Publications

  1. Springer W, Kahle PJ. Regulation of PINK1-Parkin-mediated mitophagy. Autophagy. 2011 Mar; 7(3):266-78. 2201643
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  2. Geisler S, Holmstrom KM, Treis A, Skujat D, Weber SS, Fiesel FC, Kahle PJ, Springer W. The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations. Autophagy. 2010 Oct; 6(7):871-8. Epub 2010 Oct 03. 2201644
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  3. Cornejo Castro EM, Waak J, Weber SS, Fiesel FC, Oberhettinger P, Schutz M, Autenrieth IB, Springer W, Kahle PJ. Parkinson's disease-associated DJ-1 modulates innate immunity signaling in Caenorhabditis elegans. J Neural Transm. 2010 May; 117(5):599-604. Epub 2010 Apr 08. 2201645
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  4. Geisler S, Holmstrom KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol. 2010 Feb; 12(2):119-31. Epub 2010 Jan 24. 2201664
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  5. Fiesel FC, Voigt A, Weber SS, Van den Haute C, Waldenmaier A, Gorner K, Walter M, Anderson ML, Kern JV, Rasse TM, Schmidt T, Springer W, Kirchner R, Bonin M, Neumann M, Baekelandt V, Alunni-Fabbroni M, Schulz JB, Kahle PJ. Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. EMBO J. 2010 Jan 6; 29(1):209-21. Epub 2009 Nov 12. 2201647
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  6. Klein CL, Rovelli G, Springer W, Schall C, Gasser T, Kahle PJ. Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment. J Neurochem. 2009 Nov; 111(3):703-15. Epub 2009 Aug 27. 2201648
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  7. Hasegawa T, Treis A, Patenge N, Fiesel FC, Springer W, Kahle PJ. Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways. J Neurochem. 2008 Jun; 105(5):1700-15. Epub 2008 Feb 04. 2201649
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  8. Springer W, Kahle PJ. Mechanisms and models of alpha-synuclein-related neurodegeneration. Curr Neurol Neurosci Rep. 2006 Sep; 6(5):432-6. 2201651
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  9. Springer W, Hoppe T, Schmidt E, Baumeister R. A Caenorhabditis elegans Parkin mutant with altered solubility couples alpha-synuclein aggregation to proteotoxic stress. Hum Mol Genet. 2005 Nov 15; 14(22):3407-23. Epub 2005 Oct 04. 2201652
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  10. Hoppe T, Cassata G, Barral JM, Springer W, Hutagalung AH, Epstein HF, Baumeister R. Regulation of the myosin-directed chaperone UNC-45 by a novel E3/E4-multiubiquitylation complex in C. elegans. Cell. 2004 Aug 6; 118(3):337-49. 2201653
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