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Research Facilities and Groups
The following research facilities and resources at Mayo Clinic in Rochester augment the General Internal Medicine Research Fellowship:
- Center for Translational Science Activities (CTSA) Service Center
The Center for Translational Science Activities (CTSA) Service Center is a support center designed to help those at Mayo Clinic involved in clinical research conducted with human subjects. The CTSA Service Center provides consultative and support services vital to the efficient conduct of clinical research. The mission of the Center for Translational Science Activities (CTSA) Service Center is to: 1) Provide consultative services to enhance Mayo Clinic patient-oriented research; 2) Educate clinical research investigators to design, conduct, and analyze their own research; 3) Provide educational opportunities to promote quality staff development, professional growth, and job enrichment for all individuals in clinical research study coordination at Mayo; 4) Increase minority research recruitment into clinical studies and deepen community relationships with minority populations through outreach; and 5) As a team, provide the highest level of service to every customer, every day.
- Division of Epidemiology
In the Division of Epidemiology, research priorities are directed toward questions arising from programmatic areas of research excellence within the institution, as well as important clinical practice questions about the application of specific diagnostic and/or therapeutic technologies.
Collaborative opportunities exist with this group in the areas of cancer and genetic epidemiology. Mayo Clinic has directly received, and is collaborating with institutions who have received, National Institutes of Health (NIH) - funded SPOREs (Specialized Program of Research Excellence) in brain, breast, pancreatic, and prostate cancer as well as lymphoma and myeloma.
- Core Facilities
Mayo Clinic's state-of-the-art research facilities are designed to support Mayo investigators for the express purpose of maintaining the quality and competitiveness of research. The services within the Research Committee-sponsored core facilities are available to all Mayo Clinic investigators engaged in clinical or basic research with approved peer-reviewed protocols or established research programs.
Our research core facilities include:
- Bio-Informatics
- Biospecimens Accessioning and Processing (BAP)
- Biomedical Imaging
- Biomedical Informatics
- Biostatistics
Data Analysts
Data Processing
MS Statisticians
- Cancer Informatics
- Comparative Medicine
- Cytogenetics
- Diagnostic Radiology
- Electron Microscopy
- Flow Cytometry
- Gene and Virus Therapy
- Genotyping
- Immunotherapy
- Materials and Structure Testing
- Microarray
- Molecular Biology
- Mouse Antibody
- Nuclear Magnetic Resonance
- Preparation and Processing
- Proteomics
- RCF - Collaborative Consulting
- Research Drug Dispensary
- Survey Research Center
- Tissue and Cell Molecular Analysis
- Transgenic and Gene Knock-out
- Wettstein T-Cell
Additional research facilities include:
- Histology Facility
- Large Animal Facility
- Research Graphics
- Mayo Rochester Epidemiology Project (REP)
Population-based epidemiologic research can be conducted in Olmsted County, Minnesota, because medical records for the entire population are available from most providers of care. The REP provides investigators with access to the details of the medical care provided to residents of Rochester and Olmsted County at both Mayo Clinic and the other area medical care facilities.
The significance of the Rochester Epidemiology Project lies in its ability to provide accurate descriptive information for nearly any disease or syndrome and the ability to conduct population-based analytic studies of disease etiology and outcome. This may be the only source of such data for conditions treated predominantly on an outpatient basis.
Interdisciplinary Research Programs in General Medicine
Mayo Clinic has specially focused research centers in several areas, including:
- Nicotine Dependence Center (NRP)
The Mayo Clinic NRP is the research arm of the Mayo Clinic Nicotine Dependence Center. The Mayo NRP has been active since 1988 and its staff has performed a wide range of studies. The NRP has enrolled more than 10,000 subjects in over 75 clinical trials.
- Alzheimer's Disease Research Center (ADRC)
The ADRC has significantly contributed to the literature on mild cognitive impairment and normal cognition. Research opportunities exist in the large, community-based cohort of patients. Therapeutic and diagnostic trials are ongoing.
- Vaccine Research Group (VRG)
The Vaccine Research Group (VRG) is organized under the Clinical Pharmacology unit within the Department of Medicine. Formally organized in 1989, the VRG was founded and is headed by Gregory A. Poland, M.D. This group conducts NIH-funded research investigating the immunogenetics of vaccine response and also conducts clinical studies of novel vaccines and adjuvants in adults and children. The VRG successfully combines laboratory facilities for immunologic testing including serology, cell-mediated immunity, cell culture, and cytokine assays along with PCR techniques and HLA typing for immunogenetic studies using the resources of the Rochester Epidemiology Project. Robert M. Jacobson, M.D., heads the clinical trials component of the VRG, which conducts trials including the Anthrax Vaccine Study and the Smallpox Vaccine Study.
- Biomedical Informatics (BMI)
BMI engages clinicians, scientists, and allied health colleagues in a systematic program of research and development in the domains of computer science, language processing, concept representation, information retrieval, and computational biology. BMI enables focused enhancements for Mayo practice, research, and education through research, development, and evaluation of: 1) Infrastructures and methods for the management and retrieval of patient and genomic data; 2) Classification and terminology systems in knowledge contexts; 3) Bioinformatics methods, deployment, and investigator support; and 4) Health and genomics standards development and open source collaboration.
- Complementary and Integrative Medicine
The Complementary and Integrative Medicine Program was founded by the Department of Medicine at Mayo Clinic in July 2001. The vision of the program is to apply the Mayo model of research, education, and patient care to the realm of complementary and integrative medicine via an evidence-based approach. Many studies have been conducted and numerous studies are ongoing.
- Mayo Institutional Review Board (IRB)
The Mayo Foundation IRB reviews all human subject research conducted at Mayo Clinic in Jacksonville ,Mayo Clinic in Rochester, and Mayo Clinic in Scottsdale and research conducted at other facilities under the direction of the staff at those three facilities. A guarantee that all human subject research at Mayo Clinic will be reviewed by the IRB has been given to the U.S. Department of Health and Human Services (HHS) in a Federal Wide Assurance (FWA00005001). The Mayo IRB provides a wealth of online resources and downloadable forms for all components of research proposals.
- Mayo Clinic Libraries
The collections of Mayo Clinic Libraries cover the entirety of clinical medicine, biomedical research areas and allied fields. They comprise approximately 350,000 volumes and subscriptions to 4,300 scientific, technical and medical periodicals. More than 3,000 journals are available electronically at the desktop.
The following library electronic resources are fully accessible from workstations throughout Mayo Clinic:
- Literature search - a bibliographic retrieval system supporting 10 databases called Mayo Search is based on the Ovid Technologies, Inc.™ product.
- Library Support - consultations with search specialists on research strategy or specialist-performed searches are available at no charge.
- Clinical reference - multiple clinical references are available, including UpToDate™, MDConsult™, Scientific American Online™, and Cochrane Databases™.
- Drug reference - a full-text drug information system with the Micromedex suite of databases and systems as the primary content is also available. Drug Facts & Comparisons is also available electronically.
- Requests for publications - Mayo Clinic libraries are fully automated utilizing the Innovative Interfaces, Inc. product for acquisitions, cataloging, serials control, reserves, media booking and the online catalog.
Computer Services
Over 18,000 computer workstations are available throughout Mayo Clinic. You will have access to computerized intensive care units, a computerized medical record system, computerized laboratory results, computerized retrieval and review of radiological studies, and computerized literature/textbook access.
Faculty
In addition to caring for patients in their clinical practices, Mayo Clinic's faculty members are committed to teaching and facilitating the growth of medical knowledge. Mayo Clinic employs 580 full-time Internal Medicine faculty, many of whom are recognized leaders in their field. You will have direct access to these individuals throughout your training.
Advisers
You will be assigned a faculty advisor who can provide comprehensive educational advice and personal support. Your adviser also will serve as a contact point, introducing you and your family to Rochester and the Mayo Clinic system.
Visiting Professors
Many prominent professors visit Mayo Clinic each year. They present their work during noon and/or morning lectures and participate in hospital rounds. You will be encouraged to take advantage of these opportunities.
Also see: Research
at Mayo Clinic.
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