconazole. Clin Infect Dis. 1996 Aug; 23(2):394-5.
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  122. Patel R, Badley AD, Larson-Keller J, Harmsen WS, Ilstrup DM, Wiesner RH, Steers JL, Krom RA, Portela D, Cockerill FR, Paya CV. Relevance and risk factors of enterococcal bacteremia following liver transplantation. Transplantation. 1996 Apr 27; 61(8):1192-7.
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  123. Badley AD, Patel R, Portela DF, Harmsen WS, Smith TF, Ilstrup DM, Steers JL, Wiesner RH, Paya CV. Prognostic significance and risk factors of untreated cytomegalovirus viremia in liver transplant recipients. J Infect Dis. 1996 Feb; 173(2):446-9.
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  124. Badley AD, McElhinny JA, Leibson PJ, Lynch DH, Alderson MR, Paya CV. Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes. J Virol. 1996 Jan; 70(1):199-206.
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  125. Lynch DH, Campbell KA, Miller RE, Badley AD, Paya CV. FasL/Fas and TNF/TNFR interactions in the regulation of immune responses and disease Behring Inst Mitt , 1996; 97:1-10.
  126. MacMorran WS, Badley AD, Wilson WR. 26-year-old man with HIV infection and abdominal pain. Mayo Clin Proc. 1995 Sep; 70(9):885-8.
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  127. Badley AD, Camilleri M, O'Connor MK. Noninvasive measurement of human ascending colon volume. Nucl Med Commun 1993 Jun; 14 (6):485-9
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  128. Schlech W, Chase DP, Badley AD. A model of food-borne Listeria monocytogenes infection in the Sprague Dauley rat using gastric innoculation; development and effect of gastric acidity on infective dose. Int J Food Microbiology. 1993; 18(1):15-24.
  129. Badley AD, MacCormick RE, LeBrun GP. Neoplastic imitators of small bowel Crohn's disease. Can J Gastroenterol. 1992; 6(2):77-83.
  130. Badley AD, Phillips B, Haldane D, Dalton M. Pathogenic marine Vibrio species in selected Nova Scotian recreational coastal waters. Can J Pub Health. 1990; 81:263-7.