Publications

  1. Dyck PJ, Albers JW, Andersen H, Arezzo JC, Biessels GJ, Bril V, Feldman EL, Litchy WJ, O'Brien PC, Russell JW, on behalf of the Toronto Expert Panel on Diabetic Neuropathy*. Diabetic Polyneuropathies: Update on Research Definition, Diagnostic Criteria and Estimation of Severity. Diabetes Metab Res Rev. 2011 Jun 21. [Epub ahead of print]
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  2. Jayasinghe Y, Cha R, Horn-Ommen J, O'Brien P, Simmons PS. Establishment of normative data for the amount of breast tissue present in healthy children up to two years of age. J Pediatr Adolesc Gynecol. 2010 Oct; 23(5):305-11. Epub 2010 May 21.
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  3. Hennekens CH, Hebert PR, Schneider WR, O'Brien P, Demets D, Borer JS. Academic perspectives on the United States Food and Drug Administration's guidance for industry on diabetes mellitus. Contemp Clin Trials. 2010 Sep; 31(5):411-3. Epub 2010 Jun 19.
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  4. Dyck PJ, Overland CJ, Low PA, Litchy WJ, Davies JL, Dyck PJ, O'Brien PC, Cl vs. NPhys Trial Investigators, Albers JW, Andersen H, Bolton CF, England JD, Klein CJ, Llewelyn JG, Mauermann ML, Russell JW, Singer W, Smith AG, Tesfaye S, Vella A. Signs and symptoms versus nerve conduction studies to diagnose diabetic sensorimotor polyneuropathy: Cl vs. NPhys trial. Muscle Nerve. 2010 Aug; 42(2):157-64.
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  5. Srinivasan M, Irving BA, Frye RL, O'Brien P, Hartman SJ, McConnell JP, Nair KS. Effects on lipoprotein particles of long-term dehydroepiandrosterone in elderly men and women and testosterone in elderly men. J Clin Endocrinol Metab. 2010 Apr; 95(4):1617-25. Epub 2010 Feb 05.
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  6. Karakelides H, Irving BA, Short KR, O'Brien P, Nair KS. Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function. Diabetes. 2010 Jan; 59(1):89-97. Epub 2009 Oct 15.
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  7. Mundi MS, Karpyak MV, Koutsari C, Votruba SB, O'Brien PC, Jensen MD. Body fat distribution, adipocyte size, and metabolic characteristics of nondiabetic adults. J Clin Endocrinol Metab. 2010 Jan; 95(1):67-73. Epub 2009 Nov 04.
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  8. Koutsari C, Ali AH, Nair KS, Rizza RA, O'Brien P, Khosla S, Jensen MD. Fatty acid metabolism in the elderly: effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women. J Clin Endocrinol Metab. 2009 Sep; 94(9):3414-23. Epub 2009 Jun 30.
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  9. Kantarci K, Weigand SD, Przybelski SA, Shiung MM, Whitwell JL, Negash S, Knopman DS, Boeve BF, O'Brien PC, Petersen RC, Jack CR Jr. Risk of dementia in MCI: combined effect of cerebrovascular disease, volumetric MRI, and 1H MRS. Neurology. 2009 Apr 28; 72(17):1519-25.
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  10. Henderson GC, Dhatariya K, Ford GC, Klaus KA, Basu R, Rizza RA, Jensen MD, Khosla S, O'Brien P, Nair KS. Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements. FASEB J. 2009 Feb; 23(2):631-41. Epub 2008 Sep 30.
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  11. Huang P, Woolson RF, O'Brien PC. A rank-based sample size method for multiple outcomes in clinical trials. Stat Med. 2008 Jul 20; 27(16):3084-104.
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  12. Jack CR Jr, Weigand SD, Shiung MM, Przybelski SA, O'Brien PC, Gunter JL, Knopman DS, Boeve BF, Smith GE, Petersen RC. Atrophy rates accelerate in amnestic mild cognitive impairment. Neurology. 2008 May 6; 70(19 Pt 2):1740-52. Epub 2007 Nov 21.
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  13. O'Brien PC. Discussion on "Second-Guessing Clinical Trial Designs" by Jonathan J Shuster and Myron N Chang. Sequential Analysis. 2008; 27:26-9.
  14. Dyck PJ, Norell JE, Tritschler H, Schuette K, Samigullin R, Ziegler D, Bastyr EJ 3rd, Litchy WJ, O'Brien PC. Challenges in design of multicenter trials: end points assessed longitudinally for change and monotonicity. Diabetes Care. 2007 Oct; 30(10):2619-25. Epub 2007 May 18
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  15. Huang P, Woolsen AF, O'Brien PC. A rank-based sample size method for multiple outcomes in clinical trials. Statistics in Medicine. 2007 Oct.
  16. Kantarci K, Weigand SD, Petersen RC, Boeve BF, Knopman DS, Gunter J, Reyes D, Shiung M, O'Brien PC, Smith GE, Ivnik RJ, Tangalos EG, Jack CR Jr. Longitudinal 1H MRS changes in mild cognitive impairment and Alzheimer's disease. Neurobiol Aging. 2007 Sep; 28(9):1330-9. Epub 2006 Jul 24.
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  17. Service FJ, O'Brien PC. Influence of glycemic variables on hemoglobin A1c. Endocr Pract. 2007 Jul-Aug; 13(4):350-4.
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  18. Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, O'Brien PC, Johnson MG, Williams AR, Cutshall SM, Mundy LM, Rizza RA, McMahon MM. Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery: a randomized trial. Ann Intern Med. 2007 Feb 20; 146(4):233-43.
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  19. Leibson CL, Long KH, Maraganore DM, Bower JH, Ransom JE, O'Brien PC, Rocca WA. Direct medical costs associated with Parkinson's disease: a population-based study. Mov Disord. 2006 Nov; 21(11):1864-71.
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  20. Nair KS, Rizza RA, O'Brien P, Dhatariya K, Short KR, Nehra A, Vittone JL, Klee GG, Basu A, Basu R, Cobelli C, Toffolo G, Dalla Man C, Tindall DJ, Melton LJ 3rd, Smith GE, Khosla S, Jensen MD. DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med. 2006 Oct 19; 355(16):1647-59.
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  21. Dyck PJ, Davies JL, Clark VM, Litchy WJ, Dyck PJ, Klein CJ, Rizza RA, Pach JM, Klein R, Larson TS, Melton LJ 3rd, O'Brien PC. Modeling chronic glycemic exposure variables as correlates and predictors of microvascular complications of diabetes. Diabetes Care. 2006 Oct; 29(10):2282-8.
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  22. Singer W, Sandroni P, Opfer-Gehrking TL, Suarez GA, Klein CM, Hines S, O'Brien PC, Slezak J, Low PA. Pyridostigmine treatment trial in neurogenic orthostatic hypotension. Arch Neurol. 2006 Apr; 63(4):513-8. Epub 2006 Feb 13.
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  23. Leibson CL, Maraganore DM, Bower JH, Ransom JE, O'brien PC, Rocca WA. Comorbid conditions associated with Parkinson's disease: a population-based study. Mov Disord. 2006 Apr; 21(4):446-55.
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  24. Jack CR Jr, Shiung MM, Weigand SD, O'Brien PC, Gunter JL, Boeve BF, Knopman DS, Smith GE, Ivnik RJ, Tangalos EG, Petersen RC. Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI. Neurology. 2005 Oct 25; 65(8):1227-31.
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  25. Dyck PJ, O'Brien PC, Litchy WJ, Harper CM, Klein CJ, Dyck PJ. Monotonicity of nerve tests in diabetes: subclinical nerve dysfunction precedes diagnosis of polyneuropathy. Diabetes Care. 2005 Sep; 28(9):2192-200.
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  26. Service FJ, O'Brien PC. Increasing serum betahydroxybutyrate concentrations during the 72-hour fast: evidence against hyperinsulinemic hypoglycemia. J Clin Endocrinol Metab. 2005 Aug; 90(8):4555-8. Epub 2005 May 10.
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  27. Wingerchuk DM, Benarroch EE, O'Brien PC, Keegan BM, Lucchinetti CF, Noseworthy JH, Weinshenker BG, Rodriguez M. A randomized controlled crossover trial of aspirin for fatigue in multiple sclerosis. Neurology. 2005 Apr 12; 64(7):1267-9.
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  28. Kantarci K, Petersen RC, Boeve BF, Knopman DS, Weigand SD, O'Brien PC, Shiung MM, Smith GE, Ivnik RJ, Tangalos EG, Jack CR Jr. DWI predicts future progression to Alzheimer disease in amnestic mild cognitive impairment. Neurology. 2005 Mar 8; 64(5):902-4.
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  29. O'Brien PC, Zhang D, Bailey KR. Semi-parametric and non-parametric methods for clinical trials with incomplete data. Stat Med. 2005 Feb 15; 24(3):341-58.
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  30. Suarez GA, Clark VM, Norell JE, Kottke TE, Callahan MJ, O'Brien PC, Low PA, Dyck PJ. Sudden cardiac death in diabetes mellitus: risk factors in the Rochester diabetic neuropathy study. J Neurol Neurosurg Psychiatry. 2005 Feb; 76(2):240-5.
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  31. Low PA, Benrud-Larson LM, Sletten DM, Opfer-Gehrking TL, Weigand SD, O'Brien PC, Suarez GA, Dyck PJ. Autonomic symptoms and diabetic neuropathy - A population-based study. Diabetes Care. 2004 Dec; 27(12):2942-7.
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  32. Lawn ND, Bamlet WR, Radhakrishnan K, O'Brien PC, So EL. Injuries due to seizures in persons with epilepsy - A population-based study. Neurology. 2004 Nov 9; 63(9):1565-70.
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  33. Kantarci K, Petersen RC, Boeve BF, Knopman DS, Tang-Wai DF, O'Brien PC, Weigand SD, Edland SD, Smith GE, Ivnik RJ, Ferman TJ, Tangalos EG, Jack CR. H-1 MR spectroscopy in common dementias. Neurology. 2004 Oct 26; 63(8):1393-8.
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  34. Kantarci K, Petersen RC, Boeve BF, Knopman DS, Tang-Wai DF, O'Brien PC, Weigand SD, Edland SD, Smith GE, Ivnik RJ, Ferman TJ, Tangalos EG, Jack CR Jr. 1H MR spectroscopy in common dementias. Neurology. 2004 Oct 26; 63(8):1393-8.
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  35. Windebank AJ, Sorenson EJ, Civil R, O'Brien PC. Role of insulin-like growth factor-I in the treatment of painful small fiber predominant neuropathy. J Peripher Nerv Syst. 2004 Sep; 9(3):183-9.
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  36. Buskirk SJ, Pinkstaff DM, Petrou SP, Wehle MJ, Broderick GA, Young PR, Weigand SD, O'Brien PC, Igel TC. Acute urinary retention after transperineal template-guided prostate biopsy. Int J Radiat Oncol Biol Phys. 2004 Aug 1; 59(5):1360-6.
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  37. Jack CR Jr, Shiung MM, Gunter JL, O'Brien PC, Weigand SD, Knopman DS, Boeve BF, Ivnik RJ, Smith GE, Cha RH, Tangalos EG, Petersen RC. Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD. Neurology. 2004 Feb 24; 62(4):591-600.
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  38. Janson J, Laedtke T, Parisi JE, O'Brien P, Petersen RC, Butler PC. Increased risk of type 2 diabetes in Alzheimer disease. Diabetes. 2004 Feb; 53(2):474-81.
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  39. Meschia JF, Lojacono MA, Miller MJ, Brott TG, Atkinson EJ, O'Brien PC. Reliability of the questionnaire for verifying stroke-free status. Cerebrovasc Dis. 2004; 17(2-3):218-23. Epub 2003 Dec 29.
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  40. Karrison TG, O'Brien PC. A rank-sum-type test for paired data with multiple endpoints. J Applied Stat. 2004; 31:1-10.
  41. Machulda MM, Ward HA, Borowski B, Gunter JL, Cha RH, O'Brien PC, Petersen RC, Boeve BF, Knopman D, Tang-Wai DF, Ivnik RJ, Smith GE, Tangalos EG, Jack CR Jr. Comparison of memory fMRI response among normal, MCI, and Alzheimer's patients. Neurology. 2003 Aug 26; 61(4):500-6.
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  42. Meschia JF, Atkinson EJ, O'Brien PC, Brott TG, Brown RD Jr, Hardy J. Familial clustering of stroke according to proband age at onset of presenting ischemic stroke. Stroke. 2003 Jul; 34(7):e89-91. Epub 2003 Jun 19.
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  43. Kornick CA, Santiago-Palma J, Schulman G, O'Brien PC, Weigand S, Payne R, Manfredi PL. A safe and effective method for converting patients from transdermal to intravenous fentanyl for the treatment of acute cancer-related pain. Cancer. 2003 Jun 15; 97(12):3121-4.
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  44. Nielsen S, Guo Z, Albu JB, Klein S, O'Brien PC, Jensen MD. Energy expenditure, sex, and endogenous fuel availability in humans. J Clin Invest. 2003 Apr; 111(7):981-8.
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  45. Vella A, Service FJ, O'Brien PC. Glucose counterregulatory hormones in the 72-hour fast. Endocr Pract. 2003 Mar-Apr; 9(2):115-8.
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  46. Ametov AS, Barinov A, Dyck PJ, Hermann R, Kozlova N, Litchy WJ, Low PA, Nehrdich D, Novosadova M, O'Brien PC, Reljanovic M, Samigullin R, Schuette K, Strokov I, Tritschler H, Wessel K, Yakhno N, Ziegler D. The sensory symptoms of diabetic polyneuropathy are improved with alpha-lipoic acid - The SYDNEY trial. Diabetes Care. 2003 Mar; 26(3):770-6.
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  47. Thomas RJ, Palumbo PJ, Melton LJ, Roger VL, Ransom J, O'Brien PC, Leibson CL. Trends in the mortality burden associated with diabetes mellitus - A population-based study in Rochester, Minn, 1970-1994. Arch Intern Med. 2003 Feb 24; 163(4):445-51.
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  48. Dyck PJ, Litchy WJ, Daube JR, Harper CM, Dyck PJB, Davies J, O'Brien PC. Individual attributes versus composite scores of nerve conduction abnormality: Sensitivity, reproducibility, and concordance with impairment. Muscle & Nerve. 2003 Feb; 27(2):202-10.
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  49. Gerber TC, O'Brien PC, Pastor K, Kuzo RS, Blackshear JL, Morin RL. Evaluation of reconstruction windows for multislice computed tomography in quantification of coronary calcium. Invest Radiol. 2003 Feb; 38(2):108-18.
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  50. Jack CR Jr, Slomkowski M, Gracon S, Hoover TM, Felmlee JP, Stewart K, Xu Y, Shiung M, O'Brien PC, Cha R, Knopman D, Petersen RC. MRI as a biomarker of disease progression in a therapeutic trial of milameline for AD. Neurology. 2003 Jan 28; 60(2):253-60.
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  51. Ukleja A, Scolapio JS, McConnell JP, Dickson RC, Nguyen JH, O'Brien PC. Serum and hepatic vitamin E assessment in cirrhotics before transplantation. JPEN J Parenter Enteral Nutr. 2003 Jan-Feb; 27(1):71-3.
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  52. Radhakrishnan K, So EL, Silbert PL, Cascino GD, Marsh WR, Cha RH, O'Brien PC. Prognostic implications of seizure recurrence in the first year after anterior temporal lobectomy. Epilepsia. 2003 Jan; 44(1):77-80.
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  53. Gerber TC, Kuzo RS, Lane GE, O'Brien PC, Karstaedt N, Morin RL, Safford RE, Blackshear JL, Pietan JH. Image quality in a standardized algorithm for minimally invasive coronary angiography with multislice spiral computed tomography. J Comput Assist Tomogr. 2003 Jan-Feb; 27(1):62-9.
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  54. Willis F, Graff-Radford N, Pinto M, Lawson L, Adamson J, Epstein D, Parfitt F, Hutton M, O'Brien PC. Apolipoprotein epsilon4 allele frequency in young Africans of Ugandan descent versus African Americans. J Natl Med Assoc. 2003 Jan; 95(1):71-6.
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  55. Bratton RL, Montero DP, Adams KS, Novas MA, McKay TC, Hall LJ, Foust JG, Mueller MB, O'Brien PC, Atkinson EJ, Maurer MS. Effect of "ionized" wrist bracelets on musculoskeletal pain: a randomized, double-blind, placebo-controlled trial. Mayo Clin Proc. 2002 Nov; 77(11):1164-8.
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  56. Parashos SA, Maraganore DM, O'Brien PC, Rocca WA. Medical services utilization and prognosis in Parkinson disease: a population-based study. Mayo Clin Proc. 2002 Sep; 77(9):918-25.
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  57. Dyck PJ, Turner DW, Davies JL, O'Brien PC, Dyck PJ, Rask CA, rhNGF group. Electronic case-report forms of symptoms and impairments of peripheral neuropathy. Can J Neurol Sci. 2002 Aug; 29(3):258-66.
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  58. Edland SD, Xu Y, Plevak M, O'Brien P, Tangalos EG, Petersen RC, Jack CR. Total intracranial volume: Normative values and lack of association with Alzheimer's disease. Neurology. 2002 Jul 23; 59(2):272-4.
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  59. Hellinger WC, Yao JD, Alvarez S, Blair JE, Cawley JJ, Paya CV, O'Brien PC, Spivey JR, Dickson RC, Harnois DM, Douglas DD, Hughes CB, Nguyen JH, Mulligan DC, Steers JL. A randomized, prospective, double-blinded evaluation of selective bowel decontamination in liver transplantation. Transplantation. 2002 Jun 27; 73(12):1904-9.
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  60. Burns TM, Taly A, O'Brien PC, Dyck PJ. Clinical versus quantitative vibration assessment: improving clinical performance. J Peripher Nerv Syst. 2002 Jun; 7(2):112-7.
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  61. Burke JP, O'Brien P, Ransom J, Palumbo PJ, Lydick E, Yawn BP, Melton LJ, Leibson CL. Impact of case ascertainment on recent trends in diabetes incidence in Rochester, Minnesota. Am J Epidemiol. 2002 May 1; 155(9):859-65.
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  62. Ukleja A, Scolapio JS, McConnell JP, Spivey JR, Dickson RC, Nguyen JH, O'Brien PC. Nutritional assessment of serum and hepatic vitamin A levels in patients with cirrhosis. JPEN J Parenter Enteral Nutr. 2002 May-Jun; 26(3):184-8.
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  63. Jack CR Jr, Dickson DW, Parisi JE, Xu YC, Cha RH, O'Brien PC, Edland SD, Smith GE, Boeve BF, Tangalos EG, Kokmen E, Petersen RC. Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia. Neurology. 2002 Mar 12; 58(5):750-7.
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  64. Scolapio JS, Ukleja A, McGreevy K, Burnett OL, O'Brien PC. Nutritional problems in end-stage liver disease - Contribution of impaired gastric emptying and ascites. J Clin Gastroenterol. 2002 Jan; 34(1):89-93.
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  65. Kantarci K, Xu Y, Shiung MM, O'Brien PC, Cha RH, Smith GE, Ivnik RJ, Boeve BF, Edland SD, Kokmen E, Tangalos EG, Petersen RC, Jack CR Jr. Comparative diagnostic utility of different MR modalities in mild cognitive impairment and Alzheimer's disease. Dement Geriatr Cogn Disord. 2002; 14(4):198-207.
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  66. Meschia JF, Brown RD Jr, Brott TG, Hardy J, Atkinson EJ, O'Brien PC. Feasibility of an affected sibling pair study in ischemic stroke: results of a 2-center family history registry. Stroke. 2001 Dec 1; 32(12):2939-41.
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  67. Jack CR Jr, O'Brien PC, Rettman DW, Shiung MM, Xu Y, Muthupillai R, Manduca A, Avula R, Erickson BJ. FLAIR histogram segmentation for measurement of leukoaraiosis volume. J Magn Reson Imaging. 2001 Dec; 14(6):668-76.
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  68. Machulda MM, Ward HA, Cha R, O'Brien P, Jack CR Jr. Functional inferences vary with the method of analysis in fMRI. Neuroimage. 2001 Nov; 14(5):1122-7.
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  69. Dyck PJ, Velosa JA, Pach JM, Sterioff S, Larson TS, Norell JE, O'Brien PC, Dyck PJ. Increased weakness after pancreas and kidney transplantation. Transplantation. 2001 Oct 27; 72(8):1403-8.
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  70. Smith GE, O'Brien PC, Ivnik RJ, Kokmen E, Tangalos EG. Prospective analysis of risk factors for nursing home placement of dementia patients. Neurology. 2001 Oct 23; 57(8):1467-73.
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  71. Service FJ, O'Brien PC. The relation of glycaemia to the risk of development and progression of retinopathy in the Diabetic Control and Complications Trial. Diabetologia. 2001 Oct; 44(10):1215-20.
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  72. Sencakova D, Graff-Radford NR, Willis FB, Lucas JA, Parfitt F, Cha RH, O'Brien PC, Petersen RC, Jack CR Jr. Hippocampal atrophy correlates with clinical features of Alzheimer disease in African Americans. Arch Neurol. 2001 Oct; 58(10):1593-7.
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  73. Suarez GA, Chalk CH, Russell JW, Kim SM, O'Brien PC, Dyck PJ. Diagnostic accuracy and certainty from sequential evaluations in peripheral neuropathy. Neurology. 2001 Sep 25; 57(6):1118-20.
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  74. Short RA, Bowen RL, O'Brien PC, Graff-Radford NR. Elevated gonadotropin levels in patients with Alzheimer disease. Mayo Clin Proc. 2001 Sep; 76(9):906-9.
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  75. Apfel SC, Asbury AK, Bril V, Burns TM, Campbell JN, Chalk CH, Dyck PJ, Dyck PJ, Feldman EL, Fields HL, Grant IA, Griffin JW, Klein CJ, Lindblom U, Litchy WJ, Low PA, Melanson M, Mendell JR, Merren MD, O'Brien PC, Rendell M, Rizza RA, Service FJ, Thomas Positive neuropathic sensory symptoms as endpoints in diabetic neuropathy trials. J Neurol Sci. 2001 Aug 15; 189(1-2):3-5.
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  76. Buskirk SJ, Pisansky TM, Atkinson EJ, Schild SE, O'Brien PC, Wolfe JT, Zincke H. Lymph node-positive prostate cancer: evaluation of the results of the combination of androgen deprivation therapy and radiation therapy. Mayo Clin Proc. 2001 Jul; 76(7):702-6.
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  77. Noseworthy JH, O'Brien PC, Petterson TM, Weis J, Stevens L, Peterson WK, Sneve D, Cross SA, Leavitt JA, Auger RG, Weinshenker BG, Dodick DW, Wingerchuk DM, Rodriguez M. A randomized trial of intravenous immunoglobulin in inflammatory demyelinating optic neuritis. Neurology. 2001 Jun 12; 56(11):1514-22.
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  78. Ahlman B, Charlton M, Fu A, Berg C, O'Brien P, Nair KS. Insulin's effect on synthesis rates of liver proteins. A swine model comparing various precursors of protein synthesis. Diabetes. 2001 May; 50(5):947-54.
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  79. Kantarci K, Jack CR Jr, Xu YC, Campeau NG, O'Brien PC, Smith GE, Ivnik RJ, Boeve BF, Kokmen E, Tangalos EG, Petersen RC. Mild cognitive impairment and Alzheimer disease: regional diffusivity of water. Radiology. 2001 Apr; 219(1):101-7.
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  80. Leibson CL, Katusic SK, Barbaresi WJ, Ransom J, O'Brien PC. Use and costs of medical care for children and adolescents with and without attention-deficit/hyperactivity disorder. JAMA. 2001 Jan 3; 285(1):60-6.
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  81. Noseworthy JH, O'Brien PC, Weinshenker BG, Weis JA, Petterson TM, Erickson BJ, Windebank AJ, Whisnant JP, Stolp-Smith KA, Harper CM Jr, Low PA, Romme LJ, Johnson M, An KN, Rodriguez M. IV immunoglobulin does not reverse established weakness in MS. Neurology. 2000 Oct 24; 55(8):1135-43.
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  82. Jack CR Jr, Petersen RC, Xu Y, O'Brien PC, Smith GE, Ivnik RJ, Boeve BF, Tangalos EG, Kokmen E. Rates of hippocampal atrophy correlate with change in clinical status in aging and AD. Neurology. 2000 Aug 22; 55(4):484-89.
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  83. Kimura K, Hunter SF, Thollander MS, Loftus EV Jr, Melton LJ 3rd, O'Brien PC, Rodriguez M, Phillips SF. Concurrence of inflammatory bowel disease and multiple sclerosis. Mayo Clin Proc. 2000 Aug; 75(8):802-6.
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  84. Kantarci K, Jack CR Jr, Xu YC, Campeau NG, O'Brien PC, Smith GE, Ivnik RJ, Boeve BF, Kokmen E, Tangalos EG, Petersen RC. Regional metabolic patterns in mild cognitive impairment and Alzheimer's disease: A 1H MRS study. Neurology. 2000 Jul 25; 55(2):210-7.
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  85. Mosewich RK, So EL, O'Brien TJ, Cascino GD, Sharbrough FW, Marsh WR, Meyer FB, Jack CR, O'Brien PC. Factors predictive of the outcome of frontal lobe epilepsy surgery. Epilepsia. 2000 Jul; 41(7):843-9.
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  86. Weinshenker BG, Hebrink DD, Klein C, Atkinson EJ, O'Brien PC, McMurray CT. Genetic variation in the B7-1 gene in patients with multiple sclerosis. J Neuroimmunol. 2000 Jun 26; 105(2):184-8.
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  87. Xu Y, Jack CR Jr, O'Brien PC, Kokmen E, Smith GE, Ivnik RJ, Boeve BF, Tangalos RG, Petersen RC. Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD. Neurology. 2000 May 9; 54(9):1760-7.
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  88. Meschia JF, Brott TG, Chukwudelunzu FE, Hardy J, Brown RD Jr, Meissner I, Hall LJ, Atkinson EJ, O'Brien PC. Verifying the stroke-free phenotype by structured telephone interview. Stroke. 2000 May; 31(5):1076-80.
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  89. Smith GE, Kokmen E, O'Brien PC. Risk factors for nursing home placement in a population-based dementia cohort. J Am Geriatr Soc. 2000 May; 48(5):519-25.
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  90. Klingler PJ, Hinder RA, Wetscher GJ, Davis DM, Achem SR, Seelig MH, O'Brien P, DeVault KR. Accurate placement of the esophageal pH electrode for 24-hour pH monitoring using a combined pH/manometry probe. Am J Gastroenterol. 2000 Apr; 95(4):906-9.
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  91. Dyck PJ, Dyck PJB, Velosa JA, Larson TS, O'Brien PC. Patterns of quantitative sensation testing of hypoesthesia and hyperalgesia are predictive of diabetic polyneuropathy - a study of three cohorts. Diabetes Care. 2000 Apr; 23(4):510-517.
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  92. Petersen RC, Jack CR Jr, Xu YC, Waring SC, O'Brien PC, Smith GE, Ivnik RJ, Tangalos EG, Boeve BF, Kokmen E. Memory and MRI-based hippocampal volumes in aging and AD. Neurology. 2000 Feb 8; 54(3):581-7.
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  93. Beard CM, Hartmann LC, Keeney GL, Crowson CS, Malkasian GD, O'Brien PC, Melton LJ 3rd. Endometrial cancer in Olmsted County, MN: trends in incidence, risk factors and survival. Ann Epidemiol. 2000 Feb; 10(2):97-105.
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  94. Larson TS, Santanello N, Shahinfar S, O'Brien PC, Palumbo PJ, Melton LJ 3rd, Leibson CL. Trends in persistent proteinuria in adult-onset diabetes: a population-based study. Diabetes Care. 2000 Jan; 23(1):51-6.
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  95. Beard CM, Hartmann LC, Atkinson EJ, O'Brien PC, Malkasian GD, Keeney GL, Melton LJ 3rd. The epidemiology of ovarian cancer: a population-based study in Olmsted County, Minnesota, 1935-1991. Ann Epidemiol. 2000 Jan; 10(1):14-23.
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  96. Waring SC, Rocca WA, Petersen RC, O'Brien PC, Tangalos EG, Kokmen E. Postmenopausal estrogen replacement therapy and risk of Alzheimer's disease: a population based study. Menopause Dig. 2000; 12:6-7.
  97. Weinshenker BG, O'Brien PC, Petterson TM, Noseworthy JH, Lucchinetti CF, Dodick DW, Pineda AA, Stevens LN, Rodriguez M. A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease. Ann Neurol. 1999 Dec; 46(6):878-86.
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  98. Wingerchuk DM, Hogancamp WF, O'Brien PC, Weinshenker BG. The clinical course of neuromyelitis optica (Devic's syndrome). Neurology. 1999 Sep 22; 53(5):1107-14.
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  99. Dyck PJ, Davies JL, Wilson DM, Service FJ, Melton LJ 3rd, O'Brien PC. Risk factors for severity of diabetic polyneuropathy: intensive longitudinal assessment of the Rochester Diabetic Neuropathy Study cohort. Diabetes Care. 1999 Sep; 22(9):1479-86.
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  100. Proctor DN, O'Brien PC, Atkinson EJ, Nair KS. Comparison of techniques to estimate total body skeletal muscle mass in people of different age groups. Am J Physiol. 1999 Sep; 277(3 Pt 1):E489-95.
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  101. Myllykangas L, Polvikoski T, Sulkava R, Verkkoniemi A, Crook R, Tienari PJ, Pusa AK, Niinisto L, O'Brien P, Kontula K, Hardy J, Haltia M, Perez-Tur J. Genetic association of alpha(2)-macroglobulin with Alzheimer's disease in a Finnish elderly population. Ann Neurol. 1999 Sep; 46(3):382-90.
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  102. Leibson C, Owens T, O'Brien P, Waring S, Tangalos E, Hanson V, Plevak M, Kokmen E. Use of physician and acute care services by persons with and without Alzheimer's disease: a population-based comparison. J Am Geriatr Soc. 1999 Jul; 47(7):864-9.
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  103. Jensen MD, Hensrud D, O'Brien PC, Nielsen S. Collection and interpretation of plasma leptin concentration data in humans. Obes Res. 1999 May; 7(3):241-5.
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  104. Weinshenker BG, Hebrink D, Wingerchuk DM, Klein CJ, Atkinson E, O'Brien PC, McMurray CT. Genetic variants in the tumor necrosis factor receptor 1 gene in patients with MS. Neurology. 1999 Apr 22; 52(7):1500-3.
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  105. Jack CR Jr, Petersen RC, Xu YC, O'Brien PC, Smith GE, Ivnik RJ, Boeve BF, Waring SC, Tangalos EG, Kokmen E. Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment. Neurology. 1999 Apr 22; 52(7):1397-403.
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  106. Waring SC, Rocca WA, Petersen RC, O'Brien PC, Tangalos EG, Kokmen E. Postmenopausal estrogen replacement therapy and risk of AD: a population-based study. Neurology. 1999 Mar 23; 52(5):965-70.
  107. Suarez GA, Opfer-Gehrking TL, Offord KP, Atkinson EJ, O'Brien PC, Low PA. The Autonomic Symptom Profile: a new instrument to assess autonomic symptoms. Neurology. 1999 Feb; 52(3):523-8.
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  108. Wu CL, Denq JC, Harper CM, O'Brien PC, Low PA. Clinical and electrophysiologic attributes as predictors of results of autonomic function tests. Clin Auton Res. 1998 Dec; 8(6):347-51.
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  109. Novak V, Novak P, Opfer-Gehrking TL, O'Brien PC, Low PA. Clinical and laboratory indices that enhance the diagnosis of postural tachycardia syndrome. Mayo Clin Proc. 1998 Dec; 73(12):1141-50.
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  110. Ahlskog JE, Waring SC, Petersen RC, Esteban-Santillan C, Craig UK, O'Brien PC, Plevak MF, Kurland LT. Olfactory dysfunction in Guamanian ALS, parkinsonism, and dementia. Neurology. 1998 Dec; 51(6):1672-7.
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  111. Ficker DM, So EL, Shen WK, Annegers JF, O'Brien PC, Cascino GD, Belau PG. Population-based study of the incidence of sudden unexplained death in epilepsy. Neurology. 1998 Nov; 51(5):1270-4.
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  112. Denq JC, O'Brien PC, Low PA. Normative data on phases of the Valsalva maneuver. J Clin Neurophysiol. 1998 Nov; 15(6):535-40.
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  113. Noseworthy JH, O'Brien P, Erickson BJ, Lee D, Sneve D, Ebers GC, Rice GP, Auty A, Hader WJ, Kirk A, Duquette P, Carter J, Francis G, Metz L, Shuster E. The Mayo Clinic-Canadian Cooperative trial of sulfasalazine in active multiple sclerosis. Neurology. 1998 Nov; 51(5):1342-52.
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  114. Jack CR Jr, Petersen RC, Xu Y, O'Brien PC, Smith GE, Ivnik RJ, Tangalos EG, Kokmen E. Rate of medial temporal lobe atrophy in typical aging and Alzheimer's disease. Neurology. 1998 Oct; 51(4):993-9.
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  115. Beard CM, Waring SC, O'Brien PC, Kurland LT, Kokmen E. Nonsteroidal anti-inflammatory drug use and Alzheimer's disease: a case-control study in Rochester, Minnesota, 1980 through 1984. Mayo Clin Proc. 1998 Oct; 73(10):951-5.
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  116. Radhakrishnan K, So EL, Silbert PL, Jack CR Jr, Cascino GD, Sharbrough FW, O'Brien PC. Predictors of outcome of anterior temporal lobectomy for intractable epilepsy: a multivariate study. Neurology. 1998 Aug; 51(2):465-71.
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  117. Chabolla DR, Maraganore DM, Ahlskog JE, O'Brien PC, Rocca WA. Drug-induced parkinsonism as a risk factor for Parkinson's disease: a historical cohort study in Olmsted County, Minnesota. Mayo Clin Proc. 1998 Aug; 73(8):724-7.
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  118. Stolp-Smith KA, Atkinson EJ, Campion ME, O'Brien PC, Rodriguez M. Health care utilization in multiple sclerosis: a population-based study in Olmsted County, MN. Neurology. 1998 Jun; 50(6):1594-600.
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  119. Dyck PJ, Dyck PJB, Kennedy WR, Kesserwani H, Melanson M, Ochoa J, Shy M, Stevens JC, Suarez GA, O'Brien PC. Limitations of quantitative sensory testing when patients are biased toward a bad outcome. Neurology. 1998 May; 50(5):1213.
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  120. Moller N, O'Brien P, Nair KS. Disruption of the relationship between fat content and leptin levels with aging in humans. J Clin Endocrinol Metab. 1998 Mar; 83(3):931-4.
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  121. Jack CR Jr, Petersen RC, Xu YC, O'Brien PC, Waring SC, Tangalos EG, Smith GE, Ivnik RJ, Thibodeau SN, Kokmen E. Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease. Ann Neurol. 1998 Mar; 43(3):303-10.
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  122. Wijdicks EF, Kokmen E, O'Brien PC. Measurement of impaired consciousness in the neurological intensive care unit: a new test. Journal of Neurology, Neurosurgery & Psychiatry. 1998 Jan; 64(1):117-9.
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  123. Kokmen E, Ozekmekci FS, Cha RH, Obrien PJ. Testing for apraxia in neurological patients - a descriptive study in two diverse cultures. Eur J Neurol. 1998; 5(2):175-180.
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  124. Low PA, Denq JC, Opfer-Gehrking TL, Dyck PJ, O'Brien PC, Slezak JM. Effect of age and gender on sudomotor and cardiovagal function and blood pressure response to tilt in normal subjects. Muscle & Nerve. 1997 Dec; 20(12):1561-8.
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  125. Schrock E, Veldman T, Padilla-Nash H, Ning Y, Spurbeck J, Jalal S, Shaffer LG, Papenhausen P, Kozma C, Phelan MC, Kjeldsen E, Schonberg SA, O'Brien P, Biesecker L, du Manoir S, Ried T. Spectral karyotyping refines cytogenetic diagnostics of constitutional chromosomal abnormalities. Hum Genet. 1997 Dec; 101(3):255-62.
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  126. Lucchinetti CF, Kiers L, O'Duffy A, Gomez MR, Cross S, Leavitt JA, O'Brien P, Rodriguez M. Risk factors for developing multiple sclerosis after childhood optic neuritis. Neurology. 1997 Nov; 49(5):1413-8.
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  127. Campeau NG, Petersen RC, Felmlee JP, O'Brien PC, Jack CR Jr. Hippocampal transverse relaxation times in patients with Alzheimer disease. Radiology. 1997 Oct; 205(1):197-201.
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  128. Leibson CL, Rocca WA, Hanson VA, Cha R, Kokmen E, O'Brien PC, Palumbo PJ. The risk of dementia among persons with diabetes mellitus: a population-based cohort study. Ann N Y Acad Sci. 1997 Sep 26(826):422-7.
  129. Dyck PJ, Melton LJ, Obrien PC, Service FJ. Approaches to improve epidemiological studies of diabetic neuropathy - insights from the Rochester Diabetic Neuropathy Study. Diabetes. 1997 Sep; 46(Suppl 2):S 5-S 8.
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  130. Jack CR Jr, Petersen RC, Xu YC, Waring SC, O'Brien PC, Tangalos EG, Smith GE, Ivnik RJ, Kokmen E. Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease. Neurology. 1997 Sep; 49(3):786-94.
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  131. Service FJ, O'Brien PC, Wise SD, Ness S, LeBlanc SM. Dermal interstitial glucose as an indicator of ambient glycemia. Diabetes Care. 1997 Sep; 20(9):1426-9.
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  132. Leibson CL, O'Brien PC, Atkinson E, Palumbo PJ, Melton LJ 3rd. Relative contributions of incidence and survival to increasing prevalence of adult-onset diabetes mellitus: a population-based study. Am J Epidemiol. 1997 Jul 1; 146(1):12-22.
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  133. Dyck PJ, Davies JL, Litchy WJ, O'Brien PC. Longitudinal assessment of diabetic polyneuropathy using a composite score in the Rochester Diabetic Neuropathy Study cohort. Neurology. 1997 Jul; 49(1):229-39.
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  134. O'Brien PC, Geller NL. Interpreting tests for efficacy in clinical trials with multiple endpoints. Control Clin Trials. 1997 Jun; 18(3):222-7.
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  135. Reeves AL, So EL, Evans RW, Cascino GD, Sharbrough FW, O'Brien PC, Trenerry MR. Factors associated with work outcome after anterior temporal lobectomy for intractable epilepsy. Epilepsia. 1997 Jun; 38(6):689-95.
  136. Graff-Radford NR, Lin SC, Brazis PW, Bolling JP, Liesegang TJ, Lucas JA, Uitti RJ, O'Brien PC. Tropicamide eyedrops cannot be used for reliable diagnosis of Alzheimer's disease. Mayo Clin Proc. 1997 Jun; 72(6):495-504.
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  137. So EL, Radhakrishnan K, Silbert PL, Cascino GD, Sharbrough FW, O'Brien PC. Assessing changes over time in temporal lobectomy: outcome by scoring seizure frequency. Epilepsy Res. 1997 May; 27(2):119-25.
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  138. Beard CM, Kokmen E, O'Brien PC, Ania BJ, Melton LJ 3rd. Risk of Alzheimer's disease among elderly patients with anemia: population-based investigations in Olmsted County, Minnesota. Ann Epidemiol. 1997 Apr; 7(3):219-24.
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  139. Low PA, Opfer-Gehrking TL, Zimmerman IR, O'Brien PC. Evaluation of heart rate changes: electrocardiographic versus photoplethysmographic methods. Clin Auton Res. 1997 Apr; 7(2):65-8.
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  140. Engelstad JK, Davies JL, Giannini C, O'Brien PC, Dyck PJ. No evidence for axonal atrophy in human diabetic polyneuropathy. Journal of Neuropathology & Experimental Neurology. 1997 Mar; 56(3):255-62.
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  141. Leibson CL, Rocca WA, Hanson VA, Cha R, Kokmen E, O'Brien PC, Palumbo PJ. Risk of dementia among persons with diabetes mellitus: a population-based cohort study. Am J Epidemiol. 1997 Feb 15; 145(4):301-8.
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  142. Service FJ, Rizza RA, Zimmerman BR, Dyck PJ, O'Brien PC, Melton LJ 3rd. The classification of diabetes by clinical and C-peptide criteria. A prospective population-based study. Diabetes Care. 1997 Feb; 20(2):198-201.
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  143. Dyck PJ, Peroutka S, Rask C, Burton E, Baker MK, Lehman KA, Gillen DA, Hokanson JL, O'Brien PC. Intradermal recombinant human nerve growth factor induces pressure allodynia and lowered heat-pain threshold in humans. Neurology. 1997 Feb; 48(2):501-5.
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  144. Beard CM, Kokmen E, Sigler C, Smith GE, Petterson T, O'Brien PC. Cause of death in Alzheimer's disease. Ann Epidemiol. 1996 May; 6(3):195-200.
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  145. Kokmen E, Beard CM, O'Brien PC, Kurland LT. Epidemiology of dementia in Rochester, Minnesota. Mayo Clin Proc. 1996 Mar; 71(3):275-82.
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  146. Dyck PJ, Zimmerman IR, Johnson DM, Gillen D, Hokanson JL, Karnes JL, Gruener G, O'Brien PC. A standard test of heat-pain responses using CASE IV. J Neurol Sci. 1996 Mar; 136(1-2):54-63.
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  147. So EL, Annegers JF, Hauser WA, O'Brien PC, Whisnant JP. Population-based study of seizure disorders after cerebral infarction. Neurology. 1996 Feb; 46(2):350-5.
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  148. Kokmen E, Ozsarfati Y, Beard CM, O'Brien PC, Rocca WA. Impact of referral bias on clinical and epidemiological studies of Alzheimer's disease. J Clin Epidemiol. 1996 Jan; 49(1):79-83.
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  149. Kane LA, Service FJ, O'Brien PC, et al. Correlations of plasma concentrations of beta-cell polypeptides with pathological features of insulinomas Endocrine Practice. 1996; 2:1-3.
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  150. Safford RE, The Program Committee Florida Chapter American College of Cardiology. Coronary revascularization in the elderly: Florida multicenter consecutive case experience with coronary revascularization in patients age 75 years and older. Compr Ther. 1996; 22(8):477-484.
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  151. Chelimsky TC, Low PA, Naessens JM, Wilson PR, Amadio PC, O'Brien PC. Value of autonomic testing in reflex sympathetic dystrophy. Mayo Clin Proc. 1995 Nov; 70(11):1029-40.
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  152. Albers JW, Anderson H, Arezzo JC, Asbury A, Bolton C, Boulton AJM, Bril V, Brown M, Brownlee M, Canal N, Chalk C, Donaghy M, Dyck PJ, Feasby T, Giannini C, Goto Y, Grant I, Greene D, Griffin J, et al. Diabetic polyneuropathy in controlled clinical trials - consensus report of the Peripheral Nerve Society. Ann Neurol. 1995 Sep; 38:478-482.
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  153. Butkiewicz EK, Leibson CL, O'Brien PC, Palumbo PJ, Rizza RA. Insulin therapy for diabetic ketoacidosis. Bolus insulin injection versus continuous insulin infusion. Diabetes Care. 1995 Aug; 18(8):1187-90.
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  154. Low PA, Opfer-Gehrking TL, Dyck PJ, Litchy WJ, O'Brien PC. Double-blind, placebo-controlled study of the application of capsaicin cream in chronic distal painful polyneuropathy. Pain. 1995 Aug; 62(2):163-8.
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  155. Jack CR Jr, Trenerry MR, Cascino GD, Sharbrough FW, So EL, O'Brien PC. Bilaterally symmetric hippocampi and surgical outcome. Neurology. 1995 Jul; 45(7):1353-8.
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  156. Ahlskog JE, Waring SC, Kurland LT, Petersen RC, Moyer TP, Harmsen WS, Maraganore DM, O'Brien PC, Esteban-Santillan C, Bush V. Guamanian neurodegenerative disease: investigation of the calcium metabolism/heavy metal hypothesis. Neurology. 1995 Jul; 45(7):1340-4.
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  157. Dyck PJ, Litchy WJ, Lehman KA, Hokanson JL, Low PA, O'Brien PC. Variables influencing neuropathic endpoints: the Rochester Diabetic Neuropathy Study of Healthy Subjects. Neurology. 1995 Jun; 45(6):1115-21.
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  158. Rodriguez M, Siva A, Cross SA, O'Brien PC, Kurland LT. Optic neuritis: a population-based study in Olmsted County, Minnesota. Neurology. 1995 Feb; 45(2):244-50.
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  159. Beard CM, Kokmen E, O'Brien PC, Kurland LT. The prevalence of dementia is changing over time in Rochester, Minnesota. Neurology. 1995 Jan; 45(1):75-9.
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  160. O'Brien PC, Dyck PJ. Procedures for setting normal values. Neurology. 1995 Jan; 45(1):17-23.
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  161. Dyck PJ, Litchy WJ, Kratz KM, Suarez GA, Low PA, Pineda AA, Windebank AJ, Karnes JL, O'Brien PC. A plasma exchange versus immune globulin infusion trial in chronic inflammatory demyelinating polyradiculoneuropathy. Ann Neurol. 1994 Dec; 36(6):838-45.
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  162. Noseworthy JH, O'Brien PC, van Engelen BG, Rodriguez M. Intravenous immunoglobulin therapy in multiple sclerosis: progress from remyelination in the Theiler's virus model to a randomised, double-blind, placebo-controlled clinical trial. J Neurol Neurosurg Psychiatry. 1994 Nov; 57 Suppl:11-4.
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  163. Beard CM, Kokmen E, O'Brien PC, Kurland LT. Are patients with Alzheimer's disease surviving longer in recent years? Neurology. 1994 Oct; 44(10):1869-71.
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  164. Jack CR, Krecke KN, Luetmer PH, Cascino GD, Sharbrough FW, O'Brien PC, Parisi JE. Diagnosis of mesial temporal sclerosis with conventional versus fast spin-echo MR imaging. Radiology. 1994 Jul; 192(1):123-7.
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  165. Kokmen E, Ozekmekci FS, Beard CM, O'Brien PC, Kurland LT. Incidence and prevalence of Huntington's disease in Olmsted County, Minnesota (1950 through 1989). Arch Neurol. 1994 Jul; 51(7):696-8.
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  166. Jack CR Jr, Mullan BP, Sharbrough FW, Cascino GD, Hauser MF, Krecke KN, Luetmer PH, Trenerry MR, O'Brien PC, Parisi JE. Intractable nonlesional epilepsy of temporal lobe origin: lateralization by interictal SPECT versus MRI. Neurology. 1994 May; 44(5):829-36.
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  167. Waring SC, O'Brien PC, Kurland LT, Thibodeau SN, Tsai MS, Petersen RC, Estebansantillan CE. Apolipoprotein E allele in Chamorros with amyotrophic lateral sclerosis Parkinsonism-dementia complex. Lancet. 1994 Mar 5; 343:611.
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  168. Gough DB, Donohue JH, Schutt AJ, Gonchoroff N, Goellner JR, Wilson TO, Naessens JM, O'Brien PC, van Heerden JA. Pseudomyxoma peritonei. Long-term patient survival with an aggressive regional approach. Ann Surg. 1994 Feb; 219(2):112-9.
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  169. Ballard DJ, Bryant SC, O'Brien PC, Smith SC, Pine MB, Cortese DA. Referral selection bias in the medicare hospital mortality prediction model: are centers of referral for medicare beneficiaries necessarily centers of excellence? Health Serv Res. 1994 Feb; 28:6.
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  170. Rodriguez M, Siva A, Ward J, Stolp-Smith K, O'Brien P, Kurland L. Impairment, disability, and handicap in multiple sclerosis: a population-based study in Olmsted County, Minnesota. Neurology. 1994 Jan; 44(1):28-33.
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  171. Dinneen SF, Silverberg JD, Batts KP, O'Brien PC, Ballard DJ, Rizza RA. Liver iron stores in patients with non-insulin-dependent diabetes mellitus. Mayo Clin Proc. 1994 Jan; 69(1):13-5.
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  172. O'Brien PC. Discussion in: Deconstructing statistical questions by DJ Hand. J Royal Statistical Soc Series. 1994; A 35(157):350.
  173. O'Brien PC. Discussion. Stat Med. 1993 Dec 15; 12:2245-2246.
  174. Gough DB, Donohue JH, Evans MM, Pernicone PJ, Wold LE, Naessens JM, O'Brien PC. A 50-year experience of male breast cancer: is outcome changing? Surg Oncol. 1993 Dec; 2(6):325-33.
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  175. Thompson GB, Service FJ, van Heerden JA, Carney JA, Charboneau JW, O'Brien PC, Grant CS. Reoperative insulinomas, 1927 to 1992: an institutional experience. Surgery. 1993 Dec; 114(6):1196-204; discussion 1205-6.
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  176. Siva A, Radhakrishnan K, Kurland LT, O'Brien PC, Swanson JW, Rodriguez M. Trauma and multiple sclerosis: a population-based cohort study from Olmsted County, Minnesota. Neurology. 1993 Oct; 43(10):1878-82.
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  177. Kokmen E, Beard CM, O'Brien PC, Offord K, Kurland LT. Is the incidence of dementing illness changing? Neurology. 1993 Oct; 43:1887-1892.
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  178. Uitti RJ, Ahlskog JE, Maraganore DM, Muenter MD, Atkinson EJ, Cha RH, O'Brien PC. Levodopa therapy and survival in idiopathic Parkinson's disease: Olmsted County project. Neurology. 1993 Oct; 43(10):1918-26.
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  179. Cascino GD, So EL, Sharbrough FW, Strelow D, Lagerlund TD, Milde LN, O'Brien PC. Alfentanil-induced epileptiform activity in patients with partial epilepsy. J Clin Neurophysiol. 1993 Oct; 10(4):520-5.
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  180. O'Brien T, Dinneen SF, O'Brien PC, Palumbo PJ. Hyperlipidemia in patients with primary and secondary hypothyroidism. Mayo Clin Proc. 1993 Sep; 68(9):860-6.
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  181. Jensen MD, Kanaley JA, Roust LR, O'Brien PC, Braun JS, Dunn WL, Wahner HW. Assessment of body composition with use of dual-energy x-ray absorptiometry: evaluation and comparison with other methods. Mayo Clin Proc. 1993 Sep; 68(9):867-73.
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  182. Dyck PJ, Zimmerman I, Gillen DA, Johnson D, Karnes JL, O'Brien PC. Cool, warm, and heat-pain detection thresholds: testing methods and inferences about anatomic distribution of receptors. Neurology. 1993 Aug; 43(8):1500-8.
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  183. Dyck PJ, O'Brien PC, Kosanke JL, Gillen DA, Karnes JL. A 4, 2, and 1 stepping algorithm for quick and accurate estimation of cutaneous sensation threshold. Neurology. 1993 Aug; 43(8):1508-12.
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  184. O'Brien T, O'Brien PC, Service FJ. Insulin surrogates in insulinoma. J Clin Endocrinol Metab. 1993 Aug; 77(2):448-51.
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  185. Douglas DD, Rakela J, Lin HJ, Hollinger FB, Taswell HF, Czaja AJ, Gross JB, Anderson ML, Parent K, Fleming CR, et al. Randomized controlled trial of recombinant alpha-2a-interferon for chronic hepatitis C. Comparison of alanine aminotransferase normalization versus loss of HCV RNA and anti-HCV IgM. Dig Dis Sci. 1993 Apr; 38(4):601-7.
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  186. Butler PC, Caumo A, Zerman A, O'Brien PC, Cobelli C, Rizza RA. Methods for assessment of the rate of onset and offset of insulin action during nonsteady state in humans. Am J Physiol. 1993 Apr; 264(4 Pt 1):E548-60.
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  187. Dyck PJ, Kratz KM, Karnes JL, Litchy WJ, Klein R, Pach JM, Wilson DM, O'Brien PC, Melton LJ 3rd, Service FJ. The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: the Rochester Diabetic Neuropathy Study. Neurology. 1993 Apr; 43(4):817-24.
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  188. Melton LJ 3rd, Dyck PJ, Karnes JL, O'Brien PC, Service FJ. Non-response bias in studies of diabetic complications: the Rochester Diabetic Neuropathy Study. J Clin Epidemiol. 1993 Apr; 46(4):341-8.
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  189. Service FJ, O'Brien PC, McMahon MM, Kao PC. C-peptide during the prolonged fast in insulinoma. J Clin Endocrinol Metab. 1993 Mar; 76(3):655-9.
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  190. O'Brien T, Young WF Jr, Palumbo PJ, O'Brien PC, Service FJ. Hypertension and dyslipidemia in patients with insulinoma. Mayo Clin Proc. 1993 Feb; 68(2):141-6.
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  191. Kaplan J, Fredrickson PA, Renaux SA, O'Brien PC. Theophylline effect on sleep in normal subjects. Chest. 1993 Jan; 103(1):193-5.
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  192. O'Brien PC. A multivariate extension of von Neumann's ratio Communications in Statistics Theory and Methods. 1993; 23:239-48.
  193. Ory SJ, Nnadi E, Hermann RC Jr, O'Brien PC, Melton LJ. Fertility following ectopic pregnancy. Fertil Steril. 1993; 60:231-235.
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  194. O'Brien PC. Discussion on: Comparison of two tests useful in situations where treatment is expected to increase variability relative to controls, by Blair and Sawilowsky. Statistics in Medicine , 1993; 12:2245-6.
  195. Dyck PJ, Karnes JL, O'Brien PC, Litchy WJ, Low PA, Melton LJ 3rd. The Rochester Diabetic Neuropathy Study: reassessment of tests and criteria for diagnosis and staged severity. Neurology. 1992 Jun; 42(6):1164-70.
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  196. Jack CR, Sharbrough FW, Cascino GD, Hirschorn KA, O'Brien PC, Marsh WR. Magnetic resonance image-based hippocampal volumetry: correlation with outcome after temporal lobectomy. Ann Neurol. 1992 Feb; 31(2):138-46.
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  197. Service FJ, O'Brien PC, Kao PC, Young WF Jr. C-peptide suppression test: effects of gender, age, and body mass index; implications for the diagnosis of insulinoma. J Clin Endocrinol Metab. 1992 Jan; 74(1):204-10.
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  198. Fairbanks VF, Ziesmer SC, O'Brien PC. Methods for measuring plasma hemoglobin in micromolar concentration compared. Clin Chem. 1992 Jan; 38(1):132-40.
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  199. Cascino GD, Sharbrough FW, Jack CR Jr, Parisi JE, O'Brien PC. Acute depth electrode investigations in temporal lobe epilepsy: correlation with magnetic-resonance-imaging-based volume studies and pathology. J Epilepsy. 1992; 5(1):49-54.
  200. O'Brien PC. Commentary in: A clinical trial endpoint based on subjective rankings, by Follman D, Wittes J, Cutler JA. Statistics in Medicine , 1992; 11:447-9.
  201. O'Brien PC. Commentary in: On the use of the generalized t and generalized rank-sum statistics in medical research, by Blair RC and Morel, JG. Statistics in Medicine , 1992; 11:503-5.
  202. Jack CR, Petersen RC, O'Brien PC, Tangalos EG. MR-Based Hippocampal Volumetry in the Diagnosis of Alzheimer's Disease Neurology. 1992; 42(1):183-8.
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  203. O'Brien PC. Robust procedures for testing equality of covariance matrices Biometrics. 1992; 48:819-27.
  204. Armon C, Daube JR, O'Brien PC, Kurland LT, Mulder DW. When is an apparent excess of neurologic cases epidemiologically significant? Neurology. 1991 Nov; 41(11):1713-8.
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  205. Williams DB, Annegers JF, Kokmen E, O'Brien PC, Kurland LT. Brain injury and neurologic sequelae: a cohort study of dementia, parkinsonism, and amyotrophic lateral sclerosis. Neurology. 1991 Oct; 41(10):1554-7.
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  206. Patick AK, Thiemann RL, O'Brien PC, Rodriguez M. Persistence of Theiler's virus infection following promotion of central nervous system remyelination. Journal of Neuropathology & Experimental Neurology. 1991 Sep; 50(5):523-37.
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  207. Freeman WK, Schaff HV, O'Brien PC, Orszulak TA, Naessens JM, Tajik AJ. Cardiac surgery in the octogenarian: perioperative outcome and clinical follow-up. J Am Coll Cardiol. 1991 Jul; 18(1):29-35.
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  208. Service FJ, McMahon MM, O'Brien PC, Ballard DJ. Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study. Mayo Clin Proc. 1991 Jul; 66(7):711-9.
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  209. Armon C, Kurland LT, Daube JR, O'Brien PC. Epidemiologic correlates of sporadic amyotrophic lateral sclerosis. Neurology. 1991 Jul; 41(7):1077-84.
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  210. Cascino GD, Jack CR, Parisi JE, Sharbrough FW, Hirschorn KA, Meyer FB, Marsh WR, O'Brien PC. Magnetic resonance imaging-based volume studies in temporal lobe epilepsy: pathological correlations. Ann Neurol. 1991 Jul; 30(1):31-6.
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  211. Dyck PJ, Kratz KM, Lehman KA, Karnes JL, Melton LJ 3rd, O'Brien PC, Litchy WJ, Windebank AJ, Smith BE, Low PA. The Rochester Diabetic Neuropathy Study: design, criteria for types of neuropathy, selection bias, and reproducibility of neuropathic tests. Neurology. 1991 Jun; 41(6):799-807.
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  212. Stanhope CR, Wilson TO, Utz WJ, Smith LH, O'Brien PC. Suture entrapment and secondary ureteral obstruction. American Journal of Obstetrics & Gynecology. 1991 Jun; 164(6 Pt 1):1513-7; discussion 1517-9.
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  213. Gustavson CR, Gustavson JC, Noller KL, O'Brien PC, Melton LJ, Pumariega AJ, Kaufman RH, Colton T. Increased risk of profound weight loss among women exposed to diethylstilbestrol in utero. Behavioral & Neural Biology. 1991 May; 55(3):307-12.
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  214. Miller AR, van Heerden JA, Naessens JM, O'Brien PC. Simultaneous bilateral hernia repair. A case against conventional wisdom. Ann Surg. 1991 Mar; 213(3):272-6.
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  215. Armon C, Kurland LT, O'Brien PC, Mulder DW. Antecedent medical diseases in patients with amyotrophic lateral sclerosis. Arch Neurol. 1991 Mar; 48:283-286.
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  216. O'Brien PC. Commentary in: Multiple comparisons in over-the-counter drug clinical trials with both positive and placebo controls, by D'Agostino and Herren Stat in Med. 1991; 10:9-12.
  217. Grambsch PM, O'Brien PC. The effects of preliminary tests for non-linearity in regression Stat in Med. 1991; 10:697-710.
  218. Freeman SL, O'Brien PC, Rizza RA. Use of human ultralente as the basal insulin component in treatment of patients with IDDM Diabetes Res and Clin Pracice. 1991; 12:187-92.
  219. Armon C, Kurland LT, Beard CM, O'Brien PC, et al Psychological and adaptational difficulties anteceding amyotrophic lateral sclerosis: Rochester, Minnesota, 1925-1987 Neuroepidemiology. 1991; 10:132-7.
  220. O'Brien PC, Tilley B, Meier P, et al. Selection bias in observational studies: An example from the Diethylstilbestrol Project Clin Practice of Gyn. 1991; 2:109-25.
  221. Davis KP, Stanhope CR, Garton GR, Atkinson EJ, O'Brien PC. Invasive vaginal carcinoma: Analysis of early-stage disease. Gynecol Oncol. 1991; 42:131-6.
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  222. Lavine L, Steele JC, Wolfe N, Calne DB, O'Brien PC, Williams DB, Kurland LT, Schoenberg BS. Amyotrophic lateral sclerosis/parkinsonism-dementia complex in southern Guam: is it disappearing? Adv Neurol. 1991; 56:271-85.
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  223. Safranek TJ, Lawrence DN, Kurland LT, Culver DH, Wiederholt WC, Hayner NS, Osterholm MT, O'Brien P, Hughes JM. Measurement of the association between Guillian-Barré syndrome and receipt of swine influenza vaccine in 1976-1977: Results of a two-state study. American Journal of Epidemiology 133-***********.
  224. Khosla S, Johansen KL, Ory SJ, O'Brien PC, Kao PC. Parathyroid hormone-related peptide in lactation and in umbilical cord blood. Mayo Clin Proc. 1990 Nov; 65(11):1408-14.
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  225. Popescu NA, Beard CM, Treacy PJ, Winkelmann RK, O'Brien PC, Kurland LT. Cutaneous malignant melanoma in Rochester, Minnesota: trends in incidence and survivorship, 1950 through 1985. Mayo Clin Proc. 1990 Oct; 65(10):1293-302.
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  226. Rakela J, Wood JR, Czaja AJ, O'Brien PC, Taswell HF, Bowyer BA, Lange SM, Anderson ML, Parent K. Long-term versus short-term treatment with recombinant interferon alfa-2a in patients with chronic hepatitis B: a prospective, randomized treatment trial. Mayo Clin Proc. 1990 Oct; 65(10):1330-5.
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  227. Dyck PJ, Karnes JL, Gillen DA, O'Brien PC, Zimmerman IR, Johnson DM. Comparison of algorithms of testing for use in automated evaluation of sensation. Neurology. 1990 Oct; 40(10):1607-13.
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  228. Johnson WJ, Kyle RA, Pineda AA, O'Brien PC, Holley KE. Treatment of renal failure associated with multiple myeloma. Plasmapheresis, hemodialysis, and chemotherapy. Arch Intern Med. 1990 Apr; 150(4):863-9.
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  229. Wilson TO, Podratz KC, Gaffey TA, Malkasian GD, O'Brien PC, Naessens JM. Evaluation of unfavorable histologic subtypes in endometrial adenocarcinoma. American Journal of Obstetrics & Gynecology. 1990 Feb; 162(2):418-23; discussion 423-6.
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  230. Ingall TJ, McLeod JG, O'Brien PC. The effect of aging on autonomic nervous system function Aust NZ J Med. 1990; 20:570-7.
  231. McMahon MM, O'Brien PC, Service FJ. Diagnostic interpretation of the intravenous tolbutamide test for insulinoma. Mayo Clin Proc. 1989 Dec; 64(12):1481-8.
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  232. Dyck PJ, O'Brien PC. Meaningful degrees of prevention or improvement of nerve conduction in controlled clinical trials of diabetic neuropathy. Diabetes Care. 1989 Oct; 12(9):649-52.
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  233. Nielsen SN, Podratz KC, Scheithauer BW, O'Brien PC. Clinicopathologic analysis of uterine malignant mixed mullerian tumors. Gynecol Oncol. 1989 Sep; 34(3):372-8.
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  234. Dyck PJ, Minnerath SR, O'Brien PC. Nerve glucose, sorbitol, fructose, and myo-inositol at various time after feeding in streptozotocin-induced diabetes in rats. Mayo Clin Proc. 1989 Aug; 64(8):905-10.
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  235. Davis LJ, de la Fuente JR, Morse RM, Landa E, O'Brien PC. Self-administered alcoholism screening test (SAAST): comparison of classificatory accuracy in two cultures. Alcoholism: Clinical & Experimental Research. 1989 Apr; 13(2):224-8.
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  236. O'Brien PC. Discussion in: Interim analyses: The repeated confidence interval approach by Jennison and Turnbull. J Royal Statistical Soc. 1989; 51:349.
  237. O'Brien PC, Shampo MA, Dyck PJ. Statistical analysis in clinical laboratory medicine: fundamentals and common uses. Crit Rev Clin Lab Sci. 1989; 27(4):319-40.
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  238. O'Brien PC, Shampo MA. Statistical considerations for performing multiple tests in a single experiment. 6. Testing accumulating data repeatedly over time. Mayo Clin Proc. 1988 Dec; 63(12):1245-50.
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  239. O'Brien PC, Shampo MA. Statistical considerations for performing multiple tests in a single experiment. 5. Comparing two therapies with respect to several endpoints. Mayo Clin Proc. 1988 Nov; 63(11):1140-3.
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  240. O'Brien PC, Shampo MA. Statistical considerations for performing multiple tests in a single experiment. 4. Performing multiple statistical tests on the same data. Mayo Clin Proc. 1988 Oct; 63(10):1043-5.
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  241. Wilson SE, Bourne WM, O'Brien PC, Brubaker RF. Endothelial function and aqueous humor flow rate in patients with Fuchs' dystrophy. Am J Ophthalmol. 1988 Sep 15; 106(3):270-8.
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  242. O'Brien PC, Shampo MA. Statistical considerations for performing multiple tests in a single experiment. 3. Repeated measures over time. Mayo Clin Proc. 1988 Sep; 63(9):918-20.
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  243. Shuster LT, Go VL, Rizza RA, O'Brien PC, Service FJ. Potential incretins. Mayo Clin Proc. 1988 Aug; 63(8):794-800.
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  244. O'Brien PC, Shampo MA. Statistical considerations for performing multiple tests in a single experiment. 1. Introduction. Mayo Clin Proc. 1988 Aug; 63(8):813-5.
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  245. O'Brien PC, Shampo MA. Statistical considerations for performing multiple tests in a single experiment. 2. Comparisons among several therapies. Mayo Clin Proc. 1988 Aug; 63(8):816-20.
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  246. Noller KL, Blair PB, O'Brien PC, Melton LJ 3rd, Offord JR, Kaufman RH, Colton T. Increased occurrence of autoimmune disease among women exposed in utero to diethylstilbestrol. Fertil Steril. 1988 Jun; 49(6):1080-2.
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  247. Roust LR, Stesin M, Go VL, O'Brien PC, Rizza RA, Service FJ. Role of gastric inhibitory polypeptide in postprandial hyperinsulinemia of obesity. Am J Physiol. 1988 Jun; 254(6 Pt 1):E767-74.
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  248. Nora JD, Hallett JW Jr, O'Brien PC, Naessens JM, Cherry KJ Jr, Pairolero PC. Surgical resection of carotid body tumors: long-term survival, recurrence, and metastasis. Mayo Clin Proc. 1988 Apr; 63(4):348-52.
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  249. Vukov LF, White RD, Bachman JW, O'Brien PC. New perspectives on rural EMT defibrillation. Ann Emerg Med. 1988 Apr; 17(4):318-21.
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  250. Jedd MB, Melton LJ 3rd, Griffin MR, Kaufman BH, Hoffman AD, Broughton DD, O'Brien PC. Trends in infantile hypertrophic pyloric stenosis in Olmsted County, Minnesota, 1950-1984. Paediatric & Perinatal Epidemiology. 1988 Apr; 2(2):148-57.
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  251. Jedd MB, Melton LJ 3rd, Griffin MR, Kaufman B, Hoffman AD, Broughton D, O'Brien PC. Factors associated with infantile hypertrophic pyloric stenosis. Am J Dis Child. 1988 Mar; 142(3):334-7.
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  252. Shuster LT, Go VL, Rizza RA, O'Brien PC, Service FJ. Incretin effect due to increased secretion and decreased clearance of insulin in normal humans. Diabetes. 1988 Feb; 37(2):200-3.
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  253. Plate G, Hollier LH, O'Brien PC, Pairolero PC, Cherry KJ. Late cerebrovascular accidents after repair of abdominal aortic aneurysms. Acta Chir Scand. 1988 Jan; 154(1):25-9.
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  254. O'Brien PC. Comparing two samples: Extensions of the T, rank sum, and log rank tests J Am Statistical Assn. 1988; 83:52-61.
  255. Dyck PJ, Bushek W, Spring EM, Karnes JL, Litchy WJ, O'Brien PC, Service FJ. Vibratory and cooling detection thresholds compared with other tests in diagnosing and staging diabetic neuropathy. Diabetes Care. 1987 Jul-Aug; 10(4):432-40.
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  256. Dyck PJ, Classen SM, Stevens JC, O'Brien PC. Assessment of nerve damage in the feet of long-distance runners. Mayo Clin Proc. 1987 Jul; 62(7):568-72.
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  257. Noller KL, O'Brien PC, Melton LJ, Offord JR, Richart RM, Robboy SJ, Kaufman RH. Coital risk factors for cervical cancer: sexual activity among. Am J Clin Oncol. 1987 Jun; 10:222-226.
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  258. Davis LJ, Hurt RD, Morse RM, O'Brien PC. Discriminant analysis of the Self-Administered Alcoholism Screening Test. Alcoholism: Clinical & Experimental Research. 1987 Jun; 11(3):269-73.
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  259. Benson RC, Gorman PA, O'Brien PC, Holicky EL, Veneziale CM. Relationship between androgen receptor binding activity in human prostate cancer and clinical response to endocrine therapy. Cancer. 1987 May 1; 59(9):1599-606.
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  260. Hallett JW, Fowl R, O'Brien PC, Bernatz PE, Pairolero PC, Cherry KJ, Hollier LH. Renovascular operations in patients with chronic renal insufficiency: do the benefits justify the risks? J Vasc Surg. 1987 Apr; 5(4):622-7.
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  261. Service FJ, O'Brien PC, Rizza RA. Measurements of glucose control. Diabetes Care. 1987 Mar-Apr; 10(2):225-37.
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  262. Lumpkin MM, Smith TF, Coulam CB, O'Brien PC. Ureaplasma urealyticum in semen for artificial insemination: its effect on conception and semen analysis parameters. Int J Fertil. 1987 Mar/Apr; 32:122-30.
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  263. Stewart JM, Houser OW, Baker HL, O'Brien PC, Rodriguez M. Magnetic resonance imaging and clinical relationships in multiple sclerosis. Mayo Clin Proc. 1987 Mar; 62(3):174-84.
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  264. Reigel MM, Hollier LH, Kazmier FJ, O'Brien PC, Pairolero PC, Cherry KJ, Hallett JW. Late survival in abdominal aortic aneurysm patients: the role of selective myocardial revascularization on the basis of clinical symptoms. J Vasc Surg. 1987 Feb; 5(2):222-7.
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  265. O'Brien PC, Fleming TR. A paired Wilcoxon test for censored paired data. Biometrics. 1987; 43:169-80.
  266. O'Brien PC, Shampo MA, Anderson CF. Statistics in nutrition, Part 5: Survivorship studies. Nutrition International. 1987; 3:61-4.
  267. O'Brien PC, Shampo MA, Anderson CF. Stistics in nutrition, Part 6: Normal values, evaluating a new procedure, sequential methods, and conclusion. Nutrition International. 1987; 3:130-5.
  268. Noller KN, O'Brien PC, Melton LJ, et al. Risk factors for cervical cancer: Sexual activity among white middle class women. Am J of Clinical Trials 10222-226, 1987; Oncology:Cancer Clinical.
  269. Dyck PJ, Karnes J, O'Brien PC, Swanson CJ. Neuropathy Symptom Profile in health, motor neuron disease, diabetic neuropathy, and amyloidosis. Neurology. 1986 Oct; 36(10):1300-8.
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  270. Stanhope CR, Symmonds RE, Lee RA, Williams TJ, Podratz KC, O'Brien PC. Urinary diversion with use of ileal and sigmoid conduits. American Journal of Obstetrics & Gynecology. 1986 Aug; 155(2):288-92.
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  271. Bachman JW, McDonald GS, O'Brien PC. A study of out-of-hospital cardiac arrests in northeastern Minnesota. JAMA. 1986 Jul 25; 256(4):477-83.
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  272. Podratz KC, Podczaski ES, Gaffey TA, O'Brien PC, Schray MF, Malkasian GD. Primary carcinoma of the fallopian tube. American Journal of Obstetrics & Gynecology. 1986 Jun; 154(6):1319-26.
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  273. Dyck PJ, Karnes JL, O'Brien P, Okazaki H, Lais A, Engelstad J. The spatial distribution of fiber loss in diabetic polyneuropathy suggests ischemia. Ann Neurol. 1986 May; 19(5):440-9.
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  274. Pach JM, Robertson DM, Taney BS, Martin JA, Campbell RJ, O'Brien PC. Prognostic factors in choroidal and ciliary body melanomas with extrascleral extension. Am J Ophthalmol. 1986 Mar 15; 101(3):325-31.
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  275. Hill LM, Breckle R, Wolfgram KR, O'Brien PC. Evaluation of three methods for estimating fetal weight. J Clin Ultrasound. 1986 Mar-Apr; 14(3):171-8.
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  276. Chang MN, O'Brien PC. Confidence intervals following group sequential tests. Control Clin Trials. 1986 Mar; 7(1):18-26.
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  277. Rizza RA, O'Brien PC, Service FJ. Use of beef ultralente for basal insulin delivery: plasma insulin concentrations after chronic ultralente administration in patients with IDDM. Diabetes Care. 1986 Mar-Apr; 9(2):120-3.
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  278. Service FJ, Jay JM, Rizza RA, O'Brien PC, Go VL. Neurotensin in diabetes and obesity. Regul Pept. 1986 Mar; 14(1):85-92.
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  279. Zachariah PK, Sheps SG, Schirger A, Spiekerman RE, O'Brien PC, Simpson KK. Verapamil and 24-hour ambulatory blood pressure monitoring in essential hypertension. Am J Cardiol. 1986 Feb 26; 57(7):74D-79D.
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  280. Dyck PJ, Daube J, O'Brien P, Pineda A, Low PA, Windebank AJ, Swanson C. Plasma exchange in chronic inflammatory demyelinating polyradiculoneuropathy. N Engl J Med. 1986 Feb 20; 314(8):461-5.
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  281. Dyck PJ, Lais A, Karnes JL, O'Brien PC, Rizza RA. Fiber loss is primary and multifocal in sural nerves in diabetic polyneuropathy suggests ischemia. Ann Neurol. 1986; 19:425-439.
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  282. O'Brien PC, Shampo MA, Anderson CF. Statistics in nutrition, Part 1: Introduction, descriptive statistics, and graphic displays. Nutrition International. 1986; 2:167-71.
  283. O'Brien PC, Shampo MA, Anderson CF. Statistics in nutrition: Part 2, Estimation from samples and t tests. Nutritional International. 1986; 2:119-24.
  284. O'Brien PC, Shampo MA, Anderson CF. Statistics in nutrition, Part 3: A. Comparing two proportions (the relative deviate test and chi-square equivalent) B. Common types of studies. Nutrition International. 1986; 2:188-91.
  285. O'Brien PC, Shampo MA, Anderson CF. Statistics in nutrition, Part 4: Regression. Nutritional International. 1986; 2:331-3.
  286. O'Brien PC, Fleming TR. Procedures for censored paired survival data. Proceedings of the International Biometric Conference, 1986.
  287. Vukov LF, White RD, Bachman JW, O'Brien PC. Automated external defibrillation in rural Southeastern Minnesota communities. Am J Emerg Med. 1986; 4:423-4.
  288. Nelson JK, Palumbo PJ, O'Brien PC. Home enteral nutrition: observations of a newly established program. Nutr Clin Pract. 1986; 1(4):193-9.
  289. Dyck PJ, Karnes JL, Daube J, O'Brien P, Service FJ. Clinical and neuropathological criteria for the diagnosis and staging of diabetic polyneuropathy. Brain. 1985 Dec; 108(Pt 4):861-80.
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  290. Service FJ, Rizza RA, Daube JR, O'Brien PC, Dyck PJ. Near normoglycaemia improved nerve conduction and vibration sensation in diabetic neuropathy. Diabetologia. 1985 Oct; 28(10):722-7.
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  291. Jones CA, Tsukamoto T, O'Brien PC, Uhl CB, Alley MC, Lieber MM. Soft agarose culture human tumour colony forming assay for drug sensitivity testing: [3H]-thymidine incorporation vs colony counting. Br J Cancer. 1985 Sep; 52(3):303-10.
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  292. Hill LM, Breckle R, Gehrking WC, O'Brien PC. Use of femur length in estimation of fetal weight. American Journal of Obstetrics & Gynecology. 1985 Aug 1; 152(7 Pt 1):847-52.
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  293. Dyck PJ, O'Brien P, Swanson C, Low P, Daube J. Combined azathioprine and prednisone in chronic inflammatory-demyelinating polyneuropathy. Neurology. 1985 Aug; 35(8):1173-6.
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  294. Podratz KC, O'Brien PC, Malkasian GD Jr, Decker DG, Jefferies JA, Edmonson JH. Effects of progestational agents in treatment of endometrial carcinoma. Obstetrics & Gynecology. 1985 Jul; 66(1):106-10.
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  295. Welch WR, Robboy SJ, Kaufman RH, Townsend D, Noller KL, Gundersen J, Lawrence WD, Richart RM, O'Brien P, McGorray S, et al. Pathology of colposcopic findings in 2635 diethylstilbestrol-exposed young women. Gynecol Oncol. 1985 Jul; 21(3):277-86.
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  296. Plate G, Hollier LA, O'Brien P, Pairolero PC, Cherry KJ, Kazmier FJ. Recurrent aneurysms and late vascular complications following repair of abdominal aortic aneurysms. Arch Surg. 1985 May; 120(5):590-4.
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  297. Dyck PJ, Hansen S, Karnes J, O'Brien P, Yasuda H, Windebank A, Zimmerman B. Capillary number and percentage closed in human diabetic sural nerve. Proc Natl Acad Sci U S A. 1985 Apr; 82(8):2513-7.
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  298. O'Brien PC, Dyck PJ. A runs test based on run lengths. Biometrics. 1985 Mar; 41(1):237-44.
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  299. Sheps SG, Schirger A, Spiekerman RE, Harman TR, O'Brien PC, Kleven MK, Kremer-Simpson K. Evaluation of pindolol dosage in hypertension by automatic indirect BP monitoring. Arch Intern Med. 1985 Jan; 145(1):54-7.
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  300. Monzon CM, Fairbanks VF, Burgert EO Jr, O'Brien PC, Sutherland JE, Elliot SC. Height and weight of Southeast Asian refugee children. Nutr Res. 1985; 5:685-692.
  301. Leary FJ, Resseguie LJ, Kurland LT, O'Brien PC, Emslander RF, Noller KL. Males exposed in utero to diethylstilbestrol. JAMA. 1984 Dec 7; 252(21):2984-9.
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  302. Robboy SJ, Noller KL, O'Brien P, Kaufman RH, Townsend D, Barnes AB, Gundersen J, Lawrence WD, Bergstrahl E, McGorray S. Increased incidence of cervical and vaginal dysplasia in 3,980 diethylstilbestrol-exposed young women. Experience of the National Collaborative Diethylstilbestrol Adenosis Project. JAMA. 1984 Dec 7; 252(21):2979-83.
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  303. Fleming TR, Harrington DP, O'Brien PC. Designs for group sequential tests. Control Clin Trials. 1984 Dec; 5:348-361.
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  304. Dyck PJ, Karnes J, O'Brien PC, Nukada H, Lais A, Low PA. Spatial pattern of nerve fiber abnormality indicative of pathologic mechanisms. Am J Pathol. 1984 Nov; 117:225-238.
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  305. Zimmer WD, Williamson B Jr, Hartman GW, Hattery RR, O'Brien PC. Changing patterns in the evaluation of renal masses: economic implications. AJR Am J Roentgenol. 1984 Aug; 143(2):285-9.
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  306. Malkasian GD, Melton LJ 3rd, O'Brien PC, Greene MH. Prognostic significance of histologic classification and grading of epithelial malignancies of the ovary. American Journal of Obstetrics & Gynecology. 1984 Jun 1; 149(3):274-84.
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  307. Wallin TE, Malkasian GD Jr, Gaffey TA, O'Brien PC, Fountain KS. Stage II cancer of the endometrium: a pathologic and clinical study. Gynecol Oncol. 1984 May; 18(1):1-17.
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  308. Lee DA, Dyer JA, O'Brien PC, Taylor JZ. Surgical treatment of lateral rectus muscle paralysis. Am J Ophthalmol. 1984 Apr; 97(4):511-8.
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  309. Trastek VF, Pairolero PC, Piehler JM, Weiland LH, O'Brien PC, Payne WS, Bernatz PE. En bloc (non-chest wall) resection for bronchogenic carcinoma with parietal fixation. Factors affecting survival. J Thorac Cardiovasc Surg. 1984 Mar; 87(3):352-8.
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  310. Hollier LH, Plate G, O'Brien PC, Kazmier FJ, Gloviczki P, Pairolero PC, Cherry KJ. Late survival after abdominal aortic aneurysm repair: influence of coronary artery disease. J Vasc Surg. 1984 Mar; 1(2):290-9.
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  311. Jefferies JA, Robboy SJ, O'Brien PC, Bergstralh EJ, Labarthe DR, Barnes AB, Noller KL, Hatab PA, Kaufman RH, Townsend DE. Structural anomalies of the cervix and vagina in women enrolled in the Diethylstilbestrol Adenosis (DESAD) Project. American Journal of Obstetrics & Gynecology. 1984 Jan 1; 148(1):59-66.
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  312. Leary FJ, Resseguie LJ, Kurland LT, O'Brien PC, et al. Evaluation of males exposed in utero to diethylstilbestrol. Journal of the American Medical Association. 1984; 252:2984-9.
  313. O'Brien PC. Procedures for comparing samples with multiple endpoints Biometrics. 1984; 40:1079-88.
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  314. Hall S, Persellin S, Lie JT, O'Brien PC, Kurland LT, Hunder GG. The therapeutic impact of temporal artery biopsy. Lancet. 1983 Nov 26; 2(8361):1217-20.
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  315. Service FJ, Rizza RA, Hall LD, Westland RE, O'Brien PC, Clemens AH, Haymond MW, Gerich JE. Prandial insulin requirements in insulin-dependent diabetics: effects of size, time of day, and sequence of meals. Journal of Clinical Endocrinology & Metabolism. 1983 Nov; 57(5):931-6.
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  316. Hill LM, Breckle R, Wolfgram KR, O'Brien PC. Oligohydramnios: ultrasonically detected incidence and subsequent fetal outcome. American Journal of Obstetrics & Gynecology. 1983 Oct 15; 147(4):407-10.
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  317. Service FJ, Hall LD, Westland RE, O'Brien PC, Go VL, Haymond MW, Rizza RA. Effects of size, time of day and sequence of meal ingestion on carbohydrate tolerance in normal subjects. Diabetologia. 1983 Oct; 25(4):316-21.
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  318. Podratz KC, Gaffey TA, Symmonds RE, Johansen KL, O'Brien PC. Melanoma of the vulva: an update. Gynecol Oncol. 1983 Oct; 16(2):153-68.
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  319. O'Brien PC. The appropriateness of analysis of variance and multiple-comparison procedures. Biometrics. 1983 Sep; 39:787-794.
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  320. Newcomer AD, Park HS, O'Brien PC, McGill DB. Response of patients with irritable bowel syndrome and lactase deficiency using unfermented acidophilus milk. Am J Clin Nutr. 1983 Aug; 38(2):257-63.
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  321. Dyck PJ, Karnes JL, Windebank AJ, Sparks M, Stevens JC, O'Brien PC. Minimal pathologic expression of a mutant gene for hereditary motor and sensory neuropathy. Mayo Clin Proc. 1983 Jul; 58(7):419-25.
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  322. Noller KL, Townsend DE, Kaufman RH, Barnes AB, Robboy SJ, Fish CR, Jefferies JA, Bergstralh EJ, O'Brien PC, McGorray SP, Scully R. Maturation of vaginal and cervical epithelium in women exposed in utero to diethylstilbestrol (DESAD Project). American Journal of Obstetrics & Gynecology. 1983 Jun 1; 146(3):279-85.
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  323. O'Brien PC, Shampo MA, Robertson JS. Statistics for nuclear medicine. Part 6: Normal values, evaluating a new diagnostic procedure, sequential methods, and conclusion. J Nucl Med. 1983 Jun; 24(6):535-41.
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  324. Hill LM, Breckle R, Ragozzino MW, Wolfgram KR, O'Brien PC. Grade 3 placentation: incidence and neonatal outcome. Obstetrics & Gynecology. 1983 Jun; 61(6):728-32.
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  325. O'Brien PC, Shampo MA, Robertson JS. Statistics for nuclear medicine. Part 5: Survivorship studies. J Nucl Med. 1983 May; 24(5):444-6.
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  326. Service FJ, Daube JR, O'Brien PC, Zimmerman BR, Swanson CJ, Brennan MD, Dyck PJ. Effect of blood glucose control on peripheral nerve function in diabetic patients. Mayo Clin Proc. 1983 May; 58(5):283-9.
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  327. O'Brien PC, Shampo MA, Robertson JS. Statistics for nuclear medicine. Part 4: Regression. J Nucl Med. 1983 Apr; 24(4):363-5.
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  328. O'Brien PC, Shampo MA, Robertson JS. Statistics for nuclear medicine. Part 3: A. Comparing two proportions (the relative deviate test and chi-square equivalent). B. Counting data. J Nucl Med. 1983 Mar; 24(3):269-72.
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  329. Dyck PJ, Stevens JC, O'Brien PC, Oviatt KF, Lais AC, Coventry MB, Beabout JW. Neurogenic arthropathy and recurring fractures with subclinical inherited neuropathy. Neurology. 1983 Mar; 33(3):357-67.
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  330. O'Brien PC, Shampo MA, Robertson JS. Statistics for nuclear medicine. Part 2: Estimation from samples and t-tests. J Nucl Med. 1983 Feb; 24(2):165-71.
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  331. O'Brien PC, Shampo MA, Robertson JS. Statistics for nuclear medicine. Introduction, descriptive statistics, and graphic displays. J Nucl Med. 1983 Jan; 24(1):83-8.
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  332. Dyck PJ, Karnes J, Bushek W, Spring E, O'Brien PC. Computer assisted sensory examination to detect and quantitate sensory deficity in diabetic neuropathy. Neurobehav Toxicol Teratol. 1983; 5:697-704.
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  333. Dyck PJ, O'Brien PC, Oviatt KF, Dinapoli RP, Daube JR, Bartleson JD, Mokri B, Swift T, Low PA, Windebank AJ. Prednisone improves chronic inflammatory demyelinating polyradiculoneuropathy more than no treatment. Ann Neurol. 1982 Feb; 11(2):136-41.
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  334. O'Brien PC, Shampo MA. Statistics for clinicians. 12. Sequential methods. Mayo Clin Proc. 1981 Dec; 56(12):753-4.
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  335. O'Brien PC, Shampo MA. Statistics for physicians: epilogue. Mayo Clin Proc. 1981 Dec; 56:755-756.
  336. Kelly JJ Jr, Kyle RA, O'Brien PC, Dyck PJ. Prevalence of monoclonal protein in peripheral neuropathy. Neurology. 1981 Nov; 31(11):1480-3.
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  337. Service FJ, Daube JR, O'Brien PC, Dyck PJ. Effect of artificial pancreas treatment on peripheral nerve function in diabetes. Neurology. 1981 Nov; 31(11):1375-80.
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  338. O'Brien PC, Shampo MA. Statistics for clinicians. 11. Survivorship studies. Mayo Clin Proc. 1981 Nov; 56(11):709-11.
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  339. O'Brien PC, Shampo MA. Statistics for clinicians: 10. normal values. Mayo Clin Proc. 1981 Oct; 56:639-640.
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  340. O'Brien PC, Shampo MA. Statistics for clinicians. 9. Evaluating a new diagnostic procedure. Mayo Clin Proc. 1981 Sep; 56(9):573-5.
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  341. O'Brien PC, Shampo MA. Statistics for clinicians. 8. Comparing two proportions: the relative deviate test and chi-square equivalent. Mayo Clin Proc. 1981 Aug; 56(8):513-5.
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  342. Pittelkow MR, Perry HO, Muller SA, Maughan WZ, O'Brien PC. Skin cancer in patients with psoriasis treated with coal tar. A 25-year follow-up study. Arch Dermatol. 1981 Aug; 117(8):465-8.
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  343. O'Brien PC, Shampo MA. Statistics for clinicians. 7. Regression. Mayo Clin Proc. 1981 Jul; 56(7):452-4.
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  344. O'Brien PC, Shampo MA. Statistics for clinicians. 6. comparing two samples. the two-sample t test. Mayo Clin Proc. 1981 Jun; 56:393-394.
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  345. O'Brien PC, Shampo MA. Statistics for clinicians. 5. One sample of paired observations (paired t test). Mayo Clin Proc. 1981 May; 56(5):324-6.
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  346. O'Brien PC, Shampo MA. Statistics for clinicians. 4. estimation from samples. Mayo Clin Proc. 1981 Apr; 56:274-276.
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  347. O'Brien PC, Shampo MA. Statistics for clinicians: 3. graphic displays--scatter diagrams. Mayo Clin Proc. 1981 Mar; 56:196-197.
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  348. O'Brien PC, Shampo MA. Graphic displays--histograms, frequency polygons, and cumulative distribution polygons. Mayo Clin Proc. 1981 Feb; 56:126-128.
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  349. O'Brien PC, Shampo MA. Statistics for clinicians: introduction. Mayo Clin Proc. 1981 Jan; 56:45-46.
  350. O'Brien PC, Shampo MA. Statistics for clinicians. 1. Descriptive statistics. Mayo Clin Proc. 1981 Jan; 56(1):47-9.
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  351. Kelly JJ Jr, Kyle RA, Miles JM, O'Brien PC, Dyck PJ. The spectrum of peripheral neuropathy in myeloma. Neurology. 1981 Jan; 31(1):24-31.
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  352. Maughan WZ, Muller SA, Perry HO, Pittelkow MR, O'Brien PC. Incidence of skin cancers in patients with atopic dermatitis treated with coal tar: a 25-year follow-up study. J Am Acad Dermatol. 1980 Dec; 3:612-615.
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  353. Dyck PJ, Sherman WR, Hallcher LM, Service FJ, O'Brien PC, Grina LA, Palumbo PJ, Swanson CJ. Human diabetic endoneurial sorbitol, fructose, and myo-inositol related to sural nerve morphometry. Ann Neurol. 1980 Dec; 8(6):590-6.
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  354. St John Sutton MG, Lie JT, Anderson KR, O'Brien PC, Frye RL. Histopathological specificity of hypertrophic obstructive cardiomyopathy. Myocardial fibre disarray and myocardial fibrosis. Br Heart J. 1980 Oct; 44(4):433-43.
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  355. Zimmerman IR, Karnes JL, O'Brien PC, Dyck PJ. Imaging system for nerve and fiber tract morphometry: components, approaches, performance, and results. Journal of Neuropathology & Experimental Neurology. 1980 Jul; 39(4):409-19.
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  356. Barnes AB, Colton T, Gundersen J, Noller KL, Tilley BC, Strama T, Townsend DE, Hatab P, O'Brien PC. Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol. Obstet Gynecol Surv. 1980 Jul; 35:471-473.
  357. Barnes AB, Colton T, Gunderson J, Noller KL, Tilley BC, Strama T, Townsend DE, Hatab P, O'Brien PC. Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol. N Engl J Med. 1980 Mar 13; 302:609-613.
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  358. Maruta T, Swanson DW, O'Brien PC. Response to letter to editor of A. H. Roberts, commenting on chronic pain. Pain. 1980; 9:277-278.
  359. O'Brien PC. A likelihood test for multivariate serial correlation. Biometrika. 1980; 67(3):531-7.
  360. Fleming TR, O'Fallon JR, O'Brien PC, Harrington DP. Modified Kolmogorov-Smirnov test procedures with application to arbitrarily right censored data Biometrics. 1980; 36:607-625.
  361. Fleming TR, O'Fallon JR, O'Brien PC, Harrington DP. Smirnov two-sample test procedures generalized to arbitrarily right censored data. Biometrics, 36:607-635, 1980.
  362. Dyck PJ, Johnson WJ, Lambert EH, O'Brien PC, Daube JR, Oviatt KF. Comparison of symptoms, chemistry, and nerve function to assess adequacy of hemodialysis. Neurology. 1979 Oct; 29(10):1361-8.
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  363. Dyck PJ, Jedrzejowska H, Karnes J, Kawamura Y, Low PA, O'Brien PC, Offord K, Ohnishi A, Ohta M, Pollock M, Stevens JC. Reconstruction of motor, sensory, and autonomic neurons based on morphometric study of sampled levels. Muscle & Nerve. 1979 Sep-Oct; 2(5):399-405.
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  364. Kelly JJ Jr, Kyle RA, O'Brien PC, Dyck PJ. The natural history of peripheral neuropathy in primary systemic amyloidosis. Ann Neurol. 1979 Jul; 6(1):1-7.
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  365. O'Brien PD, Noller KL, Robboy SJ, Barnes AB, Kaufman RH, Tilley BC, Townsend DE. Vaginal epithelial changes in young women enrolled in the national cooperative diethylstilbestrol adenosis (DESAD) project. Obstet Gynecol. 1979 Mar; 53:300-308.
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  366. Hasegawa M, Kern EB, O'Brien PC. Dynamic changes of nasal resistance. Annals of Otology, Rhinology & Laryngology. 1979 Jan-Feb; 88(1 Pt 1):66-71.
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  367. O'Brien PC, Fleming TR. A multiple testing procedure for clinical trials. Biometrics. 1979; 35:549-56.
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  368. Mathew GD, Facer GW, Suh KW, Houser OW, O'Brien PC. Symptoms, findings, and methods of diagnosis in patients with acoustic neuroma. Laryngoscope. 1978 Dec; 88(12):1893-903, 1921.
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  369. Dyck PJ, Zimmerman IR, O'Brien PC, Ness A, Caskey PE, Karnes J, Bushek W. Introduction of automated systems to evaluate touch-pressure, vibration, and thermal cutaneous sensation in man. Ann Neurol. 1978 Dec; 4(6):502-10.
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  370. Dyck PJ, Johnson WJ, Lambert EH, O'Brien PC, Daube JR, Oviatt KF. Comparison of symptoms, chemistry, and nerve function to assess hemodialysis adequacy. Proceedings of the Clinical Dialysis & Transplant Forum. 1978 Nov; 8:246-9.
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  371. Smith TF, Weed LA, Pettersen GR, O'Brien PC. A comparison of genital infections caused by chlamydia trachomatis and by neisseria gonorrhoeae. Am J Clin Pathol. 1978 Sep; 70(3):333-6.
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  372. Labarthe DR, Adam E, Noller KL, O'Brien PC, Robboy SJ, Tilley BC, Townsend D, Barnes AB, Kaufman RH, Decker DG, Fish CR, Herbst AL, Gundersen J, Kurland LT. Design and preliminary observations of national cooperative diethylstilbestrol adenosis (desad project). Obstet Gynecol. 1978 Apr; 51:453-458.
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  373. Dyck PJ, O'Brien PC, Oviatt KF, Bastron JA, Daube JR, Dinapoli RP, Groover RV, Stevens JC. Suggestive preliminary evidence from controlled 3-month clinical trials that prednisone improves chronic inflammatory polyradiculoneuropathy. Trans Am Neurol Assoc. 1978; 103:26-8.
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  374. Johnson WJ, O'Brien PC. Effectiveness of intestinal phosphate binders in patients maintained by hemodialysis. Nephron. 1978; 21(3):123-30.
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  375. O'Brien PC. A nonparametric test for association with censored data. Biometrics. 1978; 34:43-51.
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  376. Dyck PJ, Stevens C, Ohta M, Pollock M, Ohnishi A, Jedrzejowska H, Kawamura Y, O'Brien P, Offord K, Low PA. Towards a three-dimensional pathologic and morphometric evaluation of the peripheral nervous system in peripheral neuropathy. Rinsho Shinkeigaku. 1977 Dec; 17(12):800-4.
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  377. Karnes J, Robb R, O'Brien PC, Lambert EH, Dyck PJ. Computerized image recognition for morphometry of nerve attribute of shape of sampled transverse sections of myelinated fibers which best estimates their average diameter. J Neurol Sci. 1977 Oct; 34(1):43-51.
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  378. Reese DF, O'Brien PC, Beeler GW Jr, Gerding PR, Romme CR. A statistical description of the normal computerized brain scan. AJR Am J Roentgenol. 1977 Sep; 129(3):457-62.
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  379. Kawamura Y, O'Brien P, Okazaki H, Dyck PJ. Lumbar motoneurons of man II: the number and diameter distribution of large- and intermediate-diameter cytons in "motoneuron columns" of spinal cord of man. Journal of Neuropathology & Experimental Neurology. 1977 Sep-Oct; 36(5):861-70.
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  380. Carpenter JR, Bunch TW, Engel AG, O'Brien PC. Survival in polymyositis: corticosteroids and risk factors. J Rheumatol. 1977 Summer; 4(2):207-14.
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  381. Dyck PJ, O'Brien PC, Ohnishi A. Lead neuropathy: 2. Random distribution of segmental demyelination among "old internodes" of myelinated fibers. Journal of Neuropathology & Experimental Neurology. 1977 May; 36(3):570-5.
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  382. Kawamura Y, Okazaki H, O'Brien PC, Dyck PJ. Lumbar motoneurons of man: I Number and diameter histogram of alpha and gamma axons of ventral root. J Neuropathol Exp Neurol. 1977; 36:853-860.
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  383. Buntain WL, Pregler M, O'Brien PC, Lynn HB. Axillary vs. rectal temperature: A comparative study. J Louisiana St Med Soc. 1977; 129:5-8.
  384. Buckingham JM, Howard FM Jr, Bernatz PE, Payne WS, Harrison EG Jr, O'Brien PC, Weiland LH. The value of thymectomy in myasthenia gravis: a computer-assisted matched study. Ann Surg. 1976 Oct; 184(4):453-8.
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  385. Dyck PJ, O'Brien PC, Bushek W, Oviatt KF, Schilling K, Stevens JC. Clinical vs quantitative evaluation of cutaneous sensation. Arch Neurol. 1976 Sep; 33(9):651-5.
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  386. O'Brien PC. A test for randomness. Biometrics. 1976 Jun; 32:391-401.
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  387. Dyck PJ, Lambert EH, O'Brien PC. Pain in peripheral neuropathy related to rate and kind of fiber degeneration. Neurology. 1976 May; 26(5):466-71.
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  388. Ohnishi A, O'Brien PC, Dyck PJ. Studies to improve fixation of human nerves. V. Effect of temperature, fixative and CaCl2 on density of microtubules and neurofilaments. Journal of Neuropathology & Experimental Neurology. 1976 Mar; 35(2):167-79.
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  389. Ohnishi A, O'Brien PC, Dyck PJ. Studies to improve fixation of human nerves. III. effect of osmolality of glutaraldehyde solutions on relationship of axonal area to number of myelin lamellar. J Neurol Sci. 1976 Feb; 27:193-197.
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  390. Ohnishi A, O'Brien PC, Okazaki H, Dyck PJ. Morphometry of myelinated fibers of fascicles gracilis of man. J Neurol Sci. 1976 Feb; 27:163-172.
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  391. Lofgren EP, Coates HL, O'Brien PC. Clinically suspect pulmonary embolism after vein stripping. Mayo Clin Proc. 1976 Feb; 51(2):77-80.
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  392. Ohnishi A, O'Brien PC, Dyck PJ. Studies to improve fixation of human nerves. IV. Effect of time elapsed between death and glutaraldehyde fixation on disity of microtubules and neurofilaments. J Neuropathol Exp Neurol. 1976 Jan; 35:26-29.
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  393. Divertie MB, Cassan SM, O'Brien PC, Brown AL Jr. Fine structural morphometry of diffuse lung diseases with abnormal blood-air gas transfer. Mayo Clin Proc. 1976 Jan; 51(1):42-7.
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  394. Wyllie JW 3rd, Kern EB, O'Brien PC, Hyatt RE. Alteration of pulmonary function associated with artificial nasal obstruction. Surg Forum. 1976; 27(62):535-7.
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  395. Dyck PJ, Johnson WJ, Nelson RA, Lambert EH, O'Brien PC. Uremic neuropathy. III. Controlled study of restricted protein and fluid diet and infrequent hemodialysis versus conventional hemodialysis treatment. Mayo Clin Proc. 1975 Nov; 50(11):641-9.
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  396. Kueppers F, O'Brien PC, Passarge E, Rudiger HW. Alpha1-antitrypsin phenotypes in sex chromosome mosaicism. J Med Genet. 1975 Sep; 12:263-264.
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  397. Reese DF, O'Brien PC, Beeler GW Jr, Gerding PR, McCullough EC. An investigation for extracting more information from computerized tomography scans. American Journal of Roentgenology, Radium Therapy & Nuclear Medicine. 1975 Jun; 124(2):177-85.
  398. Guller B, O'Brien PC, Smith RE, Weidman WH, Dushane JW. Computer interpretation of frank vectorcardiograms in normal infant: longitudinal and cross-sectional observations from birth to two years of age. J Electrocardiol. 1975 Mar; 8:201-208.
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  399. Bunch TW, Hunder GG, McDuffie FC, O'Brien PC, Markowitz H. Synovial fluid complement determination as a diagnostic aid in inflammatory joint disease. Mayo Clin Proc. 1974 Oct; 49(10):715-20.
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  400. Guller B, O'Brien PC, Smith RE, Weidman WH. Computer interpretation of right ventricular hypertrophy from frank vectorcardiogram in children with congenital heart disease. Mayo Clin Proc. 1974 Jul; 49(7):466-73.
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  401. Ohnishi A, O'Brien PC, Dyck PJ. Studies to improve fixation of human nerves. part 2. effect of time elapsed between death and glutaraldehyde fixation on relationship of axonal area to number of myelin lamellae. J Neurol Sci. 1974 Mar; 23:387-390.
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  402. Ramos R, Spencer RJ, O'Brien PC, Hill JR. Effects of patient age and previous operations on completeness of sigmoidoscopy. Diseases of the Colon & Rectum. 1974 Jan-Feb; 17(1):61-3.
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  403. O'Brien PC. A procedure for the sequential interval estimation of the shape parameter of the gamma distribution. Technometrics. 1973 Aug; 15:563-570.
  404. Mayne JG, Martin MJ, Taylor WF, O'Brien PC, Fleming PJ. A health questionnaire based on paper-and-pencil medium, individualized and produced by computer: usefulness and acceptability to physicians. Ann Intern Med. 1972 Jun; 76:923-930.
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  405. Dyck PJ, Schultz PW, O'Brien PC. Quantitation of touch-pressure sensation. Arch Neurol. 1972 May; 26(5):465-73.
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  406. Guller B, Berg KL, Weidman WH, O'Brien PP, Dushane JW, Smith RE. Computer interpretation of Frank vectorcardiogram in normal newborns: identification of right ventricular dominance patterns. J Electrocardiol. 1972; 5(4):307-16.
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  407. Dyck PJ, Johnson WJ, Lambert EH, O'Brien PC. Segmental demyelination secondary to axonal degeneration in uremic neuropathy. Mayo Clin Proc. 1971 Jun; 46(6):400-31.
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  408. Dyck PJ, Lambert EH, Sanders K, O'Brien PC. Severe hypomyelination and marked abnormality of conduction in Dejerine-Sottas hypertrophic neuropathy: myelin thickness and compound action potential of sural nerve in vitro. Mayo Clin Proc. 1971 Jun; 46(6):432-6.
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