Share on:

Bioinformatics Software

The Center for Translational Science Activities (CTSA) and the Division of Biomedical Statistics and Informatics at Mayo Clinic collaborate to offer a series of online professional development courses on bioinformatics software.

These courses are intended for researchers who want to learn about the technologies available in the Medical Genome Facility (formerly the Advanced Genomics Technology Center) at Mayo Clinic and receive training on commercial and public bioinformatics software, public bioinformatics databases and genome browsers.

Effective use of bioinformatics software enables researchers to study — on a genome-wide scale — gene expression, exon composition of transcripts, protein binding sites, genotypes, gene copy number variations, DNA methylation and other molecular events.

All courses in this series are developed by Alexey Leontovich, Ph.D., of Mayo Clinic in Rochester, Minn., who also oversees bioinformatics consulting in the CTSA.

CME: College of Medicine, Mayo Clinic, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. College of Medicine, Mayo Clinic, designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

"Essentials of Microarray Technology"

  • High-throughput microarray technologies enable researchers to study gene expression, exon composition of transcripts, protein binding sites, SNPs, gene copy number variations and other molecular events on the genome-wide scale. There are numerous platforms, but each follows a similar basic concept that must be understood to allow researchers to design quality experiments. Released Jan. 1, 2013; credit expires Dec. 31, 2013.
  • Mayo Clinic employees: Enroll now
  • Non-Mayo participants: Enroll now

"Essentials of Microarray Technology: Affymetrix and Illumina Platforms"

  • High-throughput microarray technologies enable researchers to study gene expression, exon composition of transcripts, protein binding sites, SNPs, gene copy number variations and other molecular events on the genome-wide scale. Although there are multiple platforms implementing this technology, there are a number of key principles that are critical for understanding its potential as well as its limits.

    Affymetrix has additional arrays that can be utilized to ask specific questions of a sample. Illumina microarray technology has proven to be one of the best platforms for gene expression profiling, microRNA and DNA methylation profiling, and SNP detection.

    This lecture explains key principles and features of Affymetrix microarray technology, the background between exon arrays and tiling arrays using Affymetrix technology, and key principles and features of Illumina microarray technology. It also provides background information on learning how to analyze Illumina data. Released Jan. 1, 2013; credit expires Dec. 31, 2013.

  • Mayo Clinic employees: Enroll now
  • Non-Mayo participants: Enroll now

"Obtaining Data and Gene Expression Profiles from Gene Expression Omnibus Microarray Database and File Decompression"

  • Gene Expression Omnibus (GEO) is a free database maintained by the National Center for Biotechnology Information (NCBI) that holds thousands of datasets from published expression data. Public microarray databases are online repositories of microarray data of different types (gene expression, exon arrays and SNPs). They are often supplied with some data analysis and/or visualization tools.

    These databases contain data generated with different microarray platforms, including spotted arrays, Affymetrix, Illumina and Agilent. Researchers can use this site to gather preliminary data on a gene or genes of interest. This lecture explains how to obtain experimental data from public databases, search for genes of interest and download them. Released Jan. 1, 2013; credit expires Dec. 31, 2013.

  • Mayo Clinic employees: Enroll now
  • Non-Mayo participants: Enroll now

"Using Partek Genomics Suite for Microarray Data Analysis: The Basics"

  • Partek GS is an excellent software application for the analysis of gene expression, exon composition of transcripts, copy number variation, gene annotation and more. This is an introductory-level lecture that covers basic functionalities of the software. Released Jan. 1, 2013; credit expires Dec. 31, 2013.
  • Mayo Clinic employees: Enroll now
  • Non-Mayo participants: Enroll now

"Using Ingenuity Pathway Analysis Software for Gene Pathways Analysis"

  • Ingenuity Pathway Analysis is one of the main software applications for the analysis of molecular pathways, biological networks of genes and proteins, data mining of biological annotations, data visualization, and reporting tools. This is an introductory-level tutorial that explains how to use the basic functionalities of the software. Released Jan. 1, 2013; credit expires Dec. 31, 2013.
  • Mayo Clinic employees: Enroll now
  • Non-Mayo participants: Enroll now

Contact

Our Education Contacts page contains a listing of team members who can assist you with questions.

  • March 5, 2013
  • ART503730