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Recent Thesis Topics

2014

  • "Novel Mechanisms of Disease Pathogenesis and Penetrance in Potassium Channel-Mediated Heritable Cardiac Arrhythmia Syndromes," John R. Giudicessi, M.D., Ph.D. (Mentor: Michael J. Ackerman, M.D., Ph.D.)

2013

  • "FKBP5 Pharmacogenomics and Functional Genomics," Katarzyna (Kasia) Ellsworth, Ph.D. (Mentor: Liewei Wang, M.D., Ph.D.)
  • "Striatal Dopamine- and Adenosine-Mediated Signaling in Alcohol Use Disorders," Tae-Hyun Kim, Ph.D. (Mentor: Doo-Sup Choi, Ph.D.)
  • "Brugada Syndrome — Genetic Testing Insights and the Molecular Elucidation and Functional Characterization of a Novel Pathogenic Substrate," Cherisse A. Marcou, Ph.D. (Mentor: Michael J. Ackerman, M.D., Ph.D.)
  • "Poly(ADP-ribose) Polymerase Inhibition as a Chemotherapeutic Strategy," Anand G. Patel, M.D., Ph.D. (Mentor: Scott H. Kaufmann, M.D., Ph.D.)
  • "Characterizing Casp8p41, a Novel Fragment Produced by HIV-1 Protease, and its Role in HIV-Induced Cell Death," Amy M. Sainski, Ph.D. (Mentor: Andrew D. Badley, M.D.)
  • "The Mechanism of Cytotoxicity of mTOR Dual Inhibitors in Lymphoid Malignancies," Seong Seok Yun, Ph.D. (Mentor: Scott H. Kaufmann, M.D., Ph.D.)

2012

  • "The Role of Purinergic Signaling on Deformation Induced Injury and Repair Responses of Alveolar Epithelial Cells," Hewan A. Belete, Ph.D. (Mentor: Rolf D. Hubmayr, M.D.)
  • "Mechanisms Contributing to Epigenetic Inheritance and the Maintenance of Genome Integrity in S. Cerevisiae," Rebecca J. Burgess, Ph.D. (Mentor: Zhiguo Zhang, Ph.D.)
  • "JPH2-Encoded Junctophilin 2 and the Pathogenesis of Calcium-Mediated Hypertrophic Cardiomyopathy," Andrew P. Landstrom, M.D., Ph.D. (Mentor: Michael J. Ackerman, M.D., Ph.D.)
  • "Regulation and Function of the RhoGEF Plekhg5 in Intercellular Junction Formation and Monolayer Integrity," Siu P. Ngok, Ph.D. (Mentor: Panagiotis Z. Anastasiadis, Ph.D.)
  • "Methionine Adenosyltransferase Pharmacogenomics," Kendra K.S. Nordgren, Ph.D. (Mentor: Richard Weinshilboum, M.D.)
  • "Optimization of VSV-Mediated Virotherapy in an Immunocompetent Model," Diana M. Rommelfanger-Konkol, Ph.D. (Mentor: Richard G. Vile, Ph.D.)
  • "The Cardiac Sodium Channel Macromolecular Complex and Sudden Infant Death Syndrome," David W. Van Norstrand, M.D., Ph.D. (Mentor: Michael J. Ackerman, M.D., Ph.D.)

2011

  • "A Novel GLI1-Smad4 Transcriptional Complex Modulates TGF-beta Activity" Monica D. Nye, Ph.D.
  • "Regulation of the Proapoptotic BH3-only Proteins Noxa and Puma in Response to Drug-Induced Apoptosis" Alyson J. Smith, Ph.D.
  • "Pharmacogenetics and Pharmacogenomics of Mycophenolic Acid" Tse-Yu Wu, Ph.D.

Other past topics

  • "Rational Induction of Cardiopoietic Progenitors for Heart Regeneration" Anca Chiriac, M.D., Ph.D.
  • "KATP channel deficient heart proteome: Disease susceptibility forecast and therapy prognosis" Jelena Zlatkovic Lindor, Ph.D.
  • "A Study of Therapy-Induced Apoptosis Using Annexin V Binding and Other Assays Less Prone to Artifacts" Sun-Hee Lee, Ph.D.
  • "Mechanisms of Cargo Selection by the Multivesicular Body Pathway" Andrea J. Oestreich, Ph.D.
  • "Mutations and Beyond: Exploring the Relationships Between Genetic Variation, Anatomic Morphology, Gender, and Protein Expression in Hypertrophic Cardiomyopathy" Jeanne L. Theis, Ph.D.
  • "The Role of the HSF-1-mediated Stress Response in Hsp90-directed Therapy Resistance" Andrea K. McCollum, Ph.D.
  • "MTHFR and CYP19A1 (Aromatase) Pharmacogenomics: Genotype-to-Phenotype Studies" Yvette N. Martin, M.D., Ph.D.
  • "Phase II Pharmacogenomics" Yuan Ji, Ph.D.
  • "Microcephalin/MCPH1 in DNA Damage and Chromosome Dynamics" Jamie L. Wood, Ph.D.
  • April 3, 2015
  • ART906878