Publications

Nicks KM, Amin S, Melton LJ 3rd, Atkinson EJ, McCready LK, Riggs BL, Engelke K, Khosla S. Three-dimensional structural analysis of the proximal femur in an age-stratified sample of women. Bone. 2013 Jul; 55(1):179-88. Epub 2013 Feb 26. 2311167
View PubMed
Riggs BL, Khosla S, Melton LJ 3rd. Better tools for assessing osteoporosis. J Clin Invest. 2012 Dec 03; 122(12):4323-4. 2293280
View PubMed
Nicks KM, Amin S, Atkinson EJ, Riggs BL, Melton LJ 3rd, Khosla S. Relationship of age to bone microstructure independent of areal bone mineral density. J Bone Miner Res. 2012 Mar; 27(3):637-44. 2206701
View PubMed
Srinivasan B, Kopperdahl DL, Amin S, Atkinson EJ, Camp J, Robb RA, Riggs BL, Orwoll ES, Melton LJ 3rd, Keaveny TM, Khosla S. Relationship of femoral neck areal bone mineral density to volumetric bone mineral density, bone size, and femoral strength in men and women. Osteoporos Int. 2012 Jan; 23(1):155-62. Epub 2011 Nov 05. 2204864
View PubMed
Melton LJ 3rd, Riggs BL, Muller R, Achenbach SJ, Christen D, Atkinson EJ, Amin S, Khosla S. Determinants of forearm strength in postmenopausal women. Osteoporos Int. 2011 Dec; 22(12):3047-54. Epub 2011 Feb 10. 2147560
View PubMed
Kirmani S, Atkinson EJ, Melton LJ 3rd, Riggs BL, Amin S, Khosla S. Relationship of testosterone and osteocalcin levels during growth. J Bone Miner Res. 2011 Sep; 26(9):2212-6. 2165276
View PubMed
Drake MT, Srinivasan B, Modder UI, Ng AC, Undale AH, Roforth MM, Peterson JM, McCready LK, Riggs BL, Khosla S. Effects of intermittent parathyroid hormone treatment on osteoprogenitor cells in postmenopausal women. Bone. 2011 Sep; 49(3):349-55. Epub 2011 May 11. 2189234
View PubMed
Amin S, Kopperdhal DL, Melton LJ 3rd, Achenbach SJ, Therneau TM, Riggs BL, Keaveny TM, Khosla S. Association of hip strength estimates by finite-element analysis with fractures in women and men. J Bone Miner Res. 2011 Jul; 26(7):1593-600. 2147448
View PubMed
Melton LJ 3rd, Marquez MA, McCready LK, Achenbach SJ, Riggs BL, Amin S, Khosla S. Trabecular bone deficits among Vietnamese immigrants. Osteoporos Int. 2011 May; 22(5):1627-31. Epub 2010 Jul 24. 2109352
View PubMed
Khosla S, Melton LJ 3rd, Riggs BL. The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: is a revision needed? J Bone Miner Res. 2011 Mar; 26(3):441-51. 2118592
View PubMed
Modder UI, Hoey KA, Amin S, McCready LK, Achenbach SJ, Riggs BL, Melton LJ 3rd, Khosla S. Relation of age, gender, and bone mass to circulating sclerostin levels in women and men. J Bone Miner Res. 2011 Feb; 26(2):373-9. 2165299
View PubMed
Modder UI, Clowes JA, Hoey K, Peterson JM, McCready L, Oursler MJ, Riggs BL, Khosla S. Regulation of circulating sclerostin levels by sex steroids in women and in men. J Bone Miner Res. 2011 Jan; 26(1):27-34. 2002070
View PubMed
Undale A, Srinivasan B, Drake M, McCready L, Atkinson E, Peterson J, Riggs BL, Amin S, Modder UI, Khosla S. Corrigendum to "Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women" [Bone 47 (2010) 83-92]. Bone. 2011; 48(3):671. 2151440
Drake MT, Srinivasan B, Modder UI, Peterson JM, McCready LK, Riggs BL, Dwyer D, Stolina M, Kostenuik P, Khosla S. Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. J Clin Endocrinol Metab. 2010 Nov; 95(11):5056-62. Epub 2010 Jul 14. 2106724
View PubMed
Melton LJ 3rd, Riggs BL, Keaveny TM, Achenbach SJ, Kopperdahl D, Camp JJ, Rouleau PA, Amin S, Atkinson EJ, Robb RA, Therneau TM, Khosla S. Relation of vertebral deformities to bone density, structure, and strength. J Bone Miner Res. 2010 Sep; 25(9):1922-30. 2115603
View PubMed
Undale A, Srinivasan B, Drake M, McCready L, Atkinson E, Peterson J, Riggs BL, Amin S, Modder UI, Khosla S. Circulating osteogenic cells: characterization and relationship to rates of bone loss in postmenopausal women. Bone. 2010 Jul; 47(1):83-92. Epub 2010 Mar 31. 1997876
View PubMed
Melton LJ 3rd, Christen D, Riggs BL, Achenbach SJ, Muller R, van Lenthe GH, Amin S, Atkinson EJ, Khosla S. Assessing forearm fracture risk in postmenopausal women. Osteoporos Int. 2010 Jul; 21(7):1161-9. Epub 2009 Aug 28. 2155608
View PubMed
Keaveny TM, Kopperdahl DL, Melton LJ 3rd, Hoffmann PF, Amin S, Riggs BL, Khosla S. Age-dependence of femoral strength in white women and men. J Bone Miner Res. 2010 May; 25(5):994-1001. 2103994
View PubMed
Modder UI, Achenbach SJ, Amin S, Riggs BL, Melton LJ 3rd, Khosla S. Relation of serum serotonin levels to bone density and structural parameters in women. J Bone Miner Res. 2010 Feb; 25(2):415-22. 2118438
View PubMed
Riggs BL. Bone turnover in age-related osteoporosis: early contributions of Pierre Delmas. Osteoporos Int. 2009 Aug; 20(8):1289-90. 1977254
View PubMed
Kirmani S, Christen D, van Lenthe GH, Fischer PR, Bouxsein ML, McCready LK, Melton LJ 3rd, Riggs BL, Amin S, Muller R, Khosla S. Bone structure at the distal radius during adolescent growth. J Bone Miner Res. 2009 Jun; 24(6):1033-42. 1951271
View PubMed
Clowes JA, Eghbali-Fatourechi GZ, McCready L, Oursler MJ, Khosla S, Riggs BL. Estrogen action on bone marrow osteoclast lineage cells of postmenopausal women in vivo. Osteoporos Int. 2009 May; 20(5):761-9. Epub 2008 Sep 04. 1915693
View PubMed
Melton LJ 3rd, Riggs BL, Leibson CL, Achenbach SJ, Camp JJ, Bouxsein ML, Atkinson EJ, Robb RA, Khosla S. A bone structural basis for fracture risk in diabetes. J Clin Endocrinol Metab. 2008 Dec; 93(12):4804-9. Epub 2008 Sep 16. 1913926
View PubMed
Khosla S, Amin S, Singh RJ, Atkinson EJ, Melton LJ 3rd, Riggs BL. Comparison of sex steroid measurements in men by immunoassay versus mass spectroscopy and relationships with cortical and trabecular volumetric bone mineral density. Osteoporos Int. 2008 Oct; 19(10):1465-71. Epub 2008 Mar 13. 1901864
View PubMed
Riggs BL, Seeman E. Pierre D Delmas. J Bone Miner Res. 2008 Oct; 23(10):1539-40. 1915641
View PubMed
Syed FA, Oursler MJ, Hefferanm TE, Peterson JM, Riggs BL, Khosla S. Effects of estrogen therapy on bone marrow adipocytes in postmenopausal osteoporotic women. Osteoporos Int. 2008 Sep; 19(9):1323-30. Epub 2008 Feb 15. 1915949
View PubMed
Riggs BL, Melton LJ, Robb RA, Camp JJ, Atkinson EJ, McDaniel L, Amin S, Rouleau PA, Khosla S. A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men. J Bone Miner Res. 2008 Feb; 23(2):205-14. 1872210
View PubMed
Melton LJ 3rd, Riggs BL, Keaveny TM, Achenbach SJ, Hoffmann PF, Camp JJ, Rouleau PA, Bouxsein ML, Amin S, Atkinson EJ, Robb RA, Khosla S. Structural determinants of vertebral fracture risk. J Bone Miner Res. 2007 Dec; 22(12):1885-92. 1859056
View PubMed
Melton LJ 3rd, Riggs BL, van Lenthe GH, Achenbach SJ, Muller R, Bouxsein ML, Amin S, Atkinson EJ, Khosla S. Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Miner Res. 2007 Sep; 22(9):1442-8. 1846537
View PubMed
Amin S, Riggs BL, Melton LJ 3rd, Achenbach SJ, Atkinson EJ, Khosla S. High serum IGFBP-2 is predictive of increased bone turnover in aging men and women. J Bone Miner Res. 2007 Jun; 22(6):799-807. 1827925
View PubMed
Charatcharoenwitthaya N, Khosla S, Atkinson EJ, McCready LK, Riggs BL. Effect of blockade of TNF-alpha and interleukin-1 action on bone resorption in early postmenopausal women. J Bone Miner Res. 2007 May; 22(5):724-9. 1820526
View PubMed
Melton LJ 3rd, Riggs BL, Achenbach SJ, Amin S, Camp JJ, Rouleau PA, Robb RA, Oberg AL, Khosla S. Does reduced skeletal loading account for age-related bone loss? J Bone Miner Res. 2006 Dec; 21(12):1847-55. 1794492
View PubMed
Bouxsein ML, Melton LJ 3rd, Riggs BL, Muller J, Atkinson EJ, Oberg AL, Robb RA, Camp JJ, Rouleau PA, McCollough CH, Khosla S. Age- and sex-specific differences in the factor of risk for vertebral fracture: a population-based study using QCT. J Bone Miner Res. 2006 Sep; 21(9):1475-82. 1779673
View PubMed
Khosla S, Melton LJ 3rd, Achenbach SJ, Oberg AL, Riggs BL. Hormonal and biochemical determinants of trabecular microstructure at the ultradistal radius in women and men. J Clin Endocrinol Metab. 2006 Mar; 91(3):885-91. Epub 2005 Dec 20. 1752384
View PubMed
Riggs BL, Melton LJ 3rd, Robb RA, Camp JJ, Atkinson EJ, Oberg AL, Rouleau PA, McCollough CH, Khosla S, Bouxsein ML. Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures. J Bone Miner Res. 2006 Feb; 21(2):315-23. Epub 2005 Oct 31. 1747094
View PubMed
Khosla S, Riggs BL, Atkinson EJ, Oberg AL, McDaniel LJ, Holets M, Peterson JM, Melton LJ 3rd. Effects of sex and age on bone microstructure at the ultradistal radius: a population-based noninvasive in vivo assessment. J Bone Miner Res. 2006 Jan; 21(1):124-31. Epub 2005 Oct 03. 2230116
View PubMed
Melton LJ 3rd, Wenger DE, Atkinson EJ, Achenbach SJ, Berquist TH, Riggs BL, Jiang G, Eastell R. Influence of baseline deformity definition on subsequent vertebral fracture risk in postmenopausal women. Osteoporos Int. 2006; 17(7):978-85. Epub 2006 Apr 28. 1765660
View PubMed
Khosla S, Riggs BL. Pathophysiology of age-related bone loss and osteoporosis. Endocrinology & Metabolism Clinics of North America. 2005 Dec; 34(4):1015-30. 1743612
View PubMed
Melton LJ, Looker AC, Shepherd JA, O'Connor MK, Achenbach SJ, Riggs BL, Khosla S. Osteoporosis assessment by whole body region vs. site-specific DXA. Osteoporos Int. 2005 Dec; 16(12):1558-64. 1743576
View PubMed
Clowes JA, Riggs BL, Khosla S. The role of the immune system in the pathophysiology of osteoporosis. Immunol Rev. 2005 Dec; 208:207-27. 1736632
View PubMed
Khosla S, Riggs BL, Robb RA, Camp JJ, Achenbach SJ, Oberg AL, Rouleau PA, Melton LJ 3rd. Relationship of volumetric bone density and structural parameters at different skeletal sites to sex steroid levels in women. J Clin Endocrinol Metab. 2005 Sep; 90(9):5096-103. Epub 2005 Jul 05. 1729753
View PubMed
Eghbali-Fatourechi GZ, Lamsam J, Fraser D, Nagel D, Riggs BL, Khosla S. Circulating osteoblast-lineage cells in humans. N Engl J Med. 2005 May 12; 352(19):1959-66. 1713267
View PubMed
Melton LJ 3rd, Beck TJ, Amin S, Khosla S, Achenbach SJ, Oberg AL, Riggs BL. Contributions of bone density and structure to fracture risk assessment in men and women. Osteoporos Int. 2005 May; 16(5):460-7. 1718773
View PubMed
Khosla S, Melton LJ 3rd, Robb RA, Camp JJ, Atkinson EJ, Oberg AL, Rouleau PA, Riggs BL. Relationship of volumetric BMD and structural parameters at different skeletal sites to sex steroid levels in men. J Bone Miner Res. 2005 May; 20(5):730-40. 1721379
View PubMed
Melton LJ 3rd, Atkinson EJ, Khosla S, Oberg AL, Riggs BL. Evaluation of a prediction model for long-term fracture risk. J Bone Miner Res. 2005 Apr; 20(4):551-6. Epub 2004 Dec 06. 1703788
View PubMed
Riggs BL, Parfitt AM. Drugs used to treat osteoporosis: the critical need for a uniform nomenclature based on their action on bone remodeling. J Bone Miner Res. 2005 Feb; 20(2):177-84. Epub 2004 Nov 16. 1680872
View PubMed
Sanyal A, Riggs BL, Spelsberg TC, Khosla S. Bone marrow stromal cells express two distinct splice variants of ER-alpha that are regulated by estrogen. J Cell Biochem. 2005 Jan 1; 94(1):88-97. 1677849
View PubMed
Nagel DE, Khosla S, Sanyal A, Rosen DM, Kumagai Y, Riggs BL. A fragment of the hypophosphatemic factor, MEPE, requires inducible cyclooxygenase-2 to exert potent anabolic effects on normal human marrow osteoblast precursors. J Cell Biochem. 2004 Dec 15; 93(6):1107-14. 1674517
View PubMed
Riggs BL, Melton LJ, Robb RA, Camp JJ, Atkinson EJ, Peterson JM, Rouleau PA, McCollough CH, Bouxsein ML, Khosla S. Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res. 2004 Dec; 19(12):1945-54. 1674518
View PubMed
Modder UIL, Riggs BL, Spelsberg TC, Fraser DG, Atkinson EJ, Arnold R, Khosla S. Dose-response of estrogen on bone versus the uterus in ovariectomized mice. European Journal of Endocrinology. 2004 Oct; 151(4):503-10. 1673809
View PubMed
Johnson GB, Riggs BL, Platt JL. A genetic basis for the "Adonis" phenotype of low adiposity and strong bones. FASEB J. 2004 Aug; 18(11):1282-4. Epub 2004 Jun 18. 1694001
View PubMed
Doran PM, Turner RT, Chen D, Facteau SM, Ludvigson JM, Khosla S, Riggs BL, Russell SJ. Native osteoprotegerin gene transfer inhibits the development of murine osteolytic bone disease induced by tumor xenografts. Exp Hematol. 2004 Apr; 32(4):351-9. 1649269
View PubMed
Modder UI, Sanyal A, Kearns AE, Sibonga JD, Nishihara E, Xu J, O'Malley BW, Ritman EL, Riggs BL, Spelsberg TC, Khosla S. Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology. 2004 Feb; 145(2):913-21. Epub 2003 Oct 16. 1517964
View PubMed
Monroe DG, Getz BJ, Johnsen SA, Riggs BL, Khosla S, Spelsberg TC. Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERalpha or ERbeta. J Cell Biochem. 2003 Oct 1; 90(2):315-26. 1417032
View PubMed
Rickard DJ, Monroe DG, Ruesink TJ, Khosla S, Riggs BL, Spelsberg TC. Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors alpha and beta. J Cell Biochem. 2003 Jun 1; 89(3):633-46. 1355740
View PubMed
Eghbali-Fatourechi G, Khosla S, Sanyal A, Boyle WJ, Lacey DL, Riggs BL. Role of RANK ligand in mediating increased bone resorption in early postmenopausal women. J Clin Invest. 2003 Apr; 111(8):1221-30. 1340490
View PubMed
Vincent A, Riggs BL, Atkinson EJ, Oberg AL, Khosla S. Effect of estrogen replacement therapy on parathyroid hormone secretion in elderly postmenopausal women. Menopause. 2003 Mar-Apr; 10(2):165-71. 1325093
View PubMed
Monroe DG, Johnsen SA, Subramaniam M, Getz BJ, Khosla S, Riggs BL, Spelsberg TC. Mutual antagonism of estrogen receptors alpha and beta and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines. J Endocrinol. 2003 Mar; 176(3):349-57. 1328712
View PubMed
Rickard DJ, Waters KM, Ruesink TJ, Khosla S, Katzenellenbogen JA, Katzenellenbogen BS, Riggs BL, Spelsberg TC. Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts. J Bone Miner Res. 2002 Apr; 17(4):580-92. 1120940
View PubMed
Clarke BL, Ebeling PR, Jones JD, Wahner HW, O'Fallon WM, Riggs BL, Fitzpatrick LA. Predictors of bone mineral density in aging healthy men varies by skeletal site. Calcif Tissue Int. 2002 Mar; 70(3):137-45. 1120954
View PubMed
Heshmati HM, Khosla S, Robins SP, O'Fallon WM, Melton LJ, Riggs BL. Role of low levels of endogenous estrogen in regulation of bone resorption in late postmenopausal women. J Bone Miner Res. 2002 Jan; 17(1):172-8. 1007853
View PubMed
Melton LJ, Marquez MA, Achenbach SJ, Tefferi A, O'Connor MK, O'Fallon WM, Riggs BL. Variations in bone density among persons of African heritage. Osteoporos Int. 2002; 13(7):551-9. 1314984
View PubMed
Locklin RM, Riggs BL, Hicok KC, Horton HF, Byrne MC, Khosla S. Assessment of gene regulation by bone morphogenetic protein 2 in human marrow stromal cells using gene array technology. J Bone Miner Res. 2001 Dec; 16(12):2192-204. 1006946
View PubMed
Doran PM, Riggs BL, Atkinson EJ, Khosla S. Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men. J Bone Miner Res. 2001 Nov; 16(11):2118-25. 1006391
View PubMed
Khosla S, Melton LJ, Riggs BL. Estrogens and bone health in men. Calcif Tissue Int. 2001 Oct; 69(4):189-92. 1006643
View PubMed
Waters KM, Rickard DJ, Riggs BL, Khosla S, Katzenellenbogen JA, Katzenellenbogen BS, Moore J, Spelsberg TC. Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform. J Cell Biochem. 2001 Aug 21-Sep 5; 83(3):448-62. 1006699
View PubMed
Yan T, Riggs BL, Boyle WJ, Khosla S. Regulation of osteoclastogenesis and RANK expression by TGF-beta1. J Cell Biochem. 2001 Aug 1-9; 83(2):320-5. 1003784
View PubMed
Burguera B, Hofbauer LC, Thomas T, Gori F, Evans GL, Khosla S, Riggs BL, Turner RT. Leptin reduces ovariectomy-induced bone loss in rats. Endocrinology. 2001 Aug; 142(8):3546-53. 1005985
View PubMed
Thomas T, Burguera B, Melton LJ 3rd, Atkinson EJ, O'Fallon WM, Riggs BL, Khosla S. Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women. Bone. 2001 Aug; 29(2):114-20. 1006203
View PubMed
Hofbauer LC, Shui C, Riggs BL, Dunstan CR, Spelsberg TC, O'Brien T, Khosla S. Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells. Biochem Biophys Res Commun. 2001 Jan 12; 280(1):334-9. 1003531
View PubMed
Marquez MA, Melton LJ 3rd, Muhs JM, Crowson CS, Tosomeen A, O'Connor MK, O'Fallon WM, Riggs BL. Bone density in an immigrant population from Southeast Asia. Osteoporos Int. 2001; 12(7):595-604. 1006204
View PubMed
Bell NH, Williamson BT, Hollis BW, Riggs BL. Effects of race on diurnal patterns of renal conservation of calcium and bone resorption in premenopausal women. Osteoporos Int. 2001; 12(1):43-8. 1003975
View PubMed
Riggs BL, Baron R, Boyle WJ, Drezner M, Manolagas S, Martin TJ, Stewart AF, Suda T, Yasuda H, Aubin J, Goltzman D. Proposed standard nomenclature for new tumor necrosis factor family members involved in the regulation of bone resorption. J Bone Miner Res. 2000 Dec; 15(12):2293-2296. 140487
View PubMed
Gori F, Hofbauer LC, Dunstan CR, Spelsberg TC, Khosla S, Riggs BL. The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated. Endocrinology. 2000 Dec; 141(12):4768-76. 140433
View PubMed
Riggs L, Baron R, Boyle WJ, Drezner M, Manolagas S, Martin TJ, Stewart AF, Suda T, Yasuda H, Aubin J, Goltzman DDD. Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption. Bone. 2000 Dec; 27(6):761-764. 1013587
View PubMed
Falahati-Nini A, Riggs BL, Atkinson EJ, O'Fallon WM, Eastell R, Khosla S. Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J Clin Invest. 2000 Dec; 106(12):1553-60. 1013555
View PubMed
Pattanaungkul S, Riggs BL, Yergey AL, Vieira NE, O'Fallon WM, Khosla S. Relationship of intestinal calcium absorption to 1,25-dihydroxyvitamin D [1,25(OH)(2)D] levels in young versus elderly women: evidence for age-related intestinal resistance to 1,25(OH)(2)D action. J Clin Endocrinol Metab. 2000 Nov; 85(11):4023-4027. 1014615
View PubMed
Thomas T, Burguera B, Melton LJ 3rd, Atkinson EJ, O'Fallon WM, Riggs BL, Khosla S. Relationship of serum leptin levels with body composition and sex steroid and insulin levels in men and women. Metabolism. 2000 Oct; 49(10):1278-84. 139252
View PubMed
Melton LJ 3rd, Khosla S, Crowson CS, O'Connor MK, O'Fallon WM, Riggs BL. Epidemiology of sarcopenia. J Am Geriatr Soc. 2000 Jun; 48(6):625-30. 134117
View PubMed
Hefferan TE, Subramaniam M, Khosla S, Riggs BL, Spelsberg TC. Cytokine-specific induction of the TCF-beta inducible early gene (TIEG): regulation by specific members of the TGF-beta family. J Cell Biochem. 2000 Jun; 78(3):380-390. 136597
View PubMed
Hofbauer LC, Khosla S, Dunstan CR, Lacey DL, Boyle WJ, Riggs BL. The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. J Bone Miner Res. 2000 Jan; 15(1):2-12. 126098
View PubMed
Melton LJ 3rd, Atkinson EJ, O'Connor MK, O'Fallon WM, Riggs BL. Determinants of bone loss from the femoral neck in women of different ages. J Bone Miner Res. 2000 Jan; 15(1):24-31. 126099
View PubMed
Melton LJ III, Khosla S, Riggs BL. Epidemiology of sarcopenia. Mayo Clin Proc. 2000 Jan; 75(Suppl):S10-3. 137218
View PubMed
Riggs BL, Khosla S, Melton LJ III. Primary osteoporosis in men: role of sex steroid deficiency... Workshop "Is There a Case for Testosterone Replacement in Elderly Men?" held in Palm Springs, Calif, March 17-19, 1999. Mayo Clin Proc. 2000 Jan; 75(Suppl):S46-50. 137223
View PubMed
Proctor DN, Melton LJ, Khosla S, Crowson CS, O'Connor MK, Riggs BL. Relative influence of physical activity, muscle mass and strength on bone density. Osteoporos Int. 2000; 11(11):944-52. 1013736
View PubMed
Melton LJ 3rd, Khosla S, Achenbach SJ, O'Connor MK, O'Fallon WM, Riggs BL. Effects of body size and skeletal site on the estimated prevalence of osteoporosis in women and men. Osteoporos Int. 2000; 11(11):977-83. 1013613
View PubMed
Melton LJ 3rd, Khosla S, Atkinson EJ, Oconnor MK, Ofallon WM, Riggs BL. Cross-sectional versus longitudinal evaluation of bone loss in men and women. Osteoporos Int. 2000; 11(7):592-9. 139448
View PubMed
Thomas T, Gori F, Spelsberg TC, Khosla S, Riggs BL, Conover CA. Response of bipotential human marrow stromal cells to insulin-like growth factors: effect on binding protein production, proliferation, and commitment to osteoblasts and adipocytes. Endocrinology. 1999 Nov; 140(11):5036-44. 123364
View PubMed
Khosla S, Melton LJ 3rd, Wermers RA, Crowson CS, O'Fallon WM, Riggs BL. Primary hyperparathyroidism and the risk of fracture: a population-based study. J Bone Miner Res. 1999 Oct; 14(10):1700-7. 1009141
View PubMed
Hofbauer LC, Gori F, Riggs BL, Lacey DL, Dunstan CR, Spelsberg TC, Khosla S. Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology. 1999 Oct; 140(10):4382-9. 1009443
View PubMed
Hofbauer LC, Khosla S, Dunstan CR, Lacey DL, Spelsberg TC, Riggs BL. Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology. 1999 Sep; 140(9):4367-70. 1314493
View PubMed
Hofbauer LC, Lacey DL, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S. Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. Bone. 1999 Sep; 25(3):255-9. 1009068
View PubMed
Miller PD, Baran DT, Bilezikian JP, Greenspan SL, Lindsay R, Riggs BL, Watts NB. Practical clinical application of biochemical markers of bone turnover: Consensus of an expert panel. J Clin Densitom. 1999 Fall; 2(3):323-42. 1010063
View PubMed
Gori F, Thomas T, Hicok KC, Spelsberg TC, Riggs BL. Differentiation of human marrow stromal precursor cells: bone morphogenetic protein-2 increases OSF2/CBFA1, enhances osteoblast commitment, and inhibits late adipocyte maturation. J Bone Miner Res. 1999 Sep; 14(9):1522-35. 1011349
View PubMed
Spelsberg TC, Subramaniam M, Riggs BL, Khosla S. The actions and interactions of sex steroids and growth factors cytokines on the skeleton. Mol Endocrinol. 1999 Jun; 13(6):819-28. 115940
View PubMed
Thomas T, Gori F, Khosla S, Jensen MD, Burguera B, Riggs BL. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology. 1999 Apr; 140(4):1630-8. 110796
View PubMed
Colford JW, Lueddecke BA, Salvati M, Hanna D, Sailer D, Khosla S, Riggs BL, Langman CB. Immunoradiometric assay for intact human osteocalcin(1-49) without cross-reactivity to breakdown products. Clin Chem. 1999 Apr; 45(4):526-31. 114406
View PubMed
Pederson L, Kremer M, Judd J, Pascoe D, Spelsberg TC, Riggs BL, Oursler MJ. Androgens regulate bone resorption activity of isolated osteoclasts in vitro. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):505-10. 109198
View PubMed
Melton LJ 3rd, Atkinson EJ, Khosla S, O'Fallon WM, Riggs BL. Secondary osteoporosis and the risk of vertebral deformities in women. Bone. 1999 Jan; 24(1):49-55. 108980
View PubMed
Nickelsen T, Lufkin EG, Riggs BL, Cox DA, Crook TH. Raloxifene hydrochloride, a selective estrogen receptor modulator: safety assessment of effects on cognitive function and mood in postmenopausal women. Psychoneuroendocrinology. 1999 Jan; 24(1):115-28. 109031
View PubMed
Hofbauer LC, Gori F, Riggs BL, Dunstan CR, Lacey DL, Spelserg TC, Khosla S. Stimulation of osteoprotegerin lingnd and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential mechanisms of glucocoticoid-induced osteoporosis. Endocrinology. 1999; 14:4382-9. 153845
Melton LJ 3rd, Atkinson EJ, Cooper C, O'Fallon WM, Riggs BL. Vertebral fractures predict subsequent fractures. Osteoporos Int. 1999; 10(3):214-21. 122668
View PubMed
Khosla S, Melton LJ 3rd, Riggs BL. Osteoporosis: gender differences and similarities. Lupus. 1999; 8(5):393-6. 1010281
View PubMed
Melton LJ 3rd, Atkinson EJ, O'Connor MK, O'Fallon WM, Riggs BL. Bone density and fracture risk in men. J Bone Miner Res. 1998 Dec; 13(12):1915-23. 108606
View PubMed
Emslander HC, Sinaki M, Muhs JM, Chao EY, Wahner HW, Bryant SC, Riggs BL, Eastell R. Bone mass and muscle strength in female college athletes (runners and swimmers). Mayo Clin Proc. 1998 Dec; 73(12):1151-60. 108795
View PubMed
Lufkin EG, Whitaker MD, Nickelsen T, Argueta R, Caplan RH, Knickerbocker RK, Riggs BL. Treatment of established postmenopausal osteoporosis with raloxifene - a randomized. J Bone Miner Res. 1998 Nov; 13(11):1747-1754. 108234
View PubMed
Hofbauer LC, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S. Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines. Biochem Biophys Res Commun. 1998 Sep 29; 250(3):776-81. 108028
View PubMed
Ory SJ, Field CS, Herrmann RR, Zinsmeister AR, Riggs BL. Effects of long-term transdermal administration of estradiol on serum lipids. Mayo Clin Proc. 1998 Aug; 73(8):735-8. 107209
View PubMed
Khosla S, Melton LJ 3rd, Atkinson EJ, O'Fallon WM, Klee GG, Riggs BL. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J Clin Endocrinol Metab. 1998 Jul; 83(7):2266-74. 106361
View PubMed
Heshmati HM, Khosla S, Burritt MF, O'Fallon WM, Riggs BL. A defect in renal calcium conservation may contribute to the pathogenesis of postmenopausal osteoporosis. J Clin Endocrinol Metab. 1998 Jun; 83(6):1916-20. 105705
View PubMed
Riggs BL, Khosla S, Melton LJ. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res. 1998 May; 13(5):763-73. 105246
View PubMed
Roche ME, Anderson MA, Oda RP, Riggs BL, Strausbauch MA, Okazaki R, Wettstein PJ, Landers JP. Capillary electrophoresis of insulin-like growth factors: enhanced ultraviolet detection using dynamically coated capillaries and on-line solid- phase extraction. Anal Biochem. 1998 Apr 10; 258(1):87-95. 104538
View PubMed
Tau KR, Hefferan TE, Waters KM, Robinson JA, Subramaniam M, Riggs BL, Spelsberg TC. Estrogen regulation of a transforming growth factor-beta inducible early gene that inhibits deoxyribonucleic acid synthesis in human osteoblasts. Endocrinology. 1998 Mar; 139(3):1346-53. 103541
View PubMed
Heshmati HM, Riggs BL, Burritt MF, McAlister CA, Wollan PC, Khosla S. Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women. J Clin Endocrinol Metab. 1998 Mar; 83(3):751-6. 103920
View PubMed
Subramaniam M, Hefferan TE, Tau K, Peus D, Pittelkow M, Jalal S, Riggs BL, Roche P, Spelsberg TC. Tissue, cell type, and breast cancer stage-specific expression of a TGF-beta inducible early transcription factor gene. J Cell Biochem. 1998 Feb 1; 68(2):226-36. 102705
View PubMed
Riggs BL, O'Fallon WM, Muhs J, O'Connor MK, Kumar R, Melton LJ 3rd. Long-term effects of calcium supplementation on serum parathyroid hormone level, bone turnover, and bone loss in elderly women. J Bone Miner Res. 1998 Feb; 13(2):168-74. 102966
View PubMed
Hicok KC, Thomas T, Gori F, Rickard DJ, Spelsberg TC, Riggs BL. Development and characterization of conditionally immortalized osteoblast precursor cell lines from human bone marrow stroma. J Bone Miner Res. 1998 Feb; 13(2):205-17. 102967
View PubMed
Rickard DJ, Hofbauer LC, Bonde SK, Gori F, Spelsberg TC, Riggs BL. Bone morphogenetic protein-6 production in human osteoblastic cell lines. Selective regulation by estrogen. J Clin Invest. 1998 Jan 15; 101(2):413-22. 1019038
View PubMed
Kassem M, Okazaki R, Harris SA, Spelsberg TC, Conover CA, Riggs BL. Estrogen effects on insulin-like growth factor gene expression in a human osteoblastic cell line with high levels of estrogen receptor. Calcif Tissue Int. 1998 Jan; 62(1):60-6. 102659
View PubMed
Melton LJ, Egan KS, O'Fallon WM, Riggs BL. Influence of fracture criteria on the outcome of a randomized trial of therapy. Osteoporos Int. 1998; 8(2):184-91. 106390
View PubMed
Hesley RP, Shepard KA, Jenkins DK, Riggs BL. Monitoring estrogen replacement therapy and identifying rapid bone losers with an immunoassay for deoxypyridinoline. Osteoporos Int. 1998; 8(2):159-64. 109514
View PubMed
Melton LJ 3rd, Khosla S, Atkinson EJ, O'Fallon WM, Riggs BL. Relationship of bone turnover to bone density and fractures. J Bone Miner Res. 1997 Jul; 12(7):1083-91. 98943
View PubMed
Robinson JA, Harris SA, Riggs BL, Spelsberg TC. Estrogen regulation of human osteoblastic cell proliferation and differentiation. Endocrinology. 1997 Jul; 138(7):2919-27. 98937
View PubMed
McKane WR, Khosla S, Ristela J, Robins SP, Muhs JM, Riggs BL. Role of estrogen deficiency in pathogenesis of secondary hyperparathyroidism and increased bone resorption in elderly women. Obstet Gynecol Surv. 1997 Jul; 52(7):429-431. 1017392
Khosla S, Atkinson EJ, Melton LJ 3rd, Riggs BL. Effects of age and estrogen status on serum parathyroid hormone levels and biochemical markers of bone turnover in women: a population- based study. J Clin Endocrinol Metab. 1997 May; 82(5):1522-7. 102352
View PubMed
McKane WR, Khosla S, Risteli J, Robins SP, Muhs JM, Riggs BL. Role of estrogen deficiency in pathogenesis of secondary hyperparathyroidism and increased bone resorption in elderly women. Proc Assoc Am Physicians. 1997 Mar; 109(2):174-80. 101887
View PubMed
Conover CA, Lee PD, Riggs BL, Powell DR. Insulin-like growth factor-binding protein-1 expression in cultured human bone cells: regulation by insulin and glucocorticoid. Endocrinology. 1996 Aug; 137(8):3295-301. 97152
View PubMed
Khosla S, Atkinson EJ, Riggs BL, Melton LJ 3rd. Relationship between body composition and bone mass in women. J Bone Miner Res. 1996 Jun; 11(6):857-63. 95824
View PubMed
Clarke BL, Ebeling PR, Jones JD, Wahner HW, O'Fallon WM, Riggs BL, Fitzpatrick LA. Changes in quantitative bone histomorphometry in aging healthy men. J Clin Endocrinol Metab. 1996 Jun; 81(6):2264-70. 95427
View PubMed
Cooper C, Atkinson EJ, Hensrud DD, Wahner HW, O'Fallon WM, Riggs BL, Melton LJ. Dietary protein intake and bone mass in women. Calcif Tissue Int. 1996 May; 58(5):320-5. 95198
View PubMed
McKane WR, Khosla S, Egan KS, Robins SP, Burritt MF, Riggs BL. Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption. J Clin Endocrinol Metab. 1996 May; 81(5):1699-703. 96151
View PubMed
Kassem M, Okazaki R, Deleon D, Harris SA, Robinson JA, Spelsberg TC, Conover CA, Riggs BL. Potential mechanism of estrogen-mediated decrease in bone formation: estrogen increases production of inhibitory insulin-like growth factor- binding protein-lC. Proc Assoc Am Physicians. 1996 Mar; 108(2):155-64. 95919
View PubMed
Riggs BL, Melton LJ, Ofallon WM. Drug therapy for vertebral fractures in osteoporosis: evidence that decreases in bone turnover and increases in bone mass both determine antifracture efficacy. Bone. 1996 Mar; 18(3 Suppl S):S 197-S 201. 95970
View PubMed
Rickard DJ, Kassem M, Hefferan TE, Sarkar G, Spelsberg TC, Riggs BL. Isolation and characterization of osteoblast precursor cells from human bone marrow. J Bone Miner Res. 1996 Mar; 11(3):312-24. 95428
View PubMed
Robinson JA, Riggs BL, Spelsberg TC, Oursler MJ. Osteoclasts and transforming growth factor-beta: estrogen-mediated isoform-specific regulation of production. Endocrinology. 1996 Feb; 137(2):615-21. 95236
View PubMed
Kassem M, Khosla S, Spelsberg TC, Riggs BL. Cytokine production in the bone marrow microenvironment: failure to demonstrate estrogen regulation in early postmenopausal women. J Clin Endocrinol Metab. 1996 Feb; 81(2):513-8. 95559
View PubMed
Kassem M, Harris SA, Spelsberg TC, Riggs BL. Estrogen inhibits interleukin-6 production and gene expression in a human osteoblastic cell line with high levels of estrogen receptors. J Bone Miner Res. 1996 Feb; 11(2):193-9. 95635
View PubMed
McKane WR, Khosla S, Egan KS, Robins S, Burritt MF, Riggs BL. A high calcium intake reverses the secondary hyperparathyroidism and increased bone resorption of elderly women J Clinical Endocrinol Metab. 1996; 81:1699-703. 153824
Cooper C, Kotowicz M, Atkinson EJ, O'Fallon WM, Riggs BL, Melton LJ III. Risk of limb fractures among men and women with vertebral fractures. Int Congr Ser. 1996; 1118:101-104. 98444
Riggs BL, Spelsberg TC. Mechanisms of estrogen action on bone cells. Osteoporosis. 1996; 1118: 241-50. 98445
Subramaniam M, Harris SA, Oursler MJ, Rasmussen K, Riggs BL, Spelsberg TC. Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts. Nucleic Acids Res. 1995 Dec 11; 23(23):4907-12. 91071
View PubMed
McKane WR, Khosla S, Burritt MF, Kao PC, Wilson DM, Ory SJ, Riggs BL. Mechanism of renal calcium conservation with estrogen replacement therapy in women in early postmenopause--a clinical research center study. J Clin Endocrinol Metab. 1995 Dec; 80(12):3458-64. 91143
View PubMed
Riggs BL, Melton LJ 3rd. The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone. 1995 Nov; 17(5 Suppl):505S-511S. 91200
View PubMed
Ledger GA, Burritt MF, Kao PC, O'Fallon WM, Riggs BL, Khosla S. Role of parathyroid hormone in mediating nocturnal and age-related increases in bone resorption. J Clin Endocrinol Metab. 1995 Nov; 80(11):3304-10. 91258
View PubMed
Harris SA, Tau KR, Enger RJ, Toft DO, Riggs BL, Spelsberg TC. Estrogen response in the hFOB 1.19 human fetal osteoblastic cell line stably transfected with the human estrogen receptor gene. J Cell Biochem. 1995 Oct; 59(2):193-201. 94087
View PubMed
Khosla S, Riggs BL. Treatment options for osteoporosis. Mayo Clin Proc. 1995 Oct; 70(10):978-82. 93500
View PubMed
Riggs BL, Khosla S. Role of biochemical markers in assessment of osteoporosis. Acta Orthop Scand Suppl. 1995 Oct; 266:14-8. 91037
View PubMed
Clarke BL, Muhs JM, O'Connell MJ, McCarthy JT, O'Fallon WM, Riggs BL. Assessment of bone resorption in metabolic bone disorders using a new enzyme immunoassay for urinary free pyridinoline: comparison with standard methods of assessment of bone formation. Endocr Pract. 1995 Jul-Aug; 1(4):248-56. 94685
Janes CH, Dickson ER, Okazaki R, Bonde S, McDonagh AF, Riggs BL. Role of hyperbilirubinemia in the impairment of osteoblast proliferation associated with cholestatic jaundice. J Clin Invest. 1995 Jun; 95(6):2581-6. 92801
View PubMed
Riggs BL, Nguyen TV, Melton LJ 3rd, Morrison NA, O'Fallon WM, Kelly PJ, Egan KS, Sambrook PN, Muhs JM, Eisman JA. The contribution of vitamin D receptor gene alleles to the determination of bone mineral density in normal and osteoporotic women. J Bone Miner Res. 1995 Jun; 10(6):991-6. 93539
View PubMed
Okazaki R, Conover CA, Harris SA, Spelsberg TC, Riggs BL. Normal human osteoblast-like cells consistently express genes for insulin-like growth factors I and II but transformed human osteoblast cell lines do not. Journal of Bone & Mineral Research. 1995 May; 10(5):788-95. 92357
View PubMed
Schutze N, Oursler MJ, Nolan J, Riggs BL, Spelsberg TC. Zeolite A inhibits osteoclast-mediated bone resorption in vitro. J Cell Biochem. 1995 May; 58(1):39-46. 92658
View PubMed
Durham SK, Riggs BL, Harris SA, Conover CA. Alterations in insulin-like growth factor (IGF)-dependent IGF-binding protein-4 proteolysis in transformed osteoblastic cells. Endocrinology. 1995 Apr; 136(4):1374-80. 92247
View PubMed
Lundy MW, Stauffer M, Wergedal JE, Baylink DJ, Featherstone JD, Hodgson SF, Riggs BL. Histomorphometric analysis of iliac crest bone biopsies in placebo-treated versus fluoride-treated subjects. Osteoporos Int. 1995 Mar; 5(2):115-29. 92463
View PubMed
Okazaki R, Durham SK, Riggs BL, Conover CA. Transforming growth factor-beta and forskolin increase all classes of insulin-like growth factor-I transcripts in normal human osteoblast-like cells. Biochemical & Biophysical Research Communications. 1995 Feb 27; 207(3):963-70. 92072
View PubMed
Harris SA, Enger RJ, Riggs BL, Spelsberg TC. Development and characterization of a conditionally immortalized human fetal osteoblastic cell line. J Bone Miner Res. 1995 Feb; 10(2):178-86. 91770
View PubMed
Bodine PV, Riggs BL, Spelsberg TC. Regulation of c-fos expression and TGF-beta production by gonadal and adrenal androgens in normal human osteoblastic cells. Journal of Steroid Biochemistry & Molecular Biology. 1995 Feb; 52(2):149-58. 92549
View PubMed
Durham SK, De Leon DD, Okazaki R, Riggs BL, Conover CA. Regulation of insulin-like growth factor (IGF)-binding protein-4 availability in normal human osteoblast-like cells: role of endogenous IGFs. Journal of Clinical Endocrinology & Metabolism. 1995 Jan; 80(1):104-10. 91859
View PubMed
Subramaniam M, Oursler MJ, Rasmussen K, Riggs BL, Spelsberg TC. TGF-beta regulation of nuclear proto-oncogenes and TGF-beta gene expression in normal human osteoblast-like cells. J Cell Biochem. 1995 Jan; 57(1):52-61. 92184
View PubMed
Spelsberg TC, Harris SA, Riggs BL. Immortalized osteoblast cell systems (new human fetal osteoblast systems). Calcif Tissue Int. 1995; 56(Suppl 1):S18-21. 91764
View PubMed
Tomlinson AJ, Benson LM, Oda RP, Braddock WD, Riggs BL, Katzmann JA, Naylor S. Novel modifications, clinical applications of preconcentration-capillary electrophoresis-mass spectrometry. J Cap Elect. 1995; 2:97-104. 1208278
Durham SK, Riggs BL, Conover CA. The insulin-like growth factor-binding protein-4 (IGFBP-4)-IGFBP-4 protease system in normal human osteoblast-like cells: regulation by transforming growth factor-beta. Journal of Clinical Endocrinology & Metabolism. 1994 Dec; 79(6):1752-8. 90311
View PubMed
Ebeling PR, Yergey AL, Vieira NE, Burritt MF, O'Fallon WM, Kumar R, Riggs BL. Influence of age on effects of endogenous 1,25-dihydroxyvitamin D on calcium absorption in normal women. Calcif Tissue Int. 1994 Nov; 55(5):330-4. 90224
View PubMed
Lufkin EG, Argueta R, Whitaker MD, Cameron AL, Wong VH, Egan KS, O'Fallon WM, Riggs BL. Pamidronate: an unrecognized problem in gastrointestinal tolerability. Osteoporos Int. 1994 Nov; 4(6):320-2. 90814
View PubMed
Khosla S, Peterson JM, Egan K, Jones JD, Riggs BL. Circulating cytokine levels in osteoporotic and normal women. J Clin Endocrinol Metab. 1994 Sep; 79(3):707-11. 88926
View PubMed
Beard CM, Lane AW, O'Fallon WM, Riggs BL, Melton LJ. Comparison of respondents and nonrespondents in an osteoporosis study. Ann Epidemiol. 1994 Sep; 4(5):398-403. 90437
View PubMed
Valimaki MJ, Tahtela R, Jones JD, Peterson JM, Riggs BL Jr. Bone resorption in healthy and osteoporotic postmenopausal women--comparison markers for serum carboxy-terminal telopeptide of type 1 collagen and urinary pyridinium cross-links. European Journal of Endocrinology. 1994 Sep; 131:258-262. 90155
View PubMed
McKane WR, Khosla S, Peterson JM, Egan K, Riggs BL. Circulating levels of cytokines that modulate bone resorption: effects of age and menopause in women. J Bone Miner Res. 1994 Aug; 9(8):1313-8. 89011
View PubMed
Ledger GA, Burritt MF, Kao PC, O'Fallon WM, Riggs BL, Khosla S. Abnormalities of parathyroid hormone secretion in elderly women that are reversible by short term therapy with 1,25-dihydroxyvitamin D3. J Clin Endocrinol Metab. 1994 Jul; 79(1):211-6. 88351
View PubMed
Oursler MJ, Pederson L, Fitzpatrick L, Riggs BL, Spelsberg T. Human giant cell tumors of the bone (osteoclastomas) are estrogen target cells. Proc Natl Acad Sci U S A. 1994 Jun 7; 91(12):5227-31. 88504
View PubMed
Roapena L, Zreik T, Harada N, Spelsberg TC, Riggs BL Jr, Naftolin F. Human osteoblast-like cells express aromatase immunoreactivity. Menopause. 1994 Summer; 1:73-77. 90380
Turner RT, Riggs BL, Spelsberg TC. Skeletal effects of estrogen. Endocr Rev. 1994 Jun; 15(3):275-300. 88706
View PubMed
Spotila LD, Colige A, Sereda L, Constantinou-Deltas CD, Whyte MP, Riggs BL, Shaker JL, Spector TD, Hume E, Olsen N. Mutation analysis of coding sequences for type I procollagen in individuals with low bone density. J Bone Miner Res. 1994 Jun; 9(6):923-32. 1314005
View PubMed
Kotowicz MA, Melton LJ, Cooper C, Atkinson EJ, O'Fallon WM, Riggs BL. Risk of hip fracture in women with vertebral fracture. J Bone Miner Res. 1994 May; 9(5):599-605. 87737
View PubMed
Riggs BL, O'Fallon WM, Lane A, Hodgson SF, Wahner HW, Muhs J, Chao E, Melton LJ 3rd. Clinical trial of fluoride therapy in postmenopausal osteoporotic women: extended observations and additional analysis. J Bone Miner Res. 1994 Feb; 9(2):265-75. 87068
View PubMed
Ingram RT, Bonde SK, Riggs BL, Fitzpatrick LA. Effects of transforming growth factor beta (TGF beta) and 1,25 dihydroxyvitamin D3 on the function, cytochemistry and morphology of normal human osteoblast-like cells. Differentiation. 1994 Jan; 55(2):153-63. 87364
View PubMed
Durham SK, Kiefer MC, Riggs BL, Conover CA. Regulation of insulin-like growth factor binding protein 4 by a specific insulin-like growth factor binding protein 4 proteinase in normal human osteoblast-like cells: implications in bone cell physiology. J Bone Miner Res. 1994 Jan; 9(1):111-7. 87220
View PubMed
Okazaki R, Riggs BL Jr, Conover CA. Glucocortoid regulation of insulin-like growth factor-binding protein expression in normal human osteoblast-like cells. Endocrinology. 1994 Jan; 134:126-132. 86865
View PubMed
McKane WR, Khosla S, Peterson JM, Egan K, Riggs BL. Assessment of circulating levels of cytokines modulating bone resorption: effects of age and menopause in women J Bone Mineral Res. 1994; 9:1313-8. 153559
Riggs BL Jr. Formation-stimulating regimens other than sodium fluoride. Am J Med. 1993 Nov 30; 95:5A-62S - 5A-68S. 84967
View PubMed
Ebeling PR, Jones JD, O'Fallon WM, Janes CH, Riggs BL. Short-term effects of recombinant human insulin-like growth factor I on bone turnover in normal women. J Clin Endocrinol Metab. 1993 Nov; 77(5):1384-7. 84597
View PubMed
Hodgson SF, Dickson ER, Eastell R, Eriksen EF, Bryant SC, Riggs BL. Rates of cancellous bone remodeling and turnover in osteopenia associated with primary biliary cirrhosis. Bone. 1993 Nov-Dec; 14(6):819-27. 84989
View PubMed
Oursler MJ, Riggs BL, Spelsberg TC. Glucocorticoid-induced activation of latent transforming growth factor-beta by normal human osteoblast-like cells. Endocrinology. 1993 Nov; 133(5):2187-96. 85350
View PubMed
Melton LJ 3rd, Atkinson EJ, O'Fallon WM, Wahner HW, Riggs BL. Long-term fracture prediction by bone mineral assessed at different skeletal sites. J Bone Miner Res. 1993 Oct; 8(10):1227-33. 84753
View PubMed
Eastell R, Robins SP, Colwell T, Assiri AM, Riggs BL, Russell RG. Evaluation of bone turnover in type I osteoporosis using biochemical markers specific for both bone formation and bone resorption. Osteoporos Int. 1993 Sep; 3(5):255-60. 84456
View PubMed
Oursler MJ, Landers JP, Riggs BL, Spelsberg TC. Oestrogen effects on osteoblasts and osteoclasts. Ann Med. 1993 Aug; 25(4):361-71. 84743
View PubMed
Kao PC, Riggs BL, Schryver PG. Development and evaluation of an osteocalcin chemiluminoimmunoassay. Clin Chem. 1993 Jul; 39(7):1369-74. 2210694
View PubMed
Melton LJ 3rd, Lane AW, Cooper C, Eastell R, O'Fallon WM, Riggs BL. Prevalence and incidence of vertebral deformities. Osteoporos Int. 1993 May; 3(3):113-9. 85804
View PubMed
Melton LJ 3rd, Bryant SC, Wahner HW, O'Fallon WM, Malkasian GD, Judd HL, Riggs BL. Influence of breastfeeding and other reproductive factors on bone mass later in life. Osteoporos Int. 1993 Mar; 3(2):76-83. 83450
View PubMed
Lufkin EG, Riggs BL Jr. Author's reply. Ann Intern Med. 1993 Jan 15; 118:156. 1030545
Field CS, Ory SJ, Wahner HW, Herrmann RR, Judd HL, Riggs BL. Preventive effects of transdermal 17 beta-estradiol on osteoporotic changes after surgical menopause: a two-year placebo-controlled trial. American Journal of Obstetrics & Gynecology. 1993 Jan; 168(1 Pt 1):114-21. 1313894
View PubMed
Oursler MJ, Riggs BL, Fitzpatrick L, Spelsberg TC. Estrogen action on bone cells: the osteoclasts. Fourth International Symposium on Osteoporosis. 1993; 386-91. 1701557
Subramaniam M, Colvard D, Keeting PE, Rasmussen K, Riggs BL, Spelsberg TC. Glucocorticoid regulation of alkaline phosphatase, osteocalcin, and proto-oncogenes in normal human osteoblast-like cells. J Cell Biochem. 1992 Dec; 50(4):411-24. 104130
View PubMed
Frye MA, Melton LJ 3rd, Bryant SC, Fitzpatrick LA, Wahner HW, Schwartz RS, Riggs BL. Osteoporosis and calcification of the aorta. Bone Miner. 1992 Nov; 19(2):185-94. 1313812
View PubMed
Ebeling PR, Peterson JM, Riggs BL. Utility of type I procollagen propeptide assays for assessing abnormalities in metabolic bone diseases. J Bone Miner Res. 1992 Nov; 7(11):1243-50. 81056
View PubMed
Keeting PE, Oursler MJ, Wiegand KE, Bonde SK, Spelsberg TC, Riggs BL. Zeolite A increases proliferation, differentiation, and transforming growth factor beta production in normal adult human osteoblast-like cells in vitro. J Bone Miner Res. 1992 Nov; 7(11):1281-9. 81057
View PubMed
Ebeling PR, Jones JD, Burritt MF, Duerson CR, Lane AW, Hassager C, Kumar R, Riggs BL. Skeletal responsiveness to endogenous parathyroid hormone in postmenopausal osteoporosis. J Clin Endocrinol Metab. 1992 Oct; 75(4):1033-8. 80701
View PubMed
Riggs BL, Melton LJ 3rd. The prevention and treatment of osteoporosis. N Engl J Med. 1992 Aug 27; 327(9):620-7. 80451
View PubMed
Lufkin EG, Wahner HW, O'Fallon WM, Hodgson SF, Kotowicz MA, Lane AW, Judd HL, Caplan RH, Riggs BL. Treatment of postmenopausal osteoporosis with transdermal estrogen. Ann Intern Med. 1992 Jul 1; 117(1):1-9. 80259
View PubMed
Hassager C, Fitzpatrick LA, Spencer EM, Riggs BL, Conover CA. Basal and regulated secretion of insulin-like growth factor binding proteins in osteoblast-like cells is cell line specific. Journal of Clinical Endocrinology & Metabolism. 1992 Jul; 75(1):228-33. 81599
View PubMed
Ebeling PR, Sandgren ME, DiMagno EP, Lane AW, DeLuca HF, Riggs BL. Evidence of an age-related decrease in intestinal responsiveness to vitamin D: relationship between serum 1,25-dihydroxyvitamin D3 and intestinal vitamin D receptor concentrations in normal women. J Clin Endocrinol Metab. 1992 Jul; 75(1):176-82. 82519
View PubMed
Eastell R, Vieira NE, Yergey AL, Wahner HW, Silverstein MN, Kumar R, Riggs BL. Pernicious anaemia as a risk factor for osteoporosis. Clin Sci (Lond) 1992 Jun; 82(6):681-5. 82024
View PubMed
Riggs BL Jr. State of the art management of osteoporosis. The Practice of Internal Medicine-1992 1992 May 11-15; 87-9. 1027691
Chaudhary LR, Spelsberg TC, Riggs BL. Production of various cytokines by normal human osteoblast-like cells in response to interleukin-1 beta and tumor necrosis factor-alpha: lack of regulation by 17 beta-estradiol. Endocrinology. 1992 May; 130(5):2528-34. 104129
View PubMed
Cooper C, Atkinson EJ, Wahner HW, O'Fallon WM, Riggs BL, Judd HL, Melton LJ 3rd. Is caffeine consumption a risk factor for osteoporosis? J Bone Miner Res. 1992 Apr; 7(4):465-71. 79662
View PubMed
Eastell R, Calvo MS, Burritt MF, Offord KP, Russell RG, Riggs BL. Abnormalities in circadian patterns of bone resorption and renal calcium conservation in type I osteoporosis. J Clin Endocrinol Metab. 1992 Mar; 74(3):487-94. 81466
View PubMed
Keeting PE, Scott RE, Colvard DS, Anderson MA, Oursler MJ, Spelsberg TC, Riggs BL Jr. Development and characterization of a rapidly proliferating, well-differentiated cell line derived from adult human osteoblast-like cells transfected with SV40 large T antigen. J Bone Miner Res. 1992 Feb; 7:127-36. 79520
View PubMed
Osdoby P, Oursler MJ, Pyfferoen J, Riggs BL Jr, Spelsberg TC. The regulation of osteoclast activity. Int Congr Ser. 1992; 1002:339-46. 81444
Eastell R, Simmons PS, Colwell T, Assiri AMA, Burritt MF, Russell RGG, Riggs BL Jr. Nyctohemeral changes in bone turnover assessed by serum bone Gla-protein concentration and urinary deoxypyridinoline excretion: effect of growth aging. Clin Sci (Lond) 1992; 8:375-382. 81467
Melton LJ, Chrischilles EA, Cooper C, Lane AW, Riggs BL Jr. How many women have osteoporosis? J Bone Miner Res. 1992; 7:1005-1010. 81695
View PubMed
Kang AH, Krane SM, LeRoy EC, Riggs BL, Goldberg VM. Scientific workshop on the biology and pathology of acquired connective tissue diseases Arthritis Rheum. 1992; 35:1289-95. 155680
View PubMed
Oursler MJ, Cortese C, Keeting P, Anderson MA, Bonde SK, Riggs BL, Spelsberg TC. Modulation of transforming growth factor-beta production in normal human osteoblast-like cells by 17 beta-estradiol and parathyroid hormone. Endocrinology. 1991 Dec; 129(6):3313-20. 104133
View PubMed
Oursler MJ, Osdoby P, Pyfferoen J, Riggs BL, Spelsberg TC. Avian osteoclasts as estrogen target cells. Proc Natl Acad Sci U S A. 1991 Aug 1; 88(15):6613-7. 76940
View PubMed
Eastell R, Dickson ER, Hodgson SF, Wiesner RH, Porayko MK, Wahner HW, Cedel SL, Riggs BL, Krom RA. Rates of vertebral bone loss before and after liver transplantation in women with primary biliary cirrhosis. Hepatology. 1991 Aug; 14(2):296-300. 76950
View PubMed
Keeting PE, Rifas L, Harris SA, Colvard DS, Spelsberg TC, Peck WA, Riggs BL Jr. Evidence for interleukin-1B production by cultured normal human osteoblast-like cells. J Bone Miner Res. 1991 Aug; 6:827-833. 76963
View PubMed
Ebeling PR, Butler PC, Eastell R, Rizza RA, Riggs BL. The nocturnal increase in growth hormone is not the cause of the nocturnal increase in serum osteocalcin. J Clin Endocrinol Metab. 1991 Aug; 73(2):368-72. 78355
View PubMed
Gonchoroff DG, Branum EL, Cedel SL, Riggs BL, O'Brien JF. Clinical evaluation of high-performance affinity chromatography for the separation of bone and liver alkaline phosphatase isoenzymes. Clin Chim Acta. 1991 May 31; 199(1):43-50. 76762
View PubMed
Hassager C, Bonde SK, Anderson MA, Rink H, Spelsberg TC, Riggs BL. Procalcitonin NH2-terminal cleavage peptide has no mitogenic effect on normal human osteoblast-like cells. J Bone Miner Res. 1991 May; 6(5):489-93. 76708
View PubMed
Eastell R, Cedel SL, Wahner HW, Riggs BL, Melton LJ 3rd. Classification of vertebral fractures. J Bone Miner Res. 1991 Mar; 6(3):207-15. 76241
View PubMed
Keeting PE, Scott RE, Colvard DS, Han IK, Spelsberg TC, Riggs BL. Lack of a direct effect of estrogen on proliferation and differentiation of normal human osteoblast-like cells. J Bone Miner Res. 1991 Mar; 6(3):297-304. 76242
View PubMed
Eastell R, Yergey AL, Vieira NE, Cedel SL, Kumar R, Riggs BL. Interrelationship among vitamin D metabolism, true calcium absorption, parathyroid function, and age in women: evidence of an age-related intestinal resistance to 1,25-dihydroxyvitamin D action. J Bone Miner Res. 1991 Feb; 6(2):125-32. 78681
View PubMed
Riggs BL. Overview of osteoporosis. West J Med. 1991 Jan; 154(1):63-77. 75965
View PubMed
Spotila LD, Constantinou CD, Sereda L, Ganguly A, Riggs BL, Prockop DJ. Mutation in a gene for type I procollagen (COL1A2) in a woman with postmenopausal osteoporosis: Eveidence for phenotypic and genotypic overlap with mild osteogenesis imperfecta. Proc Natl Acad Sci USA. 1991; 88:5423-7. 155676
View PubMed
Riggs BL. Treatment of osteoporosis with sodium fluoride or parathyroid hormone Am J Med. 1991; 91(5B):37S-41S. 155677
View PubMed
Eastell R, Mosekilde L, Hodgson SF, Riggs BL. Proportion of human vertebral body bone that is cancellous. J Bone Miner Res. 1990 Dec; 5(12):1237-41. 74204
View PubMed
Kotowicz MA, Hall S, Hunder GG, Cedel SL, Mann KG, Riggs BL. Relationship of glucocorticoid dosage to serum bone Gla-protein concentration in patients with rheumatologic disorders. Arthritis Rheum. 1990 Oct; 33(10):1487-92. 73601
View PubMed
Kotowicz MA, Klee GG, Kao PC, O'Fallon WM, Hodgson SF, Cedel SL, Eriksen EF, Gonchoroff DG, Judd HL, Riggs BL. Relationship between serum intact parathyroid hormone concentrations and bone remodeling in type I osteoporosis: evidence that skeletal sensitivity is increased. Osteoporos Int. 1990 Oct; 1(1):14-22. 1313587
View PubMed
Beard CM, Melton LJ 3rd, Cedel SL, Richelson LS, Riggs BL. Ascertainment of risk factors for osteoporosis: comparison of interview data with medical record review. J Bone Miner Res. 1990 Jul; 5(7):691-9. 73096
View PubMed
Nelson D, Peterson E, Tilley B, O'Fallon WM, Chao E, Riggs BL, Kleerekoper M. Measurement of vertebral area on spine x-rays in osteoporosis: reliability of digitizing techniques. J Bone Miner Res. 1990 Jul; 5(7):707-16. 73097
View PubMed
Tracy RP, Andrianorivo A, Riggs BL, Mann KG. Comparison of monoclonal and polyclonal antibody-based immunoassays for osteocalcin: a study of sources of variation in assay results. J Bone Miner Res. 1990 May; 5(5):451-61. 72622
View PubMed
Riggs BL, Melton LJ 3rd. Clinical review 8: Clinical heterogeneity of involutional osteoporosis: implications for preventive therapy. Journal of Clinical Endocrinology & Metabolism. 1990 May; 70(5):1229-32. 72576
View PubMed
Kotowicz MA, Melton LJ 3rd, Cedel SL, O'Fallon WM, Riggs BL. Effect of age on variables relating to calcium and phosphorus metabolism in women. J Bone Miner Res. 1990 Apr; 5(4):345-52. 72515
View PubMed
Riggs BL. Clinical update on calcitriol: introduction. Metabolism: Clinical & Experimental. 1990 Apr; 39(4 Suppl 1):1-2. 72403
View PubMed
Gallagher JC, Riggs BL Jr. Action of 1,25-dihydroxyvitamin D3 on calcium balance and a bone turnover and its effect on vertebral fracture rate. Metabolism. 1990 Apr; 39(Suppl 1):30-34. 72404
View PubMed
Riggs BL, Hodgson SF, O'Fallon WM, Chao EY, Wahner HW, Muhs JM, Cedel SL, Melton LJ 3rd. Effect of fluoride treatment on the fracture rate in postmenopausal women with osteoporosis. N Engl J Med. 1990 Mar 22; 322(12):802-9. 72343
View PubMed
Tsai KS, Ebeling PR, Riggs BL Jr. Bone responsiveness to parathyroid hormone in normal and osteoporotic postmenopausal women. J Clin Endocrinol Metab. 1989 Nov; 69:1024-1027. 70046
View PubMed
Eastell R, Vieira NE, Yergey AL, Riggs BL. One-day test using stable isotopes to measure true fractional calcium absorption. J Bone Miner Res. 1989 Aug; 4(4):463-8. 69694
View PubMed
Eastell R, Riggs BL, Wahner HW, O'Fallon WM, Amadio PC, Melton LJ 3rd. Colles' fracture and bone density of the ultradistal radius. J Bone Miner Res. 1989 Aug; 4(4):607-13. 69695
View PubMed
Gallagher JC, Riggs BL, Recker RR, Goldgar D. The effect of calcitriol on patients with postmenopausal osteoporosis with special reference to fracture frequency. Experimental Biology & Medicine. 1989 Jul; 191(3):287-92. 1313445
View PubMed
Melton LJ 3rd, Kan SH, Frye MA, Wahner HW, O'Fallon WM, Riggs BL. Epidemiology of vertebral fractures in women. Am J Epidemiol. 1989 May; 129(5):1000-11. 69042
View PubMed
Eastell R, Dewanjee MK, Riggs BL. Comparison of polyethylene glycol and chromium-51 chloride as nonabsorbable stool markers in calcium balance studies. Bone Miner. 1989 Apr; 6(1):95-105. 69091
View PubMed
Riggs BL, Spelsberg TC. Mechanisms of estrogen action on bone. Postgrad Med. 1989 Apr; (Spec. No.):13-4, dicussion 33-43. 104136
Colvard DS, Eriksen EF, Keeting PE, Wilson EM, Lubahn DB, French FS, Riggs BL, Spelsberg TC. Identification of androgen receptors in normal human osteoblast-like cells. Proc Natl Acad Sci U S A. 1989 Feb; 86(3):854-7. 104135
View PubMed
Eastell R, Wahner HW, O'Fallon WM, Amadio PC, Melton LJ 3rd, Riggs BL. Unequal decrease in bone density of lumbar spine and ultradistal radius in Colles' and vertebral fracture syndromes. J Clin Invest. 1989 Jan; 83(1):168-74. 1313476
View PubMed
Colvard D, Spelsberg T, Eriksen E, Keeting P, Riggs BL. Evidence of steroid receptors in human osteoblast-like cells. Connect Tissue Res. 1989; 20(1-4):33-40. 70139
View PubMed
Borke JL, Eriksen EF, Minami J, Keeting P, Mann KG, Penniston JT, Riggs BL, Kumar R. Epitopes of the human erythrocyte Ca2+-Mg2+ ATPase pump in human osteoblast-like cell plasma membranes. J Clin Endocrinol Metab. 1988 Dec; 67(6):1299-304. 66823
View PubMed
Wahner HW, Dunn WL, Brown ML, Morin RL, Riggs BL. Comparison of dual-energy x-ray absorptiometry and dual photon absorptiometry for bone mineral measurements of the lumbar spine. Mayo Clin Proc. 1988 Nov; 63(11):1075-84. 66691
View PubMed
Eastell R, Delmas PD, Hodgson SF, Eriksen EF, Mann KG, Riggs BL. Bone formation rate in older normal women: concurrent assessment with bone histomorphometry, calcium kinetics, and biochemical markers. J Clin Endocrinol Metab. 1988 Oct; 67(4):741-8. 66200
View PubMed
Eastell R, Riggs BL. Diagnostic evaluation of osteoporosis. Endocrinology & Metabolism Clinics of North America. 1988 Sep; 17(3):547-71. 66063
View PubMed
Eriksen EF, Colvard DS, Berg NJ, Graham ML, Mann KG, Spelsberg TC, Riggs BL. Evidence of estrogen receptors in normal human osteoblast-like cells. Science. 1988 Jul 1; 241(4861):84-6. 65709
View PubMed
Duda RJ Jr, O'Brien JF, Katzmann JA, Peterson JM, Mann KG, Riggs BL. Concurrent assays of circulating bone Gla-protein and bone alkaline phosphatase: effects of sex, age, and metabolic bone disease. J Clin Endocrinol Metab. 1988 May; 66(5):951-7. 65257
View PubMed
Peck WA, Riggs BL, Bell NH, Wallace RB, Johnston CC Jr, Gordon SL, Shulman LE. Research directions in osteoporosis. Am J Med. 1988 Feb; 84(2):275-82. 64791
View PubMed
Melton LJ 3rd, Kan SH, Wahner HW, Riggs BL. Lifetime fracture risk: an approach to hip fracture risk assessment based on bone mineral density and age. J Clin Epidemiol. 1988; 41(10):985-94. 66989
View PubMed
Riggs BL Jr, Melton LJ. Osteoporosis and age-related fracture syndromes. Ciba Found Symp. 1988; 134:129-42. 65158
View PubMed
Tracy RP, Shull S, Riggs BL, Mann KG. The osteonectin family of proteins. Int J Biochem. 1988; 20(7):653-60. 65957
View PubMed
Eastell R, Riggs BL. New approaches to the treatment of osteoporosis. Clin Obstet Gynecol. 1987 Dec; 30(4):860-70. 155314
View PubMed
Forero MS, Klein RF, Nissenson RA, Nelson K, Heath H 3rd, Arnaud CD, Riggs BL. Effect of age on circulating immunoreactive and bioactive parathyroid hormone levels in women. J Bone Miner Res. 1987 Oct; 2(5):363-6. 62897
View PubMed
Riggs BL, Wahner HW, Melton LJ 3rd, Richelson LS, Judd HL, O'Fallon WM. Dietary calcium intake and rates of bone loss in women. J Clin Invest. 1987 Oct; 80(4):979-82. 62924
View PubMed
Eastell R, Riggs BL, Kumar R. A primed-infusion technique for rapid estimation of the metabolic clearance rate of 1,25(OH)2D3. Am J Physiol. 1987 Sep; 253(3 Pt 1):E246-50. 63003
View PubMed
Melton LJ 3rd, O'Fallon WM, Riggs BL. Secular trends in the incidence of hip fractures. Calcif Tissue Int. 1987 Aug; 41(2):57-64. 62458
View PubMed
Tsai KS, Wahner HW, Offord KP, Melton LJ 3rd, Kumar R, Riggs BL. Effect of aging on vitamin D stores and bone density in women. Calcif Tissue Int. 1987 May; 40(5):241-3. 61757
View PubMed
Riggs BL. Pathogenesis of osteoporosis. American Journal of Obstetrics & Gynecology. 1987 May; 156(5):1342-6. 62190
View PubMed
Duda RJ, Kumar R, Nelson KI, Zinsmeister AR, Mann KG, Riggs BL. 1,25-Dihydroxyvitamin D stimulation test for osteoblast function in normal and osteoporotic postmenopausal women. J Clin Invest. 1987 Apr; 79(4):1249-53. 61440
View PubMed
Riggs BL, Baylink DJ, Kleerekoper M, Lane JM, Melton LJ 3rd, Meunier PJ. Incidence of hip fractures in osteoporotic women treated with sodium fluoride. J Bone Miner Res. 1987 Apr; 2(2):123-6. 61690
View PubMed
Eastell R, Riggs BL. Treatment of osteoporosis. Obstetrics & Gynecology Clinics of North America. 1987 Mar; 14(1):77-88. 61777
View PubMed
Eriksen EF, Riggs BL Jr, Kumar R. Osteoporosis: recent concepts and approaches to treatment. New Developments in Medicine. 1987; 2:11-23. 64437
Utz JP, Melton LJ 3rd, Kan SH, Riggs BL. Risk of osteoporotic fractures in women with breast cancer: a population-based cohort study. J Chronic Dis. 1987; 40(2):105-13. 61308
View PubMed
Eastell R, Riggs BL. Calcium homeostasis and osteoporosis. Endocrinol Metab Clin. 1987; 16:829-42. 155313
Riggs BL Jr. Questions and answers: mild postmenopausal serum calcium elevation. JAMA. 1986 Dec 12; 256:3156-3157. 1053465
Riggs BL, Tsai KS, Mann KG. Effect of acute increases in bone matrix degradation on circulating levels of bone-Gla protein. J Bone Miner Res. 1986 Dec; 1(6):539-42. 61123
View PubMed
Stenner DD, Tracy RP, Riggs BL, Mann KG. Human platelets contain and secrete osteonectin, a major protein of mineralized bone. Proc Natl Acad Sci U S A. 1986 Sep; 83(18):6892-6. 59143
View PubMed
Melton LJ 3rd, Wahner HW, Richelson LS, O'Fallon WM, Riggs BL. Osteoporosis and the risk of hip fracture. Am J Epidemiol. 1986 Aug; 124(2):254-61. 58776
View PubMed
Riggs BL, Wahner HW, Melton LJ 3rd, Richelson LS, Judd HL, Offord KP. Rates of bone loss in the appendicular and axial skeletons of women. Evidence of substantial vertebral bone loss before menopause. J Clin Invest. 1986 May; 77(5):1487-91. 58273
View PubMed
O'Duffy JD, Wahner HW, O'Fallon WM, Johnson KA, Muhs JM, Beabout JW, Hodgson SF, Riggs BL. Mechanism of acute lower extremity pain syndrome in fluoride-treated osteoporotic patients. Am J Med. 1986 Apr; 80(4):561-6. 58176
View PubMed
Tremaine WJ, Newcomer AD, Riggs BL, McGill DB. Calcium absorption from milk in lactase-deficient and lactase-sufficient adults. Dig Dis Sci. 1986 Apr; 31(4):376-8. 58204
View PubMed
Romberg RW, Werness PG, Riggs BL, Mann KG. Inhibition of hydroxyapatite crystal growth by bone-specific and other calcium-binding proteins. Biochemistry. 1986 Mar 11; 25(5):1176-80. 58105
View PubMed
Epstein S, Bryce G, Hinman JW, Miller ON, Riggs BL, Hui SL, Johnston CC Jr. The influence of age on bone mineral regulating hormones. Bone. 1986; 7(6):421-5. 1313091
View PubMed
Riggs BL Jr, Melton LJ. Medical progress: involutional osteoporosis. N Engl J Med. 1986; 314:1676-1686. 60531
View PubMed
Wahner HW, Riggs BL. Methods and application of bone densitometry in clinical diagnosis. Crit Rev Clin Lab Sci. 1986; 24(3):217-33. 59412
View PubMed
Riggs BL. Hormonal factors in the pathogenesis of postmenopausal osteoporosis Horm Reprod Metab. 1986; 3:265-73. 155310
Hodgson SF, Dickson ER, Wahner HW, Johnson KA, Mann KG, Riggs BL. Bone loss and reduced osteoblast function in primary biliary cirrhosis. Ann Intern Med. 1985 Dec; 103(6 ( Pt 1)):855-60. 55948
View PubMed
Wahner HW, Eastell R, Riggs BL. Bone mineral density of the radius: where do we stand? J Nucl Med. 1985 Nov; 26(11):1339-41. 1049669
View PubMed
Riggs BL, Nelson KI. Effect of long term treatment with calcitriol on calcium absorption and mineral metabolism in postmenopausal osteoporosis. J Clin Endocrinol Metab. 1985 Sep; 61(3):457-61. 55576
View PubMed
Melton LJ 3rd, Riggs BL. Risk factors for injury after a fall. Clin Geriatr Med. 1985 Aug; 1(3):525-39. 55678
View PubMed
Tiegs RD, Body JJ, Wahner HW, Barta J, Riggs BL, Heath H 3rd. Calcitonin secretion in postmenopausal osteoporosis. N Engl J Med. 1985 Apr 25; 312(17):1097-100. 54716
View PubMed
Firth RG, Grant CS, Riggs BL. Development of hypercalcemic hyperparathyroidism after long-term phosphate supplementation in hypophosphatemic osteomalacia. Report of two cases. Am J Med. 1985 Apr; 78(4):669-73. 54670
View PubMed
Romberg RW, Werness PG, Lollar P, Riggs BL, Mann KG. Isolation and characterization of native adult osteonectin. J Biol Chem. 1985 Mar 10; 260(5):2728-36. 54365
View PubMed
Heath H III, Tiegs RD, Body JJ, Riggs BL Jr, Brennan MD, Wahner HW. Estimates of circulating monomeric calcitonin in man: physiologic and pathophysiologic studies. Int Congr Ser. 1985; 663:57-61. 56325
Hooyman JR, Melton LJ 3rd, Nelson AM, O'Fallon WM, Riggs BL. Fractures after rheumatoid arthritis. A population-based study. Arthritis Rheum. 1984 Dec; 27(12):1353-61. 52984
View PubMed
Richelson LS, Wahner HW, Melton LJ 3rd, Riggs BL. Relative contributions of aging and estrogen deficiency to postmenopausal bone loss. N Engl J Med. 1984 Nov 15; 311(20):1273-5. 52697
View PubMed
Wahner HW, Dunn WL, Riggs BL. Assessment of bone mineral. Part 2. J Nucl Med. 1984 Nov; 25(11):1241-53. 52617
View PubMed
Wahner HW, Dunn WL, Riggs BL Jr. Assessment of bone mineral. Part I. J Nucl Med. 1984 Oct; 25:1134-1141. 52395
View PubMed
Bennett AE, Wahner HW, Riggs BL, Hintz RL. Insulin-like growth factors I and II: aging and bone density in women. J Clin Endocrinol Metab. 1984 Oct; 59(4):701-4. 52363
View PubMed
Tsai KS, Heath H 3rd, Kumar R, Riggs BL. Impaired vitamin D metabolism with aging in women. Possible role in pathogenesis of senile osteoporosis. J Clin Invest. 1984 Jun; 73(6):1668-72. 51734
View PubMed
Delmas PD, Tracy RP, Riggs BL, Mann KG. Identification of the noncollagenous proteins of bovine bone by two-dimensional gel electrophoresis. Calcif Tissue Int. 1984 May; 36(3):308-16. 51776
View PubMed
Stenner DD, Romberg RW, Tracy RP, Katzmann JA, Riggs BL, Mann KG. Monoclonal antibodies to native noncollagenous bone-specific proteins. Proc Natl Acad Sci U S A. 1984 May; 81(9):2868-72. 51599
View PubMed
Christiansen C, Arnaud CD, Nordin BEC, Parfitt AM, Peck WA, Riggs BL Jr. Osteoporosis. Proceedings of the Copenhagen International Symposium on Osteoporosis, June 3-8, 1984. 1984. 1120616
Delmas PD, Stenner DD, Romberg RW, Riggs BL, Mann KG. Immunochemical studies of conformational alterations in bone Gla-containing protein. Biochemistry. 1984; 23:4720-5. 155307
View PubMed
Riggs BL, Melton LJ 3rd. Evidence for two distinct syndromes of involutional osteoporosis. Am J Med. 1983 Dec; 75(6):899-901. 49669
View PubMed
Seeman E, Melton LJ 3rd, O'Fallon WM, Riggs BL. Risk factors for spinal osteoporosis in men. Am J Med. 1983 Dec; 75(6):977-83. 49734
View PubMed
Delmas PD, Wilson DM, Mann KG, Riggs BL. Effect of renal function on plasma levels of bone Gla-protein. J Clin Endocrinol Metab. 1983 Nov; 57(5):1028-30. 49407
View PubMed
Delmas PD, Wahner HW, Mann KG, Riggs BL. Assessment of bone turnover in postmenopausal osteoporosis by measurement of serum bone Gla-protein. Journal of Laboratory & Clinical Medicine. 1983 Oct; 102(4):470-6. 49418
View PubMed
Wahner HW, Dunn WL, Riggs BL. Noninvasive bone mineral measurements. Semin Nucl Med. 1983 Jul; 13(3):282-9. 48952
View PubMed
Delmas PD, Stenner D, Wahner HW, Mann KG, Riggs BL. Increase in serum bone gamma-carboxyglutamic acid protein with aging in women. Implications for the mechanism of age-related bone loss. J Clin Invest. 1983 May; 71(5):1316-21. 48602
View PubMed
Davidson BJ, Riggs BL, Wahner HW, Judd HL. Endogenous cortisol and sex steroids in patients with osteoporotic spinal fractures. Obstetrics & Gynecology. 1983 Mar; 61(3):275-8. 48031
View PubMed
Riggs BL Jr. Questions and answers. Supplemental calcium absorption. JAMA. 1983 Feb 11; 249:815. 1117919
View PubMed
Riggs BL Jr, Melton LJ, Wahner HW. Heterogeneity of involutional osteoporosis: evidence for two distinct osteoporosis syndromes. Int Congr Ser. 1983; 617:337-342. 49790
Wahner HW, Dunn WL, Offord K, Riggs BL Jr. Dual-photon absorptiometry: clinical considerations. Int Congr Ser. 1983; 617:34-39. 49791
Owen RA, Melton LJ 3rd, Ilstrup DM, Johnson KA, Riggs BL. Colles' fracture and subsequent hip fracture risk. Clin Orthop. 1982 Nov-Dec; (171):37-43. 46924
Riggs BL, Wahner HW, Seeman E, Offord KP, Dunn WL, Mazess RB, Johnson KA, Melton LJ 3rd. Changes in bone mineral density of the proximal femur and spine with aging. Differences between the postmenopausal and senile osteoporosis syndromes. J Clin Invest. 1982 Oct; 70(4):716-23. 46378
View PubMed
Rose SH, Melton LJ 3rd, Morrey BF, Ilstrup DM, Riggs BL. Epidemiologic features of humeral fractures. Clin Orthop. 1982 Aug; 168:24-30. 46000
View PubMed
Melton LJ 3rd, Ilstrup DM, Beckenbaugh RD, Riggs BL. Hip fracture recurrence. A population-based study. Clin Orthop. 1982 Jul; 167:131-8. 45836
View PubMed
Seeman E, Wahner HW, Offord KP, Kumar R, Johnson WJ, Riggs BL. Differential effects of endocrine dysfunction on the axial and the appendicular skeleton. J Clin Invest. 1982 Jun; 69(6):1302-9. 1312680
View PubMed
Owen RA, Melton LJ 3rd, Johnson KA, Ilstrup DM, Riggs BL. Incidence of Colles' fracture in a North American community. Am J Public Health. 1982 Jun; 72(6):605-7. 45669
View PubMed
Gallagher JC, Jerpbak CM, Jee WS, Johnson KA, DeLuca HF, Riggs BL. 1,25-Dihydroxyvitamin D3: short- and long-term effects on bone and calcium metabolism in patients with postmenopausal osteoporosis. Proc Natl Acad Sci U S A. 1982 May; 79(10):3325-9. 45564
View PubMed
Riggs BL, Seeman E, Hodgson SF, Taves DR, O'Fallon WM. Effect of the fluoride/calcium regimen on vertebral fracture occurrence in postmenopausal osteoporosis. Comparison with conventional therapy. N Engl J Med. 1982 Feb 25; 306(8):446-50. 45044
View PubMed
Wahner HW, Dunn WL, Riggs BL Jr. Age related bone loss in predominantly cortical and trabecular bone sites measured by photon absorptiometry. J Comput Assist Tomogr. 1982 Feb; 6:209-210. 45016
Melton LJ 3rd, Ilstrup DM, Riggs BL, Beckenbaugh RD. Fifty-year trend in hip fracture incidence. Clin Orthop. 1982 Jan-Feb; (162):144-9. 45203
Riggs BL, Hamstra A, DeLuca HF. Assessment of 25-hydroxyvitamin D 1 alpha-hydroxylase reserve in postmenopausal osteoporosis by administration of parathyroid extract. J Clin Endocrinol Metab. 1981 Oct; 53(4):833-5. 43369
View PubMed
Seeman E, Riggs BL. Dietary prevention of bone loss in the elderly. Geriatrics. 1981 Sep; 36(9):71-3, 75, 79. 43243
View PubMed
Kumar R, Riggs BL Jr. Series on pharmacology in practice: 11. Vitamin D in the therapy of disorders of calcium and phosphorus metabolism. Mayo Clin Proc. 1981 May; 56:327-333. 42646
View PubMed
Riggs BL, Wahner HW, Dunn WL, Mazess RB, Offord KP, Melton LJ 3rd. Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest. 1981 Feb; 67(2):328-35. 42364
View PubMed
Riggs BL. Etiology and treatment of postmenopausal osteoporosis. Rheumatologie. 1981; 33:255-62. 155296
Gallagher JC, Riggs BL, DeLuca HF. Effect of estrogen on calcium absorption and serum vitamin D metabolites in postmenopausal osteoporosis. J Clin Endocrinol Metab. 1980 Dec; 51(6):1359-64. 41030
View PubMed
Gallagher JC, Melton LJ, Riggs BL. Examination of prevalence rates of possible risk factors in a population with a fracture of the proximal femur. Clin Orthop. 1980 Nov-Dec; (153):158-65. 41138
Seeman E, Kumar R, Hunder GG, Scott M, Heath H 3rd, Riggs BL. Production, degradation, and circulating levels of 1,25-dihydroxyvitamin D in health and in chronic glucocorticoid excess. J Clin Invest. 1980 Oct; 66(4):664-9. 40669
View PubMed
Dunn WL, Wahner HW, Riggs BL. Measurement of bone mineral content in human vertebrae and hip by dual photon absorptiometry. Radiology. 1980 Aug; 136(2):485-7. 40457
View PubMed
Owen RA, Melton LJ 3rd, Gallagher JC, Riggs BL. The national cost of acute care of hip fractures associated with osteoporosis. Clin Orthop. 1980 Jul-Aug; (150):172-6. 40399
Gallagher JC, Melton LJ, Riggs BL, Bergstrath E. Epidemiology of fractures of the proximal femur in Rochester, Minnesota. Clin Orthop. 1980 Jul-Aug; (150):163-71. 1318065
Gallagher JC, Riggs BL, Jerpbak CM, Arnaud CD. The effect of age on serum immunoreactive parathyroid hormone in normal and osteoporotic women. Journal of Laboratory & Clinical Medicine. 1980 Mar; 95(3):373-85. 39913
View PubMed
Davidson BJ, Riggs BL, Coulam CB, Toft DO. Concentration of cytosolic estrogen receptors in patients with postmenopausal osteoporosis. American Journal of Obstetrics & Gynecology. 1980 Feb 15; 136(4):430-3. 41496
View PubMed
Kumar R, Abboud CF, Riggs BL. The effect of elevated prolactin levels on plasma 1,25-dihydroxyvitamin D and intestinal absorption of calcium. Mayo Clin Proc. 1980 Jan; 55(1):51-3. 39690
View PubMed
Wahner HW, Dunn W, Riggs BL Jr. Bone mineral measurements by dual photon absorptiometry. Nuklearmedizin Suppl. 1980; 17:98-102. 40649
Riggs BL Jr, Hodgson SF, Hoffman DL, Kelly PJ, Johnson KA. Treatment of primary osteoporosis with fluoride and calcium: clinical tolerance and fracture occurrence. JAMA. 1980; 243:446-449. 39986
View PubMed
Riggs BL. Calcitriol in disorders of bone and calcium metabolism Clin Therapeutics. 1980; 3:33-39. 155295
Gallagher JC, Riggs BL, Eisman J, Hamstra A, Arnaud SB, DeLuca HF. Intestinal calcium absorption and serum vitamin D metabolites in normal subjects and osteoporotic patients: effect of age and dietary calcium. J Clin Invest. 1979 Sep; 64(3):729-36. 38052
View PubMed
Riggs BL. Postmenopausal and senile osteoporosis: current concepts of etiology and treatment. Endocrinol Jpn. 1979 Jun; 26(Suppl):31-41. 38849
View PubMed
Riggs BL, Gallagher JC, DeLuca HF, Edis AJ, Lambert PW, Arnaud CD. A syndrome of osteoporosis, increased serum immunoreactive parathyroid hormone, and inappropriately low serum 1,25-dihydroxyvitamin D. Mayo Clin Proc. 1978 Nov; 53(11):701-6. 36044
View PubMed
Jowsey J, Riggs BL, Kelly PJ, Hoffman DL. Calcium and salmon calcitonin in treatment of osteoporosis. J Clin Endocrinol Metab. 1978 Sep; 47(3):633-9. 35811
View PubMed
Jowsey J, Riggs BL. Effect of concurrent calcium ingestion on intestinal absorption of fluoride. Metabolism: Clinical & Experimental. 1978 Aug; 27(8):971-4. 36453
View PubMed
Nelson AM, Riggs BL, Jowsey JO. Atypical axial osteomalacia. Report of four cases with two having features of ankylosing spondylitis. Arthritis Rheum. 1978 Jul-Aug; 21(6):715-22. 35735
View PubMed
Gallagher JC, Riggs BL. Current concepts in nutrition. Nutrition and bone disease. N Engl J Med. 1978 Jan 26; 298(4):193-5. 35364
View PubMed
Riggs BL Jr, Gallagher JC. Intestinal calcium absorption in postmenopausal osteoporosis: possible role of vitamin D. Int Congr Ser. 1978; 421:43-47. 36366
Klein RG, Arnaud SB, Gallagher JC, Deluca HF, Riggs BL. Intestinal calcium absorption in exogenous hypercortisonism. Role of 25-hydroxyvitamin D and corticosteroid dose. J Clin Invest. 1977 Jul; 60(1):253-9. 33831
View PubMed
Wahner HW, Riggs BL, Beabout JW. Diagnosis of osteoporosis: usefulness of photon absorptiometry at the radius. J Nucl Med. 1977 May; 18(5):432-7. 33700
View PubMed
Goldsmith RS, Jowsey J, Dube WJ, Riggs BL, Arnaud CD, Kelly PJ. Effects of phosphorus supplementation on serum parathyroid hormone and bone morphology in osteoporosis. J Clin Endocrinol Metab. 1976 Sep; 43(3):523-32. 32834
View PubMed
Bartizal FJ, Coulam CB, Gaffey TA, Ryan RJ, Riggs BL. Impaired binding of estradiol to vaginal mucosal cells in post-menopausal osteoporosis. Calcif Tissue Res. 1976 Aug; 21(Suppl):412-6. 32835
View PubMed
Riggs BL Jr, Jowsey J, Kelly PJ, Arnaud CD. Role of hormonal factors in pathogenesis of postmenopausal osteoporosis. Isr J Med Sci. 1976 Jul; 12:615-619. 32343
View PubMed
Riggs BL, Jowsey J, Kelly PJ, Hoffman DL, Arnaud CD. Effects of oral therapy with calcium and vitamin D in primary osteoporosis. J Clin Endocrinol Metab. 1976 Jun; 42(6):1139-44. 31839
View PubMed
Bartizal FJ, Coulam CB, Gaffey TA, Ryan RJ, Riggs BL Jr. Impaired binding of estradiol to vaginal mucosal cells in postmenopausal osteoporosis. Gynecol Invest. 1976; 7:330-336. 32833
Dauphine RT, Riggs BL, Scholz DA. Back pain and vertebral crush fractures: an unemphasized mode of presentation for primary hyperparathyroidism. Ann Intern Med. 1975 Sep; 83(3):365-7. 30353
View PubMed
Smith LH, Riggs BL. Clinical and laboratory considerations in metabolic bone disease. Ann Clin Lab Sci. 1975 Jul-Aug; 5(4):252-6. 30300
View PubMed
Maldonado JE, Riggs BL, Bayrd ED. Pseudomyeloma. Is association of severe osteoporosis with serum monoclonal gammopathy an entity or a coincidence? Arch Intern Med. 1975 Feb; 135(2):267-70. 29902
View PubMed
Scholz DA, Purnell DC, Goldsmith RS, Smith LH, Riggs B, Arnaud CD. Hypercalcemia and cancer. CA Cancer J Clin. 1975 Jan-Feb; 25(1):27-30. 1101124
View PubMed
Benson RC Jr, Riggs BL, Pickard BM, Arnaud CD. Immunoreactive forms of circulating parathyroid hormone in primary and ectopic hyperparathyroidism. J Clin Invest. 1974 Jul; 54(1):175-81. 28524
View PubMed
Benson RC Jr, Riggs BL, Pickard BM, Arnaud CD. Radioimmunoassay of parathyroid hormone in hypercalcemic patients with malignant disease. Am J Med. 1974 Jun; 56(6):821-6. 29123
View PubMed
Jowsey J, Riggs BL Jr, Kelly PJ. Treatment of postmenopausal or senile osteoporosis. Rheumatology (Oxford) 1974 May; 4:567-72. 29280
Riggs BL. Management of postmenopausal and senile osteoporosis. J Ark Med Soc. 1974 Mar; 70(10):317-22. 29500
View PubMed
Riggs BL Jr. Questions and answers. Bone disease associated with malabsorption: osteoporosis or osteomalacia? J Am Med Assoc. 1974; 230(10):1442-1443. 1099876
Langloh ND, Hunder GG, Riggs BL, Kelly JP. Transient painful osteoporosis of the lower extremities. Journal of Bone and Joint Surgery. American Volume. 1973 Sep; 55(6):1188-96. 27076
View PubMed
Riggs B, Jowsey J, Kelly PJ, Arnaud CD. Bone turnover-sex hormone-parathyroid hormone interrelationships in postmenopausal osteoporosis. Boll Soc Ital Biol Sper. 1973 Jul 30; 49(12):732-7. 27759
View PubMed
Riggs BL, Jowsey J, Kelly PJ, Hoffman DL, Arnaud CD. Studies on pathogenesis and treatment in postmenopausal and senile osteoporosis. Clinics in Endocrinology & Metabolism. 1973 Jul; 2(2):317-32. 1312243
View PubMed
Riggs BL, Ryan RJ, Wahner HW, Jiang NS, Mattox VR. Serum concentrations of estrogen, testosterone, and gonadotropins in osteoporotic and nonosteoporotic postmenopausal women. J Clin Endocrinol Metab. 1973 Jun; 36(6):1097-9. 26745
View PubMed
Riggs BL Jr, Jowsey J. Management of postmenopausal and senile osteoporosis. Drug Ther. 1973 May; 3:45-53. 26675
Jowsey J, Riggs BL Jr. Seeking successful treatment for osteoporosis. Mod Med. 1973 Mar 5; 41:36-42. 1098256
Singh M, Riggs BL, Beabout JW, Jowsey J. Femoral trabecular pattern index for evaluation of spinal osteoporosis. A detailed methodologic description. Mayo Clin Proc. 1973 Mar; 48(3):184-9. 1312250
View PubMed
Scholz DA, Riggs BL Jr, Purnell DC, Goldsmith RS, Arnaud CD. Ectopic hyperparathyroidism with renal calculi and subperiosteal bone resorption. Mayo Clin Proc. 1973 Feb; 48:124-126. 26427
View PubMed
Riggs BL, Arnaud CD, Jowsey J, Goldsmith RS, Kelly PJ. Parathyroid function in primary osteoporosis. J Clin Invest. 1973 Jan; 52(1):181-4. 26375
View PubMed
Riggs BL Jr, Jowsey J, Kelly PJ. Three-stage medical therapy improves osteoporosis results. Internist Obs. 1973; 11:2. 27893
Jowsey J, Riggs BL Jr, Kelly PJ. The etiology and treatment of osteoporosis. Int Congr Ser. 1973; 291:358-363. 27596
Riggs BL Jr, Jowsey J, Kelly PJ, Hoffman DL. Quantitative evaluation of therapy for postmenopausal and senile osteoporosis. Int Congr Ser. 1973; 270:318-328. 27462
Jowsey J, Riggs BL, Kelly PJ. New concepts in the treatment of osteoporosis. Postgrad Med. 1972 Oct; 52(4):62-7. 25418
View PubMed
Scholz DA, Purnell DC, Goldsmith RS, Smith LH, Riggs BL, Arnaud CD. Diagnostic considerations in hypercalcemic syndromes. Med Clin North Am. 1972 Jul; 56(4):941-50. 25101
View PubMed
Riggs BL, Jowsey J, Kelly PJ, Hoffman DL. Treatment for postmenopausal and senile osteoporosis. Med Clin North Am. 1972 Jul; 56(4):989-97. 25116
View PubMed
Riggs BL Jr, Jowsey J, Goldsmith RS, Kelly PJ, Hoffman DL, Arnaud CD. Short-term and long-term effects of estrogen and synthetic anabolic hormone in postmenopausal osteoporosis. J Clin Invest. 1972 Jul; 51:1659-1663. 25122
View PubMed
Singh M, Riggs BL, Beabout JW, Jowsey J. Femoral trabecular-pattern index for evaluation of spinal osteoporosis. Ann Intern Med. 1972 Jul; 77(1):63-7. 1312232
View PubMed
Jowsey J, Riggs BL, Kelly PJ, Hoffmann DL. Effect of combined therapy with sodium fluoride, vitamin D and calcium in osteoporosis. Am J Med. 1972 Jul; 53(1):43-9. 1312233
View PubMed
Riggs BL, Jowsey J. Treatment of Paget's disease with fluoride. Semin Drug Treat. 1972 Summer; 2(1):65-8. 25197
View PubMed
Riggs BL, Jowsey J. Treatment of osteoporosis with fluoride. Semin Drug Treat. 1972 Summer; 2(1):27-33. 25199
View PubMed
Riggs BL, Randall RV, Wahner HW, Jowsey J, Kelly PJ, Singh M. The nature of the metabolic bone disorder in acromegaly. J Clin Endocrinol Metab. 1972 Jun; 34(6):911-8. 25075
View PubMed
Jowsey J, Riggs BL. Assessment of bone turnover by microradiography and autoradiography. Semin Nucl Med. 1972 Jan; 2(1):3-17. 24691
View PubMed
Riggs BL Jr, Arnaud CD, Smith LH. Immunologic differentiation of primary hyperparathyroidism from hyperparathyroidism due to non-parathyroid cancer. Int Congr Ser. 1972; 243:210-212. 24943
Jowsey J, Riggs BL, Goldsmith RS, Kelly PJ, Arnaud CD. Effects of prolonged administration of porcine calcitonin in postmenopausal osteoporosis. J Clin Endocrinol Metab. 1971 Nov; 33(5):752-8. 24060
View PubMed
Johnson KA, Riggs BL, Kelly PJ, Jowsey J. Osteoid tissue in normal and osteoporotic individuals. J Clin Endocrinol Metab. 1971 Nov; 33(5):745-51. 24062
View PubMed
Jowsey J, Riggs BL Jr, Kelly PJ, Hoffman DL, Bordier P. The treatment of osteoporosis with disodium ethane-1-hydroxy-1,1-diphosphonate. J Lab Clin Med. 1971 Oct; 78:574-584. 24105
View PubMed
Riggs BL, Arnaud CD, Reynolds JC, Smith LH. Immunologic differentiation of primary hyperparathyroidism from hyperparathyroidism due to nonparathyroid cancer. J Clin Invest. 1971 Oct; 50(10):2079-83. 23785
View PubMed
Riggs BL Jr, Marshall JH, Jowsey J, Heaney RP, Bassingthwaighte JB. Quantitative Ca45 antoradiography of human bone. J Lab Clin Med. 1971 Oct; 78:585-598. 24598
View PubMed
Riggs BL, Arnaud CD, Goldsmith RS, Taylor WF, McCall JT, Sessler AD. Plasma kinetics and acute effects of pharmacologic doses of porcine calcitonin in man. J Clin Endocrinol Metab. 1971 Jul; 33(1):115-27. 23635
View PubMed
Riggs BL, Jowsey J, Kelly PJ, Wahner HW. Special procedures for assessing metabolic bone disease. Med Clin North Am. 1970 Jul; 54(4):1061-70. 22127
View PubMed
Stickler GB, Beabout JW, Riggs BL. Vitamin D-resistant rickets: clinical experience with 41 typical familial hypophosphatemic patients and 2 atypical nonfamilial cases. Mayo Clin Proc. 1970 Mar;45(3):197-218. 1092489
View PubMed
Riggs BL Jr, Bassingthwaighte JB, Jowsey J, Pequegnat EP. Autoradiographic method for quantitation of deposition and distribution of radiocalcium in bone. J Lab Clin Med. 1970 Mar; 75:520-528. 21809
View PubMed
Jowsey J, Riggs BL. Bone formation in hypercortisonism. Acta Endocrinol (Copenh) 1970 Jan; 63(1):21-8. 21765
View PubMed
Riggs BL, Sprague RG, Jowsey J, Maher FT. Adult-onset vitamin-D-resistant hypophosphatemic osteomalacia. Effect of total parathyroidectomy. N Engl J Med. 1969 Oct 2; 281(14):762-6. 20887
View PubMed
Plummer AL, Randall RV, Riggs BL. Active acromegaly with anterior pituitary failure. Metabolism: Clinical & Experimental. 1969 Jun; 18(6):469-75. 20837
View PubMed
Riggs BL, Jowsey J, Kelly PJ, Jones JD, Maher FT. Effect of sex hormones on bone in primary osteoporosis. J Clin Invest. 1969 Jun; 48(6):1065-72. 20615
View PubMed
Jowsey J, Riggs BL. Bone changes in a patient with hypervitaminosis A. J Clin Endocrinol Metab. 1968 Dec; 28(12):1833-5. 19834
View PubMed
Riggs BL Jr. Diagnosis and treatment of primary osteoporosis. Postgrad Med. 1968 Oct; 44:224-229. 19593
Riggs BL Jr, Jones JD, Arnaud CD. Effect of calcium infusion on serum calcium levels in hypothyroidism. Metabolism. 1968 Aug; 17:747-750. 19456
View PubMed
Adams P, Chalmers TM, Riggs BL Jr, Jones JD. Parathyroid function in spontaneous primary hypothyroidism. J Endocrinol. 1968 Apr; 40(4):467-75. 19331
View PubMed
Riggs BL, Jowsey J, Ackerman E, Hazelrig JB. Ability of 47 Ca kinetic analysis to discriminate metabolic states affecting bone formation in dogs. Metabolism: Clinical & Experimental. 1967 Nov; 16(11):1064-73. 18427
View PubMed
Cloutier MD, Hayles AB, Riggs BL Jr, Jowsey J, Bickel WH. Juvenile osteoporosis. Report of a case including a description of some metabolic and microradiographic studies. Pediatrics. 1967 Oct; 40:649-655. 18494
View PubMed
Birtwell WM Jr, Riggs L, Peterson LF, Jones JD. Hypophosphatasia in an adult. Arch Intern Med. 1967 Jul; 120(1):90-3. 18189
View PubMed
Riggs BL, Kelly PJ, Kinney WR, Scholz DA, Bianco AJ Jr. Calcium deficiency and osteoporosis. Observations in one hundred and sixty-six patients and critical review of the literature. Journal of Bone and Joint Surgery. American Volume. 1967 Jul; 49(5):915-24. 18193
View PubMed
Adams PH, Jowsey J, Kelly PJ, Riggs BL Jr, Kinney VR, Jones JD. Effects of hyperthyroidism on bone and mineral metabolism in man. Q J Med. 1967 Jan; 36:1-15. 18098
Kelly PJ, Jowsey J, Riggs BL, Elveback LR. Relationship between serum phosphate concentration and bone resorption in osteoporosis. Journal of Laboratory & Clinical Medicine. 1967 Jan; 69(1):110-5. 17922
View PubMed
Riggs BL, Jowsey J, Kelly PJ. Quantitative microradiographic study of bone remodeling in Cushing's syndrome. Metabolism: Clinical & Experimental. 1966 Sep; 15(9):773-80. 17139
View PubMed
Jowsey J, Kelly PJ, Riggs BL Jr, Bianco AJ Jr, Scholz DA, Gershon-Cohen J. Quantitative microradiographic studies of normal and osteoporotic bone. J Bone Joint Surg. 1965 Jun; 47-A,785-806:872. 15749
Riggs BL Jr, Kelly PJ, Jowsey J, Keating FR Jr. Skeletal alterations in hyperparathyroidism, determination of bone formation, resorption, and morphologic changes by microradiography. J Clin Endocrinol. 1965 Jun; 25:777-783. 15764
Kelly PJ, Jowsey J, Riggs BL Jr. A comparison of different morphologic methods of determining bone formation. Clin Orthop. 1965 May-Jun; 40:7-11. 15901
View PubMed
Jowsey J, Riggs BL Jr, Kelly PJ. Mineral metabolism in osteocytes. Mayo Clin Proc. 1964 Jul; 39:480-484. 14633
View PubMed
Scholz DA, Riggs BL Jr, Bahn RC, Liddle GW. Clinics on endocrine and metabolic disease. 8. Adrenocortical hyperfunction associated with a corticotropin-secreting bronchogenic carcinoma, report of case. Proc Staff Meet Mayo Clin. 1963 Jan 30; 38:45-51. 13439
Riggs BL Jr, Jones JD, Randall RV. Clinics on endocrine and metabolic diseases. 7. Primary hyperparathyroidism, report of a case in which the diagnosis was made by serendipity. Proc Staff Meet Mayo Clin. 1962 Apr 25; 37:250-252. 12604
Riggs BL Jr, Sprague RG. Association of Cushing's syndrome and neoplastic disease, observations in 232 cases of Cushing's syndrome and review of literature. Arch Intern Med. 1961 Dec; 108:841-849. 11659
View PubMed
Riggs BL Jr, Geraci JE, Prickman LE. Untoward reactions to antibiotics. Minn Med. 1961 Oct; 44:406-416. 11658
View PubMed
Riggs BL Jr, Randall RV. Clinics on endocrine and metabolic diseases. 2. Diabetes insipidus and diabetes mellitus, report of case. Proc Staff Meet Mayo Clin. 1960 Jan 20; 35:30-33. 10752

Publications

Mayo Clinic Footer

Legal Conditions and Terms

Advertising

Reprints