Mayo Clinic's residency program in medical clinical genetics will prepare you for a career in private practice or academic medicine. The two years of training will include:

  • Inpatient and outpatient medical genetic evaluation
  • Prenatal, pediatric and adult genetic evaluation
  • Genetic counseling

Clinical Training

First Year (PGY-3 or PGY-4)
Clinical Service 9 months
Cytogenetic Laboratory 1 months
Biochemical laboratory 1 months
Molecular Laboratory 1 months
Second Year (PGY-4 or PGY-5)
Clinical Service 9 months
Elective Rotation 3 months
(Elective rotation may include Cytogenetic, Molecular and/or Biochemical laboratories, Clinical Service or research projects)


During PGY-3/4 and PGY-4/5, at least three months of laboratory time is targeted to the acquisition of the clinical application of laboratory testing.

Didactic Training

Clinical conferences, seminars, small discussion groups, journal clubs and one-on-one instruction are all an integral part of the Medical Genetics Residency Program.

The following schedule shows an example of the conferences and seminars that all genetics residents are expected to attend. In addition, clinical, molecular, cytogenetic and biochemical staff, including genetic counselors, graduate students and genetic statisticians and epidemiologists, endocrinologists and neurologists with special interest in metabolic disorders may attend.

Monday: (Weekly) Seminar on Principles of Human and Medical Genetics
Tuesday: (Weekly) Case Conference
Thursday: (Weekly) Journal Club
Friday: (Alternating Weekly) Research Symposium Biochemical Genetics Laboratory Conference

In addition to these conferences directly related to medical genetics, there are teaching conferences hosted throughout the year by the Department of Immunology, Molecular Medicine, Biochemistry/Molecular Biology, Internal Medicine, Pediatrics and others that are attended on an ad hoc basis by clinical genetics staff and residents.

Research Training

You are encouraged to participate in research projects with the consulting staff. This includes opportunities for clinical studies and laboratory-based projects. Although a research track is not available, an additional year of full-time research is a possible option if funding sources can be identified.

You are encouraged to present your research at regional and national meetings. If you are selected to make a presentation, Mayo Clinic will pay the authorized expenses for you to attend that meeting (within the United States). One trip (up to five days) "for attendance only" is provided.

Case Studies

There are a wide variety of clinical cases that are appropriate for reporting in the medical genetics literature.

Teaching Opportunities

You will have the opportunity to teach Mayo Clinic School of Medicine students, visiting students from other medical schools and residents from other specialty areas through bedside instruction, formal didactic lectures, and participation in small group exercises and tutorials.

Call Frequency

Your call schedule will vary by individual rotation. Mayo Clinic follows the recommendations of the ACGME. There is no in-house call.

Medical Genetics Residency Program residents are on home call via pager during the clinical rotation for weekend and night emergencies. A staff consultant is always on call to support the resident.

Committee Assignments

You will be given an opportunity to gain experience in a number of administrative capacities during your training. For example, participation on the Quality Assurance Committee and Department meetings will provide you with experience in quality assessment of clinical care issues and genetic testing.

Moonlighting Policy

Moonlighting is permitted during this residency, following the Mayo Clinic School of Graduate Medical Education general guidelines. This must be approved by the program director.


To ensure that you acquire adequate knowledge and develop your technical skills, your performance will be monitored carefully during the course of your Medical Genetics Residency Program. You will be evaluated on the ACGME competencies as they relate to medical genetics. In addition, you will regularly evaluate the faculty to ensure that your educational needs are being met.

Career Development

You will meet periodically with various faculty members, administrators and the program director to discuss your career goals. Mayo Clinic recruits many of its staff physicians from its own training programs. Thus, when you successfully complete the Medical Genetics Residency Program, job opportunities may be available at one of Mayo Clinic's group practices.

Additional Training

At the conclusion of the Medical Genetics Residency Program, you can continue your training with Mayo Clinic School of Graduate Medical Education. The Department of Medical Genetics, in conjunction with the Section of Laboratory Medicine, Department of Laboratory Medicine/Pathology offers advanced residency training in clinical cytogenetics, molecular genetics, and biochemical genetics.

If you are accepted for a fellowship, you will continue to receive in-depth, daily, one-on-one training with a consultant. You also will also have the opportunity to increase your own supervisory and administrative skills.