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Clinical and Laboratory Training

During this fellowship you will participate in all the activities of the BMT group. An outline of a typical rotation schedule follows; it can be tailored slightly to fit specific career interests.


Rotation Length
Outpatient BMT 4 months
Inpatient BMT 4 months
Transfusion Medicine
  • Tissue Typing
  • Progentor Cell Laboratory
  • Apheresis Laboratory
2 months
Research Elective 2 months

Rotation Descriptions

Inpatient BMT

During the time spent in the clinical BMT Service, you will acquire experience in blood and marrow harvesting, peripheral stem cell and blood and marrow infusions, management of acute and chronic GVHD and supportive care of the transplanted patient.

Outpatient BMT

Fellows will also acquire experience in the outpatient evaluation and management of BMT patients. Because of the close proximity of the outpatient clinic to the BMT unit, fellows are able to follow patients longitudinally.

Apheresis Laboratory

Fellows receive training in approaches to peripheral blood stem cell collection and become familiar with a wide range of plasma and cytapheresis procedures. These procedures are performed as part of various therapeutic regimens and to acquire single donor platelets or granulocytes for transfusion purposes.

Tissue Typing

During this rotation you will gain experience with:

  • Class I and Class II HLA typing and lymphocyte separation techniques, their applications and limitations
  • Granulocyte and platelet antibody testing
  • Lymphocyte cross matching
  • HLA antibody testing

Progenitor Cell Laboratory

Fellows are exposed to a state-of-the-art progenitor cell laboratory where they learn about cell cryopreservation. They are also exposed to various clinical trials including dendritic cell therapy and haploidentical transplant trials. Their involvement can be substantial, depending on your level of interest.

Research Elective

Fellows will spend 2 months conducting clinical or laboratory research in cooperation with clinical and laboratory investigators in hematology. Basic science projects are also available in cooperation with Biochemistry, Experimental Pathology, Immunology, Molecular Biology, Molecular Genetics and Pharmacology.

Didactic Training

Clinical conferences, seminars, small discussion groups, journal clubs and on-on-one instruction are all an integral part of the BMT Fellowship. For example, a variety of conferences are available, including Transplant Grand Rounds, transplantation core curriculum, journal clubs, hematology core and clinical conferences and hematology visiting faculty dinners. Fellows are expected to present one transplantation Grand Rounds talk on their research or an interesting blood and marrow transplant topic.

Research Training

Your research opportunities at Mayo Clinic are outstanding. You are encouraged to participate in research projects with the consulting staff which include opportunities for clinical studies and laboratory-based projects.


To ensure you gain proficiency and develop the corresponding technical skills, your performance is monitored throughout this program. You are formally evaluated by your supervising faculty member following the completion of each clinical rotation; and then meet accordingly with the program director to review these evaluations. In addition, you regularly evaluate the faculty to ensure your educational goals are being met.

Call Frequency

The residency call rotation is different for each rotation. Mayo Clinic College of Medicine follows the recommendations of the Accreditation Council for Graduate Medical Education (ACGME).

Teaching Opportunities

You will have the opportunity to teach Mayo Medical School students and visiting students from other national and international medical schools through bedside instruction and formal didactic lectures.

  • May 10, 2012
  • ART402045