Publications

1. Mazzone A, Bernard CE, Strege PR, Beyder A, Galietta LJ, Pasricha PJ, Rae JL, Parkman HP, Linden DR, Szurszewski JH, Ordog T, Gibbons SJ, Farrugia G. Altered expression of Ano1 variants in human diabetic gastroparesis. J Biol Chem. 2011 Apr 15; 286(15):13393-403. Epub 2011 Feb 24. 2151679
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2. Beyder A, Rae JL, Bernard C, Strege PR, Sachs F, Farrugia G. Mechanosensitivity of Nav1.5, a voltage-sensitive sodium channel. J Physiol. 2010 Dec 15; 588(Pt 24):4969-85. Epub 2010 Nov 01. 2124145
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3. Saito YA, Strege PR, Tester DJ, Locke GR 3rd, Talley NJ, Bernard CE, Rae JL, Makielski JC, Ackerman MJ, Farrugia G. Sodium channel mutation in irritable bowel syndrome: evidence for an ion channelopathy. Am J Physiol Gastrointest Liver Physiol. 2009 Feb; 296(2):G211-8. Epub 2008 Dec 04. 1900193
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4. Goetz MP, Suman VJ, Couch FJ, Ames MM, Rae JM, Erlander MG, Ma XJ, Sgroi DC, Reynolds CA, Lingle WL, Weinshilboum RM, Flockhart DA, Desta Z, Perez EA, Ingle JN. Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: combining inherited and tumor gene markers for prediction of tamoxifen resistance. Clin Cancer Res. 2008 Sep 15; 14(18):5864-8. 1902501
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5. Rae JL, Levis RA. Fabrication of patch pipets. Current Protocols in Neuroscience. 2004 May; Chapter 6(Suppl 26):Unit 6.3. 1877013
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6. Mathias RT, Rae JL. The lens: local transport and global transparency. Exp Eye Res. 2004 Mar; 78(3):689-98. 1639213
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7. Ou Y, Gibbons SJ, Miller SM, Strege PR, Rich A, Distad MA, Ackerman MJ, Rae JL, Szurszewski JH, Farrugia G. SCN5A is expressed in human jejunal circular smooth muscle cells. Neurogastroenterol Motil. 2002 Oct; 14(5):477-86. 1316264
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8. Lyford GL, Strege PR, Shepard A, Ou YJ, Ermilov L, Miller SM, Gibbons SJ, Rae JL, Szurszewski JH, Farrugia G. alpha(1C) (Ca(v)1.2) L-type calcium channel mediates mechanosensitive calcium regulation. Am J Physiol Cell Physiol. 2002 Sep; 283(3):C1001-8. 1315242
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9. Rae JL, Levis RA. Single-cell electroporation. Pflugers Arch. 2002 Feb; 443(4):664-70. 1120978
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10. Holm AN, Rich A, Miller SM, Strege P, Ou Y, Gibbons S, Sarr MG, Szurszewski JH, Rae JL, Farrugia G. Sodium current in human jejunal circular smooth muscle cells. Gastroenterology. 2002 Jan; 122(1):178-87. 1007941
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11. Rae JL. Electroporation of single cells. Axobits. 2002; 34:7-11. 1150771
    
12. Rae JL, Shepard AR. Kv3.3 potassium channels in lens epithelium and corneal endothelium. Exp Eye Res. 2000 Mar; 70(3):339-48. 1011555
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13. Rae JL, Shepard AR. Kir2.1 Potassium channels and corneal epithelia. Curr Eye Res. 2000 Feb; 20(2):144-52. 1011554
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14. Rae JL, Levis RL. An electrode coating elastomer to replace sylgard 184. Axobits. 2000; 29:6-7. 1150770
    
15. Farrugia G, Holm AN, Rich A, Sarr MG, Szurszewski JH, Rae JL. A mechanosensitive calcium channel in human intestinal smooth muscle cells. Gastroenterology. 1999 Oct; 117(4):900-5. 1009275
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16. Shepard AR, Rae JL. Electrically silent potassium channel subunits from human lens epithelium. Am J Physiol. 1999 Sep; 277(3 Pt 1):C412-24. 1021283
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17. Shepard AR, Rae JL. "Microprep" method for rapidly isolating plasmid DNAs for restriction enzyme analysis. Biotechniques. 1999 May; 26(5):868-70. 1021281
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18. Rich A, Farrugia G, Rae JL. Effects of melatonin on ionic currents in cultured ocular tissues. Am J Physiol. 1999 Apr; 276(4 Pt 1):C923-9. 112636
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19. Shepard AR, Rae JL. Ion transporters and receptors in cDNA libraries from lens and cornea epithelia. Curr Eye Res. 1998 Jul; 17(7):708-19. 1018410
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20. Rae JL, Shepard AR. Molecular biology electrophysiology of calcium-activated potassium channels from lens epithelium. Curr Eye Res. 1998 Mar; 17(3):264-275. 1020014
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21. Rae JL, Shepard AR. Inwardly rectifying potassium channels in lens epithelium are from the IRK1 (Kir 2.1) family. Exp Eye Res. 1998 Mar; 66(3):347-59. 1018409
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22. Farrugia G, Miller SM, Rich A, Liu X, Maines MD, Rae JL, Szurszewski JH. Distribution of heme oxygenase and effects of exogenous carbon monoxide in canine jejunum. Am J Physiol. 1998 Feb; 274(2 Pt 1):G350-8. 1977581
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23. Rae JL, Shepard AR. Identification of potassium channels in human lens epithelium. Current Topics in Membranes. 1998; 45:69-104. 1020008
    
24. Levis Ra, Rae JL. Low noise patch clamp techniques. Methods in Enzumology. 1998; 293:218-66. 1150767
    
25. Shepard AR, Rae JL. Magnetic bead capture of cDNAs from double-stranded plasmid cDNA libraries. Nucleic Acids Res. 1997 Aug 1; 25(15):3183-5. 1015425
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26. Rich A, Bartling C, Farrugia G, Rae JL. Effects of PH on the potassium current in rabbit corneal epithelial cells. Am J Physiol Cell Physiol. 1997 Feb; 272(2):C 744-C 753. 101810
    
27. Mathias RT, Rae JL, Baldo GJ. Physiological properties of the normal lens. Physiol Rev. 1997 Jan; 77(1):21-50. 1015430
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28. Rae JL, Shepard AR. Chapter 4 identification of potassium channels in human lens epithelium. Curr Top Membr Transp. 1997; 45(C):69-104. 2118858
    
29. Rae JL, Watsky MA. Ionic channels in corneal endothelium. Am J Physiol Cell Physiol. 1996 Apr; 39(4):C 975-C 989. 1027481
    
30. Rae JL, Bartling C, Rae J, Mathias RT. Dye transfer between cells of the lens. J Membr Biol. 1996 Mar; 150(1):89-103. 1025783
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31. Rae JL, Watsky M. Ion channels in corneal endothelium. Am J Physiol. 1996; 270:C975-89. 1150756
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32. Farrugia G, Rich A, Rae JL, Sarr MG, Szurszewski JH. Calcium currents in human and canine jejunal circular smooth muscle cells. Gastroenterology. 1995 Sep; 109(3):707-17. 93780
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33. Rae JL, Rich A, Zamudio AC, Candia OA. Effect of Prozac on whole cell ionic currents in lens and corneal epithelia. Am J Physiol. 1995 Jul; 269(1 Pt 1):C250-6. 1022069
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34. Dewey J, Bartling C, Rae JL. A non-enzymatic method for lens decapsulation which leaves the epithelial cells attached to the fibers. Curr Eye Res. 1995 May; 14(5):357-62. 1023052
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35. Rich A, Rae JL. Calcium entry in rabbit corneal epithelial cells: evidence for a nonvoltage dependent pathway. J Membr Biol. 1995 Mar; 144(2):177-84. 1022068
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36. Rae JL. Outwardly rectifying potassium currents in lens epithelial cell membranes. Curr Eye Res. 1994 Sep; 13(9):679-86. 1031641
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37. Rich A, Farrugia G, Rae JL. Carbon monoxide stimulates a potassium-selective current in rabbit corneal epithelial cells. Am J Physiol. 1994 Aug; 267(2 Pt 1):C435-42. 88585
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38. Farrugia G, Rae JL, Sarr MG, Szurszewski JH. Potassium current in circular smooth muscle of human jejunum activated by fenamates. Am J Physiol. 1993 Nov; 265(5 Pt 1):G873-9. 84570
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39. Levis RA, Rae JL. The use of quartz patch pipettes for low noise single channel recording. Biophys J. 1993 Oct; 65(4):1666-77. 1028638
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40. Farrugia G, Rae JL, Szurszewski JH. Characterization of an outward potassium current in canine jejunal circular smooth muscle and its activation by fenamates. J Physiol. 1993 Aug; 468:297-310. 85406
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41. Rae JL. Ion channels in ocular epithelia. Invest Ophthalmol Vis Sci. 1993 Aug; 34(9):2608-12. 1028637
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42. Watsky MA, Rae JL. Ion channel involvement in the temperature-sensitive response of the rabbit corneal endothelial cell resting membrane potential. J Membr Biol. 1993 Jul; 135(1):61-71. 1028636
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43. Farrugia G, Irons WA, Rae JL, Sarr MG, Szurszewski JH. Activation of whole cell currents in isolated human jejunal circular smooth muscle cells by carbon monoxide. Am J Physiol. 1993 Jun; 264(6 Pt 1):G1184-9. 84110
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44. Farrugia G, Rae J. Effect of volume changes on a potassium current in rabbit corneal epithelial cells. Am J Physiol. 1993 May; 264(5 Pt 1):C1238-45. 83716
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45. O'Grady SM, Cooper KE, Rae JL. Regulation of a voltage-dependent, calcium-activated K conductance by cyclic GMP in dissociated flounder enterocytes. Journal of Comparative Physiology - B, Biochemical, Systemic, & Environmental Physiology. 1993; 163(7):581-6. 1028644
    
46. Cooper K, Watsky M, Rae JL. Potassium currents from isolated frog lens epithelia cells. Exp Eye Res. 1992 Dec; 55:861-868. 1027882
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47. Farrugia G, Rae JL. Regulation of a potassium-selective current in rabbit corneal epithelium by cyclic GMP, carbachol and diltiazem. J Membr Biol. 1992 Jul; 129(1):99-107. 80660
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48. Rae JL, Farrugia G. Whole-cell potassium current in rabbit corneal epithelium activated by fenamates. J Membr Biol. 1992 Jul; 129(1):81-97. 80661
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49. Watsky MA, Rae JL. Dye coupling in the corneal endothelium: effects of ouabain and extracellular calcium removal. Cell & Tissue Research. 1992 Jul; 269(1):57-63. 1039315
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50. Watsky MA, Cooper K, Rae JL. Transient outwardly rectifying potassium channel in the rabbit corneal endothelium. J Membr Biol. 1992 Jun; 128(2):123-32. 1039314
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51. Watsky MA, Rae JL. Initial characterization of whole-cell currents from freshly dissociated corneal keratocytes. Curr Eye Res. 1992 Feb; 11(2):127-34. 1039313
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52. Rae JL, Dewey J, Rae S. The large conductance potassium ion channel of rabbit corneal epithelium is blocked by quinidine. Invest Ophthalmol Vis Sci. 1992; 33:286-90. 1150721
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53. Rae JL, Levis RA. A method for exceptionally low noise single channel recordings. Pflugers Arch. 1992; 420:618-20. 1150722
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54. Rae JL, Levis RA. A technique for ultra low noise single-channel recording using an Axopatch 200A, quartz pipettes, and silicone fluid. Axobits. 1992; 11:9-12. 1150723
    
55. Rae JL, Mathias RT, Cooper K, Baldo G. Divalent cation effects on lens conductance and stretch-activated cation channels. Exp Eye Res. 1992; 55:135-44. 1150724
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56. Rae JL, Rae S. Whole-cell currents from nonculturedhuman lens epithelium. Invest Ophthalmol. 1992; 33(7):2262-8. 1150725
    
57. Levis RA, Rae JL. Construction a patch clamp setup. Methods Enzymol. 1992; 207:14-66. 1027877
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58. Rae JL, Levis RA. Glass technology for patch clamp electrodes. Methods Enzymol. 1992; 207:66-92. 1039318
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59. Mathias RT, Riquelme G, Rae JL. Cell to cell communication and pH in the frog lens. J Gen Physiol. 1991 Dec; 98(6):1085-103. 1036532
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60. Rae J, Cooper K, Gates P, Watsky M. Low access resistance perforated patch recordings using amphotericin B. J Neurosci Methods. 1991 Mar; 37(1):15-26. 1036838
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61. O'Grady SM, Cooper KE, Rae JL. Cyclic GMP regulation of a voltage-activated K channel in dissociated enterocytes. Am J Physiol. 1991; 124:159-67. 1150704
    
62. Rae JL. Physiology of the lens 1-14 in:. Duane's Clinical Ophthalmology Tasman W Haeger EA, Editors JB Lippincott Company, 1991. 1150712
    
63. Rae JL, Fernandez J. Perforated patch recordings in physiology. NIPS. 1991; 6:273-7. 1150714
    
64. Rae JL. Perforated-patch recording techniques. Axobits. 1991; 8:6-10. 1150716
    
65. Watsky MA, Rae JL. Resting voltage measurements of the rabbit corneal endothelium using patch-current clampo techiniques. Invest Ophthalmol Vis Sci. 1991; 32:106-11. 1150720
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66. Rae JL, Dewey J, Rae JS, Cooper K. A maxi calcium-activated potassium channel from chick lens epithelium. Curr Eye Res. 1990 Sep; 9(9):847-61. 1150633
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67. Rae JL, Dewey J, Rae S, Nesler M, Cooper K. Single potassium channels in corneal epithelium. Invest Ophthalmol Vis Sci (9):1799-1809 1990; 1990:31. 1150634
    
68. Cooper K, Gates P, Rae JL, Dewey J. Electroscopy of cultured human lens epithelial cells. J Membr Biol. 1990; 117:285-98. 1150629
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69. Rae JL, Cooper K. New techniques for the study of lens electrophysiology. Exp Eye Res. 1990; 50:603-14. 1150630
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70. Rae JL, Dewey J, Cooper K, Gates P. Potassium channel in rabbit corneal endothelium activated by external anions. J Membr Biol 1990; 114:29-36. J Membr Biol. 1990; 114:29-36. 1150631
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71. Rae JL, Dewey J, Cooper K, Gates P. A non-selective cation channel in rabbit corneal endothelium activated by internal calcium and inhibited by internal ATP. Exp Eye Res. 1990; 50:373-84. 1150632
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72. Gates P, Cooper K, Rae JL, Eisenberg RS. Predictions of diffusion models for one-ion membrane channels. Prog Biophys Molec Biol. 1989; 53:153-96. 1150620
    
73. Rae JL, Cooper KE. Potassium channels in chick lens epithelium change with maturation. Lens and Eye Toxicity Research. 1989; 6:833-43. 1150624
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74. Cooper K, Rae JL, Gates P. Membrane and junctional properties of dissociaed frog lens epithelial cells. J Membr Biol. 1989; 11:215-27. 1150618
    
75. Rae JL, Dewey J, Cooper K. Properties of single potassium-selective ionic channels from the apical membrane of rabbit corneal endothelium. Exp Eye Res. 1989; 49:591-609. 1150627
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76. Rae JL, Lewno AW, Cooper K, Gates P. Dye and electrical coupling between cells of the rabbit corneal endothelium. Curr Eye Res. 1989; 8:859-69. 1150628
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77. Rae JL. Pharmacologic blockade of ionic channels in lens membranes. Ophthalmic Res. 1988; 20(3):132-8. 1042117
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78. Cooper KE, Tang JM, Rae JL, Eisenberg RS. A cation channel in frog lens epithelia responsive to pressue and calcium. J Memb Biol. 1986; 93:259-69. 1150606
    
79. Rae JL. Potassium channels from chick lens epithelium. Federation Proc. 1986; 45:2718-22. 1150611
    
80. Kuszak JR, Macsai MS, Bloom KJ, Rae JL, Weinstein RS. Cell-to-cell fusions of lens fiber cells in situ: correlative light, scanning electron microscopy and freeze-fracture studies. J Ultrastrct Res. 1985; 93:144-60. 1150585
    
81. Kuszak JR, Shek YH, Carney KC, Rae JL. A correlative freeze-etch and electrophysiological study of communicating functions in crystalline lenses. Cur Eye Res. 1985; 4:1145-53. 1150592
    
82. Mathias RT, Rae JL. Steady state voltages in the frog lens. Cur Eye Res. 1985; 4:421-30. 1150597
    
83. Mathias RT, Rae JL. Transport properties of the lens. Am J Physiol 249 1985. 1150600
    
84. Mathias RT, Rae JL. Transport properties of the lens. Cell Physiol. 1985; 18:C181-90. 1150601
    
85. Mathias Rt, Rae JL, Ebihara L, McCarthy RT. The localization of transport properties in the frog lens. Biophys J. 1985; 48:423-34. 1150603
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86. Rae JL. The application of patch clamp methods to ocular epithelia. Cur Eye Res. 1985; 4:409-20. 1150604
    
87. Rae JL. The patch voltage clamp: its application to lens research. Lens Research. 1984; 2:61-87. 1150571
    
88. Rae JL, Levis Ra. Patch clamp recordings from the epithelium of the lens obtained using glass selected for low noise and improved sealing proerties. Biophys J. 1984; 45:144-6. 1150573
    
89. Rae JL, Levis RA. Patch voltage clamp of lens epithelial cells: theory and practice. Molec Physiol. 1984; 6:115-62. 1150577
    
90. Kuszak JR, Bertram BA, Macsai MS, Rae JL. Sutures of the crystalline lens: a review. Scanning Electron Microscopy. 1984; 3:1369-78. 1150566
    
91. Rae JL, Truitt K, Kuszak J. The use of procion dyes for light microscopy of the frog lens. Invest Ophthal and Vis Sci. 1983; 24:1167-71. 1150565
    
92. Kuszak J, Macsai MS, Rae JL. Sero scanning electron microscopy of the crystalline lens. Scanning Electron Microscopy. 1983; 3:1415-25. 1150557
    
93. Rae JL, Kuszak JR. The electrical coupling of epithelium and fibers in the frog lens. Exp Eye Res. 1983; 36:317-26. 1150560
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94. Rae JL, Thompson RD, Eisenberg RS. The effect of 2-4 dinitrophenol on cell to cell communication in the frog lens. Exp Eye Res. 1982; 35:597-609. 1150553
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95. Rae JL, Truitt KD, Kuszak JR. A simple fluorescence technique for light microscopy of the crystalline lens. Curr Eye Res. 1982; 2:1-5. 1150555
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96. Kuszak J, Rae JL. Scanning electron microscopy of the frog lens. Exp Eye Res. 1982; 35:499-519. 1150544
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97. Kuszak JR, Rae JL, Pauli BU, Weinstein RS. Rotary replication of lens gap junctions. J Ultrastrc Res. 1982; 81:249-56. 1150547
    
98. Rae JL, Mathias RT, Eisenberg RS. Physiological role of the membranes and extracellular space within the ocular lens. Exp Eye Res. 1982; 35:471-89. 1150550
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99. Mathias RT, Rae JL, Eisenberg RS. The lens as a nonuniform spherical syncytium. Biophys J. 1981; 34:61-83. 1150540
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100. Koblasz A, Rae JL, Correia MJ, NI MD. Weinder Kernels and Frequency Response Functions for the Human Retina. IEEE - Biomedical. 1980. Vol BME 27:68-75. 1150525
     
101. Rae JL, Stacey T. Lanthanum and procion yellow as extracellular markers in the crystalline lens of the rat. Exp Eye Res. 1979; 28:1-21. 1150516
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102. Mathias RT, Rae JL, Eisenberg RS. Electrical properties of structural components of the crystalline lens 1979. Biophys J. 1979; 181-21. 1150518
     
103. Eisenberg RS, Mathias RT, Rae JL. Measurement, modeling, and analysis of the linear electric properties of cells. Ann New York Acad Science. 1977; 303:342-54. 1150467
     
104. Rae JL, Riddle WR, Law WC, Welford NT. A biphasic 60-Hz synchronizer circuit for the recording of visually evoked responses in high-noise environments. Behavior Research Methods and Instrumentation. 1977; 9:341-4. 1150476
     
105. Ni MD, Correia MJ, Rae JL, Koblasz AJ. A realtime mini-computer program for calculation of frequency responses function and conherence funtion using digital fourier methods. Proceedings of Mima Montreal International Show and Symposia and Mini and Micro Computers, Montreal, Canada. 1977. 1150481
     
106. Eisenberg RS, Rae JL. Current-voltage relationships in the crystalline lens. J Physiol. 1976; 262:285-300. 1150461
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107. Rae JL, Stacey T. Intracellular markers in the crystalline lens of the rat. Documenta Ophthalomologica Proceedings Series Progress of Lens Biochemistry Research 233-9 1976. 1150463
     
108. Rae JL. The movement of procion dye in the crystalline lens. Invest Ophthal. 1974; 13:147-50. 1150438
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109. Rae JL, Germer HA. Junction potentials in the crystalline lens. L Appl Physiol. 1974; 37:464-67. 1150443
     
110. Neville MC, Paterson CA, Rae JL, Woessner DE. Nuclear magnetic resonance studies and water 'ordering' in the crystalline lens. Science. 1974; 184:1072-74. 1150452
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111. Paterson CA, Rae JL. The potential difference of the rabbit lens. Exp Eye Res. 1974; 15:507-8. 1150454
     
112. Rae JL. Potential Profiles in the crystalline lens. Exp Eye Res. 1974; 19:227-34. 1150457
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113. Rae JL. Voltage compartments in the lens. Exp Eye Res. 1974; 19:235-42. 1150459
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114. Rae JL, Blankenship JE. Bioelectric measurements in the frog lens. Exp Eye Res. 1973; 15:269-77. 1150422
     
115. Rae JL. The potential difference of the frog lens. Exp Eye Res. 1973; 15:485-94. 1150433
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116. Rae JL, Hoffert JR, Fromm PO. Studies on the normal lens potentila of the rainbow trout (Salmo gairdneri). Exp Eye Res. 1970; 10:93-101. 1150421
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