Mayo Clinic anatomic pathologist examining specimens in laboratory

Program description

The mission of the Anatomic and Clinical Pathology Residency at Mayo Clinic's campus in Rochester, Minnesota, is to provide outstanding education and practical experience in every aspect of laboratory medicine and pathology, in order to prepare graduates to excel in any practice setting.

The program offers three tracks:

  • Anatomic and Clinical Pathology Residency (AP/CP) — five residency positions each year
  • Anatomic and Neuropathology Pathology Pathway (AP/NP) — one position each year
  • Physician-Scientist Research — one position each year

For those interested in devoted time for basic, translational or clinical research, up to six months of electives during residency training can be devoted to research. In addition, a Physician-Scientist Research track is available that offers one or two years of training dedicated to research, typically after the second year of residency training. The Physician-Scientist trainee will select a specific pathway from these available tracks:

  • Anatomic and Clinical Pathology
  • Anatomic Pathology
  • Clinical Pathology

Some of the highlights of training in our program include:

  • Access to material received through our highly active surgical pathology consult practice (more than 60,000 expert consultations a year).
  • Access to laboratory specimens received through Mayo Medical Laboratories.
  • Access to consultative expertise and cutting-edge technologies required to evaluate those specimens.
  • A small residency class size (28 total residents) relative to the faculty size (52 anatomic pathology faculty members and 58 clinical pathology faculty members).
  • Extensive curriculum of lectures, conferences, journal clubs and seminars.
  • Intensive training in the unique Mayo Clinic frozen section laboratory. The frozen section method was developed at Mayo and has been successfully utilized ever since. Learn more about our frozen section laboratory by reading our rotation descriptions and frequently asked questions.
  • Unique seminars in the Department of Laboratory Medicine and Pathology's Leadership and Management Course. Mayo Clinic is committed to training future leaders in medicine and has worked with our department to develop a curriculum in leadership and management specifically geared for pathology residents and fellows.
  • Numerous fellowship training programs offered in the department.
  • Elective rotations at Mayo Clinic's campuses in Phoenix/Scottsdale, Arizona, and Jacksonville, Florida. Community pathology rotations are also available in southeast Minnesota or Wisconsin with the Mayo Clinic Health System.

Each year, the Division of Anatomic Pathology evaluates more than 110,000 surgical and consult specimens and performs more than 700 autopsies. The annual cytopathology case workload is more than 60,000 specimens a year. More than 20 million laboratory tests are performed in Mayo Clinic laboratories annually.


This residency is fully accredited by the Accreditation Council for Graduate Medical Education (ACGME).


After successfully completing residency in AP/CP, AP/NP, or AP or CP only (available in Physician-Scientist Research track), you are eligible to take the certification examination offered by the American Board of Pathology.

Program history

The Anatomic and Clinical Pathology Residency at Mayo Clinic in Rochester, Minnesota, was accredited in 1953. We anticipate that seven trainees will complete this program annually.

Aug. 11, 2017