Publications

Than M, Herbert M, Flaws D, Cullen L, Hess E, Hollander JE, Diercks D, Ardagh MW, Kline JA, Munro Z, Jaffe A. What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the Emergency Department?: A clinical survey. Int J Cardiol. 2013 Jul 1; 166(3):752-4. Epub 2012 Oct 22. 2279355
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Killu AM, Liang JJ, Jaffe AS. Erdheim-Chester disease with cardiac involvement successfully treated with anakinra. Int J Cardiol. 2013 May 06. [Epub ahead of print] 2322690
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Dunlay SM, Jaffe AS. Are biomarkers the answer to the heart failure readmissions problem? Clin Chem. 2013 May; 59(5):737-9. Epub 2013 Mar 07. 2324432
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Miller WL, Grill DE, Struck J, Jaffe AS. Association of hyponatremia and elevated copeptin with death and need for transplantation in ambulatory patients with chronic heart failure. Am J Cardiol. 2013 Mar 15; 111(6):880-5. Epub 2012 Dec 28. 2292667
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Keddis MT, El-Zoghby ZM, El Ters M, Rodrigo E, Pellikka PA, Jaffe AS, Cosio FG. Cardiac troponin T before and after kidney transplantation: determinants and implications for posttransplant survival. Am J Transplant. 2013 Feb; 13(2):406-14. Epub 2012 Nov 08. 2272465
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Nordenskjold AM, Ahlstrom H, Eggers KM, Frobert O, Jaffe AS, Venge P, Lindahl B. Short- and long-term individual variation in cardiac troponin in patients with stable coronary artery disease. Clin Chem. 2013 Feb; 59(2):401-9. Epub 2012 Nov 09. 2303964
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Jaffe AS. Third universal definition of myocardial infarction. Clin Biochem. 2013 Jan; 46(1-2):1-4. Epub 2012 Nov 02. 2281841
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Korley FK, Jaffe AS. Preparing the United States for high-sensitivity cardiac troponin assays. J Am Coll Cardiol. 2013; 61(17):1753-8. 2324360
Olaf S, Debora B, Ricarda B, Gunnar B, Jochen K, Schimke I, Halle M, Jaffe A. Exercise tolerance in asymptomatic patients with moderate-severe valvular heart disease and preserved ejection fraction. Arch Med Sci. 2012 Dec 20; 8(6):1018-26. Epub 2012 Dec 19. 2300634
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Sheldon SH, Crandall MA, Jaffe AS. Myocarditis with ST elevation and elevated cardiac enzymes misdiagnosed as an ST-elevation myocardial infarction. J Emerg Med. 2012 Dec; 43(6):996-9. Epub 2010 Dec 16. 2136128
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Kaleta EJ, Jaffe AS, Baumann NA, Block DR. A case of floating gel. Clin Chem. 2012 Nov; 58(11):1604-5. 2280219
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Sheldon SH, Saenger AK, Jaffe AS. Incidence and significance of elevated lactate in the identification of critically ill patients. Clin Chem Lab Med. 2012 Oct 1; 50(10):1819-23. 2284171
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Whang W, Burg MM, Carney RM, Freedland KE, Bigger JT, Catellier D, Czajkowski S, Frasure-Smith N, Haas DC, Jaffe AS, Lesperance F, Medina V, Duer-Hefele J, Osorio GA, Parsons F, Shapiro PA, Sheps DS, Vaccarino V, Davidson KW. Design and baseline data from the vanguard of the Comparison of Depression Interventions after Acute Coronary Syndrome (CODIACS) randomized controlled trial. Contemp Clin Trials. 2012 Sep; 33(5):1003-10. Epub 2012 May 25. 2275238
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Thygesen K, Mair J, Mueller C, Huber K, Weber M, Plebani M, Hasin Y, Biasucci LM, Giannitsis E, Lindahl B, Koenig W, Tubaro M, Collinson P, Katus H, Galvani M, Venge P, Alpert JS, Hamm C, Jaffe AS, Study Group on Biomarkers in Cardiology of the ESC Recommendations for the use of natriuretic peptides in acute cardiac care: a position statement from the Study Group on Biomarkers in Cardiology of the ESC Working Group on Acute Cardiac Care. Eur Heart J. 2012 Aug; 33(16):2001-6. Epub 2011 Feb 02. 2276798
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Dunlay SM, Weston SA, Killian JM, Bell MR, Jaffe AS, Roger VL. Thirty-day rehospitalizations after acute myocardial infarction: a cohort study. Ann Intern Med. 2012 Jul 3; 157(1):11-8. 2261921
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Ayub B, Martinez MW, Jaffe AS, Couri DM. Giant saphenous vein graft pseudoaneurysm: treatment with a vascular occlusion device. Interact Cardiovasc Thorac Surg. 2012 Jul; 15(1):164-5. Epub 2012 Mar 28. 2253590
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Koch CD, Wockenfus AM, Saenger AK, Jaffe AS, Karon BS. BD rapid serum tubes reduce false positive plasma troponin T results on the Roche Cobas e411 analyzer. Clin Biochem. 2012 Jul; 45(10-11):842-4. Epub 2012 Apr 26. 2253593
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Jaffe AS. Troponin--past, present, and future. Curr Probl Cardiol. 2012 Jun; 37(6):209-28. 2253332
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Deo S, Greason KL, Gulati R, Jaffe AS, Holmes DR. Balloon aortic valvuloplasty under temporary mechanical circulatory support as a bridge to aortic valve replacement in a patient with hemodynamic failure secondary to critical aortic valve stenosis. Heart Surg Forum. 2012 Jun; 15(3):E177-9. 2252471
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Miller WL, Grill DE, Jaffe AS. Comparison of novel pro-BNP(1-108) and standard BNP assays in heart failure patients. Clin Chim Acta. 2012 May 18; 413(9-10):920-6. Epub 2012 Feb 16. 2227678
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Jaffe AS, Apple FS, Lindahl B, Mueller C, Katus HA. Why all the struggle about CK-MB and PCI? Eur Heart J. 2012 May; 33(9):1046-8. Epub 2012 Jan 11. 2216548
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Landesberg G, Gilon D, Meroz Y, Georgieva M, Levin PD, Goodman S, Avidan A, Beeri R, Weissman C, Jaffe AS, Sprung CL. Diastolic dysfunction and mortality in severe sepsis and septic shock. Eur Heart J. 2012 Apr; 33(7):895-903. Epub 2011 Sep 11. 2242408
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Alpert JS, Jaffe AS. Interpreting biomarkers during percutaneous coronary intervention: the need to reevaluate our approach. Arch Intern Med. 2012 Mar 26; 172(6):508-9. Epub 2012 Feb 27. 2227663
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Gerber Y, Jaffe AS, Weston SA, Jiang R, Roger VL. Prognostic value of cardiac troponin T after myocardial infarction: a contemporary community experience. Mayo Clin Proc. 2012 Mar; 87(3):247-54. 2229016
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Twerenbold R, Jaffe A, Reichlin T, Reiter M, Mueller C. High-sensitive troponin T measurements: what do we gain and what are the challenges? Eur Heart J. 2012 Mar; 33(5):579-86. Epub 2012 Jan 19. 2235866
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Miller WL, Hartman KA, Grill DE, Struck J, Bergmann A, Jaffe AS. Serial measurements of midregion proANP and copeptin in ambulatory patients with heart failure: incremental prognostic value of novel biomarkers in heart failure. Heart. 2012 Mar; 98(5):389-94. Epub 2011 Dec 22. 2213889
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Hess EP, Brison RJ, Perry JJ, Calder LA, Thiruganasambandamoorthy V, Agarwal D, Sadosty AT, Silvilotti ML, Jaffe AS, Montori VM, Wells GA, Stiell IG. Development of a clinical prediction rule for 30-day cardiac events in emergency department patients with chest pain and possible acute coronary syndrome. Ann Emerg Med. 2012 Feb; 59(2):115-25.e1. Epub 2011 Sep 01. 2187678
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Jaffe AS, Wu AH. Troponin release--reversible or irreversible injury? Should we care? Clin Chem. 2012 Jan; 58(1):148-50. Epub 2011 Oct 28. 2203484
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Schmickl CN, Shahjehan K, Li G, Dhokarh R, Kashyap R, Janish C, Alsara A, Jaffe AS, Hubmayr RD, Gajic O. Decision support tool for early differential diagnosis of acute lung injury and cardiogenic pulmonary edema in medical critically ill patients. Chest. 2012 Jan; 141(1):43-50. Epub 2011 Oct 26. 2201896
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Katus HA, Giannitsis E, Jaffe AS. Interpreting changes in troponin--clinical judgment is essential. Clin Chem. 2012 Jan; 58(1):39-43. 2225285
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Pervaiz MA, Gau G, Jaffe AS, Saenger AK, Baudhuin L, Ellison J. A Non-classical Presentation of Tangier Disease with Three ABCA1 Mutations. JIMD Rep. 2012; 4:109-11. Epub 2011 Sep 28. 2305466
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Eggers KM, Jaffe AS, Svennblad B, Lindahl B. A novel approach to cardiac troponins to improve the diagnostic work-up in chest pain patients. Critical Pathways in Cardiology. 2012; 11(4):199-205. 2293285
Jaffe AS, Apple FS. The third universal definition of myocardial infarction - Moving forward. Clin Chem. 2012; 58(12):1727-8. 2290298
Koerbin G, Potter JM, Abhayaratna WP, Telford RD, Badrick T, Apple FS, Jaffe AS, Hickman PE. Longitudinal studies of cardiac troponin I in a large cohort of healthy children. Clin Chem. 2012; 58(12):1665-72. 2290305
Thygesen K Mair J Giannitsis E Mueller C Lindahl B Blankenberg S Huber K Plebani M Biasucci LM Tubaro M Collinson P Venge P Hasin Y Galvani M Koenig W Hamm C Alpert JS Katus H Jaffe AS, The Study Group on Biomarkers in Cardiology of the ESC Working Group How to use high-sensitivity cardiac troponins in acute cardiac care. EHJ. 2012 Epub 2012 Jun 21. 2253592
Jaffe AS, Vasile VC, Milone M, Saenger AK, Olson KN, Apple FS. Diseased skeletal muscle: a noncardiac source of increased circulating concentrations of cardiac troponin T. J Am Coll Cardiol. 2011 Oct 18; 58(17):1819-24. Epub 2011 Sep 29. 2197022
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Oliver LK, Voskoboev N, Heser D, McConnell JP, Hodel-Hanson S, Callanan H, Jaffe AS. Assessment of clinical performance without adequate analytical validation: A prescription for confusion. Clin Biochem. 2011 Oct; 44(14-15):1247-52. Epub 2011 Jul 20. 2179349
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Body R, Carley S, McDowell G, Jaffe AS, France M, Cruickshank K, Wibberley C, Nuttall M, Mackway-Jones K. Rapid exclusion of acute myocardial infarction in patients with undetectable troponin using a high-sensitivity assay. J Am Coll Cardiol. 2011 Sep 20; 58(13):1332-9. 2199807
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Jaffe AS. The 10 commandments of troponin, with special reference to high sensitivity assays. Heart. 2011 Jun; 97(11):940-6. 2163892
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Schulz O, Reinicke M, Kramer J, Berghofer G, Bensch R, Schimke I, Jaffe A. Pregnancy-associated plasma protein A values in patients with stable cardiovascular disease: use of a new monoclonal antibody-based assay. Clin Chim Acta. 2011 May 12; 412(11-12):880-6. Epub 2011 Jan 14. 2166968
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Miller WL, Phelps MA, Wood CM, Schellenberger U, Van Le A, Perichon R, Jaffe AS. Comparison of mass spectrometry and clinical assay measurements of circulating fragments of B-type natriuretic peptide in patients with chronic heart failure. Circ Heart Fail. 2011 May; 4(3):355-60. Epub 2011 Feb 03. 2147410
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Arruda-Olson AM, Roger VL, Jaffe AS, Hodge DO, Gibbons RJ, Miller TD. Troponin T levels and infarct size by SPECT myocardial perfusion imaging. JACC Cardiovasc Imaging. 2011 May; 4(5):523-33. 2165339
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Saenger AK, Beyrau R, Braun S, Cooray R, Dolci A, Freidank H, Giannitsis E, Gustafson S, Handy B, Katus H, Melanson SE, Panteghini M, Venge P, Zorn M, Jarolim P, Bruton D, Jarausch J, Jaffe AS. Multicenter analytical evaluation of a high-sensitivity troponin T assay. Clin Chim Acta. 2011 Apr 11; 412(9-10):748-54. Epub 2011 Jan 08. 2141642
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Martinez MW, Rasmussen KG, Mueller PS, Jaffe AS. Troponin elevations after electroconvulsive therapy: the need for caution. Am J Med. 2011 Mar; 124(3):229-34. 2152027
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Hallen J, Jensen JK, Buser P, Jaffe AS, Atar D. Relation of cardiac troponin I and microvascular obstruction following ST-elevation myocardial infarction. Acute Card Care. 2011 Mar; 13(1):48-51. Epub 2011 Jan 18. 2155329
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Eggers KM, Jaffe AS, Venge P, Lindahl B. Clinical implications of the change of cardiac troponin I levels in patients with acute chest pain - an evaluation with respect to the Universal Definition of Myocardial Infarction. Clin Chim Acta. 2011 Jan 14; 412(1-2):91-7. Epub 2010 Sep 22. 2141967
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Thygesen K, Mair J, Katus H, Plebani M, Venge P, Collinson P, Lindahl B, Giannitsis E, Hasin Y, Galvani M, Tubaro M, Alpert JS, Biasucci LM, Koenig W, Mueller C, Huber K, Hamm C, Jaffe AS. Recommendations for the use of natriuretic peptides in acute cardiac care: A position statement from the Study Group on Biomarkers in Cardiology of the ESC Working Group on Acute Cardiac Care. EHJ (in press). 2011; EHJ 2011. 2220421
Landesberg G, Gilon D, Meroz Y, Georgieva M, Levin PD, Goodman S, Avidan A, Beeri R, Wesissman C, Jaffe AS, Sprung CL. Diastolic dysfunction and mortality in severe sepsis and septic shock. EHJ. 2011; in press Epub 0. 2220430
Hallen J, Jensen JK, Fagerland MW, Jaffe AS, Atar D. Cardiac troponin I for the prediction of functional recovery and left ventricular remodelling following primary percutaneous coronary intervention for ST-elevation myocardial infarction. Heart. 2010 Dec; 96(23):1892-7. 2130221
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Vasile VC, Chai HS, Khambatta S, Afessa B, Jaffe AS. Significance of elevated cardiac troponin T levels in critically ill patients with acute respiratory disease. Am J Med. 2010 Nov; 123(11):1049-58. 2124151
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Hallen J, Johansen OE, Birkeland KI, Gullestad L, Aakhus S, Endresen K, Tjora S, Jaffe AS, Atar D. Determinants and prognostic implications of Cardiac Troponin T measured by a sensitive assay in Type 2 Diabetes Mellitus. Cardiovascular Diabetology. 2010 Sep 15; 9. 2119018
Thygesen K, Johannes M, Katus H, Plebani M, Verge P, Collinson P, Lindahl B, Giannitsis E, Hasin Y, Galvani M, Tubaro M, Alpert JS, Biasucci LM, Koenig W, Mueller CH, Huber K, Hamm C, Jaffe AS. The Study Group on Biomarkers in Cardiology of the ESC Working Group on Acute Cardiac Care Recommendations for the use of cardiac troponin measurement in acute cardiac care. EHJ. 2010 Sept; 31(18):2197-2204. 2220417
Baudhuin LM, Miller WL, Train L, Bryant S, Hartman KA, Phelps M, Larock M, Jaffe AS. Relation of ADRB1, CYP2D6, and UGT1A1 polymorphisms with dose of, and response to, carvedilol or metoprolol therapy in patients with chronic heart failure. Am J Cardiol. 2010 Aug 1; 106(3):402-8. 2106678
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Jaffe AS, Apple FS. In reply. Clin Chem. 2010 Jul; 56(7):1199-200. Epub 2010 May 20. 2002101
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Vasile VC, Saenger AK, Kroning JM, Jaffe AS. Biological and analytical variability of a novel high-sensitivity cardiac troponin T assay. Clin Chem. 2010 Jul; 56(7):1086-90. Epub 2010 May 14. 2002154
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Schulz O, Reinicke M, Berghoefer GH, Bensch R, Kraemer J, Schimke I, Jaffe AS. High-sensitive cardiac troponin I (hs-cTnI) values in patients with stable cardiovascular disease: an initial foray. Clin Chim Acta. 2010 Jun 3; 411(11-12):812-7. Epub 2010 Feb 24. 2102285
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Jaffe AS, Apple FS, Morrow DA, Lindahl B, Katus HA. Being rational about (im)precision: a statement from the Biochemistry Subcommittee of the Joint European Society of Cardiology/American College of Cardiology Foundation/American Heart Association/World Heart Federation Task Force for the definition of myocardial infarction. Clin Chem. 2010 Jun; 56(6):941-3. Epub 2010 Apr 01. 1995655
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Arruda-Olson AM, Enriquez-Sarano M, Bursi F, Weston SA, Jaffe AS, Killian JM, Roger VL. Left ventricular function and C-reactive protein levels in acute myocardial infarction. Am J Cardiol. 2010 Apr 1; 105(7):917-21. 1992798
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Kavsak PA, Worster A, You JJ, Oremus M, Elsharif A, Hill SA, Devereaux PJ, MacRae AR, Jaffe AS. Identification of myocardial injury in the emergency setting. Clin Biochem. 2010 Apr; 43(6):539-44. Epub 2009 Dec 21. 1998041
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Hess EP, Perry JJ, Calder LA, Thiruganasambandamoorthy V, Body R, Jaffe A, Wells GA, Stiell IG. Prospective validation of a modified thrombolysis in myocardial infarction risk score in emergency department patients with chest pain and possible acute coronary syndrome. Acad Emerg Med. 2010 Apr; 17(4):368-75. 1995622
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Kavsak PA, Newman AM, Ko DT, Macrae AR, Jaffe AS. The use of a cytokine panel to define the long-term risk stratification of heart failure/death in patients presenting with chest pain to the emergency department. Clin Biochem. 2010 Mar; 43(4-5):505-7. Epub 2009 Nov 10. 1990620
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Jaffe AS, Apple FS. High-sensitivity cardiac troponin: hype, help, and reality. Clin Chem. 2010 Mar; 56(3):342-4. Epub 2009 Dec 29. 1978242
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Roger VL, Weston SA, Gerber Y, Killian JM, Dunlay SM, Jaffe AS, Bell MR, Kors J, Yawn BP, Jacobsen SJ. Trends in incidence, severity, and outcome of hospitalized myocardial infarction. Circulation. 2010 Feb 23; 121(7):863-9. Epub 2010 Feb 08. 1987842
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Cullen L, Than M, Brown AF, Richards M, Parsonage W, Flaws D, Hollander JE, Christenson RH, Kline JA, Goodacre S, Jaffe AS. Comprehensive standardized data definitions for acute coronary syndrome research in emergency departments in Australasia. Emerg Med Australas. 2010 Feb; 22(1):35-55. Epub 2010 Feb 04. 1988281
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Giannitsis E, Kurz K, Hallermayer K, Jarausch J, Jaffe AS, Katus HA. Analytical validation of a high-sensitivity cardiac troponin T assay. Clin Chem. 2010 Feb; 56(2):254-61. Epub 2009 Dec 03. 1988047
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Schulz O, Reinicke M, Berghoefer GH, Bensch R, Kraemer J, Schimke I, Jaffe AS. Erratum to High-sensitive cardiac troponin I (hs-cTnl) values in patients with stable cardiovascular disease: An initial foray [Clinica Chimica Acta., 411, (2010), 812-817]. Clin Chim Acta. 2010; 411(17-18):1395-6. 2106866
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Hallen J, Buser P, Schwitter J, Petzelbauer P, Geudelin B, Fagerland MW, Jaffe AS, Atar D. Relation of cardiac troponin I measurements at 24 and 48 hours to magnetic resonance-determined infarct size in patients with ST-elevation myocardial infarction. Am J Cardiol. 2009 Dec 1; 104(11):1472-7. Epub 2009 Oct 14. 1982677
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Miller WL, Hartman KA, Hodge DO, Hartman S, Struck J, Morgenthaler NG, Bergmann A, Jaffe AS. Response of novel biomarkers to BNP infusion in patients with decompensated heart failure: a multimarker paradigm. J Cardiovasc Transl Res. 2009 Dec; 2(4):526-35. Epub 2009 Aug 14. 2103488
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Frye RL, Simari RD, Gersh BJ, Burnett JC, Brumm S, Myerle K, Jaffe AS, Holmes DR, Lerman A, Terzic A. Ethical issues in cardiovascular research involving humans. Circulation. 2009 Nov 24; 120(21):2113-21. 1974103
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Miller WL, Hartman KA, Burritt MF, Grill DE, Jaffe AS. Profiles of serial changes in cardiac troponin T concentrations and outcome in ambulatory patients with chronic heart failure. J Am Coll Cardiol. 2009 Oct 27; 54(18):1715-21. 1969650
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Kavsak PA, Wang X, Ko DT, MacRae AR, Jaffe AS. Short- and long-term risk stratification using a next-generation, high-sensitivity research cardiac troponin I (hs-cTnI) assay in an emergency department chest pain population. Clin Chem. 2009 Oct; 55(10):1809-15. Epub 2009 Aug 13. 1970012
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Saenger AK, Dalenberg DA, Bryant SC, Grebe SK, Jaffe AS. Pediatric brain natriuretic peptide concentrations vary with age and sex and appear to be modulated by testosterone. Clin Chem. 2009 Oct; 55(10):1869-75. Epub 2009 Aug 13. 1959346
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Saenger AK, Lockwood C, Snozek CL, Milz TC, Karon BS, Scott MG, Jaffe AS. Catecholamine interference in enzymatic creatinine assays. Clin Chem. 2009 Sep; 55(9):1732-6. Epub 2009 Jul 09. 1952578
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Neizel M, Futterer S, Steen H, Giannitsis E, Reinhardt L, Lossnitzer D, Lehrke S, Jaffe AS, Katus HA. Predicting microvascular obstruction with cardiac troponin T after acute myocardial infarction: a correlative study with contrast-enhanced magnetic resonance imaging. Clin Res Cardiol. 2009 Sep; 98(9):555-62. Epub 2009 Jul 07. 1971865
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Miller WL, Burnett JC Jr, Hartman KA, Hodge DO, Giuliani I, Minard F, Larue C, Jaffe AS. Role for precursor Pro-B type natriuretic peptide in assessing response to therapy and prognosis in patients with decompensated heart failure treated with nesiritide. Clin Chim Acta. 2009 Aug; 406(1-2):119-23. Epub 2009 Jun 11. 1949883
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Bang H, Mazumdar M, Newman G, Bomback AS, Ballantyne CM, Jaffe AS, August PA, Kshirsagar AV. Screening for kidney disease in vascular patients: SCreening for Occult REnal Disease (SCORED) experience. Nephrol Dial Transplant. 2009 Aug; 24(8):2452-7. Epub 2009 Mar 26. 1965732
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Berridge BR, Pettit S, Walker DB, Jaffe AS, Schultze AE, Herman E, Reagan WJ, Lipshultz SE, Apple FS, York MJ. A translational approach to detecting drug-induced cardiac injury with cardiac troponins: consensus and recommendations from the Cardiac Troponins Biomarker Working Group of the Health and Environmental Sciences Institute. Am Heart J. 2009 Jul; 158(1):21-9. 1965485
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Kavsak PA, Wang X, Henderson M, Ko DT, MacRae AR, Jaffe AS. PAPP-A as a marker of increased long-term risk in patients with chest pain. Clin Biochem. 2009 Jul; 42(10-11):1012-8. Epub 2009 Mar 25. 1965512
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Landesberg G, Beattie WS, Mosseri M, Jaffe AS, Alpert JS. Perioperative myocardial infarction. Circulation. 2009 Jun 9; 119(22):2936-44. 1951165
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Hickson LT, El-Zoghby ZM, Lorenz EC, Stegall MD, Jaffe AS, Cosio FG. Patient survival after kidney transplantation: relationship to pretransplant cardiac troponin T levels. Am J Transplant. 2009 Jun; 9(6):1354-61. Epub 2009 May 13. 1944212
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Feng D, Syed IS, Martinez M, Oh JK, Jaffe AS, Grogan M, Edwards WD, Gertz MA, Klarich KW. Intracardiac thrombosis and anticoagulation therapy in cardiac amyloidosis. Circulation. 2009 May 12; 119(18):2490-7. Epub 2009 May 04. 1940725
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Vasile VC, Babuin L, Ting HH, Bell MR, Orme NM, Yuan BY, Perez JA, Alegria JR, Bellolio F, Haro LH, Jaffe AS. Aborted myocardial infarction: is it real in the troponin era? Am Heart J. 2009 Apr; 157(4):636-41. Epub 2009 Jan 31. 1933629
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Carney RM, Freedland KE, Steinmeyer B, Blumenthal JA, de Jonge P, Davidson KW, Czajkowski SM, Jaffe AS. History of depression and survival after acute myocardial infarction. Psychosom Med. 2009 Apr; 71(3):253-9. Epub 2009 Feb 27. 1928096
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Carney RM, Freedland KE, Steinmeyer B, Blumenthal JA, de Jonge P, Davidson KW, Czajkowski SM, Jaffe AS. History of depression and survival following acute myocardial infarction. Psycho Med. 2009 Apr; 1:253-259. 1918043
Gerber Y, Dunlay SM, Jaffe AS, McConnell JP, Weston SA, Killian JM, Roger VL. Plasma lipoprotein-associated phospholipase A2 levels in heart failure: association with mortality in the community. Atherosclerosis. 2009 Apr; 203(2):593-8. Epub 2008 Aug 07. 1915656
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Kavsak PA, MacRae AR, Yerna MJ, Jaffe AS. Analytic and clinical utility of a next-generation, highly sensitive cardiac troponin I assay for early detection of myocardial injury. Clin Chem. 2009 Mar; 55(3):573-7. Epub 2009 Jan 23. 1935000
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Bursi F, Barbieri A, Politi L, Di Girolamo A, Malagoli A, Grimaldi T, Rumolo A, Busani S, Girardis M, Jaffe AS, Modena MG. Perioperative red blood cell transfusion and outcome in stable patients after elective major vascular surgery. Eur J Vasc Endovasc Surg. 2009 Mar; 37(3):311-8. Epub 2008 Dec 25. 1935001
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McConnell JP, Jaffe AS. The spin stops here: inhibition of lipoprotein-associated phospholipase A2-- a promising target but a negative initial trial? Clin Chem. 2009 Jan; 55(1):21-3. Epub 2008 Dec 01. 1915269
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Miller WL, Hartman KA, Grill DE, Burnett JC Jr, Jaffe AS. Only large reductions in concentrations of natriuretic peptides (BNP and NT-proBNP) are associated with improved outcome in ambulatory patients with chronic heart failure. Clin Chem. 2009 Jan; 55(1):78-84. Epub 2008 Nov 21. 1915316
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Eggers KM, Jaffe AS, Lind L, Venge P, Lindahl B. Value of cardiac troponin I cutoff concentrations below the 99th percentile for clinical decision-making. Clin Chem. 2009 Jan; 55(1):85-92. Epub 2008 Nov 06. 1934936
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Vasile VC, Babuin L, Rio Perez JA, Alegria JR, Song LM, Chai HS, Afessa B, Jaffe AS. Long-term prognostic significance of elevated cardiac troponin levels in critically ill patients with acute gastrointestinal bleeding. Crit Care Med. 2009 Jan; 37(1):140-7. 1891216
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Saab PG, Bang H, Williams RB, Powell LH, Schneiderman N, Thoresen C, Burg M, Keefe F, for the ENRICHD Investigators. The impact of cognitive behavioral group training on event-free survival in patients with myocardial infarction: The ENRICHD experience. J Psycho Res. 2009; 67:45-56. 1957121
Peleg A, Jaffe AS, Hasin Y. Enzyme-linked immunoabsorbent assay for detection of human serine protease corin in blood. Clinica Chimica Acta. 2009; 409(1-2):85-89. 1965010
Lett HS, Blumenthal JA, Babyak MA, Catellier DJ, Carney RM, Berkman LF, Burg MM, Mitchell P, Jaffe AS, Schneiderman N. Dimensions of social support and depression in patients at increased psychosocial risk recovering from myocardial infarction. Int J Behav Med. 2009; 16(3):248-58. 1978812
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Vasile VC, Blauwet LA, Jaffe AS. Serial determination of troponin concentrations in the diagnosis of acute myocardial infarction. Heart and Metabolism. 2009; (43):27-9. 1978807
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Vasile VC, Jaffe AS. The biological basis of troponin in heart disease: Possible uses for troponin fragmentology. Heart Metab. 2009(43):5-8. 1978808
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Saenger AK, Jaffe AS. Requiem for a heavyweight: the demise of creatine kinase-MB. Circulation. 2008 Nov 18; 118(21):2200-6. 1915364
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Hickson LJ, Cosio FG, El-Zoghby ZM, Gloor JM, Kremers WK, Stegall MD, Griffin MD, Jaffe AS. Survival of patients on the kidney transplant wait list: relationship to cardiac troponin T. Am J Transplant. 2008 Nov; 8(11):2352-9. Epub 2008 Sep 10. 1894925
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Alpert JS, Thygesen K, White HD, Jaffe AS. Implications of the universal definition of myocardial infarction. Nat Clin Pract Cardiovasc Med. 2008 Nov; 5(11):678-9. Epub 2008 Sep 09. 1894926
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Arruda-Olson AM, Pellikka PA, Bursi F, Jaffe AS, Santrach PJ, Kors JA, Killian JM, Weston SA, Roger VL. Left ventricular function and heart failure in myocardial infarction: impact of the new definition in the community. Am Heart J. 2008 Nov; 156(5):810-5. Epub 2008 Sep 09. 1911227
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Thygesen K, Alpert JS, Jaffe AS, White HD. Diagnostic application of the universal definition of myocardial infarction in the intensive care unit. Curr Opin Crit Care. 2008 Oct; 14(5):543-8. 1894923
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Alpert JS, Thygesen K, Jaffe A, White HD. The universal definition of myocardial infarction: a consensus document: ischaemic heart disease. Heart. 2008 Oct; 94(10):1335-41. 1955161
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Trockel M, Burg M, Jaffe A, Barbour K, Taylor CB. Smoking behavior postmyocardial infarction among ENRICHD trial participants: Cognitive behavior therapy intervention for depression and low perceived social support compared with care as usual. Psychosom Med. 2008 Oct; 70(8):875-82. 1947763
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Carney RM, Steinmeyer B, Freedland KE, Blumenthal JA, Stein PK, Steinhoff WA, Howells WB, Berkman LF, Watkins LL, Czajkowski SM, Domitrovich PP, Burg MM, Hayano J, Jaffe AS. Nighttime heart rate and survival in depressed patients post acute myocardial infarction. Psychosom Med. 2008 Sep; 70(7):757-63. Epub 2008 Aug 25. 1894927
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Jaffe AS. Key issues in the developing synergism between cardiovascular imaging and biomarkers. Clin Chem. 2008 Sep; 54(9):1432-42. Epub 2008 Aug 01. 1898876
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Berkman LF, Blumenthal J, Burg M, Carney RM, Catellier D, Cowan MJ, Czajkowski SM, DeBusk R, Hosking J, Jaffe A, Kaufmann PG, Mitchell P, Norman J, Powell LH, Raczynski JM, Schneiderman N. Effects of treating depression and low-perceived social support on clinical events after myocardial infarction - The enhancing recovery in coronary heart disease patients (ENRICHD) randomized trial. JAMA: Journal of the American Medical Association. 2003 Jun 18; 289(23):3106-16. 1355840
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Woodruff BK, Britton JW, Tigaran S, Cascino GD, Burritt M, McConnell JP, Ravkilde J, Molgaard H, Andreasen F, Dam M, Jaffe AS. Cardiac troponin levels following monitored epileptic seizures. Neurology. 2003 May 27; 60(10):1690-2. 1355731
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Dispenzieri A, Kyle RA, Gertz MA, Therneau TM, Miller WL, Chandrasekaran K, McConnell JP, Burritt MF, Jaffe AS. Survival in patients with primary systemic amyloidosis and raised serum cardiac troponins. Lancet. 2003 May 24; 361(9371):1787-9. 1346819
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Carney RM, Freedland KE, Stein PK, Watkins LL, Catellier D, Jaffe AS, Yeragani VK. Effects of depression on QT interval variability after myocardial infarction. Psychosom Med. 2003 Mar-Apr; 65(2):177-80. 1325128
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Tigaran S, Molgaard H, McClelland R, Dam M, Jaffe AS. Evidence of cardiac ischemia during seizures in drug refractory epilepsy patients. Neurology. 2003 Feb 11; 60(3):492-5. 1318610
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Gheorghiade M, Gattis WA, Adams KF, Jaffe AS, O'Connor CM. Rationale and design of the Pilot Randomized Study of Nesiritide versus Dobutamine in Heart Failure (PRESERVD-HF). Am Heart J. 2003 Feb; 145(2 Suppl S):S55-7. 1318939
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Freedland KE, Rich MW, Skala JA, Carney RM, Davila-Roman VG, Jaffe AS. Prevalence of depression in hospitalized patients with congestive heart failure. Psychosom Med. 2003 Jan-Feb; 65(1):119-28. 1318201
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Apple FS, Wu AHB, Jaffe AS. European Society of Cardiology and American College of Cardiology guidelines for redefinition of myocardial infarction: How to use existing assays clinically and for clinical trials. Am Heart J. 2002 Dec; 144(6):981-6. 1317883
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Aviles RJ, Wright RS, Aviles JM, McDonald F, Ballman K, Harker-Murray A, Scott C, Lauer MS, Kopecky SL, Jaffe AS. Long-term prognosis of patients with clinical unstable angina pectoris without elevation of creatine kinase but with elevation of cardiac troponin I levels. Am J Cardiol. 2002 Oct 15; 90(8):875-8. 1316659
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Wright RS, Reeder GS, Herzog CA, Albright RC, Williams BA, Dvorak DL, Miller WL, Murphy JG, Kopecky SL, Jaffe AS. Acute myocardial infarction and renal dysfunction: a high-risk combination. Ann Intern Med. 2002 Oct 1; 137(7):563-70. 1316302
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Carney RM, Freedland KE, Miller GE, Jaffe AS. Depression as a risk factor for cardiac mortality and morbidity - A review of potential mechanisms. J Psychosom Res. 2002 Oct; 53(4):897-902. 1316707
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Wright RS, Williams BA, Cramner H, Gallahue F, Willmore T, Lewis L, Ladenson JH, Jaffe AS. Elevations of cardiac troponin I are associated with increased short-term mortality in noncardiac critically ill emergency department patients. Am J Cardiol. 2002 Sep 15; 90(6):634-6. 1316205
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Carlson RJ, Navone A, McConnell JP, Burritt M, Castle MC, Grill D, Jaffe AS. Effect of myocardial ischemia on cardiac troponin I and T. Am J Cardiol. 2002 Jan 15; 89(2):224-6. 1008011
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Cantwell RV, Aviles RJ, Bjornsson J, Wright RS, Freeman WK, Oh JK, Hoyer JD, Markovic S, Jaffe AS. Cardiac amyloidosis presenting with elevations of cardiac troponin I and angina pectoris. Clin Cardiol. 2002 Jan; 25(1):33-7. 1007944
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McConnell JP, Branum EL, Ballman KV, Lagerstedt SA, Katzmann JA, Jaffe AS. Gender differences in C-reactive protein concentrations - Confirmation with two sensitive methods. Clinical Chemistry & Laboratory Medicine. 2002; 40(1):56-9. 1315402
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Jaffe AS, World Health Organization, European Society of Cardiology, American College of Cardiology. New standard for the diagnosis of acute myocardial infarction. Cardiol Rev. 2001 Nov-Dec; 9(6):318-22. 1979779
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Miller WL, Wright RS, McGregor CG, Dispenzieri A, McConnell JP, Burritt MF, Jaffe AS. Troponin levels in patients with amyloid cardiomyopathy undergoing cardiac transplantation. Am J Cardiol. 2001 Oct 1; 88(7):813-5. 1003598
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ENRICHD Investigators. Enhancing Recovery in Coronary Heart Disease (ENRICHD) study intervention: rationale and design. Psychosom Med. 2001 Sep-Oct; 63(5):747-55. 1232917
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Antman EM, Corbalan R, Huber K, Jaffe AS. Issues in early risk stratification for UA/NSTEMI. European Heart Journal Supplement. 2001 Aug; 3(J):J6-J14. 1005983
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Carney RM, Freedland KE, Jaffe AS. Depression as a risk factor for coronary heart disease mortality. Arch Gen Psychiatry. 2001 Mar; 58(3):229-30. 1137605
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Jaffe AS. Diagnosis of Acute Myocardial Infarction: The Use of Troponin Markers. Israeli Heart Journal. 2001. 1137648
Jaffe AS. Elevations in cardiac troponin measurements: false false-positives: the real truth. Cardiovasc Toxicol. 2001; 1(2):87-92. 1639517
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Jacobs I, Callanan V, Nichol G, Valenzuela T, Mason P, Jaffe AS, Landau W, Vetter N. The Chain of Survival. Annals of Emergency Medicine/Journal of the American College of Emergency Physicians S5 2001; 37(4). 1648287
Berkman LF, Blumenthal J, Burg M, Carney RM, Catellier D, Cowan MJ, Czajkowski SM, DeBusk R, Hosking J, Jaffe A, Kaufmann PG, Mitchell P, Norman J, Powell LH, Raczynski JM, Schneiderman N. The ENRICHD Investigators. Enhancing Recovery in Coronary Heart Disease (ENRICHD): Baseline Characteristics. Amer J Card. 2001; 88:316-22. 1648344
Ottani F, Galvani M, Nicolini FA, Ferrini D, Pozzati A, Di Pasquale G, Jaffe AS. Elevated cardiac troponin levels predict the risk of adverse outcome in patients with acute coronary syndromes. Am Heart J. 2000 Dec; 140(6):917-27. 1013451
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Dixit S, Castle M, Velu RP, Swisher L, Hodge C, Jaffe AS. Cardiac involvement in patients with acute neurologic disease: confirmation with cardiac troponin I. Arch Intern Med. 2000 Nov 13; 160(20):3153-8. 139931
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Carney RM, Freedland KE, Stein PK, Skala JA, Hoffman P, Jaffe AS. Change in heart rate and heart rate variability during treatment for depression in patients with coronary heart disease. Psychosom Med. 2000 Sep-Oct; 62(5):639-47. 139113
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Alpert JS, Antman E, Apple F, Armstrong PW, Bassand JP, de Luna G, Breithardt G, Chaitman BR, Clemmensen P, Falk E, Fishbein MC, Galvani M, Garson A, Grines C, Hamm C, Jaffe AS, Katus H, Kjekshus J, Klein W, Klootwijk P, Lenfant C, Levy D, Levy RI, Luepke Myocardial infarction redefined - A consensus document of the Joint European Society of cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction. Journal of the American College of Cardiology. 2000 Sep; 36(3):959-69. 149039
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Hutter AM, Amsterdam EA, Jaffe AS. Task force 2: acute coronary syndromes: Section 2B - chest discomfort evaluation in the hospital. J Am Coll Cardiol. 2000 Mar 15; 35(4):853-862. 130264
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Stein PK, Carney RM, Freedland KE, Skala JA, Jaffe AS, Kleiger RE, Rottman JN. Severe depression is associated with markedly reduced heart rate variability in patients with stable coronary heart disease. Journal of Psychosomatic Research. 2000; 48:493-500. 147828
Berkman LF, Blumenthal J, Burg M, Carney RM, Catellier D, Cowan MJ, Czajkowski SM, DeBusk R, Hosking J, Jaffe A, Kaufmann PG, Mitchell P, Norman J, Powell LH, Raczynski JM, Schneiderman N. Enhancing recovery in coronary heart disease (ENRICHD) patients study: Study design and methods. American Heart Journal. 2000; 139:1-9. 1648342
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Freedland KE, Rich MW, Skala JA, Carney RM, Davila-Roman VG, Jaffe AS. Prevalence of depression in hospitalized patients with congestive heart failure. Psychosom Med. 2000; 66:639-47. 1311671
Carney RM, Freedland KE, Veith RC, Cryer PE, Skala JA, Lynch T, Jaffe AS. Major depression, heart rate, and plasma norepinephrine in patients with coronary heart disease. Biol Psychiatry. 1999 Feb 15; 45(4):458-63. 147826
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Carney RM, Freedland EK, Veith RC, Jaffe AS. Can treating depression reduce mortality after an acute myocardail infarction? Psychosomatic Medicine. 1999; 61:666-75. 147827
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Ottani F, Galvani M, Ferrini D, Ladenson JH, Puggioni R, Destro A, Baccos D, Bosi S, Ronchi A, Rusticali, Jaffe AS. Direct comparison of early elevations of cardiac troponin T and I in patients with unstable angina. AHJ. 1999; 137:284-91. 147825
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Jaffe AS. The use of troponin measurements in patients with unstable angina. International Journal of Cardiology 68 Suppl. 1999; 1:S49-53. 1232958
Jaffe AS. 2001--a biomarker odyssey. Clin Chim Acta. 1999 Jun 30;284(2):197-211. 1137645
Carney RM, Freedland KE, Eisen SA, Rich MW, Skala JA, Jaffe AS. Adherence to a prophyllactic medication regimen in patients with symptomatic vs asymptomatic ischemic heart disease Behavioral Medicine. 1998; 24:35-9. 147816
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Jaffe AS, Landau WM, Wetzel RD. Resuscitation 2000: the need for improved databases in regard to neurological outcomes. Resuscitation. 1998; 37:65-6. 1232957
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Landt M, Lawson GM, Helgeson JM, Davila-Roman VG, Ladenson JH, Jaffe AS, Hickner RC. Prolonged exercise decreases serum leptin concentrations. Metabolism: Clinical & Experimental. 1997 Oct; 46(10):1109-12. 100188
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Davila-Roman V, Guest TH, Tuteur PG, Rowe WJ, Ladenson JH, Jaffe AS. Transient right but not left ventricular dysfunction after strenuous exercise at high altitude JACC. 1997; 30:468-73. 147820
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Smith SC, Ladenson JH, Mason JW, Jaffe AS. Elevations of cardiac troponin I associated with myocarditis: Experimental and clinical correlates Circulation. 1997; 95:163-8. 147821
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Hirsch R, Landt Y, Porter S, Canter CE, Jaffe AS, Ladenson JH, Grant JW, Landt M. Cardiac troponin I in Pediatrics: Normal values and potential use in the assessment of cardiac injury J Peds. 1997; 130:827-72. 147822
Galvani M, Ottani F, Ferrini D, Ladenson JH, Destro A, Baccos D, Rusticali F, Jaffe AS. Prognostic influence of elevated values of cardiac troponin I in patients with unstable angina. Circulation. 1997; 95:2053-9. 147823
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Allan JJ, Feld RD, Russell AA, Ladenson JH, Rogers MAM, Kerber RI, Jaffe AS. Cardiac troponin I levels are normal or minimally elevated after transthoracic cardioversion JACC. 1997; 30:1052-6. 147824
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Selis SP, Hom M, Sequeira JM, Tritel M, Gindea A, Ladenson JH, Jaffe AS, Esposito R. Time course of lysophosphatydylcholine relase from ischemic human myocardium parallels the time course of early ischemic ventricular arrhythmia Coron Art Disease. 1997; 8:19-27. 147817
Jaffe AS. More rapid diagnosis of myocardial infarction: Is it worthwhile? American Family Physician. 1997; 55:2591-2594. 1676898
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Adams JE, Davila-Roman VG, Bessey PQ, Blake DP, Ladenson JH, Jaffe AS. Improved detection of cardiac contusion with cardiac troponin I Am Heart J. 1996; 131:308-12. 147813
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Jaffe AS, Landt Y, Parvin CA, Abendschein DR, Geltman EM, Ladenson JH. Comparative sensitivity of cardiac troponin I and lactate dehydrogenase isoenzymes for the diagnosing acute myocardial infarction Clin Chem. 1996; 42:1770-6. 147819
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Jaffe AS. Rationale for the use of conjunctive anticoagulation during thrombolysis. In Review in Depth Sobel BE Coron Art Dis. 1996; 7:491-6. 1232955
Fiedotin NA, Freedland KE, Carney RM, Skala JA, Rich MW, Jaffe AS. Depression, medical utilization in patients in chronic heart failure. Annuals of Behavioral Medicine. 1996:S134. 1137638
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Carney RM, Freedland KE, Eisen SA, Rich MW, Jaffe AS. Major depression and medication adherence in elderly patients with coronary artery disease Health Psychology. 1995; 14:88-90. 147815
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Carney RM, Saunders RD, Freedland KE, Stein P, Rich MW, Jaffe AS. Association of depression with reduced heart rate variability in coronary artery disease AJC. 1995; 76:562-4. 147818
Guest TM, Ramanathan AV, Schechtman KB, Ladenson JH, Jaffe AS. Myocardial injury in critically ill medical patients: A surprisingly frequent complication JAMA 49 1995 1945-19; 273:1945-9. 147812
Adams JE III, Schechtman K, Landt V, Landenson JH, Jaffe AS. Comparable detection of acute myocardial infarction by creatine kinase MB isoenzyme and cardiac troponin I Clin Chem 7 1994; 40:1291-5. 147809
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Adams JE, Sicard G, Allan BT, Bridwell KH, Lenke LG, Davila-Roman VG, Bodor GS, Ladenson JH, Jaffe AS. Diagnosis of perioperative myocardial infarction with masurement of cardiac troponin I N Engl J Med. 1994; 330:670-4. 147811
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Grant JW, Canter CE, Spray TL, Landt Y, Saffitz JE, Ladenson JH, Jaffe AS. Elevated donor cardiac troponin I: A marker of acute graft failure in infant heart recipients Circulation. 1994; 90:2618-21. 147814
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Lenke LG, Bridwel KH, Jaffe AS. Increase inc reatine kinase MB isoenzyme levels and spinal surgery J Spinal Disorders. 1994; 7:70-6. 147807
Adams JE 3rd, Bodor GS, Davila-Roman VG, Delmez JA, Apple FS, Ladenson JH, Jaffe AS. Cardiac troponin I. A marker with high specificity for cardiac injury. Circulation. 1993 Jul; 88(1):101-6. 147808
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Goldstein JA, Tweddell JS, Barzilai B, Yagi Y, Jaffe AS, Cox JL. Hemodynamic effects of atrial ineraction Cor ARt Dis. 1993; 4:545-53. 147805
Carney RM, Freedland KE, Rich MW, Smith LJ, Jaffe AS. Ventricular tachycardia and psychiatric depression in patients with coronary artery disease Am J Med. 1993; 95:23-8. 147806
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Jaffe AS. The use of antiarrhythmias in advanced cardiac life support. Ann Emerg Med. 1993; 22:307-16. 1232953
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Eisenberg MS, Aghababian RV, Bossaert L, Jaffe AS, Ornato JP, Weaver WD. Thrombolytic therapy. Ann Emerg Med. 1993; 22:417-27. 1137626
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Adams JE, Abendschein DR, Jaffe AS. Biochemical markers of myocardial injury: Is MB creatine kinase the choice for the 1990's? Circulation. 1993; 88:750-63. 1137632
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Jaffe AS, Landau WM. Clinical neuromythology XI death after death: The presumption of informed consent for CPR, ethical paradox, clinical conundrum. Neurology. 1993; 43:2173-8. 1137633
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Jaffe AS, Deedwania PC, Higginson LA, Boden WE, Mehta JL, Ferlinz J, Walsh RA, Sullivan JM, Vokonas PS, Cabin H, et al. Diagnostic and therapeutic implications: exploration through case discussions. Am J Cardiol. 1992 Nov 16; 70(16):45F-48F. 1874903
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Jaffe AS. The use of intravenous diltiazem in patients with acute coronary artery disease. Am J Cardiol. 1992; 69:25B-9B. 1137625
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Jaffe AS. Effects of diabetes on the heart. (Overview) Cor Artery Dis. 1992; 3:1-3. 1232952
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Eisenberg PR, Sobel BE, Jaffe AS. Activation of prothrombin accompanying thrombolysis with rt-PA JACC. 1992; 19:1065-9. 147802
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Goldstein JA, Tweddell JS, Barzilai B, Yagi Y, Jaffe AS, Cox JL. Importance of LV function and systolic ventricular interaction to right ventricular performance during acute right heart ischemia JACC. 1992; 19:704-11. 147803
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Freedland KE, CArney RM, Lustman PJ, Rich MW, Jaffe AS. Major depression in coronary artery disease, patients with versus without a prior history of depression Psychosomatic Med. 1992; 54:416-21. 147804
Adams JE, Siegel BA, Goldstein JA, Jaffe AS. Elevations of CK-MB following pulmonary embolism: A manifestation of occult right ventricular infarction Chest. 1992; 101:1203-6. 147793
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Goldstein JA, Kenzora JL, Jaffe AS. Coronary angiography with a novel mobile x-ray image intensifier Coronary ARtery Dis. 1992; 3:1065-71. 147796
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Jaffe AS, Emergency Cardiac Care Committee. Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiac Care JAMA. 1992; 268:2171-81. 149046
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Carney RM, Freedland KE, Smith LJ, Rich MW, Jaffe AS. Relation of depression and mortality after myocardial infarction in women. Circulation. 1992; 84:1876-77. 149015
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Eisenberg PR, Kenzora J, Sobel BE, Ludbrook PA, Jaffe AS. Relation between ST segment shifts during ischemia and thrombin activity in patients with unstable angina JACC. 1991; 18:893-903. 147799
Abendschein DA, Ellis AK, Eisenberg PR, Klocke FJ, Sobel BE, Jaffe AS. Prompt detection of coronary recanalization by analysis of rates of change of concentrations of macromolecular markers in plasma Cor ARt Dis. 1991; 2:201-12. 147797
Hartwell TD, Parker CB, Poole WK, Davis VG, Muller JE, Braunwald E, Robertson T, Rutherford J, Sobel BE, Strauss W, Thomas L, Roberts R, Jaffe AS, Willerson JT. Reproducibility of centralized laboratory interpretations of measures of myocardial infarct size, ventricular function, and ventricular electrical instability scintigraphy Coronary ARtery Disease. 1991; 2:997-84. 147787
Carney RM, Freedland KE, Jaffe AS. Altered circadian variation of acute myocardial infarction in patients with depression Coronary Artery Disease. 1991; 2:61-5. 147789
Goldstein JA, Tweddell JS, Barzilai B, Yagi Y, Jaffe AS, Cox JL. Right atrial ischemia exacerbates hemodynamic compromise associated with experimental right ventricular dysfunction JACC. 1991; 18:564-72. 147801
Scharp DW, Lacy PE, Santiago JV, McCullough CS, Weide LG, Boyle PJ, Falqui L, Marchetti P, Ricordi C, Gingerich RL, Jaffe AS, Cryer PE, Hanto DW, Anderson CB, Flye MW. Results of our first nine intraportal islet allografts in type I insulin dependent diabetic patients Transplantation. 1991; 51:76-85. 147795
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Cummins RO, Ornato JP, Thies WH, Pepe PE, Billi JE, Seidel J, Jaffe AS, Flint LS, Goldstein S, Abramson NS, Brown C, Chandra NC, Gonzalez ER, Newell L, Stults KR, Membrino GE. Improving survival from sudden cardiac arrest: The "Chain of Survival" Concept. Circulation. 1991; 83:1832-47. 1232951
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Jaffe AS. Automated defibrillation: A problem, a challenge and an opportunity - The role of Internists and cardiologists in the prehospital care of their patients Cont Intern Med 8-1 1990. 149058
Eisenberg PR, Lucore C, Kaufman L, Sobel BE, Jaffe AS, Rich S. Elevations of levels of fibrinopeptid A indicative of pulmonary vascular thrombosis in patient with primary pulmonary hypertension Circulation. 1990; 82:841-7. 147790
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Carney RM, Freedland KE, Jaffe AS. Insomnia and Depression Prior to Myocardial Infarction Psychosomatic Medicine. 1990; 52:603-9. 147791
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Carney RM, Freeland KE, Ludbrook PA, Saunders RD, Jaffe AS. Major depression, panic disorder, and mitral valve prolapse in patients who complainof chest pain Am J Med. 1990; 89:757-60. 147783
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Goldstein JA, Barzilai B, Rosamond TL, Eisenberg PR, Jaffe AS. Determinants of hemodynamic compromise with severe right ventricular infarction Circulation. 1990; 82:469-368. 147784
Eisenberg PR, Jaffe AS, Stump DC, Collen DJ, Bovill EG. Validity of enzyme-linked immunoabsorbent assays of cross-linked fibrin degradation products as a measure of clot lysis Circulation. 1990; 82:1159-68. 147785
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Barzilai B, Davis VG, Stone PH, Jaffe AS, MILIS study group. Prognostic significance fo mitral regurgitation in acute myocardial infarction AM J Cardiol. 1990; 65:1169-75. 147786
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Scharp DW, Lacy PE, Santiago JV, McCullough CS, Weide LG, Falqui L, Marchetti P, Gingerish RL, Jaffe AS, Cryer PE, Anderson CB, Flye MW. Insulin independence after Islet transplantation into Type I diabetic patient Diabetes. 1990; 39:515-18. 147788
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Cohen ML, Barzilai B, Gutierrez F, Jaffe AS, Eisenberg P. Treatment of prosthetic tricuspid valve thrombosis with low-dose tissue plasminogen activator. Am Heart J. 1990; 120:978-9. 147794
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Vered I, Vered Z, Perez JE, Jaffe AS, Whyte MP. Normal left ventricular function in children with x-linked hypophosphatemic rickets. A Doppler echocardiography study J Bone Min Res. 1990; 5:469-74. 147778
Cummins RO, Thies W, Paraskos J, Kerber RE, Billi JE, Seidel J, Jaffe AS, Flint L, Ornato JP, Abramson NS, Brown C, Chandra NC, Gonzales ER, Newell L, Stults KR, Membrino GE, Pepe PE. Encouraging early defibrillation: The American Heart Association and automated external defibrillation. Ann Emerg Med. 1990; 19:1245-8. 1232950
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Carney RM, Freedland KE, Sapira JD, Jaffe AS. Panic disorder and depression in patients with chest pain not due to coronary artery disease. Am J Cardiol (letter) 1990; 15:1048. 1232960
Vered I, Vered Z, Perez JE, Jaffe AS, Whyte MP. Normal left ventricular performance documented by Doppler echocardiography in patients with longstanding hypocalcemia AM J Med. 1989; 86:413-6. 147779
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Eisenberg PR, Shaw D, Schaab C, Jaffe AS. Concordance of creatine kinase-MB activity and mass Clin Chem. 1989; 35:440-3. 147780
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Carney RM, Freedland K, Rich MW, Jaffe AS. Stimulus induced analgesia and silent myocardial ischemia. J Appl Cardiol. 1989; 4:271-4. 147782
Stone PH, Muller JE, Hartwell T, York BJ, Rutherford JD, Parker CB, Turi ZG, Strauss WH, Willerson JT, Sobel BE, Robertson T, Passamani E, Braunwald E, Jaffe AS, MILIS Study Group. The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: Contribution of both coronary disease and diastolic left ventricular dysfunction to the adverse prognosis J Am Coll Cardiol. 1989; 14:49-57. 147775
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Devries S, Jaffe AS, Geltman EM, Sobel BE, Abendschein D. Enzymatic estimation of the extent of irreversible myocardial injury early after reperfusion. Am Heart J. 1989; 117:31-6. 147765
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Jaffe AS, TIMI study group. Comparison of invaasive and conservative strategies after treatment with intravenous tissue plasminogen activator in acute myocardial infarction - Results of the thrombolysis in myocardial infarction (TIMI) phase II trial N Engl J Med. 1989; 320:618-27. 149038
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Jaffe AS. Cardiovascular effects of diabetes. Curr Opin in Cardiol. 1989; 4:711-20. 1232949
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Kennedy JW, Atkins JM, Goldstein S, Jaffe AS, McIntyre KM, Mueller HS, Paraskos JA, Weaver WD. Recent changes in management of acute myocardial infarction: Implications for Emergency Care Physicians. J Am Coll Cardiol. 1988; 11:446-9. 1232947
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Eisenberg PR, Sobel BE, Jaffe AS. Characterization In Vivo of the fibrin specificity of activators of the fibrinolytic system. Circulation. 1988; 78:592-7. 1137580
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Eisen HJ, Barzilai B, Jaffe AS, Geltman EM. Relationship of QRS scoring system to enzymatic and pathologic infarct size: The role of infarct location. Am Heart J. 1988; 115:993-1001. 147766
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Muller JE, Rude RE, Baunwald E, Hartwell TD, Roberts R, Sobel BE, Ritter C, Parker CB, Jaffe AS, Stone PH, Raabe DS, Willerson JT, Robertson T, MILIS study group. Myocardial infarct extension: Incidence, outcome, and risk factors in the MILIS study. Ann Intern Med. 1988; 108:1-6. 147767
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Eisenberg PR, Miletich JP, Sobel BE, Jaffe AS. Differential effects of activation of prothrombin by streptokinase compared with urokinase and tissue-type plasminogen activator (t-PA). Thrombosis Res. 1988; 50:707-17. 147770
Rao AK, Pratt C, Berke A, Jaffe AS, Ockene I, Schreiber TL, Bell Knatterud G, Robertson TL, Terrin ML, for the TIMI Investigators. The thrombolysis in myocardial infarction trial - Phase I. Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase J Am Col Cardiol. 1988; 11:1-11. 147771
Seacord LM, Abendschein DR, Nohara R, Hartzler G, Sobel BE, Jaffe AS. Detection of reperfusion within one hour after coronary recanalization by analysis of isoforms of the MM creatine kinase isoenzyme in plasma Fibrinolysis. 1988; 2:151-6. 147772
Nohara R, Sobel BE, Jaffe AS, Abendschein DR. Quantitative analysis of isoforms of creatine kinase MM in plasma by chromatofocusing with on-line monitoring of enzyme activity Clin Chem 2 1988; 34:235-9. 147773
Lee RT, Lee TH, Poole WK, Gustafson N, Stone PH, Jaffe AS, Muller JE, Sobel BE, Braunwald E, MILIS study group. Rate of disappearance of creatine kinase and creatine kinase-MB after acute myocardial infarction. Clinical determinants of variability Am Heart J. 1988; 116:661-4. 147776
Abendschein D, Seacord LM, Nohara R, Sobel BS, Jaffe AS. Prompt detection of myocardial injury by assay of creatine kinase isoforms in initial plasma samples Clin Cardiol. 1988; 11:661-4. 147777
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Jaffe AS, Safdar S, Barzilai B, Semenkovich J, Saffitz J. Clinical Pathologic Conference: Carcinoma of the cervix with metastasis to the heart. Am J Med. 1988; 84:463-74. 149000
Jaffe AS, TIMI research group. Immediate versus delayed catheterization and angioplasty following thrombolytic therapy for acute myocardial infarction - TIMI IIA results. J Am Med Assoc. 1988; 260:2849-58. 149037
Eisenberg PR, Sherman LA, Perez J, Jaffe AS. Relationship between elevated plasma levels of crosslinked fibrin degradation products (XL-FDP) and the clinical presentation of patients with myocardial infarction. Thromb Res. 1987; 46:109-20. 147755
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Gessler CJ, Jaffe AS. Hemodynamic monitoring and pacing with one catheter: A pilot study. Cath and Cardiovasc Diag. 1987; 13:141-4. 147756
Eisenberg PR, Sherman LA, Tiefenbrunn AJ, Ludbrook PA, Sobel BS, Jaffe As. Sustained fibrinolysis after administration of t-PA despite ist short half life in the circulation. Thromb and Hemostasis. 1987; 57:35-40. 147757
Tofler GH, Stone PH, Muller JE, Willich SN, Davis VKL, Poole WK, Strauss W, Willerson JT, Sobel BE, Jaffe AS, Robertson T, Passamani E, Braunwald E, MILIS study group. Effects of gender and race on prognosis after myocardial infarction: Adverse prognosis for women particularly black women. J Am Coll Cardiol. 1987; 9:473-82. 147758
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Cox DA, Stone PH, Muller JE, Parker C, Hartwell TD, Rutherford JD, Roberts R, Jaffe AS, Hackel DB, Passamani E, Robertson T, Sobel BE, Willerson JT, Braunwald E, MILIS study group. Prognostic implications of an early peak in plasma MB creatine kinase patients with acute myocardial infarction. J Am Coll Cardiol. 1987; 10:979-90. 147759
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Eisenberg PR, Sherman LA, Jaffe AS. Paradoxical elevation of fibrinopeptide A after streptokinase: Evidence for continued thrombosis despite intense fibrinolysis. JACC. 1987; 10:527-9. 147760
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Jaffe AS, Biello DR, Sobel BE, Geltman EM. Enhancement of metabolism of jeopardized myocardium by nifedipine. Intern J Cardiol. 1987; 15:77-89. 147761
Abendschein DR, Serota H, Plummer TH Jr, Amiraian K, Strauss AW, Sobel BE, Jaffe AS. Conversion of MM creatine kinase isoforms in human plasma by carboxypeptidase. N J Lab Clin Med. 1987; 110:798-806. 147762
Carney RM, Rich M, teVelde A, Saini J, Clark K, Jaffe AS. Major depression disorder: A common psychiatric disorder in patients with coronary artery disease. Am J Cardiol. 1987; 60:1273-5. 147763
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Barzilai B, Gessler C, Perez JE, Schaab C, Jaffe AS. Significance of Doppler detected mitral regurgitation acute myocardial infarction. Am J Cardiol. 1987; 61:220-3. 147764
Jaffe AS, Sobel BE. Thrombolysis with tissue-type plasminogen activator in acute myocardial infarction. Potentials and pitfalls. JAMA. 1986 Jan 10; 255(2):237-9. 1232942
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Genton R, Jaffe AS. Management of congestive heart failure in patients with acute myocardial infarction. JAMA. 1986; 256:2556-60. 1232943
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Jaffe AS. The state of the art of myocardial infarction. Circulation (Suppl) -IV-123 1986; 74:IV-120. 1232944
Jaffe AS. Cardiovascular Pharmacology I. Circulation ( 74 IV-7-IV-74 1986; Suppl). 1232946
Eisenberg PR, Sherman L, Rich M, Schwartz D, Schechtman K, Geltman EM, Sobel BE, Jaffe AS. Importance of continued activation of thrombin reflected by fibrinopeptides A to the efficacy of thrombolysis. JACC. 1986; 7:1255-62. 1232914
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Turi ZG, Stone PH, Muller JE, Parker C, Rude RE, Raabe DE, Jaffe AS, Hartwell TD, Robertson TL, Braunwald E, MILIS Study Group. Implications for acute intervention of time of hospital arrival of patients with acute mycocardial infarction. Am J Cardiol. 1986; 58:203-9. 1137573
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Muller JE, Turi ZG, Stone PH, Rude RE, Raabe DS, Jaffe AS, Gold HK, Gustafson N, Poole WK, Passamani E, Smith TW, Braunwald E, MILIS Study Group. Digoxin therapy and mortality following myocardial infarction: Experience in the MILIS study. N Eng J Med. 1986; 314:265-71. 147745
Croft HC, Rude RE, Gustafson N, Stone PH, Poole WK, Roberts R, Strauss HW, Raabe DS, Thomas LJ, Jaffe AS, Muller J, Hoagland P, Sobel BE, Passamani ER, Braunwald E, Willerson JT, MILIS Study Group. Abrupt beta-blockade withdrawal in patients with acute myocardial infarction. Effects on infarct size, left ventricular function, and hospital course. Circulation. 1986; 73:1281-90. 147747
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Wheelan K, Mukharji J, Rude RE, Poole WK, Gustafson N, Thomas LJ, Strauss HW, Jaffe AS, Muller JE, Roberts R, Croft CH, Passamani E, Willerson JT, MILIS Study Group. Sudden death and its relationship to QT interval prolongation following acute myocardial infarction (2-year follow-up). Am J Cardiol. 1986; 57:745-50. 147749
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Stone PH, Turi ZG, Muller JE, Parker C, Hartwell T, Rutherford JD, Jaffe AS, Raabe DS, Passamani ER, Willerson JT, Sobel BE, Robertson TL, Braunwald E, MILIS study group. Prognostic significance of the exercise treadmill test performance six months after myocardial infarction. J Am Coll Cardiol. 1986; 8:1007-17. 147750
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Jaffe AS, Serota H, Grace A, Sobel BE. Diagnostic changes in plasma creatine kinase isoforms early after the onset of acute myocardial infarction. Circulation. 1986; 74:105-9. 147751
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Spadaro JJ, Ludbrook PA, Tiefenbrunn AJ, Kurnik PB, Jaffe AS. Paucity of subtle myocardial injury after angioplasty delineated with MB CK. Cath and Cardiovasc Dis. 1986; 12:230-4. 147752
Jaffe AS, MILIS study group. Hyaluronidase therapy for acute myocardial infarction: Results of a randomized, blinded, multicenter trial. Am J Cardiol. 1986; 57:1236-43. 149036
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Jaffe AS, Montgomery WH, Donegan J, McIntyre KM, et al. 1985 National Conference on Standards and Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiac Care. JAMA. 1986; 255:2843-989. 149041
Pierce GF, Eds, Chan KM, Ladenson JH, Discussant, Jaffe AS. Increased creatine kinase MB isoenzyme in the absence of acute myocardial infarction. Clin Chemistry group. 1986; 32:2044-51. 148999
Turi ZG, Rutherford JD, Roberts R, Muller JE, Jaffe AS, Rude RE, Parker C, Raabe DS, Stone PH, Hartwell TD, et al. Electrocardiographic, enzymatic and scintigraphic criteria of acute myocardial infarction as determined from study of 726 patients (A MILIS Study). Am J Cardiol. 1985 Jun 1; 55(13 Pt 1):1463-8. 2121121
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Jaffe AS, TIMI Study Group. The thrombolysis in myocardial infarction (TIMI) trial - Phase I findings N Engl J Med. 1985; 312:932-6. 149035
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Lamas GA, Muller JE, Turi ZG, Stone PH, Rutherford JD, Jaffe AS, Raabe DS, Rude RE, Mark DB, Califf RM, Gold HK, Robertson T, Passamani ER, Braunwald E, MILIS study group. A simplified method to predict the occurence of complete heart block during acute myocardial infarction Am J Cardiol. 1985; 57:1213-9. 147753
Eisenberg PR, Lee RG, Biello DR, Geltman EM, Jaffe AS. Chest pain after nontransmural infarction: The absence of remediable coronary vasospasm. Am Heart J. 1985; 11:515-31. 147740
Semenkovich CF, Jaffe AS. Adverse effects due to morphine sulfate: A challenge to previous clinical doctrine Am J Med. 1985; 79:325-30. 147741
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Jansen DE, Corbett JR, Lewis SE, Wolfe CL, Gabliani G, Filipchuk N, Redish G, Parkey RW, Buja M, Jaffe AS, Sobel BS, Willerson JT. Measurement of myocardial infarct size: A comparison of single photon emission computed tomography with pyrophosphate and serial CK-MB measurements Circulation. 1985; 72:237-333. 147742
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Eisenberg PE, Sherman LA, Schechtman K, Sobel BE, Jaffe AS. Fibrinopeptide A: A marker of acute coronary thrombosis Circulation. 1985; 71:912-8. 147743
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Jaffe AS, Spadaro JJ, Schechtman K, Robert R, Geltman EM, Sobel BE. Increased congestive heart failure after infarction of modest extent in patients with diabetes mellitus. Am Heart J. 1984; 108:31-7. 1311669
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Shafer KE, Santoro SA, Sobel BE, Jaffe AS. Monitoring activity of fibrinolytic therapy: A therapeutic challenge. Am J Med. 1984; 75:879-86. 1232941
Hackel DB, Reimer KA, Ideker RE, Mikat EM, Hartwell TD, Parker CB, Braunwald EB, Gold HK, Jaffe AS, Raabe DS, Rude RE, Sobel BE, Stone PH, Buja M, Muller JE, Roberts R, MILIS Study Group. Comparison of enzymatic, anatomic estimates of myocardial infarct in man. Circulation. 1984; 70:824-35. 1137572
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Sedlis S, Saffitz J, Schwob V, Jaffe AS. Cardiac amyloidosis simulating hypertrophic myopathy. Am J Cardiol. 1984; 53:969-70. 148996
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Jaffe AS, Ritter C, Meltzer V, Harter H, Roberts R. Unmasking artifactural increases in creatine kinase isoenzymes in patients with renal failure J Lab Clin Med. 1984; 104:193-202. 147733
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Eisenberg PR, Jaffe AS, Schuster DP. Clinical evaluation compared to pulmonary artery catheterization in the hemodynamic assessment of critically-ill patients Crit Care Med. 1984; 12:549-52. 147734
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Roberts R, Croft C, Gold HK, Tyler DH, Jaffe AS, Muller JE, Mullin SM, Parker C, Passamani ER, Poole WK, Raabe DS, Rude RE, Stone PH, Turi G, Sobel BE, Willerson JT, Braunwald E, MILIS Study Group. Effect of propranolol on myocardial infarct size in a randomized, blinded, multicenter trial N Engl J Med. 1984; 311:218-25. 147735
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Sobel BE, Geltman EM, Tiefenbrunn AJ, Jaffe AS, Spadaro JJ, Ter-Pogossian MM, Collen D, Ludbrook PA. Improved regional myocardial metabolism after coronary thrombolysis iwth tissue-type plasminogen activator (t-PA) or streptokinase Circulation. 1984; 69:983-9. 147736
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Jaffe AS, Lee R, Perez J, Geltman EM, Wilner G, Sobel BE. Lack of elevation of platelet factor IV in plasma from patient with myocardial infarction J Am Coll Cardiol. 1984; 4:653-9. 147737
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Rosenblum AM, Ludbrook PA, Jaffe AS. Significance of elevated MB creatine kinase in patients after cardiac catheterization. Cardiac Catheter Diagn. 1984; 10:547-52. 147739
Jaffe AS, Garfinkel BT, Ritter CS, Sobel BE. Plasma, MB creatine kinase after vigorous exercise in professional athletes Am J Cardiol. 1984; 53:856-8. 147730
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Mukharji J, Rude RE, Poole KW, Thomas LJ, Strauss HW, Jaffe AS, Muller JE, Roberts R, Raabe DS, Croft CH, Passamani E, Braunwald E, Willerson JT the MILIS Study Group. Late sudden death following acute myocardial infarction: Multivariate analysis of risk factors Am J Cardiol. 1984; 54:31-6. 147731
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Stone PH, Muller JE, Turi ZG, Geltman E, Jaffe AS, Braunwald E. Efficacy of nifedipine therapy in patients with refractory angina pectoris: Significance of the presence of coronary vasospasm Am Heart J. 1983; 106:644-52. 147732
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Jaffe AS, Geltman EM, Tiefenbrunn AJ, Ambos HD, Strauss H, Sobel BE, Roberts R. Reduction in infarct size in patient with inferior infarction with intravenous nitroglycerin. A randomized prospective study. Br Heart J. 1983; 49:452-69. 147727
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Billadello JJ, Smith JL, Ludbrook PA, Tiefenbrunn AJ, Jaffe AS, Sobel BE, Geltman EM. The implications of "Reciprocal" ST segment depression associated with acute myocardial infarction identified by positron tomography J Am Coll Cardiol. 1983; 2:616-24. 147729
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Klahr S, Jaffe AS, McKeel T. Cyanotic Feet and Renal Failure in a 67-year-old man Am J Med. 1983; 75:509-17. 148994
Stone PH, Muller JE, Turi ZG, Geltman E, Jaffe AS, Braunwald E. Efficacy of nifedipine therapy in patients with refractory angina pectroris: Significance of the presence of coronary vasospasm. Arq Bras Cardiol. 1983; 41:469-76. 1137579
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Gutierrez FR, McKnight RC, Jaffe AS, Ludbrook PA, Biello D, Weldon CS. Double porcine valve replacement in carcinoid heart disease: A case report. Chest. 1982; 181:101. 148990
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Jaffe AS, Robert R. Use of intravenous nitroglycerin in cardiovascular disease. Pharmacotherapy. 1982; 2(5):273-8. 148993
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Clark KW, Geltman EM, Miller JP, Moore P, Madden KA, Thomas JJ, Hartwell TD, Jaffe AS, Rabbe DS, Stone PH, Gold HK, Rude RE, the MILIS Study Group. Reproducibility of dysrhythmia findings by a centralized laboratory within a major multicenter trial. 1982 Proceeding of Computers in Cardiology, Seattle, Washington. 1982. 1137571
Jaffe AS, Geltman EM, Rodey GE, Uitto J. Mitral valve prolapse:A consistent manifestation of type IV Ehlers-Danlos Syndrome (the pathogenic role of abnormal type III collagen synthesis). Circulation. 1981; 64:121. 147726
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Kornfeld S, Hruska K, Berger N, Jaffe AS, Shields H, DeSchriver K. Gastric outlet obstruction in patients with multiple myeloma. Am J Med. 1980; 68:141-48. 148988
Jaffe AS, Klein MS, Patel BR, Siegel BA, Roberts R. Abnormal technetium-99m pyrophosphate images in unstable angina: Ischemia versus infarction? Am J Cardiol. 1979; 44:1035. 147725
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Ahumada GG, Karlsberg RP, Jaffe AS, Ambos HD, Sobel BE, Roberts R. Reduction of early ventricular arrhythmias by acebutolol in patients with acute myocardial infarction Br Heart J. 1979; 41:654. 147723
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Srebro R, Jaffe AS. The origin of dark noise in foveal vision. J Optical Soc Am. 1968; 58:1313. 147724

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