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High-Impact Pilot and Feasibility Award (HIPFA)

Note: This award will not be offered in 2014.

The High-Impact Pilot and Feasibility Award (HIPFA) from the Mayo Clinic Center for Clinical and Translational Science (CCaTS) offers funds to support research areas that are novel either to Mayo Clinic or to the investigative team, and that have the potential for high impact on patient care in a timely manner.

Funds need to be available in a timely manner for focused projects that can allow investigators to produce pilot data and demonstrate feasibility for novel research directions in translational research. Junior investigators need funding to support applications for extramural funding, while experienced researchers pursuing highly promising new research directions must test their ideas for feasibility before committing time and resources to a large extramural grant application.

The scope of projects supported by this award mechanism may include any step of the translational research continuum, ranging from the initial translation of discoveries to the evaluation of population health outcomes. Although the intent of the HIPFA is to produce preliminary data that will support extramural grant applications, each project should be of sufficient scope to be a standalone research effort that could generate publications.

The CCaTS Executive Committee may use a Request for Proposals (RFP) process to encourage projects in areas of priority interest.


This award will not be offered in 2014.


  • Consultants, senior associate consultants, and associate consultants in Rochester are eligible for this award
  • Investigators may not hold more than one concurrent HIPFA


  • Awards of up to $30,000 in direct costs for study-related expenses; investigator's effort will not be supported
  • Protocol duration of one year
  • Funds must be spent within the one-year award period — no extensions will be granted
  • No travel expenses will be funded; computers or laptops will generally not be funded

Review criteria

  • Scientific merit, with a strong emphasis on impact and innovation
  • Degree to which the project represents a novel research direction for Mayo Clinic or the investigative team
  • Likelihood of future extramural funding
  • Feasibility within the time and budget proposed
  • Qualifications of the investigators
  • Evidence of plans for multidisciplinary collaboration or inclusion of translational elements
  • Responsiveness to RFP, if applicable

Additional resources

  • April 25, 2014
  • ART887056