Crystal A. Mendoza

  • Adviser: Roberto Cattaneo, Ph.D.
  • Area of emphasis: Molecular virology
  • Research area: Measles virus epithelial spread

What are your research interests?

Dr. Cattaneo's lab works on the measles virus, which has continued to be a major public health issue in recent years.

My work focuses on the spread of measles virus in airway epithelia. Using an airway epithelial model, we can track spread of viral components over time and learn how measles hijacks the epithelia to spread quickly, efficiently and discreetly. Additionally, we ask fundamental questions about how the function of the viral proteins impact spread.

Overall, our research is important because it addresses questions of how measles virus spreads within the host and between hosts, leading to it being the most contagious virus known.

Why did you choose Mayo Clinic Graduate School of Biomedical Sciences' Virology and Gene Therapy track?

The amazing research being done at Mayo Clinic is what initially led me to apply, and the molecular virology research being done was not only interesting, but cutting edge. Mayo felt like home during interview weekend. The track provides not only a strong foundation of molecular virology, but teaches possible applications for therapies and treatments.

Leadership

  • Manager, Diversity in Education Blog, Mayo Clinic Graduate School of Biomedical Sciences, 2014-present
  • Virology and Gene Therapy track representative, Mayo Graduate Students Association, 2015-2016

Posters

  • Mendoza C, Mateo M, Cattaneo R. The role of the measles virus matrix protein in cell-associated epithelial spread. Poster presented at: Annual Society for the Advancement of Chicanos and Native Americans (SACNAS) National Conference; 2015; Washington, D.C.
  • Rapid measles virus intercellular transport in the airway epithelium: roles of the matrix protein. Poster presented at: Mayo Graduate School Research Symposium; 2014; Rochester, Minn.
  • Roles of the matrix protein in measles virus intercellular spread. Poster presented at: Mayo Graduate School Research Symposium; 2015; Rochester, Minn.

Presentations

  • The role of the measles virus matrix protein in cell-associated epithelial spread. Presentation at: American Society for Virology Annual Meeting; 2015; London, Ontario, Canada.
  • The nectin-4-afadin complex and intercellular membrane pores contribute to rapid spread of measles virus in primary human airway epithelia. Presentation at: Institute for Molecular Virology Symposium; 2015; Minneapolis, Minn.

Affiliations

  • Initiatives for Maximizing Student Development
  • American Society for Virology
  • Society for Advancement of Chicanos/Hispanics and Native Americans in Science (SACNAS)

Publications

Nov. 17, 2015