During the Blood and Marrow Transplant Fellowship, you participate in all the activities of the blood and marrow transplant (BMT) group.
The following is an outline of a typical rotation schedule. It can be tailored slightly to fit specific career interests.
- Tissue typing
- Progenitor cell laboratory
- Apheresis laboratory
Fellows acquire experience in the outpatient evaluation and management of BMT patients. Because of the close proximity of the outpatient clinic to the BMT unit, fellows are able to follow patients longitudinally.
During the time spent in the clinical BMT service, you acquire experience in blood and marrow harvesting, peripheral stem cell and blood and marrow infusions, management of acute and chronic graft-versus-host disease, and supportive care of transplanted patients.
- Tissue typing. During this rotation, you gain experience with:
- Class I and class II HLA typing and lymphocyte separation techniques, as well as their applications and limitations
- Granulocyte and platelet antibody testing
- Lymphocyte cross matching
- HLA antibody testing
- Progenitor cell laboratory. Fellows are exposed to a state-of-the-art progenitor cell laboratory where they learn about cell cryopreservation. They are also exposed to various clinical trials, including dendritic cell therapy and haploidentical transplant trials. Your involvement can be substantial, depending on your level of interest.
- Apheresis laboratory. Fellows receive training in approaches to peripheral blood stem cell collection and become familiar with a wide range of plasma and cytapheresis procedures. These procedures are performed as part of various therapeutic regimens and to acquire single donor platelets or granulocytes for transfusion purposes.
Fellows spend two months conducting clinical or laboratory research in cooperation with clinical and laboratory investigators in hematology. Basic science projects are also available in cooperation with Mayo colleagues in biochemistry, experimental pathology, immunology, molecular biology, molecular genetics and pharmacology.
Clinical conferences, seminars, small discussion groups, journal clubs and one-on-one instruction are all integral parts of the Blood and Marrow Transplant Fellowship.
For example, a variety of conferences are available, including Transplant Grand Rounds, transplantation core curriculum, journal clubs, hematology core and clinical conferences, and hematology visiting faculty dinners. Fellows are expected to present one Transplant Grand Rounds talk on their research or an interesting blood and marrow transplant topic.
Your research opportunities at Mayo Clinic are outstanding. You are encouraged to participate in research projects with the consulting staff, which include opportunities for clinical studies and laboratory-based projects.
The residency call rotation is different for each rotation. Mayo Clinic College of Medicine follows the recommendations of the Accreditation Council for Graduate Medical Education.
You have the opportunity to teach Mayo Medical School students and visiting students from other national and international medical schools through bedside instruction and formal didactic lectures.
To ensure you gain proficiency and develop the corresponding technical skills, your performance is monitored throughout the Blood and Marrow Transplant Fellowship. You are formally evaluated by your supervising faculty member following the completion of each clinical rotation, and you then meet with the program director to review these evaluations. In addition, you regularly evaluate the faculty to ensure your educational goals are being met.