The KL2 Mentored Career Development Program has three major parts: a mentored research component, a didactic component and a mentoring component. Together, these components enable you to acquire and refine a set of core competencies.
These competencies reflect an overarching and integrated set of skills, which goes beyond the objectives of individual courses and represents the core knowledge and skills needed for you to become a productive clinical and translational investigator.
As final confirmation that you have mastered these competencies, you are required to prepare and submit a grant application (independent K or R01 or equivalent) to a peer-reviewed funding agency. The research you conduct as a KL2 scholar provides the basis for this grant application.
The following core competencies as defined by the National Institutes of Health (NIH) and the Center for Clinical and Translational Science (CCaTS) are:
- Knowledge within your chosen field of research
- Hypothesis generation
- Universal research methods
- Laboratory methods
- Behavioral methods
- Biostatistical methods
- Research ethics
- Research regulations
- Multidisciplinary research team member
- Multidisciplinary research team leadership
- Results reporting
- Translating new knowledge to routine care
- Competitive grant proposals
- Health disparities
As a KL2 scholar, you will participate in a structured, mentored clinical or translational research project. Your project may relate to any stage of translation, ranging from early-stage (applying discoveries generated during laboratory and preclinical research to the development of trials and studies in humans) to late-stage (enhancing the adoption of best practices in the community) translation.
This research component will form the foundation of your future career development, specifically by providing preliminary data and a publication record to support extramural grant applications.
As you progress through the KL2 Program, you will present at the KL2 Scholar Forum, the CCaTS Postdoctoral Programs Committee and CCaTS Grand Rounds. You are also expected to prepare and submit two to three first-author journal articles.
For more information on the KL2 Program's research component, review the research requirements.
The NIH requires that you cite the Clinical and Translational Science Award (CTSA) if you receive funding through CCaTS or used any CCaTS services to support your research. Read more about properly Citing CCaTS in Publications.
Publications supported by CCaTS must be submitted to PubMed Central and be assigned a PubMed Central ID (PMCID). For instructions, visit the Mayo Clinic Public Access Policy intranet site (must be logged in to the Mayo network) or view this 12-minute step-by-step video.
Once admitted to the KL2 Program, you will meet with your mentoring team and program leadership to develop an individualized action plan and timeline for your career development plan.
Program requirements include the following six credits:
|CTSC 5300: Introduction to Clinical Epidemiology
|CTSC 5310: Clinical Epidemiology II
|CTSC 5600: Statistics in Clinical Research
|CORE 6000: Responsible Conduct of Research
|CTSC 5080: Introduction to Health Disparities
Working with your mentors and CCaTS staff, you will identify additional graduate-level clinical and translational research course work that will enable you to achieve the core competencies as well as your own didactic goals.
Didactic opportunities include a postdoctoral master's degree or certificate in clinical and translational science.
Read more about the Postdoctoral Master's Degree Program and Postdoctoral Certificate Program.
An important and unique aspect of the KL2 Mentored Career Development Program is its mentoring component. Identify your mentor — a Mayo Clinic faculty member — before applying to the program.
The mentor-mentee relationship forms the basis for your growth as an independent clinical and translational investigator. Your mentor will also play a vital role in fostering your career development, such as by helping you identify and pursue relevant educational and training opportunities.
Read more about the KL2 Program's mentoring expectations.