Publications

  1. Zachariah PK. Improving patient education through technology. Group Practice Journal. 2005 Jul-Aug; 54(7):27-31.
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  2. Ejaz AA, Fitzpatrick PM, Haley WE, Wasiluk A, Durkin AJ, Zachariah PK. Amlodipine besylate induced acute interstitial nephritis. Nephron. 2000 Aug; 85(4):354-6.
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  3. Papademetriou V, Gottdiener JS, Narayan P, Cushman WG, Zachariah PK, Gottdiener PS, Chase GA. Hydrochlorothiazide is superior to isradipine for reduction of left ventricular mass - results of a multicenter trial. J Am Coll Cardiol. 1997 Dec; 30(7):1802-1808.
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  4. Staessen JA, Zachariah PK, et al. Nocturnal blood pressure fall on ambulatory monitoring in a large international database. Hypertension. 1997; 29:30-9.
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  5. Lutgarde T, Zachariah PK, Weizhong Z. Ambulatory blood pressure in normotensive and hypertensive subjects: results from an international database. Neth J Med. 1995; 46:106-114.
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  6. Sheps SG, Bailey KR, Zachariah PK. Short-term (six hour), ambulatory blood pressure monitoring. J Hum Hypertens. 1994 Dec; 8(12):873-8.
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  7. Clements IP, Bailey KR, Zachariah PK. Effects of exercise and therapy on ventricular emptying and filling in mildly hypertensive patients. Am J Hypertens. 1994 Aug; 7(8):695-702.
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  8. Thijs L, Staessen J, Fagard R, Zachariah P, Amery A. Number of measurements required for the analysis of diurnal blood pressure profile. J Hum Hypertens. 1994 Apr; 8(4):239-44.
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  9. Shub C, Klein AL, Zachariah PK, Bailey KR, Tajik AJ. Determination of left ventricular mass by echocardiography in a normal population: effect of age and sex in addition to body size. Mayo Clin Proc. 1994 Mar; 69(3):205-11.
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  10. Klein AL, Burstow DJ, Tajik AJ, Zachariah PK, Bailey KR, Seward JB. Effects of age on left ventricular dimensions and filling dynamics in 117 normal persons. Mayo Clin Proc. 1994 Mar; 69(3):212-24.
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  11. Zachariah PK, White WB. Reliability and practical value of automated blood pressure monitoring. Cardiovasc Rev Rep. 1994; 16(3):8-20.
  12. Staessen JA, O'Brien ET, Amery AK, Atkins N, Baumgart P, De Cort P, Degaute JP, Dolenc P, De Gaudemaris R, Enstrom I, Fagard R, Gosse P, Gourlay S, Hayashi H, Imai Y, James G, Kawasaki T, Kuschnir E, Kuwajima I, Lindholm L, Liu L, Macor F, Mancia G, Ambulatory blood pressure in normotensive and hypertensive subjects: results from an international database. J Hypertens. 1994; 12(Suppl):S1-S12.
  13. Zachariah PK, Messerli FH, Mroczek W. Low-dose bisoprolol/hydrochlorothiazide: an option in first-line, antihypertensive treatment. Clin Ther. 1993 Sep-Oct; 15(5):779-87.
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  14. Zachariah PK, Sumner WE 3rd. The clinical utility of blood pressure load in hypertension. Am J Hypertens. 1993 Jun; 6(6 Pt 2):194S-197S.
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  15. Staessen J, O'Brien E, Atkins N, Amery A, Zachariah PK, et al. The ambulatory pressure in normotensive compared with hypertensive subjects. J Hypertens. 1993; 11:1189-97.
  16. Zachariah PK. The role of ambulatory blood pressure monitoring in research. Clin Cardiol. 1992 Oct; 15(Suppl):II-6-II-9.
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  17. Zachariah PK, Krier J, Schwartz GL. Orthostatic hypotension and ambulatory blood pressure monitoring. J Hypertens Suppl. 1991 Dec; 9(8):S78-80.
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  18. Zachariah PK, Krier JD. Hypertension and ambulatory blood pressure monitoring. Prim Care. 1991 Sep; 18(3):651-62.
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  19. Zachariah PK, Sheps SG, Bailey KR, Wiltgen CM, Moore AG. Age-related characteristics of ambulatory blood pressure load and mean blood pressure in normotensive subjects. JAMA. 1991 Mar 20; 265(11):1414-7.
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  20. Zachariah PK, Krier JD. Clinical uses of ambulatory blood pressure monitoring. J Hypertens Suppl. 1991 Jan; 9(1):S7-11; discussion S11-2.
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  21. Zachariah PK, Moyer TP, Theobald HM, Frantz RP, Kurtz SB, McCarthy JT, Smith RL. The pharmacokinetics of racemic verapamil in patients with impaired renal function. J Clin Pharmacol. 1991 Jan; 31(1):45-53.
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  22. Zachariah PK, Krier JD. Effects of circadian variations on cardiovascular events and treatment of hypertension. Fam Pract Recertif. 1991; 13:28-33.
  23. Zachariah PK, Sheps SG, Bailey KR, Wiltgen CM, Moore AG. Reproducibility of ambulatory blood pressure load. J Hum Hypertens. 1990 Dec; 4(6):625-31.
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  24. Zachariah PK, Schwartz GL, Sheps SG, Schirger A, Carlson CA, Moore AG. Antihypertensive effects of a new sustained-release formulation of nifedipine. J Clin Pharmacol. 1990 Nov; 30(11):1012-9.
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  25. Sheps SG, et al. National high blood pressure education program working group report on ambulatory blood pressure monitoring. (The National High Blood Pressure Education Coordinating Committee. S. G. Ships, MD.- Working group chairman). Arch Intern Med. 1990 Nov; 150:2270-2280.
  26. Zachariah PK, Sheps SG, Moore AG. Office blood pressures in supine, sitting, and standing positions: correlation with ambulatory blood pressures. Int J Cardiol. 1990 Sep; 28(3):353-60.
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  27. Ritter SG, Bentley MD, Fiksen-Olsen MJ, Brown ML, Romero JC, Zachariah PK. Effect of captopril on renal function in hypertensive dogs with unilateral renal artery stenosis, studied with radionuclide dynamic scintigraphy. Am J Hypertens. 1990 Aug; 3(8 Pt 1):591-8.
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  28. Klein AL, Burstow DJ, Tajik AJ, Zachariah PK, Taliercio CP, Taylor CL, Bailey KR, Seward JB. Age-related prevalence of valvular regurgitation in normal subjects: a comprehensive color flow examination of 118 volunteers. J Am Soc Echocardiogr. 1990 Jan-Feb; 3(1):54-63.
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  29. Zachariah PK, Cornelissen G, Halberg F. Ambulatory cardiovascular monitoring of healthy adults in Rochester, Minnesota: chronobiologic assessment. Progress in Clinical & Biological Research. 1990; (341A):243-54.
  30. Shepherd RF, Zachariah PK, Shub C. Hypertension and left ventricular diastolic function. Mayo Clin Proc. 1989 Dec; 64(12):1521-32.
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  31. Zachariah PK, Sheps SG, Smith RL. Clinical use of home and ambulatory blood pressure monitoring. Mayo Clin Proc. 1989 Nov; 64(11):1436-46.
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  32. Zachariah PK. Hypertension--an overview. Mayo Clin Proc. 1989 Nov; 64(11):1403-5.
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  33. Halberg F, Cornelissen G, Jinyi W, Zachariah PK. Chronopharmacologic individualized and group assessment of outcomes in antihypertensive drug trials. Proceedings 2nd Annual IEEE (Institute Electrical and Electronic Engineers) Symposium on Computer-based Medical System. 1989; 253.
  34. Zachariah P, Ritter S, Fiksen-Olsen M, Strong C, Romero JC. Stimulation of plasma renin activity by captopril in renovascular hypertensive conscious dogs. Clin Exp Hypertens A. 1989; 11(2):205-13.
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  35. Zachariah PK, Sheps SG, Ilstrup DM, Long CR, Bailey KR, Wiltgen CM, Carlson CA. Blood pressure load--a better determinant of hypertension. Mayo Clin Proc. 1988 Nov; 63(11):1085-91.
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  36. Zachariah PK, Shub C, Sheps SG, Schirger A, Wolf MK, Carlson CA. Correlation between verapamil plasma concentration and P-R prolongation in essential hypertension. J Clin Pharmacol. 1988 Sep; 28(9):843-7.
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  37. Zachariah PK, Sheps SG, Schwartz GL, Schirger A, Ilstrup DM, Long CR, Carlson CA. Antihypertensive efficacy of lisinopril. Ambulatory blood pressure monitoring. Am J Hypertens. 1988 Jul; 1(3 Pt 3):274S-279S.
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  38. Zachariah PK, Schwartz GL, Strong CG, Ritter SG. Parathyroid hormone and calcium. A relationship in hypertension. Am J Hypertens. 1988 Jul; 1(3 Pt 3):79S-82S.
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  39. Zachariah PK, Brobyn R, Kann J, Levy B, Margolis R, McMahon FG, Reeves R, Sperling DC, Sweet D, Zager P, et al. Comparison of quality of life on nitrendipine and propranolol. J Cardiovasc Pharmacol. 1988; 12 Suppl 4:S29-35.
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  40. Zachariah PK, Sheps SG, Smith RL. Defining the roles of home and ambulatory monitoring. Diagnosis. 1988; 10:39.
  41. Zachariah PK, Sheps SG, Smith RL. Role of self-monitoring and ambulatory monitoring in diagnosis and evaluation of hypertension. Pract Cardiol. 1988; 14:79.
  42. Zachariah PK, Sheps SG, Oshrain C, Schirger A, Stein WJ. Antihypertensive efficacy of sustained-release verapamil. J Clin Hypertens. 1987 Dec; 3(4):536-46.
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  43. Zachariah PK. Quality of life with antihypertensive medication. J Hypertens Suppl. 1987 Dec; 5(4):S105-10.
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  44. Zachariah PK. Nitrendipine as an antihypertensive agent. Eur Heart J. 1987 Nov; 8 Suppl K:63-7.
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  45. Zachariah PK, Burnett JC Jr, Ritter SG, Strong CG. Atrial natriuretic peptide in human essential hypertension. Mayo Clin Proc. 1987 Sep; 62(9):782-6.
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  46. Shub C, Zachariah PK, Ilstrup DM, Tajik AJ. Effects of pinacidil on the heart: serial electrocardiographic and echocardiographic observations. Can J Cardiol. 1987 Jun-Aug; 3(5):223-9.
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  47. Sheps SG, Schirger A, Zachariah PK, Fisher LD, Spiekerman RE, Araas FJ, Collins JB, Agerter DC. Comparison of ketanserin and metoprolol in the treatment of essential hypertension. Arch Intern Med. 1987 Feb; 147(2):291-6.
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  48. Zachariah PK, Schwartz GL, Ritter SG, Strong CG. Plasma predictors of calcium channel blocker efficacy in hypertension. J Cardiovasc Pharmacol. 1987; 9:S148.
  49. Zachariah PK, Bonnet G, Chrysant SG, DeBacker G, Goldstein R, Herrera J, Lindner A, Materson BJ, Maxwell MH, McMahon FG. Evaluation of antihypertensive efficacy of lisinopril compared to metoprolol in moderate to severe hypertension. J Cardiovasc Pharmacol. 1987; 9(Suppl 3):S53-8.
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  50. Laragh JH, Buhler FR, Chobanian A, Hansson L, Zachariah PK. Calcium antagonists in hypertension: update 1986. J Cardiovasc Pharmacol. 1987; 9(Suppl 4, Pt. 1):S1-S3.
  51. Zachariah PK, Sheps SG, Schwartz GL, Ilstrup DM, Schirger A, Ritter SG. Continuous blood pressure monitoring--nitrendipine antihypertensive response. J Cardiovasc Pharmacol. 1987; 9(Suppl 4, Pt. 1):S154-S160.
  52. McMahon FG, Brobyn R, Kann J, Levy B, Margolis R, Reeves R, Sklar J, Sweet D, Zachariah PK, et al. A double blind comparative study of nitrendipine and propranolol in the treatment of hypertension. J Cardiovasc Pharmacol. 1987; 9:S228.
  53. Swanson KT, Shub C, Zachariah PK. Significance of electrocardiographic ST-T wave abnormalities in patients with mild-to-moderate hypertension: clinical-- echocardiographic correlates. J Hypertens. 1986 Dec; 4(Suppl 5):S313-S315.
  54. Zachariah PK, Sheps SG, Schriger A. Efficacy of sustained-release verapamil: automatic ambulatory blood pressure monitoring. J Clin Hypertens. 1986 Sep; 2(3 Suppl):133S-142S.
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  55. Zachariah PK, Bloedow DC, Moyer TP, Sheps SG, Schirger A, Fealey RD. Pharmacodynamics of midodrine, an antihypotensive agent. Clinical Pharmacology & Therapeutics. 1986 May; 39(5):586-91.
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  56. Zachariah PK, Sheps SG, Schirger A, Spiekerman RE, O'Brien PC, Simpson KK. Verapamil and 24-hour ambulatory blood pressure monitoring in essential hypertension. Am J Cardiol. 1986 Feb 26; 57(7):74D-79D.
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  57. Zachariah PK, Sheps SG, Schirger A, Fisher LD, Shub C, Collins JB, Spiekerman RE. Antihypertensive efficacy of pinacidil--automatic ambulatory blood pressure monitoring. Eur J Clin Pharmacol. 1986; 31(2):133-41.
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  58. Zachariah PK, Rosenbaum AH. Stabilization of high blood pressure with tricyclic antidepressants and lithium combinations in hypertensive patients. Mayo Clin Proc. 1982 Oct; 57(10):625-8.
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  59. Fernandez PG, Sharma JN, Galway AB, Kim BK, Granter S, Zachariah PK. Comparison of antihypertensive efficacy: propranolol versus oxprenolol in accelerated hypertension. Pharmatherapeutica. 1982; 3(3):153-6.
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  60. Fernandez PG, Zachariah PK, Bryant DG, Missan SS. Antihypertensive efficacy of alpha-methyldopa, chlorothiazide and Supres-150 (alpha-methyldopa-chlorothiazide). CMAJ: Canadian Medical Association Journal. 1980 Aug 23; 123(4):284-7.
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  61. Fernandez PG, Zachariah PK, Gault MH, Bryant DG. Peripheral renin activity before and after furosemide in normotensives and hypertensives. Clinical & Investigative Medicine - Medecine Clinique et Experimentale. 1980; 3(3-4):253-8.
  62. Rahimtula AD, Zachariah PK, O'Brien PJ. Differential effects of antioxidants, steroids and other compounds on benzo(a)pyrene 3-hydroxylase activity in various tissues of rat. Br J Cancer. 1979 Jul; 40(1):105-12.
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  63. Rahimtula AD, O'Brien PJ, Zachariah PK. Effect of antioxidants on human placental aryl hydrocarbon hydroxylase. Cancer Biochem Biophys. 1979; 4(1):9-11.
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  64. Fernandez PG, Day JH, Simpson NE, Zachariah PK. Hereditary angioneurotic edema and Charcot-Marie-Tooth disease in the same family. CMAJ: Canadian Medical Association Journal. 1978 Sep 9; 119(5):455-8.
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  65. Martinsen CS, Zachariah PK. Growth of various bacteria on polycyclic aromatic hydrocarbons and N-2-fluorenylacetamide. J Appl Bacteriol. 1978 Jun; 44(3):365-71.
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  66. Zachariah PK. Release of prostaglandins from perfused rabbit kidneys by catecholamines. IRCS Medical Science. Library Compendium. 1978; 6:7.
  67. Fernandez PG, Zachariah PK. Management of essential hypertension. Newfoundl Med Assoc J. 1978; 20(3):14.
  68. Korula J, Zachariah PK, Geerling S, McManamom P, Fernandez PG. Idiopathic arteritis with reversed coarctation and large vessel amyloidosis. Newfoundl Med Assoc J. 1978; 20(4):9.
  69. Berry DL, Slaga TJ, Wilson NM, Zachariah PK, Namkung MJ, Bracken WM, Juchau MR. Transplacental induction of mixed-function oxygenases in extra-hepatic tissues by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochem Pharmacol. 1977 Aug 1; 26(15):1383-8.
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  70. Zachariah PK, Slaga TJ, Berry DL, Bracken WM, Buty SG, Martinsen CM, Juchau MR. The ability of enteric bacteria to catalyze the covalent binding of bile acids and cholesterol to DNA and their in ability to metabolize benzo(a)pyrene to a binding product and to known metabolites. Cancer Lett. 1977 Jul; 3(1-2):99-105.
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  71. Berry DL, Zachariah PK, Slaga TJ, Juchau MR. Analysis of the biotransformation of benzo [a] pyrene in human fetal and placental tissues with high-pressure liquid chromatography. European Journal of Cancer (Oxford) 1977 Jul; 13(7):667-75.
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  72. Rahimtula AD, Zachariah PK, O'Brien PJ. The effects of antioxidants on the metabolism and mutagenicity of benzo[a]pyrene in vitro. Biochem J. 1977 May 15; 164(2):473-5.
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  73. Namkung MJ, Zachariah PK, Juchau MR. O-sulfonation of N-hydroxy-2-fluorenylacetamide and 7-hydroxy-N-2-fluorenylacetamide in fetal and placental tissues of humans and guinea pigs. Drug Metabolism & Disposition. 1977 May-Jun; 5(3):288-94.
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  74. Zachariah PK, Juchau MR. Inhibition of human placental mixed-function oxidations with carbon monoxide: reversal with monochromatic light. J Steroid Biochem. 1977 Mar; 8(3):221-8.
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  75. Zachariah PK, Liston J. Temperature sensitive cell membrane of a psychotrophic Pseudomonas. Microbios Lett. 1977; 3:55.
  76. Zachariah PK, Morley P. Some reflections on alcoholism in Newfoundland. Newfoundl Med Assoc J. 1977; 19:15.
  77. Juchau MR, Mirkin DL, Zachariah PK. Interactions of various 19-nor steroids with human placental microsomal cytochrome P-450 (P-450hpm). Chem Biol Interact. 1976 Dec; 15(4):337-47.
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  78. Berry DL, Zachariah PK, Namkung MJ, Juchau MR. Transplacental induction of carcinogen-hydroxylating systems with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology & Applied Pharmacology. 1976 Jun; 36(3):569-84.
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  79. Zachariah PK, Lee QP, Symms KG, Juchau MR. Further studies on the properties of human placental microsomal cytochrome P-450. Biochem Pharmacol. 1976 Apr 1; 25(7):793-800.
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  80. Liston J, Zachariah PK. Utilization of amino acids and carbohydrates by Salmonella serotypes at 22 degrees and 12 degrees. J Appl Bacteriol. 1976 Feb; 40(1):115-7.
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  81. Zachariah PK. Arterial blood levels of diazepam and its effect on EEG patterns. IRCS Medical Science. Library Compendium. 1976; 4:128.
  82. Pedersen MG, Hersberger WK, Zachariah PK, Juchau MR. Hepatic biotransformation of environmental xenobiotics in six strains of rainbow trout (Salmo gairdneri). J Fish Res Board Can. 1976; 33:666.
  83. Zachariah PK, Liston J. Temperature-induced alanine oxidation in a psychrotrophic Pseudomonas. Can J Microbiol. 1975 Dec; 21(12):2028-33.
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  84. Lee QP, Zachariah PK, Juchau MR. Differential inhibition of androst-4-en-3,17-dione aromatization by carbon monoxide in the presence of estr-4-en-3,17-dione. Steroids. 1975 Nov; 26(5):571-8.
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  85. Juchau MR, Namkung MJ, Berry DL, Zachariah PK. Oxidative biotransformation of 2-acetylaminofluorene in fetal and placental tissues of humans and monkeys. Correlations with aryl hydrocarbon hydroxylase activities. Drug Metabolism & Disposition. 1975 Nov-Dec; 3(6):493-501.
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  86. Juchau MR, Zachariah PK. Displacement of carbon monoxide from placental cytochrome P-450 by steroids: antagonistic effects of androstenedione and 19- norandrostenedione. Biochem Biophys Res Commun. 1975 Aug 4; 65(3):1026-32.
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  87. Juchau MR, Zachariah PK. Comparative studies on the oxidation and reduction of drug substrates in human placental versus rat hepatic microsomes. Biochem Pharmacol. 1975 Jan 15; 24(2):227-33.
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  88. Zachariah PK, Juchau MR. Spectral characteristics of human fetal adrenal microsomes. Life Sci. 1975 Jan 1; 16(1):55-63.
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  89. Zachariah PK, Juchau MR. Interaction of steroids with human placental cytochrome P-450 in the presence of carbon monoxide. Life Sci. 1975; 16:1689.
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  90. Zachariah PK, Juchau MR. Apparent conversion of placental cytochrome P-420 to P-450 with p-chloromercuribenzoate. Biochem Pharmacol. 1974 Aug; 23(15):2195-9.
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  91. Juchau MR, Zachariah PK, Colson J, Symms KG, Krasner J, Yaffe SJ. Studies on human placental carbon monoxide-binding cytochromes. Drug Metabolism & Disposition. 1974 Jan-Feb; 2(1):79-86.
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  92. Zachariah PK, Juchau MR. The role of gut flora in the reduction of aromatic nitro-groups. Drug Metabolism & Disposition. 1974 Jan-Feb; 2(1):74-8.
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  93. Zachariah P, Liston J. Temperature adaptability of psychrotrophic Pseudomonas. Appl Microbiol. 1973 Sep; 26(3):437-8.
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