Publications

  1. Konopka AR, Sreekumaran Nair K. Mitochondrial and skeletal muscle health with advancing age. Mol Cell Endocrinol. 2013 May 16. [Epub ahead of print] 2324781
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  2. Johnson ML, Robinson MM, Nair KS. Skeletal muscle aging and the mitochondrion. Trends Endocrinol Metab. 2013 May; 24(5):247-56. Epub 2013 Feb 01. 2300869
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  3. Lanza IR, Blachnio-Zabielska A, Johnson ML, Coenen-Schimke JM, Jakaitis DR, Lebrasseur NK, Jensen MD, Nair KS, Zabielski P. Influence of Fish Oil on Skeletal Muscle Mitochondrial Energetics and Lipid Metabolites during High-Fat Diet. Am J Physiol Endocrinol Metab. 2013 Apr 30. [Epub ahead of print] 2325506
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  4. Renaud G, Llano-Diez M, Ravara B, Gorza L, Feng HZ, Jin JP, Cacciani N, Gustafson AM, Ochala J, Corpeno R, Li M, Hedstrom Y, Ford GC, Nair KS, Larsson L. Sparing of muscle mass and function by passive loading in an experimental intensive care unit model. J Physiol. 2013 Mar 1; 591(Pt 5):1385-402. Epub 2012 Dec 24. 2311020
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  5. Zabielski P, Ford GC, Persson XM, Jaleel A, Dewey JD, Nair KS. Comparison of different mass spectrometry techniques in the measurement of L-[ring-(13)C6]phenylalanine incorporation into mixed muscle proteins. J Mass Spectrom. 2013 Feb; 48(2):269-75. 2300876
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  6. McCoy RG, Nair KS. The 2010 ESPEN Sir David Cuthbertson Lecture: New and old proteins: Clinical implications. Clin Nutr. 2013 Jan 18. [Epub ahead of print] 2309911
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  7. Lanza IR, Zabielski P, Klaus KA, Morse DM, Heppelmann CJ, Bergen HR 3rd, Dasari S, Walrand S, Short KR, Johnson ML, Robinson MM, Schimke JM, Jakaitis DR, Asmann YW, Sun Z, Nair KS. Chronic caloric restriction preserves mitochondrial function in senescence without increasing mitochondrial biogenesis. Cell Metab. 2012 Dec 5; 16(6):777-88. 2289339
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  8. Short KR, Irving BA, Basu A, Johnson CM, Nair KS, Basu R. Effects of type 2 diabetes and insulin on whole-body, splanchnic, and leg protein metabolism. J Clin Endocrinol Metab. 2012 Dec; 97(12):4733-41. Epub 2012 Oct 02. 2273991
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  9. Barazzoni R, Short KR, Asmann Y, Coenen-Schimke JM, Robinson MM, Nair KS. Insulin fails to enhance mTOR phosphorylation, mitochondrial protein synthesis, and ATP production in human skeletal muscle without amino acid replacement. Am J Physiol Endocrinol Metab. 2012 Nov 1; 303(9):E1117-25. Epub 2012 Sep 11. 2294151
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  10. Bush NC, Basu R, Rizza RA, Nair KS, Khosla S, Jensen MD. Insulin-mediated FFA suppression is associated with triglyceridemia and insulin sensitivity independent of adiposity. J Clin Endocrinol Metab. 2012 Nov; 97(11):4130-8. Epub 2012 Aug 29. 2267977
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  11. Chow LS, Seaquist ER, Eberly LE, Mashek MT, Schimke JM, Nair KS, Mashek DG. Acute free fatty acid elevation eliminates endurance training effect on insulin sensitivity. J Clin Endocrinol Metab. 2012 Aug; 97(8):2890-7. Epub 2012 May 25. 2247745
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  12. Gonzalez F, Nair KS, Daniels JK, Basal E, Schimke JM, Blair HE. Hyperandrogenism sensitizes leukocytes to hyperglycemia to promote oxidative stress in lean reproductive-age women. J Clin Endocrinol Metab. 2012 Aug; 97(8):2836-43. Epub 2012 May 08. 2243822
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  13. Johnson ML, Nair KS. Assessment of old and new proteins: A novel methodology. Nutr Metab Cardiovasc Dis. 2012 Jul 09. [Epub ahead of print] 2257345
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  14. Soop M, Nehra V, Henderson GC, Boirie Y, Ford GC, Nair KS. Coingestion of whey protein and casein in a mixed meal: demonstration of a more sustained anabolic effect of casein. Am J Physiol Endocrinol Metab. 2012 Jul 1; 303(1):E152-62. Epub 2012 May 08. 2256138
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  15. Irving BA, Robinson MM, Nair KS. Age effect on myocellular remodeling: response to exercise and nutrition in humans. Ageing Res Rev. 2012 Jul; 11(3):374-89. Epub 2011 Nov 07. 2206833
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  16. McCoy RG, Irving BA, Soop M, Srinivasan M, Tatpati L, Chow L, Weymiller AJ, Carter RE, Nair KS. Effect of insulin sensitizer therapy on atherothrombotic and inflammatory profiles associated with insulin resistance. Mayo Clin Proc. 2012 Jun; 87(6):561-70. 2250002
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  17. Giannoulis MG, Martin FC, Nair KS, Umpleby AM, Sonksen P. Hormone replacement therapy and physical function in healthy older men. Time to talk hormones? Endocr Rev. 2012 Jun; 33(3):314-77. Epub 2012 Mar 20. 2235247
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  18. Nemutlu E, Juranic N, Zhang S, Ward LE, Dutta T, Nair KS, Terzic A, Macura S, Dzeja PP. Electron spray ionization mass spectrometry and 2D 31P NMR for monitoring 18O/16O isotope exchange and turnover rates of metabolic oligophosphates. Anal Bioanal Chem. 2012 May; 403(3):697-706. Epub 2012 Mar 18. 2235296
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  19. Dutta T, Chai HS, Ward LE, Ghosh A, Persson XM, Ford GC, Kudva YC, Sun Z, Asmann YW, Kocher JP, Nair KS. Concordance of changes in metabolic pathways based on plasma metabolomics and skeletal muscle transcriptomics in type 1 diabetes. Diabetes. 2012 May; 61(5):1004-16. Epub 2012 Mar 13. 2246457
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  20. Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, Leinwand LA, Spiegelman BM. A PGC-1alpha isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 2012; 151(6):1319-31. 2293410
  21. Di Camillo B, Irving BA, Schimke J, Sanavia T, Toffolo G, Cobelli C, Nair KS. Function-based discovery of significant transcriptional temporal patterns in insulin stimulated muscle cells. PLoS One. 2012; 7(3):e32391. Epub 2012 Mar 01. 2235764
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  22. Gonzalez F, Nair KS, Daniels JK, Basal E, Schimke JM. Hyperandrogenism sensitizes mononuclear cells to promote glucose-induced inflammation in lean reproductive-age women. Am J Physiol Endocrinol Metab. 2012; 302(3):297-306. 2228561
  23. Nair KS. Changing of the guards. Diabetes. 2012; 61(1):1-3. 2221523
  24. Lanza IR, Bhagra S, Nair KS, Port JD. Measurement of human skeletal muscle oxidative capacity by 31P-MR spectroscopy: a cross-validation with in vitro measurements. J Magn Reson Imaging. 2011 Nov; 34(5):1143-50. 2199643
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  25. Singh M, Rihal CS, Lennon RJ, Spertus JA, Nair KS, Roger VL. Influence of frailty and health status on outcomes in patients with coronary disease undergoing percutaneous revascularization. Circ Cardiovasc Qual Outcomes. 2011 Sep; 4(5):496-502. Epub 2011 Aug 30. 2187680
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  26. Irving BA, Short KR, Nair KS, Stump CS. Nine days of intensive exercise training improves mitochondrial function but not insulin action in adult offspring of mothers with type 2 diabetes. J Clin Endocrinol Metab. 2011 Jul; 96(7):E1137-41. Epub 2011 Apr 20. 2160158
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  27. Ochala J, Gustafson AM, Diez ML, Renaud G, Li M, Aare S, Qaisar R, Banduseela VC, Hedstrom Y, Tang X, Dworkin B, Ford GC, Nair KS, Perera S, Gautel M, Larsson L. Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms. J Physiol. 2011 Apr 15; 589(Pt 8):2007-26. Epub 2011 Feb 14. 2164030
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  28. Irving BA, Nair KS, Srinivasan M. Effects of insulin sensitivity, body composition, and fitness on lipoprotein particle sizes and concentrations determined by nuclear magnetic resonance. J Clin Endocrinol Metab. 2011 Apr; 96(4):E713-8. Epub 2011 Jan 26. 2147360
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  29. Vendelbo MH, Nair KS. Mitochondrial longevity pathways. Biochim Biophys Acta. 2011 Apr; 1813(4):634-44. Epub 2011 Feb 02. 2162116
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  30. Rostambeigi N, Lanza IR, Dzeja PP, Deeds MC, Irving BA, Reddi HV, Madde P, Zhang S, Asmann YW, Anderson JM, Schimke JM, Nair KS, Eberhardt NL, Kudva YC. Unique cellular and mitochondrial defects mediate FK506-induced islet beta-cell dysfunction. Transplantation. 2011 Mar 27; 91(6):615-23. 2141508
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  31. Nair KS, Irving BA, Lanza IR. Can dietary nitrates enhance the efficiency of mitochondria? Cell Metab. 2011 Feb 2; 13(2):117-8. 2147415
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  32. Koutsari C, Basu R, Rizza RA, Nair KS, Khosla S, Jensen MD. Nonoxidative free fatty acid disposal is greater in young women than men. J Clin Endocrinol Metab. 2011 Feb; 96(2):541-7. Epub 2010 Dec 01. 2129756
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  33. Muniyappa R, Irving BA, Unni US, Briggs WM, Nair KS, Quon MJ, Kurpad AV. Limited predictive ability of surrogate indices of insulin sensitivity/resistance in Asian-Indian men. Am J Physiol Endocrinol Metab. 2010 Dec; 299(6):E1106-12. Epub 2010 Oct 13. 2136382
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  34. Jaleel A, Henderson GC, Madden BJ, Klaus KA, Morse DM, Gopala S, Nair KS. Identification of de novo synthesized and relatively older proteins: accelerated oxidative damage to de novo synthesized apolipoprotein A-1 in type 1 diabetes. Diabetes. 2010 Oct; 59(10):2366-74. Epub 2010 Jul 09. 2105078
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  35. Lanza IR, Nair KS. Mitochondrial metabolic function assessed in vivo and in vitro. Curr Opin Clin Nutr Metab Care. 2010 Sep; 13(5):511-7. 2105097
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  36. Lanza IR, Sreekumaran Nair K. Regulation of skeletal muscle mitochondrial function: genes to proteins. Acta Physiol (Oxf). 2010 Aug; 199(4):529-47. Epub 2010 Mar 25. 1992800
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  37. Hebert SL, Lanza IR, Nair KS. Mitochondrial DNA alterations and reduced mitochondrial function in aging. Mech Ageing Dev. 2010 Jul-Aug; 131(7-8):451-62. Epub 2010 Mar 20. 1992846
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  38. Henderson GC, Nadeau D, Horton ES, Nair KS. Effects of adiposity and 30 days of caloric restriction upon protein metabolism in moderately vs. severely obese women. Obesity (Silver Spring). 2010 Jun; 18(6):1135-42. Epub 2010 Feb 04. 1985076
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  39. Srinivasan M, Irving BA, Frye RL, O'Brien P, Hartman SJ, McConnell JP, Nair KS. Effects on lipoprotein particles of long-term dehydroepiandrosterone in elderly men and women and testosterone in elderly men. J Clin Endocrinol Metab. 2010 Apr; 95(4):1617-25. Epub 2010 Feb 05. 1985064
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  40. Hebert SL, Nair KS. Protein and energy metabolism in type 1 diabetes. Clin Nutr. 2010 Feb; 29(1):13-7. Epub 2009 Sep 27. 1965332
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  41. Tatpati LL, Irving BA, Tom A, Bigelow ML, Klaus K, Short KR, Nair KS. The effect of branched chain amino acids on skeletal muscle mitochondrial function in young and elderly adults. J Clin Endocrinol Metab. 2010 Feb; 95(2):894-902. Epub 2009 Dec 18. 1978297
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  42. Karakelides H, Irving BA, Short KR, O'Brien P, Nair KS. Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function. Diabetes. 2010 Jan; 59(1):89-97. Epub 2009 Oct 15. 1969706
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  43. Lanza IR, Nair KS. Mitochondrial function as a determinant of life span. Pflugers Arch. 2010 Jan; 459(2):277-89. Epub 2009 Sep 11. 1962117
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  44. Lanza IR, Zhang S, Ward LE, Karakelides H, Raftery D, Nair KS. Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes. PLoS One. 2010; 5(5):e10538. Epub 2010 May 10. 2002132
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  45. Eckel-Passow JE, Mahoney DW, Oberg AL, Zenka RM, Johnson KL, Nair KS, Kudva YC, Bergen HR III, Therneau TM. Bi-linear regression for 18O quantification: Modeling across the elution profile. Journal of Proteomics and Bioinformatics. 2010; 3(12):323-9. 2147841
  46. Short KR, Bigelow ML, Nair KS. Short-term prednisone use antagonizes insulin's anabolic effect on muscle protein and glucose metabolism in young healthy people. Am J Physiol Endocrinol Metab. 2009 Dec; 297(6):E1260-8. Epub 2009 Sep 08. 1974169
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  47. Jourdan M, Jaleel A, Karakelides H, Ford GC, Kahn BB, Nair KS. Impact of type 1 diabetes and insulin treatment on plasma levels and fractional synthesis rate of retinol-binding protein 4. J Clin Endocrinol Metab. 2009 Dec; 94(12):5125-30. Epub 2009 Oct 22. 1969645
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  48. Liu L, Shi X, Choi CS, Shulman GI, Klaus K, Nair KS, Schwartz GJ, Zhang Y, Goldberg IJ, Yu YH. Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1. Diabetes. 2009 Nov; 58(11):2516-24. Epub 2009 Aug 12. 1975832
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  49. Jaleel A, Klaus KA, Morse DM, Karakelides H, Ward LE, Irving BA, Nair KS. Differential effects of insulin deprivation and systemic insulin treatment on plasma protein synthesis in type 1 diabetic people. Am J Physiol Endocrinol Metab. 2009 Oct; 297(4):E889-97. Epub 2009 Aug 04. 1968280
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  50. Koutsari C, Ali AH, Nair KS, Rizza RA, O'Brien P, Khosla S, Jensen MD. Fatty acid metabolism in the elderly: effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women. J Clin Endocrinol Metab. 2009 Sep; 94(9):3414-23. Epub 2009 Jun 30. 1950985
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  51. Zhang S, Zheng C, Lanza IR, Nair KS, Raftery D, Vitek O. Interdependence of signal processing and analysis of urine 1H NMR spectra for metabolic profiling. Anal Chem. 2009 Aug 1; 81(15):6080-8. 1974039
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  52. Deshmukh A, Salehzadeh F, Metayer-Coustard S, Fahlman R, Nair KS, Al-Khalili L. Post-transcriptional gene silencing of ribosomal protein S6 kinase 1 restores insulin action in leucine-treated skeletal muscle. Cell Mol Life Sci. 2009 Apr; 66(8):1457-66. 1962303
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  53. Srinivasan M, Irving BA, Dhatariya K, Klaus KA, Hartman SJ, McConnell JP, Nair KS. Effect of dehydroepiandrosterone replacement on lipoprotein profile in hypoadrenal women. J Clin Endocrinol Metab. 2009 Mar; 94(3):761-4. Epub 2008 Dec 09. 1915168
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  54. Henderson GC, Dhatariya K, Ford GC, Klaus KA, Basu R, Rizza RA, Jensen MD, Khosla S, O'Brien P, Nair KS. Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements. FASEB J. 2009 Feb; 23(2):631-41. Epub 2008 Sep 30. 1915592
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  55. Lanza IR, Nair KS. Muscle mitochondrial changes with aging and exercise. Am J Clin Nutr. 2009 Jan; 89(1):467S-71S. Epub 2008 Dec 03. 1915198
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  56. Lanza IR, Nair KS. Functional assessment of isolated mitochondria in vitro. Methods Enzymol. 2009; 457:349-72. 1942143
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  57. You YN, Short KR, Jourdan M, Klaus KA, Walrand S, Nair KS. The effect of high glucocorticoid administration and food restriction on rodent skeletal muscle mitochondrial function and protein metabolism. PLoS One. 2009; 4(4):e5283. Epub 2009 Apr 20. 1937926
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  58. Allemand MC, Irving BA, Asmann YW, Klaus KA, Tatpati L, Coddington CC, Nair KS. Effect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes--a potential model for PCOS-related insulin resistance. PLoS One. 2009; 4(1):e4274. Epub 2009 Jan 26. 1920565
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  59. Lanza IR, Short DK, Short KR, Raghavakaimal S, Basu R, Joyner MJ, McConnell JP, Nair KS. Endurance exercise as a countermeasure for aging. Diabetes. 2008 Nov; 57(11):2933-42. Epub 2008 Aug 20. 1906855
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  60. Dhatariya KK, Greenlund LJ, Bigelow ML, Thapa P, Oberg AL, Ford GC, Schimke JM, Nair KS. Dehydroepiandrosterone replacement therapy in hypoadrenal women: protein anabolism and skeletal muscle function. Mayo Clin Proc. 2008 Nov; 83(11):1218-25. 1915421
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  61. Jaleel A, Short KR, Asmann YW, Klaus KA, Morse DM, Ford GC, Nair KS. In vivo measurement of synthesis rate of individual skeletal muscle mitochondrial proteins. Am J Physiol Endocrinol Metab. 2008 Nov; 295(5):E1255-68. Epub 2008 Sep 02. 1915703
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  62. Greenlund LJ, Nair KS, Brennan MD. Changes in body composition in women following treatment of overt and subclinical hyperthyroidism. Endocr Pract. 2008 Nov; 14(8):973-8. 1817214
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  63. Singh M, Alexander K, Roger VL, Rihal CS, Whitson HE, Lerman A, Jahangir A, Nair KS. Frailty and its potential relevance to cardiovascular care. Mayo Clin Proc. 2008 Oct; 83(10):1146-53. 1904602
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  64. Walrand S, Short KR, Bigelow ML, Sweatt AJ, Hutson SM, Nair KS. Functional impact of high protein intake on healthy elderly people. Am J Physiol Endocrinol Metab. 2008 Oct; 295(4):E921-8. Epub 2008 Aug 12. 1909250
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  65. Giannoulis MG, Jackson N, Shojaee-Moradie F, Nair KS, Sonksen PH, Martin FC, Umpleby AM. The effects of growth hormone and/or testosterone on whole body protein kinetics and skeletal muscle gene expression in healthy elderly men: a randomized controlled trial. J Clin Endocrinol Metab. 2008 Aug; 93(8):3066-74. Epub 2008 May 13. 1949956
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  66. Rossetti P, Porcellati F, Busciantella Ricci N, Candeloro P, Cioli P, Nair KS, Santeusanio F, Bolli GB, Fanelli CG. Effect of oral amino acids on counterregulatory responses and cognitive function during insulin-induced hypoglycemia in nondiabetic and type 1 diabetic people. Diabetes. 2008 Jul; 57(7):1905-17. Epub 2008 Apr 04. 1909760
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  67. Bhagra S, Nippoldt TB, Nair KS. Dehydroepiandrosterone in adrenal insufficiency and ageing. Curr Opin Endocrinol Diabetes Obes. 2008 Jun; 15(3):239-43. 1891532
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  68. Nair KS, Bigelow ML, Asmann YW, Chow LS, Coenen-Schimke JM, Klaus KA, Guo ZK, Sreekumar R, Irving BA. Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance. Diabetes. 2008 May; 57(5):1166-75. Epub 2008 Feb 19. 1892639
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  69. Igwebuike A, Irving BA, Bigelow ML, Short KR, McConnell JP, Nair KS. Lack of dehydroepiandrosterone effect on a combined endurance and resistance exercise program in postmenopausal women. J Clin Endocrinol Metab. 2008 Feb; 93(2):534-8. Epub 2007 Nov 20. 1872064
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  70. Short KR, Moller N, Bigelow ML, Coenen-Schimke J, Nair KS. Enhancement of muscle mitochondrial function by growth hormone. J Clin Endocrinol Metab. 2008 Feb; 93(2):597-604. Epub 2007 Nov 13. 1872065
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  71. Moller N, Nair KS. Diabetes and protein metabolism. Diabetes. 2008 Jan; 57(1):3-4. 1888463
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  72. Karakelides H, Asmann YW, Bigelow ML, Short KR, Dhatariya K, Coenen-Schimke J, Kahl J, Mukhopadhyay D, Nair KS. Effect of insulin deprivation on muscle mitochondrial ATP production and gene transcript levels in type 1 diabetic subjects. Diabetes. 2007 Nov; 56(11):2683-9. Epub 2007 Jul 27. 1848972
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  73. Basu R, Dalla Man C, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA. Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men. Diabetes Care. 2007 Aug; 30(8):1972-8. Epub 2007 May 11. 1841643
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  74. Irving BA, Nair KS. Aging and diabetes: mitochondrial dysfunction. Curr Diab Rep. 2007 Aug; 7(4):249-51. 1839131
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  75. Sreekumar R, Nair KS. Skeletal muscle mitochondrial dysfunction & diabetes. Indian J Med Res. 2007 Mar; 125(3):399-410. 2317725
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  76. Basu R, Dalla Man C, Campioni M, Basu A, Nair KS, Jensen MD, Khosla S, Klee G, Toffolo G, Cobelli C, Rizza RA. Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women. Diabetes. 2007 Mar; 56(3):753-66. 2210950
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  77. Chow LS, Greenlund LJ, Asmann YW, Short KR, McCrady SK, Levine JA, Nair KS. Impact of endurance training on murine spontaneous activity, muscle mitochondrial DNA abundance, gene transcripts, and function. J Appl Physiol. 2007 Mar; 102(3):1078-89. 1812297
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  78. Moller N, Copeland KC, Nair KS. Growth hormone effects on protein metabolism. Endocrinol Metab Clin North Am. 2007 Mar; 36(1):89-100. 1817563
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  79. Short KR, Nygren J, Nair KS. Effect of T(3)-induced hyperthyroidism on mitochondrial and cytoplasmic protein synthesis rates in oxidative and glycolytic tissues in rats. Am J Physiol Endocrinol Metab. 2007 Feb; 292(2):E642-7. 1807180
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  80. Mason CJ, Therneau TM, Eckel-Passow JE, Johnson KL, Oberg AL, Olson JE, Nair KS, Muddiman DC, Bergen HR 3rd. A method for automatically interpreting mass spectra of 18O-labeled isotopic clusters. Mol Cell Proteomics. 2007 Feb; 6(2):305-18. 1810457
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  81. Asmann YW, Stump CS, Short KR, Coenen-Schimke JM, Guo Z, Bigelow ML, Nair KS. Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia. Diabetes. 2006 Dec; 55(12):3309-19. 1794596
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  82. Brennan MD, Coenen-Schimke JM, Bigelow ML, Nair KS. Changes in skeletal muscle protein metabolism and myosin heavy chain isoform messenger ribonucleic acid abundance after treatment of hyperthyroidism. J Clin Endocrinol Metab. 2006 Nov; 91(11):4650-6. Epub 2006 Aug 29. 1791325
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  83. Nair KS, Rizza RA, O'Brien P, Dhatariya K, Short KR, Nehra A, Vittone JL, Klee GG, Basu A, Basu R, Cobelli C, Toffolo G, Dalla Man C, Tindall DJ, Melton LJ 3rd, Smith GE, Khosla S, Jensen MD. DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med. 2006 Oct 19; 355(16):1647-59. 1787068
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  84. Chow LS, Albright RC, Bigelow ML, Toffolo G, Cobelli C, Nair KS. Mechanism of insulin's anabolic effect on muscle: measurements of muscle protein synthesis and breakdown using aminoacyl-tRNA and other surrogate measures. Am J Physiol Endocrinol Metab. 2006 Oct; 291(4):E729-36. Epub 2006 May 16. 1786869
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  85. Abu-Lebdeh HS, Barazzoni R, Meek SE, Bigelow ML, Persson XM, Nair KS. Effects of insulin deprivation and treatment on homocysteine metabolism in people with type 1 diabetes. J Clin Endocrinol Metab. 2006 Sep; 91(9):3344-8. Epub 2006 Jun 13. 1782337
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  86. Moller N, Jensen MD, Rizza RA, Andrews JC, Nair KS. Renal amino acid, fat and glucose metabolism in type 1 diabetic and non-diabetic humans: effects of acute insulin withdrawal. Diabetologia. 2006 Aug; 49(8):1901-8. Epub 2006 May 23. 1770161
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  87. Jaleel A, Nehra V, Persson XM, Boirie Y, Bigelow M, Nair KS. In vivo measurement of synthesis rate of multiple plasma proteins in humans. Am J Physiol Endocrinol Metab. 2006 Jul; 291(1):E190-7. Epub 2006 Jan 31. 1769928
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  88. Ostergard T, Andersen JL, Nyholm B, Lund S, Nair KS, Saltin B, Schmitz O. Impact of exercise training on insulin sensitivity, physical fitness, and muscle oxidative capacity in first-degree relatives of type 2 diabetic patients. Am J Physiol Endocrinol Metab. 2006 May; 290(5):E998-1005. Epub 2005 Dec 13. 1760784
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  89. Brennan MD, Powell C, Kaufman KR, Sun PC, Bahn RS, Nair KS. The impact of overt and subclinical hyperthyroidism on skeletal muscle. Thyroid. 2006 Apr; 16(4):375-80. 1762756
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  90. Freyse EJ, Fischer U, Knospe S, Ford GC, Nair KS. Differences in protein and energy metabolism following portal versus systemic administration of insulin in diabetic dogs. Diabetologia. 2006 Mar; 49(3):543-51. Epub 2006 Jan 31. 1750494
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  91. Tom A, Nair KS. Assessment of branched-chain amino Acid status and potential for biomarkers. J Nutr. 2006 Jan; 136(1 Suppl):324S-30S. 1744150
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  92. Morgenstern BZ, Wuhl E, Nair KS, Warady BA, Schaefer F. Anthropometric prediction of total body water in children who are on pediatric peritoneal dialysis. J Am Soc Nephrol. 2006 Jan; 17(1):285-93. Epub 2005 Nov 30. 1792868
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  93. Di Camillo B, Sanchez-Cabo F, Toffolo G, Nair SK, Trajanoski Z, Cobelli C. A quantization method based on threshold optimization for microarray short time series. BMC Bioinformatics. 2005 Dec 01; 6 Suppl 4:S11. 1971793
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  94. Chow LS, Nair KS. Sarcopenia of male aging. Endocrinology & Metabolism Clinics of North America. 2005 Dec; 34(4):833-52. 1743608
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  95. Short KR, Vittone JL, Bigelow ML, Proctor DN, Coenen-Schimke JM, Rys P, Nair KS. Changes in myosin heavy chain mRNA and protein expression in human skeletal muscle with age and endurance exercise training. Journal of Applied Physiology. 2005 Jul; 99(1):95-102. 1721470
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  96. Riis ALD, Jorgensen JOL, Gjedde S, Norrelund H, Jurik AG, Nair KS, Ivarsen P, Weeke J, Moller N. Whole body and forearm substrate metabolism in hyperthyroidism: evidence of increased basal muscle protein breakdown. Am J Physiol Endocrinol Metab. 2005 Jun; 288(6):E1067-73. 1720398
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  97. Nair KS, Short KR. Hormonal and signaling role of branched-chain amino acids. J Nutr. 2005 Jun; 135(6 Suppl):1547S-52S. 1718780
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  98. Nair KS. Aging muscle. Am J Clin Nutr. 2005 May; 81(5):953-63. 1714673
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  99. Short KR, Bigelow ML, Kahl J, Singh R, Coenen-Schimke J, Raghavakaimal S, Nair KS. Decline in skeletal muscle mitochondrial function with aging in humans. Proc Natl Acad Sci U S A. 2005 Apr 12; 102(15):5618-23. Epub 2005 Mar 30. 1708063
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  100. Jaleel A, Halvatsiotis P, Williamson B, Juhasz P, Martin S, Nair KS. Identification of Amadori-modified plasma proteins in type 2 diabetes and the effect of short-term intensive insulin treatment. Diabetes Care. 2005 Mar; 28(3):645-52. 1701739
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  101. Dhatariya K, Bigelow ML, Nair KS. Effect of dehydroepiandrosterone replacement on insulin sensitivity and lipids in hypoadrenal women. Diabetes. 2005 Mar; 54(3):765-9. 1701667
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  102. Nair KS. Amino acid and protein metabolism in chronic renal failure. J Ren Nutr. 2005 Jan; 15(1):28-33. 1694164
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  103. Karakelides H, Nair KS. Sarcopenia of aging and its metabolic impact. Curr Top Dev Biol. 2005; 68:123-48. 1726763
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  104. Short KR, Nygren J, Bigelow ML, Nair KS. Effect of short-term prednisone use on blood flow, muscle protein metabolism, and function. J Clin Endocrinol Metab. 2004 Dec; 89(12):6198-207. 1674514
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  111. Norrelund H, Djurhuus C, Jorgensen JOL, Nielsen S, Nair KS, Schmitz O, Christiansen JS, Moller N. Effects of GH on urea, glucose and lipid metabolism, and insulin sensitivity during fasting in GH-deficient patients. American Journal of Physiology - Endocrinology & Metabolism. 2003 Oct 1; 285(4):E737-43. 1413668
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  112. Dhatariya KK, Nair KS. Dehydroepiandrosterone: Is there a role for replacement? Mayo Clin Proc. 2003 Oct; 78(10):1257-73. 1416942
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  115. Stump CS, Short KR, Bigelow ML, Schimke JM, Nair KS. Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7996-8001. Epub 2003 Jun 13. 1404300
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  116. Nygren J, Nair KS. Differential regulation of protein dynamics in splanchnic and skeletal muscle beds by insulin and amino acids in healthy human subjects. Diabetes. 2003 Jun; 52(6):1377-85. 1355755
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  117. Greenlund LJS, Nair KS. Sarcopenia-consequences, mechanisms; and potential therapies. Mech Ageing Dev. 2003 Mar; 124(3):287-99. 1341045
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  118. Moller N, Nygren J, Hansen TK, Orskov H, Frystyk J, Nair KS. Splanchnic release of ghrelin in humans. J Clin Endocrinol Metab. 2003 Feb; 88(2):850-2. 1318559
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  119. Shah P, Vella A, Basu A, Basu R, Adkins A, Schwenk WF, Johnson CM, Nair KS, Jensen MD, Rizza RA. Elevated free fatty acids impair glucose metabolism in women: decreased stimulation of muscle glucose uptake and suppression of splanchnic glucose production during combined hyperinsulinemia and hyperglycemia. Diabetes. 2003 Jan; 52(1):38-42. 1317988
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  120. Levine JA, Nygren J, Short KR, Nair KS. Effect of hyperthyroidism on spontaneous physical activity and energy expenditure in rats. J Appl Physiol. 2003 Jan; 94(1):165-70. 1317923
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  122. Halvatsiotis P, Short KR, Bigelow M, Nair KS. Synthesis rate of muscle proteins, muscle functions, and amino acid kinetics in type 2 diabetes. Diabetes. 2002 Aug; 51(8):2395-404. 1314962
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  123. Sreekumar R, Unnikrishnan J, Fu A, Nygren J, Short KR, Schimke J, Barazzoni R, Nair KS. Effects of caloric restriction on mitochondrial function and gene transcripts in rat muscle. American Journal of Physiology - Endocrinology & Metabolism. 2002 Jul; 283(1):E38-E43. 1315929
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  126. Caso G, Ford GC, Nair KS, Garlick PJ, McNurlan MA. Aminoacyl-tRNA enrichment after a flood of labeled phenylalanine: insulin effect on muscle protein synthesis. American Journal of Physiology - Endocrinology & Metabolism. 2002 May; 282(5):E1029-E1038. 1315350
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  127. Sreekumar R, Unnikrishnan J, Fu A, Nygren J, Short KR, Schimke J, Barazzoni R, Nair KS. Impact of high-fat diet and antioxidant supplement on mitochondrial functions and gene transcripts in rat muscle. American Journal of Physiology - Endocrinology & Metabolism. 2002 May; 282(5):E1055-E1061. 1315351
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  128. Sato J, O'Brien T, Katusic ZS, Fu AZ, Nygren J, Singh R, Nair KS. Dietary antioxidants preserve endothelium dependent vasorelaxation in overfed rats. Atherosclerosis. 2002 Apr; 161(2):327-33. 1315343
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  129. Charlton N, Sreekumar R, Rasmussen D, Lindor K, Nair KS. Apolipoprotein synthesis in nonalcoholic steatohepatitis. Hepatology. 2002 Apr; 35(4):898-904. 1315389
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  130. Shah P, Vella A, Basu A, Basu R, Adkins A, Schwenk WF, Johnson CM, Nair KS, Jensen MD, Rizza RA. Effects of free fatty acids and glycerol on splanchnic glucose metabolism and insulin extraction in nondiabetic humans. Diabetes. 2002 Feb; 51(2):301-10. 1008071
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  131. Basu R, Basu A, Nair KS. Muscle changes in aging. J Nutr Health Aging. 2002; 6(5):336-41. 1652514
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  133. Boirie Y, Short KR, Ahlman B, Charlton M, Nair KS. Tissue-specific regulation of mitochondrial and cytoplasmic protein synthesis rates by insulin. Diabetes. 2001 Dec; 50(12):2652-8. 1014778
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  134. Norrelund H, Moller N, Nair KS, Christiansen JS, Jorgensen JO. Continuation of growth hormone (GH) substitution during fasting in GH-deficient patients decreases urea excretion and conserves protein synthesis. J Clin Endocrinol Metab. 2001 Jul; 86(7):3120-9. 1005606
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  135. Short KR, Nair KS. Does aging adversely affect muscle mitochondrial function? Exerc Sport Sci Rev. 2001 Jul; 29(3):118-23. 1007280
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  136. Caso G, Ford GC, Nair KS, Vosswinkel JA, Garlick PJ, McNurlan MA. Increased concentration of tracee affects estimates of muscle protein synthesis. Am J Physiol Endocrinol Metab. 2001 Jun; 280(6):E937-46. 1005025
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  137. Moran A, Milla C, Ducret R, Nair KS. Protein metabolism in clinically stable adult cystic fibrosis patients with abnormal glucose tolerance. Diabetes. 2001 Jun; 50(6):1336-43. 1005093
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  138. Basu A, Basu R, Shah P, Vella A, Johnson CM, Jensen M, Nair KS, Schwenk WF, Rizza RA. Type 2 diabetes impairs splanchnic uptake of glucose but does not alter intestinal glucose absorption during enteral glucose feeding: additional evidence for a defect in hepatic glucokinase activity. Diabetes. 2001 Jun; 50(6):1351-62. 1005094
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  139. Short KR, Nygren J, Barazzoni R, Levine J, Nair KS. T(3) increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP2 and -3. Am J Physiol Endocrinol Metab. 2001 May; 280(5):E761-9. 1005057
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  140. Ahlman B, Charlton M, Fu A, Berg C, O'Brien P, Nair KS. Insulin's effect on synthesis rates of liver proteins. A swine model comparing various precursors of protein synthesis. Diabetes. 2001 May; 50(5):947-54. 1004556
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  142. Morley JE, Baumgartner RN, Roubenoff R, Mayer J, Nair KS. Sarcopenia. Journal of Laboratory & Clinical Medicine. 2001 Apr; 137(4):231-43. 1003941
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  143. Barazzoni R, Nair KS. Changes in uncoupling protein-2 and -3 expression in aging rat skeletal muscle, liver, and heart. Am J Physiol Endocrinol Metab. 2001 Mar; 280(3):E413-9. 1003710
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  145. Norrelund H, Nair KS, Jorgensen JO, Christiansen JS, Moller N. The protein-retaining effects of growth hormone during fasting involve inhibition of muscle-protein breakdown. Diabetes. 2001 Jan; 50(1):96-104. 1003534
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  146. Balagopal P Schimke JMC, Ades P Adey D, Nair KS. Age effect on gene expression of myosin heavy chain (MHC) isoforms and the effect of resistance effect on gene expression and synthesis of MHC. Am J Physiol. 2001; 280:E203-8. 152229
  147. Short KR, Nygren J, Barazzoni R, Levine J, Nair KS. T3 increases mitochondrial ATP production in oxidative but not glycolytic muscle despite increased expression of UCP -2 and -3. Am J Physiol. 2001; 280:E761--E769. 1139798
  148. Morgenstern B, Nair KS, Lerner G, Neu A, Quan A, Warady BA, Pediatric Peritoneal Dialysis Study Consortium. Impact of total body water errors on Kt/V estimates in children on peritoneal dialysis. Adv Perit Dial. 2001; 17:260-3. 1979987
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  149. Lee JS, Camilleri M, Zinsmeister AR, Burton DD, Choi MG, Nair KS, Verlinden M. Toward office-based measurement of gastric emptying in symptomatic diabetics using [13C]octanoic acid breath test. Am J Gastroenterol. 2000 Oct; 95(10):2751-61. 139479
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  150. Sato J, Nair K, Hiddinga J, Eberhardt NL, Fitzpatrick LA, Katusic ZS, O'Brien T. eNOS gene transfer to vascular smooth muscle cells inhibits cell proliferation via upregulation of p27 and p21 and not apoptosis. Cardiovasc Res. 2000 Sep; 47(4):697-706. 137457
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  151. Sato J, Singh RJ, I'Brien T, Katusic ZS, Fu A, Nygren JA, Nair KS. Dietary antioxidants preserve endothelium dependent vasorelaxation in obese rats. Clin Chem Part 2, Suppl S. 2000 Jun; 46(6):398. 1241249
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  153. Norrelund H, Borglum J, Jorgensen JOL, Richelsen B, Moller N, Nair KS, Christiansen JS. Effects of growth hormone administration on protein dynamics and substrate metabolism during four weeks of dietary restriction in obese women. Clin Endocrinol (Oxf) 2000 Mar; 52(3):305-312. 1012776
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  154. Barazzoni R, Short KR, Nair KS. Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart. J Biol Chem. 2000 Feb 4; 275(5):3343-7. 128311
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  155. Moller N, Meek S, Bigelow M, Andrews J, Nair KS. The kidney is an important site for in vivo phenylalanine-to-tyrosine conversion in adult humans: A metabolic role of the kidney. Proc Natl Acad Sci U S A. 2000 Feb 1; 97(3):1242-6. 128283
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  156. Basu A, Basu R, Shah P, Vella A, Johnson CM, Nair KS, Jensen MD, Schwenk WF, Rizza RA. Effects of type 2 diabetes on the ability of insulin and glucose to regulate splanchnic and muscle glucose metabolism: evidence for a defect in hepatic glucokinase activity. Diabetes. 2000 Feb; 49(2):272-83. 128316
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  157. Adey D, Kumar R, McCarthy JT, Nair KS. Reduced synthesis of muscle proteins in chronic renal failure. American Journal of Physiology - Endocrinology & Metabolism. 2000 Feb; 278(2):E219-25. 128489
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  158. Charlton M, Ahlman B, Nair KS. The effect of insulin on human small intestinal mucosal protein synthesis. Gastroenterology. 2000 Feb; 118(2):299-306. 127574
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  159. Short KR, Nair KS. The effect of age on protein metabolism. Current Opinion in Clinical Nutrition & Metabolic Care. 2000 Jan; 3(1):39-44. 130326
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  160. Nair KS. Age-related changes in muscle. Mayo Clin Proc. 2000 Jan; 75 Suppl:S14-8. 1013298
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  162. Dumesic DA, Nielsen MF, Abbott DH, Eisner JR, Nair KS, Rizza RA. Insulin action during variable hyperglycemic-hyperinsulinemic infusions in hyperandrogenic anovulatory patients and healthy women. Fertil Steril. 1999 Sep; 72(3):458-66. 1009046
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  163. Proctor DN, O'Brien PC, Atkinson EJ, Nair KS. Comparison of techniques to estimate total body skeletal muscle mass in people of different age groups. Am J Physiol. 1999 Sep; 277(3 Pt 1):E489-95. 1009954
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  164. Barazzoni R, Meek SE, Ekberg K, Wahren J, Nair KS. Arterial KIC as marker of liver and muscle intracellular leucine pools in healthy and type 1 diabetic humans. Am J Physiol. 1999 Aug; 277(2 Pt 1):E238-44. 1009033
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  165. Wahren JP6, Ekberg K, Fernqvist-Forbes E, Nair S. Brain substrate utilisation during acute hypoglycaemia. Diabetologia. 1999 Jul; 42(7):812-8. 1316516
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  166. Coenen Schimke JM, Ljungqvist OH, Sarkar G, Conover CA, Nair KS. A quantitative PCR measurement of messenger RNA expression of IGF-I, IGF-II and IGFBP-5 in human skeletal muscle. Growth Horm IGF Res. 1999 Jun; 9(3):179-86. 2121259
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  167. Short KR, Meek SE, Moller N, Ekberg K, Nair KS. Whole body protein kinetics using Phe and Tyr tracers: an evaluation of the accuracy of approximated flux values. Am J Physiol. 1999 Jun; 276(6 Pt 1):E1194-200. 117170
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  168. Thorell A, Nygren J, Hirshman MF, Hayashi T, Nair KS, Horton ES, Goodyear LJ, Ljungqvist O. Surgery-induced insulin resistance in human patients: relation to glucose transport and utilization. Am J Physiol. 1999 Apr; 276(4 Pt 1):E754-61. 112616
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  169. Meek SE, Nair KS, Jensen MD. Insulin regulation of regional free fatty acid metabolism. Diabetes. 1999 Jan; 48(1):10-4. 109064
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  170. Jensen MD, Moller N, Nair KS, Eisenberg P, Landt M, Klein S. Regional leptin kinetics in humans. Am J Clin Nutr. 1999 Jan; 69(1):18-21. 109141
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  171. Short KR, Nair KS. Mechanisms of sarcopenia of aging. J Endocrinol Invest. 1999; 22(5 Suppl):95-105. 123594
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  172. Thorell A, Nygren J, Hirshman M, Goodyear L, Horton ES, Nair KS, O Ljungqvist. Glucose kinetics muscle glucose tranporter GLUT4 and glucose metabolism during elective surgery during hyperinsulinemia. Am J Physiol. 1999; 277:E733-41. 1139776
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  173. Nygren J, Soop M, Thorell A, Nair KS, Ljungqvist O. Preoperative oral carbohydrates and postoperative insulin resistance. Clin Nutr. 1999; 18(2):117-20. 1139782
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  174. Meek SE, Persson M, Ford GC, Nair KS. Differential regulation of amino acid exchange and protein dynamics across splanchnic and skeletal muscle beds by insulin in healthy human subjects. Diabetes. 1998 Dec; 47(12):1824-35. 108575
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  175. Fu A, Sreekumaran Nair K. Age effect on fibrinogen and albumin synthesis in humans. Am J Physiol. 1998 Dec; 275(6 Pt 1):E1023-30. 1019295
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  176. Charlton MR, Nair KS. Role of hyperglucagonemia in catabolism associated with type 1 diabetes: effects on leucine metabolism and the resting metabolic rate. Diabetes. 1998 Nov; 47(11):1748-56. 108219
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  177. Nippoldt TB, Nair KS. Is there a case for DHEA replacement? Bailliere's Clinical Endocrinology and Metabolism. 1998 Oct; 12(3):507-20. 110846
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  178. Nygren JO, Thorell A, Soop M, Efendic S, Brismar K, Karpe F, Nair KS, Ljungqvist O. Perioperative insulin and glucose infusion maintains normal insulin sensitivity after surgery. Am J Physiol Endocrinol Metab. 1998 Jul; 275(1):E 140-E 148. 106553
  179. Elharake WA, Furman MA, Cook B, Nair KS, Kukowski J, Brodsky IG. Measurement of dermal collagen synthesis rate in vivo in humans. Am J Physiol Endocrinol Metab. 1998 Apr; 274(4):E 586-E 591. 104731
  180. Moller N, O'Brien P, Nair KS. Disruption of the relationship between fat content and leptin levels with aging in humans. J Clin Endocrinol Metab. 1998 Mar; 83(3):931-4. 103921
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  181. Charlton M, Nair KS. Protein metabolism in insulin-dependent diabetes mellitus. J Nutr. 1998 Feb; 128(2 Suppl):323S-327S. 103436
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  182. Proctor DN, Balagopal P, Nair KS. Age-related sarcopenia in humans is associated with reduced synthetic rates of specific muscle proteins. J Nutr. 1998 Feb; 128(2 Suppl S):S 351-S 355. 103437
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  183. Choi MG, Camilleri M, Burton DD, Zinsmeister AR, Forstrom LA, Nair KS. Reproducibility and simplification of 13C-octanoic acid breath test for gastric emptying of solids. Am J Gastroenterol. 1998 Jan; 93(1):92-8. 103892
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  184. Thorell A, Nygren J, Hirshman M, Goodyear L, Horton ES, Nair KS, Ljungqvist O. Preoperative oral carbohydrate administration reduces postoperative insulin resistance. Clin Nutr. 1998; 17:64-71. 152218
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  185. Charlton M, Nair KS. Protein metabolism in type-1 diabetes J Nutrition. 1998; 128:323S-7S. 151954
  186. Vogiatzi MG, Nair KS, Beckett PR, Copeland KC. Insulin does not stimulate protein synthesis acutely in prepubertal children with insulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1997 Dec; 82(12):4083-7. 101115
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  187. Balagopal P, Rooyackers OE, Adey DB, Ades PA, Nair KS. Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans. Am J Physiol Endocrinol Metab. 1997 Oct; 273(4):E 790-E 800. 100424
  188. Ljungqvist OH, Persson M, Ford GC, Nair KS. Functional heterogeneity of leucine pools in human skeletal muscle. Am J Physiol Endocrinol Metab. 1997 Sep; 273(3):E 564-E 570. 99791
  189. Nygren J, Thorell A, Efendic S, Nair KS, Ljungqvist O. Site of insulin resistance after surgery: the contribution of hypocaloric nutrition and bed rest. Clin Sci (Lond) 1997 Aug; 93(2):137-46. 99257
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  190. Balagopal P, Proctor D, Nair KS. Sarcopenia and hormonal changes. Endocrine. 1997 Aug; 7(1):57-60. 101062
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  191. Charlton MR, Balagopal P, Nair KS. Skeletal muscle myosin heavy chain synthesis in type 1 diabetes. Diabetes. 1997 Aug; 46(8):1336-40. 1314330
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  192. Fu AZ, Morris JC, Ford GC, Nair KS. Sequential purification of human apolipoprotein B-100, albumin, and fibrinogen by immunoaffinity chromatography for measurement of protein synthesis. Anal Biochem. 1997 May 1; 247(2):228-36. 102494
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  193. Choi MG, Camilleri M, Burton DD, Zinsmeister AR, Forstrom LA, Nair KS. [13C]octanoic acid breath test for gastric emptying of solids: accuracy, reproducibility, and comparison with scintigraphy. Gastroenterology. 1997 Apr; 112(4):1155-62. 102149
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  194. Balagopal P, Ljungqvist O, Nair KS. Skeletal muscle myosin heavy-chain synthesis rate in healthy humans. Am J Physiol Endocrinol Metab. 1997 Jan; 272(1):E 45-E 50. 101716
  195. Rooyackers OE, Nair KS. Hormonal regulation of human muscle protein metabolism. Annu Rev Nutr. 1997; 17:457-85. 99263
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  196. Rooyackers OE, Balagopal P, Nair KS. Measurement of synthesis rates of specific muscle proteins using needle biopsy samples. Muscle Nerve. 1997; 20(Suppl 5):S 93-S 96. 100194
  197. Bernstein IM, Silver R, Nair KS, Stirewalt W. Amniotic fluid glycine-valine ratio and neonatal morbidity in fetal growth restriction. Obstetrics and Gynecology. 1997; 90:933-7. 1139774
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  198. Rooyackers OE, Adey DB, Ades PA, Nair KS. Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle. Proc Natl Acad Sci U S A. 1996 Dec 24; 93(26):15364-9. 98406
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  199. Brodsky IG, Balagopal P, Nair KS. Effects of testosterone replacement on muscle mass and muscle protein synthesis in hypogonadal men--a clinical research center study. J Clin Endocrinol Metab. 1996 Oct; 81(10):3469-75. 97873
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  200. Abu-Lebdeh HS, Nair KS. Protein metabolism in diabetes mellitus. Baillieres Clin Endocrinol Metab. 1996 Oct; 10(4):589-601. 98432
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  201. Balagopal P, Ford GC, Ebenstein DB, Nadeau DA, Nair KS. Mass spectrometric methods for determination of [13C]Leucine enrichment in human muscle protein. Anal Biochem. 1996 Jul 15; 239(1):77-85. 97139
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  202. Charlton MR, Adey DB, Nair KS. Evidence for a catabolic role of glucagon during an amino acid load. J Clin Invest. 1996 Jul 1; 98(1):90-9. 96676
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  203. Coenen Schminke J, Ljungqvist O, Sarkar G, Conover CA, Nair KS. mRNA levels of insulin-like growth factor I and II and binding proteins 4 and 5 in human skeletal muscle. Biomedicine '96 Washington, DC, 1996 May. 1139909
  204. Ades PA, Ballor DL, Ashikaga T, Utton JL, Nair KS. Weight training improves walking endurance in healthy elderly persons. Ann Intern Med. 1996 Mar 15; 124(6):568-72. 95242
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  205. Calles-Escandon J, Gorna MI, O'Connell M, Nair KS, Danforth E Jr. Exercise increases fat oxidation at rest unrelated to changes in energy balance or lipolysis. Am J Physiol. 1996; 270:E1009-14. 152215
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  206. Vittone J, Ballor D, Nair KS. Muscle wasting in the elderly Age and Nutrition. 1996; 7:96-105. 145283
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  209. Nair KS, Adey D, Charlton M, Ljungqvist O. Protein metabolism in diabetes mellitus. Diabetes Nutr Metab. 1995 Apr; 8:113-122. 92576
  210. Turk D, Alzaid A, Dinneen S, Nair KS, Rizza R. The effects of non-insulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues. J Clin Invest. 1995 Feb; 95(2):755-62. 91896
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  211. Nadeau DA, Nair KS, Rosen C, Copeland KC. Effect of Octreotide on growth hormone-induced insulin-like growth factor-I production in humans. Endocrinology and Metabolism. 1995; 1:181-5. 152213
  212. Nair KS, Schwenk WF. Factors controlling muscle protein synthesis and degradation. Curr Opin Neurol. 1994 Oct; 7(5):471-4. 88894
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  213. Balagopal P, Nair KS, Stirewalt WS. Isolation of myosin heavy chain from small skeletal muscle samples by preparative continuous elution gel electrophoresis: application to measurement of synthesis rate in human and animal tissue. Anal Biochem. 1994 Aug 15; 221(1):72-7. 89028
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  214. Baumann PQ, Stirewalt WS, Orourke BD, Howard D, Nair KS. Precursor pools of protein synthesis--a stable isotope study in a swine model. Am J Physiol. 1994 Aug; 267:E203-E209. 88586
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  215. Copeland KC, Nair KS. Acute growth hromone effects on amino acid and lipid metabolism. J Clin Endocrinol Metab. 1994; 78:1040-7. 152204
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  216. Nair KS, Pabico R, Mckenna B, Truglia J, Lockwood D. Mechanism of glomerular hyperfilteration after protein use. Diabetes Care. 1994; 17:711-7115. 152205
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  217. Copeland KC, Nair KS. Recombinant human insulin-like growth factor increases forearm blood flow. J Clin Endo Metab. 1994; 79:230-2. 152207
  218. Goran MI, Pehlman ET, Danfort E Jr, Nair KS. Comparison of body fat estimates derived from underwater weight and total body water. Int J Obesity. 1994; 18:622-66. 152208
  219. Speakman J, Nair KS, Goran MI. Revised equation for calculating double labelled water in humans. Am J Physiol. 1993; 264:E912-7. 152199
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  220. Copeland KC, Nair KS, Calles-Escandon J. Discordant metabolic actions of insulin in extreme lipodystrophy of childhood J Clin Endocrinol and Metab. 1993; 77:1240-5. 152200
  221. Byerley LO, Lee WNP, Swerdloff RS, Buena Fl, Nair KS, Buchanan TA, Goldberg RB, Steiner B, Bhasin S. Effect of modulating serum testosterone levels in the normal male range on protein, glucose and lipid metabolism in men: implications for testosterone replacement therapy. Endocrine J. 1993; 1:253-62. 152202
  222. Goran MI, Poehlman ET, Nair KS, Danforth E Jr. Deuterium exchange in humans: effect of gender, body composition and age. Basic Life Sciences. 1993; 60:79-81. 152203
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  223. Nair KS, Matthew DE, Welle SL, Braiman T. Effect of leucine on amino acid and glucose metabolism in humans. Metabolism. 1992; 41:643-8. 152193
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  224. Baumann PQ, Ebenstein D, O'Rourke B, Nair KS. High performance liquid chromotographic technique for non-derivatized leucine purification: evidence for carbon isotope fractionation. J Chromatography. 1992; 573:11-6. 152194
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  228. Nair KS, Welle SL, Tito J. Effect of plasma amino acids replacement on glucagon response to hypoglycemia and substrate metabolism. Diabetes. 1990; 39:376-82. 152187
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  229. Griggs RC, Jozefowicz R, Kingston W, Nair KS, Herr BE, Halliday D. Mechanisms of muscle wasting in myotonic dystrophy. Annals of Neurology. 1990; 27:505-12. 152189
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  231. Welle SL, Nair KS. Effect of insulin and glyburide treatment on protein metabolism in type II diabetes mellitus. Int J Obesity. 1990; 16:701-10. 152191
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  234. Welle S, Nair KS, Campbell RG. Failure of chronic beta adrenergic blockade to inhibit overfeeding-induced thermogenesis in man. Am J Physiol. 1989; 256:R653-8. 152184
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  235. Welle S, Matthews DE, Campbell RG, Nair KS. Stimulation of protein turnover by carbohydrate overfeeding in man. Am J Physiol. 1989; 257:E413-7. 152186
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  236. Welle SL, Nair KS, Lockwood D. Effect of a sulfonylurea and insulin on energy expenditure in type II diabetes mellitus. J Clin Endocrinol Metab. 1988; 66:593-7. 1139772
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  237. Nair KS, Welle SL, Halliday D, Campbell RG. Effect of beta-hydroxybutyrate on whole body leucine kinetics and fractoinal mixed skeletal muscle protein synthesis in man. J Clin Invest. 1988; 82:198-205. 152178
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  238. Nair KS, Halliday D, Griggs RC. Leucine incorporation into mixed skeletal muscle protein in humans. Am J Physiol. 1988; 254:E208-13. 152179
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  239. Nair KS, Ford GC, Halliday D. Effect of intravenous insulin treatment on in vivo whole body leucine kinetics and oxygen consumption in insulin-deprived type I diabetic patients Metabolism. 1987; 36:491-5. 151966
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  240. Nair KS. Hyperglucagonemia increases resting metabolic rate in man during insulin deficiency J Clin Endocrinol Metab. 1987; 64:896-901. 151967
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  241. Nair KS, Halliday D, Matthews DE, Welle SL. Hyperglucagonemia during insulin deficiency accelerates protein catabolism. Am J Physiol. 1987; 253:E208-13. 152174
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  242. Nair KS, Halliday D, Ford GC, Heels S, Garrow JS. Failure of carbohydrate to spare leucine oxidation in obese subjects. Int J Obesity. 1987; 11:537-44. 152175
  243. Nair KS, Woolf PD, Welle SL, Matthew DE. Leucine, glucose, and energy metabolism after 3 days of fasting in healthy human subjects. Am J Clin Nutr. 1987; 46:557-62. 152177
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  244. Jozefowicz RF, Welle SL, Nair KS, Kingston WJ, Griggs RC. Basal metabolic rate in myotonic dystrophy: evidence against hypometabolism. Neurology. 1987;37:1021-5. 1139769
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  245. Nair KS, Webster J, Garrow JS. Effect of impaired glucose tolerance and type II diabetes on resting metabolic rate and thermic response to a glucose meal in obese women Metabolism. 1986; 35:640-4. 151965
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  246. Nair KS, Halliday D, Garrow JS. Increased energy expenditure in poorly controlled type I diabetic patients. Diabetologia. 1984; 27:13-6. 151964
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  247. Garrow JS, Scott P, Heels S, Nair KS, Halliday D. Starch blockers are ineffective in man Lancet. 1983; i:60-1. 151960
  248. Nair KS, Halliday D, Garrow JS. Thermic response to isoenergetic protein, carbohydrate, or fat meals in lean and obese subjects. Clin Sci l983; 65:307-12. 151961
  249. Garrow JS, Scott P, Heels S, Nair KS, Halliday D. A study of "starch blockers" in man using l3C enriched starch as a tracer. Hum 37C301-305 1983; Nutr:Clin Nutr. 151962
  250. Nair KS, Garrow JS, Ford C, Mahler RF, Halliday D. Effect of poor diabetic control and obesity on whole body protein turnover in man. Diabetologia. 1983; 25:400-3. 151963
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  251. Nair KS, Garrow JS. Depression of cellular immunity as an index of malnutrition in surgical patients. Br Med J. 1981; 282:698-9. 151957
  252. Nair KS, Garrow JS. Depression of cellular immunity. Br J Med. 1981; 282:1424. 151958
  253. Nair KS, Holdaway IM, Evans MC, Cameron AD. Magnesium and parathyroid hormone. J Endocrinol Invest. 1979; 2:267-70. 1139560
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