Publications

1. Shanafelt TD, Ramsay AG, Zent CS, Leis JF, Tun HW, Call TG, Laplant B, Bowen D, Pettinger A, Jelinek DF, Hanson CA, Kay NE. Long-term repair of T-cell synapse activity in a phase II trial of chemoimmunotherapy followed by lenalidomide consolidation in previously untreated chronic lymphocytic leukemia (CLL). Blood. 2013 May 16; 121(20):4137-41. Epub 2013 Mar 14. 2311187
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2. von Roemeling CA, Marlow LA, Wei JJ, Cooper SJ, Caulfield TR, Wu K, Tan WW, Tun HW, Copland JA. Stearoyl-CoA desaturase 1 is a novel molecular therapeutic target for clear cell renal cell carcinoma. Clin Cancer Res. 2013 May 1; 19(9):2368-80. Epub 2013 Apr 30. 2320450
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3. Cooper SJ, von Roemeling CA, Kang KH, Marlow LA, Grebe SK, Menefee ME, Tun HW, Colon-Otero G, Perez EA, Copland JA. Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers. Mol Cancer Ther. 2012 Oct; 11(10):2105-15. Epub 2012 Jul 23. 2259367
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4. Marlow LA, von Roemeling CA, Cooper SJ, Zhang Y, Rohl SD, Arora S, Gonzales IM, Azorsa DO, Reddi HV, Tun HW, Doppler HR, Storz P, Smallridge RC, Copland JA. Foxo3a drives proliferation in anaplastic thyroid carcinoma through transcriptional regulation of cyclin A1: a paradigm shift that impacts current therapeutic strategies. J Cell Sci. 2012 Sep 15; 125(Pt 18):4253-63. Epub 2012 Jun 20. 2282310
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5. Khurana A, Tun HW, Marlow L, Copland JA, Dredge K, Shridhar V. Hypoxia negatively regulates heparan sulfatase 2 expression in renal cancer cell lines. Mol Carcinog. 2012 Jul; 51(7):565-75. Epub 2011 Jul 07. 2175023
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6. Li Z, Caulfield T, Qiu Y, Copland JA, Tun HW. Pharmacokinetics of bendamustine in the central nervous system: Chemoinformatic screening followed by validation in a murine model. MedChemComm. 2012; 3(12):1526-30. 2290303
   
7. Jiang L, Li Z, Finn LE, Personnet DA, Edenfield B, Foran JM, Jaeckle KA, Reimer R, Menke DM, Ketterling RP, Tun HW. Primary central nervous system B cell lymphoma with features intermediate between diffuse large B cell lymphoma and Burkitt lymphoma. Int J Clin Exp Pathol. 2012; 5(1):72-6. Epub 2012 Jan 01. 2230308
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8. Li Z, Kamon T, Personett DA, Caulfield T, Copland JA, Yoshimitsu T, Tun HW. Pharmacokinetics of Agelastatin A in the central nervous system. MedChemComm. 2012; 3(2):233-7. 2232251
   
9. Cooper SJ, Tun HW, Roper SM, Kim Y, Kislinger T, Drake RR, Copland JA. Current status of biomarker discovery in human clear cell renal cell carcinoma. J Mol Biomark Diagn. 2012. 2261838
   
10. Vishnu P, Jiang L, Cortese C, Menke DM, Tun HW. Plasmacytoma-like posttransplant lymphoproliferative disorder following orthotopic liver transplantation: a case report. Transplant Proc. 2011 Sep; 43(7):2806-9. 2190782
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11. Cooper SJ, Zou H, Legrand SN, Marlow LA, von Roemeling CA, Radisky DC, Wu KJ, Hempel N, Margulis V, Tun HW, Blobe GC, Wood CG, Copland JA. Loss of type III transforming growth factor-beta receptor expression is due to methylation silencing of the transcription factor GATA3 in renal cell carcinoma. Oncogene. 2010 May 20; 29(20):2905-15. Epub 2010 Mar 08. 2155586
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12. Shetty RK, Adams BH, Tun HW, Runyan BR, Menke DM, Broderick DF. Use of rituximab for periocular and intraocular mucosa-associated lymphoid tissue lymphoma. Ocul Immunol Inflamm. 2010 Apr; 18(2):110-2. 1997992
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13. Jiang L, Marlow LA, Cooper SJ, Roemeling CV, Menke DM, Copland JA, Tun HW. Selective central nervous system tropism of primary central nervous system lymphoma. Int J Clin Exp Pathol. 2010; 3(8):763-7. Epub 2010 Oct 08. 2136157
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14. Tun HW, Marlow LA, von Roemeling CA, Cooper SJ, Kreinest P, Wu K, Luxon BA, Sinha M, Anastasiadis PZ, Copland JA. Pathway signature and cellular differentiation in clear cell renal cell carcinoma. PLoS One. 2010; 5(5):e10696. Epub 2010 May 18. 2265799
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15. Shanafelt TD, Bowen DA, Venkat C, Slager SL, Zent CS, Kay NE, Reinalda M, Tun H, Sloan JA, Call TG. The physician-patient relationship and quality of life: lessons from chronic lymphocytic leukemia. Leuk Res. 2009 Feb; 33(2):263-70. Epub 2008 Jul 25. 1960111
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16. Zubair AC, Grant R, Wu W, Tun H, Rivera C, Moreno-Aspitia A, Joyce M, Roy V, Colon-Otero G, Solberg LA. Platelet count is a sensitive predictor of autologous peripheral blood progenitor cell collection yield in previously treated plasma cell disease patients. Transfusion. 2008 Jun; 48(6):1106-14. Epub 2008 Feb 25. 1898778
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17. Tun HW, Personett D, Baskerville KA, Menke DM, Jaeckle KA, Kreinest P, Edenfield B, Zubair AC, O'Neill BP, Lai WR, Park PJ, McKinney M. Pathway analysis of primary central nervous system lymphoma. Blood. 2008 Mar 15; 111(6):3200-10. Epub 2008 Jan 09. 1874230
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18. Zou YS, Fink SR, Stockero KJ, Paternoster SF, Smoley SA, Tun HW, Reeder CB, Tefferi A, Dewald GW. Efficacy of conventional cytogenetics and FISH for EGR1 to detect deletion 5q in hematological disorders and to assess response to treatment with Lenalidomide. Leuk Res. 2007 Sep; 31(9):1185-9. Epub 2006 Nov 27. 1834768
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19. Tun HW, Wallace KH, Grinton SF, Khoor A, Burger CD. Etanercept therapy for late-onset idiopathic pneumonia syndrome after nonmyeloablative allogeneic hematopoietic stem cell transplantation. Transplant Proc. 2005 Dec; 37(10):4492-6. 1743686
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20. Tun HW, Krishna M, Menke DM. Hepatitis C-related posttransplant plasma cell proliferative disorder with hepatitis C virus in neoplastic plasma cells: a new posttransplant disease entity? Transplant Proc. 2004 Nov; 36(9):2692-6. 1677610
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21. Tun H, Marlow L, Pinnix I, Kinsey R, Sambamurti K. Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway. J Mol Neurosci. 2002 Aug-Oct; 19(1-2):31-5. 1315255
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22. Pinnix I, Musunuru U, Tun H, Sridharan A, Golde T, Eckman C, Ziani-Cherif C, Onstead L, Sambamurti K. A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor. J Biol Chem. 2001 Jan 5; 276(1):481-7. 1003561
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